AU2006327973B2 - Cyclic antimicrobial peptides - Google Patents

Cyclic antimicrobial peptides Download PDF

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Publication number
AU2006327973B2
AU2006327973B2 AU2006327973A AU2006327973A AU2006327973B2 AU 2006327973 B2 AU2006327973 B2 AU 2006327973B2 AU 2006327973 A AU2006327973 A AU 2006327973A AU 2006327973 A AU2006327973 A AU 2006327973A AU 2006327973 B2 AU2006327973 B2 AU 2006327973B2
Authority
AU
Australia
Prior art keywords
peptide
peptides
spp
amino acids
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2006327973A
Other languages
English (en)
Other versions
AU2006327973A1 (en
Inventor
Deborah O'neil
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NovaBiotics Ltd
Original Assignee
NovaBiotics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0526120.1A external-priority patent/GB0526120D0/en
Application filed by NovaBiotics Ltd filed Critical NovaBiotics Ltd
Publication of AU2006327973A1 publication Critical patent/AU2006327973A1/en
Application granted granted Critical
Publication of AU2006327973B2 publication Critical patent/AU2006327973B2/en
Priority to AU2012203804A priority Critical patent/AU2012203804B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Toxicology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AU2006327973A 2005-12-22 2006-12-21 Cyclic antimicrobial peptides Ceased AU2006327973B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2012203804A AU2012203804B2 (en) 2005-12-22 2012-06-28 Cyclic antimicrobial peptides

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0526120.1 2005-12-22
GBGB0526120.1A GB0526120D0 (en) 2005-12-22 2005-12-22 Therapeutic peptides
US77650506P 2006-02-24 2006-02-24
US60/776,505 2006-02-24
PCT/GB2006/004890 WO2007072037A1 (en) 2005-12-22 2006-12-21 Cyclic antimicrobial peptides

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2012203804A Division AU2012203804B2 (en) 2005-12-22 2012-06-28 Cyclic antimicrobial peptides

Publications (2)

Publication Number Publication Date
AU2006327973A1 AU2006327973A1 (en) 2007-06-28
AU2006327973B2 true AU2006327973B2 (en) 2012-04-12

Family

ID=37836928

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2006327973A Ceased AU2006327973B2 (en) 2005-12-22 2006-12-21 Cyclic antimicrobial peptides

Country Status (14)

Country Link
US (2) US8324154B2 (en:Method)
EP (4) EP1976863B1 (en:Method)
JP (3) JP5559477B2 (en:Method)
KR (1) KR101413746B1 (en:Method)
AU (1) AU2006327973B2 (en:Method)
CA (1) CA2655448C (en:Method)
CY (1) CY1113770T1 (en:Method)
IL (2) IL192373A (en:Method)
MX (1) MX2008008291A (en:Method)
NO (1) NO346186B1 (en:Method)
PL (1) PL1976863T3 (en:Method)
RU (1) RU2463308C2 (en:Method)
WO (1) WO2007072037A1 (en:Method)
ZA (1) ZA200806329B (en:Method)

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KR101413746B1 (ko) * 2005-12-22 2014-07-01 노바바이오틱스 리미티드 고리형 항균 펩타이드
GB0702020D0 (en) * 2007-02-02 2007-03-14 Novabiotics Ltd Peptides and their use
US8754039B2 (en) 2009-01-06 2014-06-17 C3 Jian, Inc. Targeted antimicrobial moieties
EP2694085A4 (en) * 2011-04-01 2015-02-11 Univ Northeastern PROCESS FOR EXPLORING BACTERIAL CELL POPULATIONS
WO2013096823A1 (en) * 2011-12-21 2013-06-27 Regents Of The University Of Minnesota Cationic peptides and use of such peptides for inhibiting exotoxin production
KR101502797B1 (ko) * 2012-08-22 2015-03-17 연세대학교 산학협력단 신규한 양친매성　고리형 펩티드, 이의 제조방법 및 이를 포함하는 안정한 자기조립 나노전달체
US9082888B2 (en) 2012-10-17 2015-07-14 New York University Inverted orthogonal spin transfer layer stack
US10815276B2 (en) 2014-05-21 2020-10-27 Entrada Therapeutics, Inc. Cell penetrating peptides and methods of making and using thereof
HUE045872T2 (hu) 2014-05-21 2020-01-28 Entrada Therapeutics Inc Sejteket penetráló peptidek és ezek elõállítására és alkalmazására szolgáló eljárások
WO2016033368A1 (en) 2014-08-27 2016-03-03 Ohio State Innovation Foundation Improved peptidyl calcineurin inhibitors
CA2981705A1 (en) * 2015-03-23 2016-09-29 Riptide Bioscience, Inc. Antimicrobial peptides and methods of use thereof
KR101692992B1 (ko) 2015-05-20 2017-01-17 연세대학교 산학협력단 고리형 펩타이드의 사전 활성화 합성방법 및 이에 따라 합성된 고리형 펩타이드
WO2019070962A1 (en) 2017-10-04 2019-04-11 Ohio State Innovation Foundation BICYCLIC PEPTIDE INHIBITORS
US11576946B2 (en) 2018-01-29 2023-02-14 Ohio State Innovation Foundation Peptidyl inhibitors of calcineurin-NFAT interaction
WO2019148195A2 (en) 2018-01-29 2019-08-01 Ohio State Innovation Foundation Cyclic peptidyl inhibitors of cal-pdz binding domain
TW201945014A (zh) 2018-02-22 2019-12-01 美商安卓達治療股份有限公司 用於治療粒線體性神經胃腸腦病變之組合物及方法
EP3790890A4 (en) 2018-05-09 2022-03-02 Ohio State Innovation Foundation CYCLIC PEPTIDES OF CELL PENETRATION WITH ONE OR MORE HYDROPHOBIC RESIDUES
GB202010268D0 (en) * 2020-07-03 2020-08-19 Novabiotics Ltd Nail formulations and treatment regimes
CN115716865B (zh) * 2022-11-24 2024-04-30 安徽农业大学 具有肝癌细胞毒性和α-葡萄糖苷酶抑制活性的环色-苏-酪-缬-亮肽及制备方法

Citations (3)

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WO1995003327A2 (en) * 1993-07-26 1995-02-02 Biosynth S.R.L. Peptides for neutralizing the toxicity of lipid a
US6156730A (en) * 1993-03-12 2000-12-05 Xoma Corporation Anti-fungal peptides
WO2004050685A2 (en) * 2002-11-29 2004-06-17 Adaptive Therapeutics, Inc. Antifungal therapeutic agents

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US4051842A (en) 1975-09-15 1977-10-04 International Medical Corporation Electrode and interfacing pad for electrical physiological systems
DE2626348C3 (de) 1976-06-11 1980-01-31 Siemens Ag, 1000 Berlin Und 8000 Muenchen Implantierbare Dosiereinrichtung
US4383529A (en) 1980-11-03 1983-05-17 Wescor, Inc. Iontophoretic electrode device, method and gel insert
US4962091A (en) 1986-05-23 1990-10-09 Syntex (U.S.A.) Inc. Controlled release of macromolecular polypeptides
DK0752885T3 (da) 1992-09-25 2003-11-03 Neorx Corp Terapeutisk inhibitor for celler i den glatte karmuskulatur
DE19534177A1 (de) * 1995-09-15 1997-03-20 Merck Patent Gmbh Cyclische Adhäsionsinhibitoren
US5916872A (en) * 1996-07-24 1999-06-29 Intrabiotics Pharmaceuticals, Inc. Cyclic peptides having broad spectrum antimicrobial activity
US6096707A (en) * 1997-07-11 2000-08-01 Biotie Therapies Ltd. Integrin binding peptide and use thereof
US6951652B2 (en) * 1998-07-29 2005-10-04 Biosynth S.R.L. Vaccine for prevention of gram-negative bacterial infections and endotoxin related diseases
CA2446322A1 (en) * 2001-05-04 2002-11-14 M. Reza Ghadiri Anti-microbial peptides and compositions
US7033991B2 (en) * 2001-07-16 2006-04-25 Board Of Supervisors Of Louisiana State University And Agriculture And Mechanical College Inhibiting furin with polybasic peptides
WO2003093300A2 (en) * 2002-05-06 2003-11-13 The Scripps Research Institute Anti-microbial peptides and compositions
US6783677B1 (en) * 2003-02-06 2004-08-31 Mayyar Systems, Inc. Anaerobic film biogas digester system
US7671011B2 (en) * 2003-06-19 2010-03-02 Yeda Research & Development Co. Ltd. Antimicrobial and anticancer lipopeptides
BRPI0514420B1 (pt) * 2004-08-18 2022-05-17 Novabiotics Limited Peptídeo, ou um sal farmaceuticamente aceitável do mesmo, e, uso de um peptídeo
KR101413746B1 (ko) * 2005-12-22 2014-07-01 노바바이오틱스 리미티드 고리형 항균 펩타이드

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6156730A (en) * 1993-03-12 2000-12-05 Xoma Corporation Anti-fungal peptides
WO1995003327A2 (en) * 1993-07-26 1995-02-02 Biosynth S.R.L. Peptides for neutralizing the toxicity of lipid a
WO2004050685A2 (en) * 2002-11-29 2004-06-17 Adaptive Therapeutics, Inc. Antifungal therapeutic agents

Also Published As

Publication number Publication date
EP2357190A3 (en) 2011-08-24
IL192373A0 (en) 2008-12-29
RU2008129866A (ru) 2010-01-27
NO346186B1 (no) 2022-04-11
EP2348039A3 (en) 2011-08-24
JP6050096B2 (ja) 2016-12-21
KR20080081062A (ko) 2008-09-05
WO2007072037A1 (en) 2007-06-28
JP2013047268A (ja) 2013-03-07
JP5559477B2 (ja) 2014-07-23
EP2357190A2 (en) 2011-08-17
NO20083245L (no) 2008-09-12
CY1113770T1 (el) 2016-07-27
EP2357191A2 (en) 2011-08-17
EP1976863B1 (en) 2012-12-12
HK1121462A1 (en) 2009-04-24
IL240686A0 (en) 2015-10-29
JP2009520794A (ja) 2009-05-28
JP6199797B2 (ja) 2017-09-20
US8324154B2 (en) 2012-12-04
ZA200806329B (en) 2009-12-30
US20090023641A1 (en) 2009-01-22
PL1976863T3 (pl) 2013-07-31
WO2007072037A9 (en) 2009-03-05
US8785375B2 (en) 2014-07-22
IL192373A (en) 2015-09-24
EP2348039A2 (en) 2011-07-27
RU2463308C2 (ru) 2012-10-10
JP2014167010A (ja) 2014-09-11
CA2655448A1 (en) 2007-06-28
KR101413746B1 (ko) 2014-07-01
CA2655448C (en) 2016-09-06
US20120316103A1 (en) 2012-12-13
IL240686A (en) 2017-07-31
AU2006327973A1 (en) 2007-06-28
MX2008008291A (es) 2008-09-03
EP2357191A3 (en) 2011-08-24
EP1976863A1 (en) 2008-10-08

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired