AU2006213985C1 - Pharmacokinetically improved compounds - Google Patents

Pharmacokinetically improved compounds Download PDF

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Publication number
AU2006213985C1
AU2006213985C1 AU2006213985A AU2006213985A AU2006213985C1 AU 2006213985 C1 AU2006213985 C1 AU 2006213985C1 AU 2006213985 A AU2006213985 A AU 2006213985A AU 2006213985 A AU2006213985 A AU 2006213985A AU 2006213985 C1 AU2006213985 C1 AU 2006213985C1
Authority
AU
Australia
Prior art keywords
compound
alkyl
lower alkyl
amino
alkylthio
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
AU2006213985A
Other languages
English (en)
Other versions
AU2006213985A1 (en
AU2006213985B2 (en
Inventor
Stewart Campbell
David Duffy
Michael Grogan
Steven Kates
Emanuele Ostuni
Olivier Schueller
Paul Sweetnam
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Surface Logix Inc
Original Assignee
Surface Logix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Surface Logix Inc filed Critical Surface Logix Inc
Publication of AU2006213985A1 publication Critical patent/AU2006213985A1/en
Assigned to SURFACE LOGIX, INC. reassignment SURFACE LOGIX, INC. Request for Assignment Assignors: CAMPBELL, STEWART, DUFFY, DAVID, GROGAN, MICHAEL, KATES, STEVEN, OSTUNI, EMANUELE, SCHUELLER, OLIVIER, SURFACE LOGIX, INC., SWEETNAM, PAUL
Application granted granted Critical
Publication of AU2006213985B2 publication Critical patent/AU2006213985B2/en
Publication of AU2006213985C1 publication Critical patent/AU2006213985C1/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU2006213985A 2005-02-18 2006-02-21 Pharmacokinetically improved compounds Expired - Fee Related AU2006213985C1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US65393305P 2005-02-18 2005-02-18
US60/653,933 2005-02-18
PCT/US2006/006048 WO2006089276A2 (en) 2005-02-18 2006-02-21 Pharmacokinetically improved compounds

Publications (3)

Publication Number Publication Date
AU2006213985A1 AU2006213985A1 (en) 2006-08-24
AU2006213985B2 AU2006213985B2 (en) 2011-08-25
AU2006213985C1 true AU2006213985C1 (en) 2012-03-15

Family

ID=36917159

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2006213985A Expired - Fee Related AU2006213985C1 (en) 2005-02-18 2006-02-21 Pharmacokinetically improved compounds

Country Status (19)

Country Link
US (2) US20080176844A1 (es)
EP (1) EP1850853A4 (es)
JP (1) JP2008530247A (es)
KR (1) KR20080016531A (es)
CN (2) CN102351862A (es)
AU (1) AU2006213985C1 (es)
BR (1) BRPI0608381A2 (es)
CA (1) CA2598271A1 (es)
CR (1) CR9381A (es)
EA (1) EA018668B1 (es)
GE (1) GEP20115184B (es)
IL (1) IL185344A0 (es)
MX (1) MX2007010144A (es)
NI (1) NI200700210A (es)
NO (1) NO20074742L (es)
NZ (1) NZ560963A (es)
UA (1) UA90502C2 (es)
WO (1) WO2006089276A2 (es)
ZA (1) ZA200707505B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA200707506B (en) * 2005-02-18 2009-08-26 Surface Logix Inc Method of making pharmacokinetically improved compounds comprising functional residues or groups and pharmaceutical compositions comprising said compounds
CR9465A (es) 2005-03-25 2008-06-19 Surface Logix Inc Compuestos mejorados farmacocineticamente
US20120070443A1 (en) * 2008-12-02 2012-03-22 University Of Utah Research Foundation Pde1 as a target therapeutic in heart disease

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH445129A (fr) * 1964-04-29 1967-10-15 Nestle Sa Procédé pour la préparation de composés d'inclusion à poids moléculaire élevé
US3459731A (en) * 1966-12-16 1969-08-05 Corn Products Co Cyclodextrin polyethers and their production
US3426011A (en) * 1967-02-13 1969-02-04 Corn Products Co Cyclodextrins with anionic properties
US3453257A (en) * 1967-02-13 1969-07-01 Corn Products Co Cyclodextrin with cationic properties
US3453259A (en) * 1967-03-22 1969-07-01 Corn Products Co Cyclodextrin polyol ethers and their oxidation products
US4235871A (en) * 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4631211A (en) * 1985-03-25 1986-12-23 Scripps Clinic & Research Foundation Means for sequential solid phase organic synthesis and methods using the same
US4737323A (en) * 1986-02-13 1988-04-12 Liposome Technology, Inc. Liposome extrusion method
US5143854A (en) * 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
KR0166088B1 (ko) * 1990-01-23 1999-01-15 . 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
US5359115A (en) * 1992-03-26 1994-10-25 Affymax Technologies, N.V. Methods for the synthesis of phosphonate esters
US5288514A (en) * 1992-09-14 1994-02-22 The Regents Of The University Of California Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support
US5480971A (en) * 1993-06-17 1996-01-02 Houghten Pharmaceuticals, Inc. Peralkylated oligopeptide mixtures
US5440016A (en) * 1993-06-18 1995-08-08 Torrey Pines Institute For Molecular Studies Peptides of the formula (KFmoc) ZZZ and their uses
US5362899A (en) * 1993-09-09 1994-11-08 Affymax Technologies, N.V. Chiral synthesis of alpha-aminophosponic acids
ATE213246T1 (de) * 1997-11-12 2002-02-15 2-phenyl-substituierte imidazotriazinone als phosphodiesterase inhibitoren
US5958886A (en) * 1998-01-13 1999-09-28 Sigma-Tau Pharmaceuticals, Inc. Carnitine-containing peptides and a method for using the same
DE19827640A1 (de) * 1998-06-20 1999-12-23 Bayer Ag 7-Alkyl- und Cycloalkyl-substituierte Imidazotriazinone
KR100353014B1 (ko) * 1998-11-11 2002-09-18 동아제약 주식회사 발기부전 치료에 효과를 갖는 피라졸로피리미디논 화합물
CA2323008C (en) * 1999-10-11 2005-07-12 Pfizer Inc. Pharmaceutically active compounds
GB9924020D0 (en) * 1999-10-11 1999-12-15 Pfizer Ltd Pharmaceutically active compounds
US6803365B2 (en) * 1999-12-24 2004-10-12 Bayer Aktlengesellschaft Imidazo[1,3,5]triazinones and the use thereof
ES2231311T3 (es) * 1999-12-24 2005-05-16 Bayer Healthcare Ag Triazolotriazinonas y su uso.
US6548508B2 (en) * 2000-10-20 2003-04-15 Pfizer, Inc. Use of PDE V inhibitors for improved fecundity in mammals
DE10107639A1 (de) * 2001-02-15 2002-08-22 Bayer Ag 2-Alkoxyphenyl-substituierte Imidazotriazinone
GB0106661D0 (en) * 2001-03-16 2001-05-09 Pfizer Ltd Pharmaceutically active compounds
US6794387B2 (en) * 2001-03-28 2004-09-21 Pfizer Inc. Pharmaceutically active compounds

Also Published As

Publication number Publication date
EA200701753A1 (ru) 2008-04-28
KR20080016531A (ko) 2008-02-21
CA2598271A1 (en) 2006-08-24
NO20074742L (no) 2007-11-16
CR9381A (es) 2008-06-19
IL185344A0 (en) 2008-02-09
EP1850853A4 (en) 2011-09-07
ZA200707505B (en) 2009-08-26
NI200700210A (es) 2008-07-24
NZ560963A (en) 2010-11-26
US20080176844A1 (en) 2008-07-24
MX2007010144A (es) 2008-02-15
CN102351862A (zh) 2012-02-15
WO2006089276A2 (en) 2006-08-24
UA90502C2 (ru) 2010-05-11
EA018668B1 (ru) 2013-09-30
US20100093719A1 (en) 2010-04-15
JP2008530247A (ja) 2008-08-07
GEP20115184B (en) 2011-03-25
BRPI0608381A2 (pt) 2009-12-29
WO2006089276A3 (en) 2006-12-21
AU2006213985A1 (en) 2006-08-24
CN101223171A (zh) 2008-07-16
EP1850853A2 (en) 2007-11-07
AU2006213985B2 (en) 2011-08-25
CN101223171B (zh) 2011-09-14

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Legal Events

Date Code Title Description
DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS: AMEND THE CO-INVENTOR NAME FROM MICHAEL GORGAN TO MICHAEL GROGAN

PC1 Assignment before grant (sect. 113)

Owner name: SURFACE LOGIX, INC.

Free format text: FORMER APPLICANT(S): KATES, STEVEN; CAMPBELL, STEWART; SCHUELLER, OLIVIER; SWEETNAM, PAUL; DUFFY, DAVID; SURFACE LOGIX, INC.; OSTUNI, EMANUELE; GROGAN, MICHAEL

DA2 Applications for amendment section 104

Free format text: THE NATURE OF THE AMENDMENT IS AS SHOWN IN THE STATEMENT( S) FILED 05 OCT 2011.

DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 05 OCT 2011

MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application