AU2006336552B2 - Diagnostic and therapeutic targets for leukemia - Google Patents
Diagnostic and therapeutic targets for leukemia Download PDFInfo
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- AU2006336552B2 AU2006336552B2 AU2006336552A AU2006336552A AU2006336552B2 AU 2006336552 B2 AU2006336552 B2 AU 2006336552B2 AU 2006336552 A AU2006336552 A AU 2006336552A AU 2006336552 A AU2006336552 A AU 2006336552A AU 2006336552 B2 AU2006336552 B2 AU 2006336552B2
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- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
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- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
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Landscapes
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| US20130102477A1 (en) | 2010-06-23 | 2013-04-25 | Ryan D. Morin | Biomarkers for non-hodgkin lymphomas and uses thereof |
| AU2011298987B2 (en) | 2010-09-10 | 2017-09-28 | Epizyme, Inc. | Inhibitors of human EZH2, and methods of use thereof |
| US9175331B2 (en) | 2010-09-10 | 2015-11-03 | Epizyme, Inc. | Inhibitors of human EZH2, and methods of use thereof |
| JO3438B1 (ar) | 2011-04-13 | 2019-10-20 | Epizyme Inc | مركبات بنزين مستبدلة بأريل أو أريل غير متجانس |
| TWI598336B (zh) | 2011-04-13 | 2017-09-11 | 雅酶股份有限公司 | 經取代之苯化合物 |
| RU2658911C2 (ru) | 2012-04-13 | 2018-06-26 | Эпизайм, Инк. | Солевая форма ингибитора гистон-метилтрансферазы ezh2 человека |
| AU2013331380B2 (en) | 2012-10-15 | 2018-03-22 | Epizyme, Inc. | Substituted benzene compounds |
| JP6639390B2 (ja) * | 2013-08-02 | 2020-02-05 | メモリアル スローン ケタリング キャンサー センター | Ｄｏｔ１ｌ阻害に反応する白血病の検出および治療方法 |
| EP4324525A3 (en) | 2013-10-16 | 2024-07-17 | Epizyme, Inc. | Hydrochloride salt form for ezh2 inhibition |
| EP3911418A1 (en) * | 2019-01-15 | 2021-11-24 | PTC Therapeutics, Inc. | Method for treating an acute myeloid leukemia |
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| US5288514A (en) | 1992-09-14 | 1994-02-22 | The Regents Of The University Of California | Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support |
| US5525735A (en) | 1994-06-22 | 1996-06-11 | Affymax Technologies Nv | Methods for synthesizing diverse collections of pyrrolidine compounds |
| US5525734A (en) | 1994-06-22 | 1996-06-11 | Affymax Technologies N.V. | Methods for synthesizing diverse collections of pyrrolidine compounds |
| US5817751A (en) | 1994-06-23 | 1998-10-06 | Affymax Technologies N.V. | Method for synthesis of diketopiperazine and diketomorpholine derivatives |
| AU7829398A (en) * | 1997-06-09 | 1998-12-30 | University Of Southern California | A cancer diagnostic method based upon dna methylation differences |
| US6555329B2 (en) * | 2000-06-09 | 2003-04-29 | Boehringer Ingelheim International Gmbh | Method for identifying compounds altering higher-order chromatin-dependent chromosome stability |
| WO2003016497A2 (en) | 2001-08-17 | 2003-02-27 | Incyte Genomics, Inc. | Molecules for disease detection and treatment |
| US7485414B2 (en) * | 2002-08-30 | 2009-02-03 | Rigel Pharmaceuticals, Inc. | Modulators of angiogenesis |
| DK1791973T3 (da) | 2004-08-31 | 2010-01-25 | Univ North Carolina | DOT1-histonmethyltransferaser som et target til at identificere terapeutiske midler mod leukæmi |
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- 2006-12-06 CA CA002623271A patent/CA2623271A1/en not_active Abandoned
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| US20050048634A1 (en) * | 2003-06-13 | 2005-03-03 | Yi Zhang | DOT1 histone methyltransferases as a target for identifying therapeutic agents for leukemia |
Also Published As
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| WO2007087015A1 (en) | 2007-08-02 |
| JP2009524051A (ja) | 2009-06-25 |
| CA2623271A1 (en) | 2007-08-02 |
| JP5167149B2 (ja) | 2013-03-21 |
| AU2006336552A1 (en) | 2007-08-02 |
| EP1974055A1 (en) | 2008-10-01 |
| EP2730661A1 (en) | 2014-05-14 |
| US20140044740A1 (en) | 2014-02-13 |
| US20090061443A1 (en) | 2009-03-05 |
| US8524467B2 (en) | 2013-09-03 |
| EP1974055A4 (en) | 2010-01-27 |
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