AU2006211485B2 - Bacterial glycolipid activation of CD1d-restricted NKT cells - Google Patents
Bacterial glycolipid activation of CD1d-restricted NKT cells Download PDFInfo
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- A61K35/66—Microorganisms or materials therefrom
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
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- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55588—Adjuvants of undefined constitution
- A61K2039/55594—Adjuvants of undefined constitution from bacteria
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- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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| US7645873B2 (en) | 2003-03-20 | 2010-01-12 | The Scripps Research Institute | 6″-amino-6″-deoxygalactosylceramides |
| SI2056842T1 (sl) * | 2006-04-07 | 2013-02-28 | The Scripps Research Institute | Modificiran galaktosil-ceramid za zdravljenje kancerogenih obolenj |
| AU2007269299B2 (en) | 2006-06-30 | 2013-01-17 | Brigham Young University | Adjuvants and methods of use |
| JP2010523724A (ja) * | 2007-04-13 | 2010-07-15 | アカデミア シニカ | α−ガラクトシルセラミド類似体およびそれらの免疫療法剤としての使用 |
| US8916164B2 (en) | 2007-08-29 | 2014-12-23 | Abivax | Methods of enhancing adjuvaticity of vaccine compositions |
| AU2013202869B2 (en) * | 2007-11-07 | 2015-10-22 | Abivax | Increase of immune response and targeting by antigens and/or drug linkage |
| EP2058011A1 (en) | 2007-11-07 | 2009-05-13 | Wittycell | Nkt cell activating gycolipids covalently bound antigens and/or drug |
| EP2060252A1 (en) | 2007-11-19 | 2009-05-20 | Wittycell | New formulation of galactosylceramide derivatives |
| EP2231145B1 (en) | 2007-12-05 | 2014-09-17 | Wittycell | Use of glycosylceramides for enhancing the immune response to antigens |
| CN102215864A (zh) * | 2008-10-08 | 2011-10-12 | 威蒂赛尔公司 | 用于抗流感的疫苗组合物 |
| CA2753641C (en) | 2009-02-25 | 2014-09-16 | Supratek Pharma, Inc. | Bendamustine cyclopolysaccharide compositions |
| US8383663B2 (en) | 2010-07-19 | 2013-02-26 | Supratek Pharma Inc. | Bendamustine anionic-catioinic cyclopolysaccharide compositions |
| US9764037B2 (en) * | 2012-12-06 | 2017-09-19 | Victoria Link Limited | Conjugate compounds |
| US9580758B2 (en) | 2013-11-12 | 2017-02-28 | Luc Montagnier | System and method for the detection and treatment of infection by a microbial agent associated with HIV infection |
| EP4138849A4 (en) * | 2020-04-23 | 2024-04-17 | The Regents of the University of California | CLEARANCE OF SENESCENT CELLS BY ACTIVATION OF INKT LYMPHOCYTES |
| WO2022129549A1 (en) * | 2020-12-18 | 2022-06-23 | L'oreal | Extract of bacteria of the genus sphingomonas |
| FR3117776B1 (fr) * | 2020-12-18 | 2024-03-08 | Oreal | Extrait de bactérie du genreSphingomonas |
| IL305579A (en) | 2021-03-01 | 2023-10-01 | Deciduous Therapeutics Inc | Compounds for activating invariant natural killer T cells and methods for use in eliminating inflammatory senescent cells |
| WO2024107463A1 (en) * | 2022-11-14 | 2024-05-23 | The Trustees Of Columbia University In The City Of New York | 7dw8-5 treatment for covid-19 and other virus-induced respiratory infections |
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| WO2003018039A1 (en) * | 2001-08-22 | 2003-03-06 | Dna Informatics Inc. | Pharmaceutical ingredient for medical treatment and preventing of cancer |
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| US5936076A (en) | 1991-08-29 | 1999-08-10 | Kirin Beer Kabushiki Kaisha | αgalactosylceramide derivatives |
| TW261533B (enExample) | 1992-07-16 | 1995-11-01 | Kirin Brewery | |
| CA2147629C (en) | 1992-10-22 | 2005-03-22 | Koji Akimoto | Novel sphingoglycolipids and the use thereof |
| AU683653B2 (en) | 1993-04-15 | 1997-11-20 | Kirin Pharma Kabushiki Kaisha | Novel sphingoglycolipid and use thereof |
| CA2162478A1 (en) | 1993-05-14 | 1994-11-24 | Shawn A. Defrees | Sialyl lex analogues as inhibitors of cellular adhesion |
| CN1222293C (zh) | 1997-04-10 | 2005-10-12 | 麒麟麦酒株式会社 | 含有α-糖基神经酰胺的NKT细胞活化剂 |
| JP2001515868A (ja) * | 1997-09-12 | 2001-09-25 | ブライハム アンド ウイメンズ ホスピタル | Cd1制限免疫応答のための合成抗原 |
| AU2001252599A1 (en) | 2000-04-28 | 2001-11-12 | Orient Cancer Therapy Co., Ltd. | Remedies for cancer |
| US20020071842A1 (en) * | 2000-06-05 | 2002-06-13 | Gumperz Jenny E. | Soluble CD1 compositions and uses thereof |
| PT1297017E (pt) * | 2000-06-19 | 2012-09-04 | Gen Hospital Corp | Composições e métodos de anticorpos monoclonais e policlonais específicos para subpopulações de célula t |
| WO2001098317A2 (en) * | 2000-06-22 | 2001-12-27 | The Brigham And Women's Hospital, Inc. | Alpha-glycosylceramides for treating bacterial and fungal infections |
| EP1434859A2 (en) | 2001-07-25 | 2004-07-07 | New York University | Use of glycosylceramides as adjuvants for vaccines against infections and cancer |
| CN1578667A (zh) | 2001-11-06 | 2005-02-09 | 东方癌症治疗株式会社 | 抗癌组合物 |
| JP2005533057A (ja) * | 2002-06-13 | 2005-11-04 | ニューヨーク・ユニバーシティ | 合成c−糖脂質、ならびに癌、感染性疾患および自己免疫疾患を処置するための合成c−糖脂質の使用 |
| AU2003225891A1 (en) | 2003-03-20 | 2004-11-19 | Brigham Young University | 6"-amino-6"-deoxygalactosylceramides |
| US7645873B2 (en) | 2003-03-20 | 2010-01-12 | The Scripps Research Institute | 6″-amino-6″-deoxygalactosylceramides |
| GB0314682D0 (en) | 2003-06-24 | 2003-07-30 | Isis Innovation | Materials and methods relating to the modulation of T cell response to soluble antigen |
| US7998739B2 (en) | 2004-09-03 | 2011-08-16 | The Scipps Research Institute | Methods of activating NKT cells |
| SI2056842T1 (sl) | 2006-04-07 | 2013-02-28 | The Scripps Research Institute | Modificiran galaktosil-ceramid za zdravljenje kancerogenih obolenj |
| AU2007269299B2 (en) | 2006-06-30 | 2013-01-17 | Brigham Young University | Adjuvants and methods of use |
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| WO2003018039A1 (en) * | 2001-08-22 | 2003-03-06 | Dna Informatics Inc. | Pharmaceutical ingredient for medical treatment and preventing of cancer |
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| Brutkiewicz, R. R. et al., Critical Reviews in Immunology, 2003, Vol. 23, pages 403-419 * |
| Brutkiewicz, R. R. et al., Critical Reviews in Oncology/Hematology, 2002, Vol. 41, pages 287-298 * |
| Singh, A. K. et al., FASEB Journal, Vol. 16, No. 5, page A1043 * |
| Wu, D. et al., PNAS, 2005, Vol. 102, No. 5, pages 1351-1356 * |
Also Published As
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| DK1848813T3 (da) | 2013-07-15 |
| ES2423005T3 (es) | 2013-09-17 |
| BRPI0607299A2 (pt) | 2009-08-25 |
| EP1848813A2 (en) | 2007-10-31 |
| EP1848813B1 (en) | 2013-04-10 |
| US20080279894A1 (en) | 2008-11-13 |
| JP2008528608A (ja) | 2008-07-31 |
| WO2006083671A2 (en) | 2006-08-10 |
| PL1848813T3 (pl) | 2013-09-30 |
| AU2006211485A1 (en) | 2006-08-10 |
| JP5053101B2 (ja) | 2012-10-17 |
| WO2006083671B1 (en) | 2007-04-12 |
| CA2593715A1 (en) | 2006-08-10 |
| CA2593715C (en) | 2015-05-05 |
| ZA200706208B (en) | 2008-04-30 |
| PT1848813E (pt) | 2013-07-15 |
| EP1848813A4 (en) | 2008-07-09 |
| US9295722B2 (en) | 2016-03-29 |
| WO2006083671A3 (en) | 2007-02-22 |
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