AU2006216085B2 - Contact lens care composition - Google Patents
Contact lens care composition Download PDFInfo
- Publication number
- AU2006216085B2 AU2006216085B2 AU2006216085A AU2006216085A AU2006216085B2 AU 2006216085 B2 AU2006216085 B2 AU 2006216085B2 AU 2006216085 A AU2006216085 A AU 2006216085A AU 2006216085 A AU2006216085 A AU 2006216085A AU 2006216085 B2 AU2006216085 B2 AU 2006216085B2
- Authority
- AU
- Australia
- Prior art keywords
- composition
- use according
- anyone
- contact lens
- miltefosine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 60
- PQLXHQMOHUQAKB-UHFFFAOYSA-N miltefosine Chemical compound CCCCCCCCCCCCCCCCOP([O-])(=O)OCC[N+](C)(C)C PQLXHQMOHUQAKB-UHFFFAOYSA-N 0.000 claims abstract description 29
- 229960003775 miltefosine Drugs 0.000 claims abstract description 27
- 241000224422 Acanthamoeba Species 0.000 claims abstract description 24
- 239000000126 substance Substances 0.000 claims abstract description 9
- 108091005804 Peptidases Proteins 0.000 claims abstract description 5
- 239000004365 Protease Substances 0.000 claims abstract description 5
- 235000002639 sodium chloride Nutrition 0.000 claims description 10
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 8
- 239000000645 desinfectant Substances 0.000 claims description 8
- 238000004140 cleaning Methods 0.000 claims description 7
- 238000004659 sterilization and disinfection Methods 0.000 claims description 7
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 6
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 6
- -1 alkali metal salts Chemical class 0.000 claims description 5
- 239000001913 cellulose Substances 0.000 claims description 5
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- 230000000249 desinfective effect Effects 0.000 claims description 5
- 229920000642 polymer Polymers 0.000 claims description 5
- 150000003839 salts Chemical class 0.000 claims description 5
- 239000004094 surface-active agent Substances 0.000 claims description 5
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims description 4
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims description 4
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 claims description 4
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- 238000003860 storage Methods 0.000 claims description 3
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 claims description 2
- 239000004372 Polyvinyl alcohol Substances 0.000 claims description 2
- 229910052783 alkali metal Inorganic materials 0.000 claims description 2
- 239000004599 antimicrobial Substances 0.000 claims description 2
- 239000001110 calcium chloride Substances 0.000 claims description 2
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- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 description 2
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- OSVXSBDYLRYLIG-UHFFFAOYSA-N dioxidochlorine(.) Chemical compound O=Cl=O OSVXSBDYLRYLIG-UHFFFAOYSA-N 0.000 description 2
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- YHHSONZFOIEMCP-UHFFFAOYSA-N 2-(trimethylazaniumyl)ethyl hydrogen phosphate Chemical compound C[N+](C)(C)CCOP(O)([O-])=O YHHSONZFOIEMCP-UHFFFAOYSA-N 0.000 description 1
- RXGSAYBOEDPICZ-UHFFFAOYSA-N 2-[6-[[amino-(diaminomethylideneamino)methylidene]amino]hexyl]-1-(diaminomethylidene)guanidine Chemical compound NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)N RXGSAYBOEDPICZ-UHFFFAOYSA-N 0.000 description 1
- BDPQVGIMLZYZQA-UHFFFAOYSA-N 2-hexadecanoylthio-1-ethylphosphorylcholine Chemical compound CCCCCCCCCCCCCCCC(=O)SCCOP([O-])(=O)OCC[N+](C)(C)C BDPQVGIMLZYZQA-UHFFFAOYSA-N 0.000 description 1
- 125000000954 2-hydroxyethyl group Chemical group [H]C([*])([H])C([H])([H])O[H] 0.000 description 1
- RFRMMZAKBNXNHE-UHFFFAOYSA-N 6-[4,6-dihydroxy-5-(2-hydroxyethoxy)-2-(hydroxymethyl)oxan-3-yl]oxy-2-(hydroxymethyl)-5-(2-hydroxypropoxy)oxane-3,4-diol Chemical compound CC(O)COC1C(O)C(O)C(CO)OC1OC1C(O)C(OCCO)C(O)OC1CO RFRMMZAKBNXNHE-UHFFFAOYSA-N 0.000 description 1
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- 229920001817 Agar Polymers 0.000 description 1
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- 241000224489 Amoeba Species 0.000 description 1
- 201000004569 Blindness Diseases 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- 239000004155 Chlorine dioxide Substances 0.000 description 1
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- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 1
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- ABBQHOQBGMUPJH-UHFFFAOYSA-M Sodium salicylate Chemical compound [Na+].OC1=CC=CC=C1C([O-])=O ABBQHOQBGMUPJH-UHFFFAOYSA-M 0.000 description 1
- 206010047505 Visceral leishmaniasis Diseases 0.000 description 1
- 239000006658 acanthamoeba medium Substances 0.000 description 1
- 238000007792 addition Methods 0.000 description 1
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- 239000008272 agar Substances 0.000 description 1
- LFVVNPBBFUSSHL-UHFFFAOYSA-N alexidine Chemical class CCCCC(CC)CNC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NCC(CC)CCCC LFVVNPBBFUSSHL-UHFFFAOYSA-N 0.000 description 1
- 229950010221 alexidine Drugs 0.000 description 1
- 125000000217 alkyl group Chemical group 0.000 description 1
- 125000005037 alkyl phenyl group Chemical group 0.000 description 1
- 125000003277 amino group Chemical group 0.000 description 1
- 125000000129 anionic group Chemical group 0.000 description 1
- 230000002001 anti-metastasis Effects 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
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- 244000052616 bacterial pathogen Species 0.000 description 1
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- 150000004283 biguanides Chemical class 0.000 description 1
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- 239000008280 blood Substances 0.000 description 1
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- 229960002713 calcium chloride Drugs 0.000 description 1
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- 230000003197 catalytic effect Effects 0.000 description 1
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- YZIYKJHYYHPJIB-UUPCJSQJSA-N chlorhexidine gluconate Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.C1=CC(Cl)=CC=C1NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NC1=CC=C(Cl)C=C1 YZIYKJHYYHPJIB-UUPCJSQJSA-N 0.000 description 1
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- GNBHRKFJIUUOQI-UHFFFAOYSA-N fluorescein Chemical compound O1C(=O)C2=CC=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 GNBHRKFJIUUOQI-UHFFFAOYSA-N 0.000 description 1
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- BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 description 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 description 1
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- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 description 1
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- 239000002563 ionic surfactant Substances 0.000 description 1
- 231100001032 irritation of the eye Toxicity 0.000 description 1
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- 238000006386 neutralization reaction Methods 0.000 description 1
- GWUSZQUVEVMBPI-UHFFFAOYSA-N nimetazepam Chemical compound N=1CC(=O)N(C)C2=CC=C([N+]([O-])=O)C=C2C=1C1=CC=CC=C1 GWUSZQUVEVMBPI-UHFFFAOYSA-N 0.000 description 1
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- 239000008188 pellet Substances 0.000 description 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 description 1
- 229950004354 phosphorylcholine Drugs 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 229920001983 poloxamer Polymers 0.000 description 1
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- WSOSYBUSMXEYDO-UHFFFAOYSA-N propamidine isethionate Chemical compound OCCS(O)(=O)=O.OCCS(O)(=O)=O.C1=CC(C(=N)N)=CC=C1OCCCOC1=CC=C(C(N)=N)C=C1 WSOSYBUSMXEYDO-UHFFFAOYSA-N 0.000 description 1
- 229960000771 propamidine isethionate Drugs 0.000 description 1
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- 150000003242 quaternary ammonium salts Chemical class 0.000 description 1
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- AZJPTIGZZTZIDR-UHFFFAOYSA-L rose bengal Chemical compound [K+].[K+].[O-]C(=O)C1=C(Cl)C(Cl)=C(Cl)C(Cl)=C1C1=C2C=C(I)C(=O)C(I)=C2OC2=C(I)C([O-])=C(I)C=C21 AZJPTIGZZTZIDR-UHFFFAOYSA-L 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
- A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
- A61L12/14—Organic compounds not covered by groups A61L12/10 or A61L12/12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
- A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
- A61L12/10—Halogens or compounds thereof
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/0005—Other compounding ingredients characterised by their effect
- C11D3/0078—Compositions for cleaning contact lenses, spectacles or lenses
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/36—Organic compounds containing phosphorus
- C11D3/364—Organic compounds containing phosphorus containing nitrogen
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Eyeglasses (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT0030505A AT501545B1 (de) | 2005-02-23 | 2005-02-23 | Reinigungsmittel für kontaktlinsen |
| ATA305/2005 | 2005-02-23 | ||
| PCT/AT2006/000063 WO2006089320A1 (en) | 2005-02-23 | 2006-02-20 | Contact lens care composition |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2006216085A1 AU2006216085A1 (en) | 2006-08-31 |
| AU2006216085B2 true AU2006216085B2 (en) | 2011-10-20 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2006216085A Ceased AU2006216085B2 (en) | 2005-02-23 | 2006-02-20 | Contact lens care composition |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20080300221A1 (https=) |
| EP (1) | EP1850888B1 (https=) |
| JP (1) | JP4738423B2 (https=) |
| CN (1) | CN101119755A (https=) |
| AT (2) | AT501545B1 (https=) |
| AU (1) | AU2006216085B2 (https=) |
| BR (1) | BRPI0606336A2 (https=) |
| CA (1) | CA2592246C (https=) |
| DE (1) | DE602006002806D1 (https=) |
| EA (1) | EA012285B1 (https=) |
| ES (1) | ES2313607T3 (https=) |
| PL (1) | PL1850888T3 (https=) |
| PT (1) | PT1850888E (https=) |
| WO (1) | WO2006089320A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100086512A1 (en) * | 2008-10-02 | 2010-04-08 | Rolf Schaefer | Mucomimetic compositions and uses therefore |
| US20130005819A1 (en) * | 2009-09-21 | 2013-01-03 | Brien Holden Vision Institute | Contact lens disinfecting solutions |
| WO2013135571A1 (en) | 2012-03-14 | 2013-09-19 | Orphanidis Pharma Research Gmbh | Compositions with enhanced therapeutic efficacy against infective agents of the eye comprising miltefosine and polyhexamethylene biguanide |
| WO2013154209A1 (en) * | 2012-04-12 | 2013-10-17 | Santen Pharmaceutical Co., Ltd. | Antiprotozoan composition containing caspofungin or its salt and biguanide compound or its salt |
| JP2015052505A (ja) * | 2013-09-06 | 2015-03-19 | 株式会社エイコー | アカントアメーバ（・シスト）の生死判別方法 |
| GB2594907B (en) * | 2019-08-15 | 2024-01-31 | Univ Of The West Of Scotland | Composition comprising anti-acanthamoeba agents |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0381617T3 (da) * | 1989-01-31 | 1996-06-10 | Ciba Geigy Ag | Desinfektions- og rensemiddel til kontaktlinser |
| DE4132345A1 (de) * | 1991-09-27 | 1993-04-01 | Max Planck Gesellschaft | Ether-lysolecithine und alkylphosphocholine in liposomen |
| AU677638B2 (en) * | 1993-01-26 | 1997-05-01 | Allergan, Inc. | Compositions and methods to disinfect contact lenses |
| JPH09206362A (ja) * | 1996-02-05 | 1997-08-12 | Tomey Technol Corp | コンタクトレンズ用消毒洗浄組成物及びそれを用いたコンタクトレンズの消毒洗浄方法 |
| GB9606868D0 (en) * | 1996-04-01 | 1996-06-05 | Waverley Pharma Ltd | Disinfectant solutions |
| GB2333609B (en) * | 1998-01-27 | 2002-07-24 | Prof Alan Tomlinson | Salicylate inhibition of amoebic attachment to contact lenses |
| DE10203195A1 (de) * | 2002-01-25 | 2003-08-07 | Zentaris Ag | Verwendung von Alkylphosphocholinen in der Präventivbehandlung von Protozoenerkrankungen |
| US20040063591A1 (en) * | 2002-09-30 | 2004-04-01 | Bausch & Lomb Incorporated | Compositions with enhanced antimicrobial efficacy against acanthamoebae |
| DE10313272A1 (de) * | 2003-03-24 | 2004-10-21 | Baxter Healthcare S.A. | Verwendung von Miltefosine zur Behandlung von aktinischer oder multiplen aktinischer Keratosen |
-
2005
- 2005-02-23 AT AT0030505A patent/AT501545B1/de not_active IP Right Cessation
-
2006
- 2006-02-20 AT AT06704705T patent/ATE408427T1/de active
- 2006-02-20 AU AU2006216085A patent/AU2006216085B2/en not_active Ceased
- 2006-02-20 BR BRPI0606336-5A patent/BRPI0606336A2/pt active Search and Examination
- 2006-02-20 PT PT06704705T patent/PT1850888E/pt unknown
- 2006-02-20 US US11/817,011 patent/US20080300221A1/en not_active Abandoned
- 2006-02-20 ES ES06704705T patent/ES2313607T3/es not_active Expired - Lifetime
- 2006-02-20 EP EP06704705A patent/EP1850888B1/en not_active Expired - Lifetime
- 2006-02-20 DE DE602006002806T patent/DE602006002806D1/de not_active Expired - Lifetime
- 2006-02-20 PL PL06704705T patent/PL1850888T3/pl unknown
- 2006-02-20 WO PCT/AT2006/000063 patent/WO2006089320A1/en not_active Ceased
- 2006-02-20 JP JP2007556459A patent/JP4738423B2/ja not_active Expired - Fee Related
- 2006-02-20 CN CNA2006800052705A patent/CN101119755A/zh active Pending
- 2006-02-20 EA EA200701776A patent/EA012285B1/ru not_active IP Right Cessation
- 2006-02-20 CA CA2592246A patent/CA2592246C/en not_active Expired - Fee Related
Non-Patent Citations (1)
| Title |
|---|
| Walochnik J et al (2002). Cytotoxic activities of alkylphophocholines against clinical isolates of Acanthamoeba spp. Antimicrobial Agents and Chemotherapy, 46(3), 695-701. * |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2592246C (en) | 2013-01-08 |
| PT1850888E (pt) | 2008-11-20 |
| EA012285B1 (ru) | 2009-08-28 |
| ATE408427T1 (de) | 2008-10-15 |
| JP2008532586A (ja) | 2008-08-21 |
| JP4738423B2 (ja) | 2011-08-03 |
| AT501545B1 (de) | 2007-10-15 |
| EA200701776A1 (ru) | 2007-12-28 |
| DE602006002806D1 (https=) | 2008-10-30 |
| BRPI0606336A2 (pt) | 2009-06-16 |
| CA2592246A1 (en) | 2006-08-31 |
| EP1850888A1 (en) | 2007-11-07 |
| EP1850888B1 (en) | 2008-09-17 |
| US20080300221A1 (en) | 2008-12-04 |
| PL1850888T3 (pl) | 2009-02-27 |
| AU2006216085A1 (en) | 2006-08-31 |
| CN101119755A (zh) | 2008-02-06 |
| WO2006089320A1 (en) | 2006-08-31 |
| AT501545A1 (de) | 2006-09-15 |
| ES2313607T3 (es) | 2009-03-01 |
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Legal Events
| Date | Code | Title | Description |
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| FGA | Letters patent sealed or granted (standard patent) | ||
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |