AU2006247478A1 - Bicyclic derivatives as modulators of ion channels - Google Patents
Bicyclic derivatives as modulators of ion channels Download PDFInfo
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- AU2006247478A1 AU2006247478A1 AU2006247478A AU2006247478A AU2006247478A1 AU 2006247478 A1 AU2006247478 A1 AU 2006247478A1 AU 2006247478 A AU2006247478 A AU 2006247478A AU 2006247478 A AU2006247478 A AU 2006247478A AU 2006247478 A1 AU2006247478 A1 AU 2006247478A1
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- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Psychology (AREA)
- Cardiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Urology & Nephrology (AREA)
- Anesthesiology (AREA)
- Heart & Thoracic Surgery (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68151905P | 2005-05-16 | 2005-05-16 | |
| US60/681,519 | 2005-05-16 | ||
| PCT/US2006/018669 WO2006124744A1 (en) | 2005-05-16 | 2006-05-12 | Bicyclic derivatives as modulators of ion channels |
Publications (1)
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| AU2006247478A1 true AU2006247478A1 (en) | 2006-11-23 |
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| JP (2) | JP2008540661A (enExample) |
| KR (1) | KR20080021030A (enExample) |
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| CA (1) | CA2608599A1 (enExample) |
| IL (1) | IL187382A0 (enExample) |
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| RU (1) | RU2007146769A (enExample) |
| WO (1) | WO2006124744A1 (enExample) |
| ZA (1) | ZA200710332B (enExample) |
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| US7615563B2 (en) * | 2003-08-08 | 2009-11-10 | Gonzalez Iii Jesus E | Compositions useful as inhibitors of voltage-gated sodium channels |
| CN101218235A (zh) | 2005-05-10 | 2008-07-09 | 沃泰克斯药物股份有限公司 | 作为离子通道调控剂的二环衍生物 |
| ZA200802977B (en) * | 2005-09-09 | 2009-08-26 | Vertex Pharma | Bicyclic derivatives as modulators of voltage gated ion channels |
| EP1948597A1 (en) * | 2005-10-21 | 2008-07-30 | Vertex Pharmaceuticals Incorporated | Derivatives for modulation of ion channels |
| WO2007075895A2 (en) * | 2005-12-21 | 2007-07-05 | Vertex Pharmaceuticals Incorporated | Heterocyclic derivatives as modulators of ion channels |
| WO2008101029A2 (en) * | 2007-02-13 | 2008-08-21 | Xenon Pharmaceuticals Inc. | Use of thiazole, oxazole and imidazole compounds for the treatment of sodium channel-mediated diseases or conditions |
| CA2687764A1 (en) | 2007-05-25 | 2008-12-04 | Vertex Pharmaceuticals Incorporated | Ion channel modulators and methods of use |
| US7994174B2 (en) * | 2007-09-19 | 2011-08-09 | Vertex Pharmaceuticals Incorporated | Pyridyl sulfonamides as modulators of ion channels |
| WO2009045381A1 (en) * | 2007-10-04 | 2009-04-09 | Merck & Co., Inc. | N-substituted oxindoline derivatives as calcium channel blockers |
| CN102036985A (zh) | 2007-11-13 | 2011-04-27 | 沃泰克斯药物股份有限公司 | 用于治疗疼痛的作为离子通道调节剂的4(-3-(-2-(苯基)吗啉代)-2-氧代吡咯烷-1-基)-n-(噻唑-2-基)苯磺酰胺衍生物和相关化合物 |
| AU2008321142A1 (en) * | 2007-11-13 | 2009-05-22 | Vertex Pharmaceuticals Incorporated | Heterocyclic derivatives as modulators of ion channels |
| US20110031892A1 (en) * | 2008-04-30 | 2011-02-10 | Sharp Kabushiki Kaisha | Lighting device and display device |
| EP2307412A2 (en) * | 2008-07-01 | 2011-04-13 | Vertex Pharmaceuticals Incorporated | Heterocyclic derivatives as modulators of ion channels |
| US20130109672A1 (en) | 2010-04-29 | 2013-05-02 | The United States Of America,As Represented By The Secretary, Department Of Health And Human Service | Activators of human pyruvate kinase |
| WO2013086229A1 (en) | 2011-12-07 | 2013-06-13 | Amgen Inc. | Bicyclic aryl and heteroaryl sodium channel inhibitors |
| US8889741B2 (en) * | 2012-02-09 | 2014-11-18 | Daiichi Sankyo Company, Limited | Cycloalkane derivatives |
| US9212182B2 (en) | 2013-06-12 | 2015-12-15 | Amgen Inc. | Bicyclic sulfonamide compounds as sodium channel inhibitors |
| MX2016010056A (es) * | 2014-02-06 | 2016-11-15 | Abbvie Inc | 6-heteroariloxi o 6-ariloxi-quinolina-2-carboxamidas y metodos de uso. |
| GB201810092D0 (en) | 2018-06-20 | 2018-08-08 | Ctxt Pty Ltd | Compounds |
| GB201810581D0 (en) | 2018-06-28 | 2018-08-15 | Ctxt Pty Ltd | Compounds |
| AU2019302534B2 (en) | 2018-07-09 | 2024-10-03 | Lieber Institute, Inc. | Pyridazine compounds for inhibiting NaV1.8 |
| SG11202100130QA (en) | 2018-07-09 | 2021-02-25 | Lieber Institute Inc | Pyridine carboxamide compounds for inhibiting nav1.8 |
| SI4299135T1 (sl) | 2019-06-18 | 2025-12-31 | Pfizer Inc. | Benzizoksazolni sulfonamidni derivati |
| JP7739051B2 (ja) | 2020-06-10 | 2025-09-16 | アムジエン・インコーポレーテツド | シクロブチルジヒドロキノリンスルホンアミド化合物 |
| CN115073370B (zh) * | 2021-03-10 | 2024-12-17 | 成都硕德药业有限公司 | 新型烷基氨类化合物或盐、异构体、其制备方法及用途 |
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| US5304121A (en) | 1990-12-28 | 1994-04-19 | Boston Scientific Corporation | Drug delivery system making use of a hydrogel polymer coating |
| US5994341A (en) | 1993-07-19 | 1999-11-30 | Angiogenesis Technologies, Inc. | Anti-angiogenic Compositions and methods for the treatment of arthritis |
| US6099562A (en) | 1996-06-13 | 2000-08-08 | Schneider (Usa) Inc. | Drug coating with topcoat |
| US5869478A (en) | 1995-06-07 | 1999-02-09 | Bristol-Myers Squibb Company | Sulfonamido substituted benzopyran derivatives |
| JP2001513560A (ja) * | 1997-08-28 | 2001-09-04 | ブリストル−マイヤーズ スクイブ カンパニー | ４−アリール−３−アミノキノリン−２−オン誘導体カリウムチャンネル調節剤 |
| GB0217431D0 (en) * | 2002-07-27 | 2002-09-04 | Astrazeneca Ab | Novel compounds |
| US7157577B2 (en) * | 2003-03-07 | 2007-01-02 | Sugen Inc. | 5-sulfonamido-substituted indolinone compounds as protein kinase inhibitors |
| US7009052B2 (en) * | 2003-03-20 | 2006-03-07 | Warner Lambert Company Llc | Sulfonamide derivatives |
| KR20060073930A (ko) | 2003-08-08 | 2006-06-29 | 버텍스 파마슈티칼스 인코포레이티드 | 통증 치료시 나트륨 또는 칼슘 채널 차단제로서 유용한헤테로아릴아미노설포닐페닐 유도체 |
| US7615563B2 (en) | 2003-08-08 | 2009-11-10 | Gonzalez Iii Jesus E | Compositions useful as inhibitors of voltage-gated sodium channels |
| CN101218235A (zh) | 2005-05-10 | 2008-07-09 | 沃泰克斯药物股份有限公司 | 作为离子通道调控剂的二环衍生物 |
| WO2006133459A1 (en) | 2005-06-09 | 2006-12-14 | Vertex Pharmaceuticals Incorporated | Indane derivatives as modulators of ion channels |
| ZA200802977B (en) | 2005-09-09 | 2009-08-26 | Vertex Pharma | Bicyclic derivatives as modulators of voltage gated ion channels |
| US7683083B2 (en) | 2005-10-12 | 2010-03-23 | Vertex Pharmaceuticals Incorporated | Biphenyl derivatives as modulators of voltage gated ion channels |
| EP1948597A1 (en) | 2005-10-21 | 2008-07-30 | Vertex Pharmaceuticals Incorporated | Derivatives for modulation of ion channels |
| WO2007075895A2 (en) | 2005-12-21 | 2007-07-05 | Vertex Pharmaceuticals Incorporated | Heterocyclic derivatives as modulators of ion channels |
| US7994174B2 (en) | 2007-09-19 | 2011-08-09 | Vertex Pharmaceuticals Incorporated | Pyridyl sulfonamides as modulators of ion channels |
| CN102036985A (zh) | 2007-11-13 | 2011-04-27 | 沃泰克斯药物股份有限公司 | 用于治疗疼痛的作为离子通道调节剂的4(-3-(-2-(苯基)吗啉代)-2-氧代吡咯烷-1-基)-n-(噻唑-2-基)苯磺酰胺衍生物和相关化合物 |
| AU2008321142A1 (en) | 2007-11-13 | 2009-05-22 | Vertex Pharmaceuticals Incorporated | Heterocyclic derivatives as modulators of ion channels |
| US8697739B2 (en) * | 2010-07-29 | 2014-04-15 | Novartis Ag | Bicyclic acetyl-CoA carboxylase inhibitors and uses thereof |
-
2006
- 2006-05-12 EP EP06770340A patent/EP1888558B1/en not_active Expired - Lifetime
- 2006-05-12 ZA ZA200710332A patent/ZA200710332B/xx unknown
- 2006-05-12 AU AU2006247478A patent/AU2006247478A1/en not_active Abandoned
- 2006-05-12 US US11/432,997 patent/US7745629B2/en active Active
- 2006-05-12 WO PCT/US2006/018669 patent/WO2006124744A1/en not_active Ceased
- 2006-05-12 CN CNA2006800252561A patent/CN101218226A/zh active Pending
- 2006-05-12 AT AT06770340T patent/ATE527251T1/de not_active IP Right Cessation
- 2006-05-12 JP JP2008512394A patent/JP2008540661A/ja not_active Ceased
- 2006-05-12 KR KR1020077029355A patent/KR20080021030A/ko not_active Withdrawn
- 2006-05-12 CA CA002608599A patent/CA2608599A1/en not_active Abandoned
- 2006-05-12 RU RU2007146769/04A patent/RU2007146769A/ru not_active Application Discontinuation
- 2006-05-12 MX MX2007014486A patent/MX2007014486A/es not_active Application Discontinuation
-
2007
- 2007-11-15 IL IL187382A patent/IL187382A0/en unknown
- 2007-12-14 NO NO20076447A patent/NO20076447L/no not_active Application Discontinuation
-
2010
- 2010-04-16 US US12/761,502 patent/US8314125B2/en active Active
-
2012
- 2012-03-28 JP JP2012074138A patent/JP2012126744A/ja not_active Withdrawn
- 2012-11-16 US US13/679,028 patent/US8536195B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP2008540661A (ja) | 2008-11-20 |
| ATE527251T1 (de) | 2011-10-15 |
| JP2012126744A (ja) | 2012-07-05 |
| WO2006124744A1 (en) | 2006-11-23 |
| NO20076447L (no) | 2008-02-08 |
| EP1888558A1 (en) | 2008-02-20 |
| ZA200710332B (en) | 2009-03-25 |
| US7745629B2 (en) | 2010-06-29 |
| RU2007146769A (ru) | 2009-06-27 |
| EP1888558B1 (en) | 2011-10-05 |
| MX2007014486A (es) | 2008-02-12 |
| US20130084639A1 (en) | 2013-04-04 |
| US8314125B2 (en) | 2012-11-20 |
| US20100204255A1 (en) | 2010-08-12 |
| US8536195B2 (en) | 2013-09-17 |
| CN101218226A (zh) | 2008-07-09 |
| US20080119453A1 (en) | 2008-05-22 |
| CA2608599A1 (en) | 2006-11-23 |
| KR20080021030A (ko) | 2008-03-06 |
| IL187382A0 (en) | 2008-02-09 |
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| EP1891063B1 (en) | Bicyclic derivatives as modulators of ion channels | |
| US7989481B2 (en) | Indane derivatives as modulators of ion channels | |
| US8492403B2 (en) | Bicyclic derivatives as modulators of voltage gated ion channels | |
| AU2006304283B2 (en) | Biphenyl derivatives as modulators of voltage gated ion channels |
Legal Events
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| MK1 | Application lapsed section 142(2)(a) - no request for examination in relevant period |