AU2006208043B2 - Thiophene compounds for inflammation and immune-related uses - Google Patents

Thiophene compounds for inflammation and immune-related uses Download PDF

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Publication number
AU2006208043B2
AU2006208043B2 AU2006208043A AU2006208043A AU2006208043B2 AU 2006208043 B2 AU2006208043 B2 AU 2006208043B2 AU 2006208043 A AU2006208043 A AU 2006208043A AU 2006208043 A AU2006208043 A AU 2006208043A AU 2006208043 B2 AU2006208043 B2 AU 2006208043B2
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Australia
Prior art keywords
optionally substituted
methyl
phenyl
thiophen
difluoro
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Ceased
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AU2006208043A
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AU2006208043A1 (en
Inventor
Shoujun Chen
Jun Jiang
Lijun Sun
Zhi-Qiang Xia
Yu Xie
Chih-Yi Yu
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Synta Phamaceuticals Corp
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Synta Phamaceuticals Corp
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    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
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  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
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AU2006208043A 2005-01-25 2006-01-25 Thiophene compounds for inflammation and immune-related uses Ceased AU2006208043B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US64677205P 2005-01-25 2005-01-25
US60/646,772 2005-01-25
PCT/US2006/002872 WO2006081389A1 (en) 2005-01-25 2006-01-25 Thiophene compounds for inflammation and immune-related uses

Publications (2)

Publication Number Publication Date
AU2006208043A1 AU2006208043A1 (en) 2006-08-03
AU2006208043B2 true AU2006208043B2 (en) 2012-09-20

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US (1) US8802721B2 (enExample)
EP (1) EP1846388A4 (enExample)
JP (2) JP5221147B2 (enExample)
AU (1) AU2006208043B2 (enExample)
CA (1) CA2595000C (enExample)
TW (1) TWI444187B (enExample)
WO (1) WO2006081389A1 (enExample)

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CA2640090A1 (en) * 2006-01-25 2007-08-02 Synta Pharmaceuticals Corp. Substituted aromatic compounds for inflammation and immune-related uses
WO2007087443A2 (en) 2006-01-25 2007-08-02 Synta Pharmaceuticals Corp. Vinyl-phenyl derivatives for inflammation and immune-related uses
JP2009528273A (ja) * 2006-01-25 2009-08-06 シンタ ファーマシューティカルズ コーポレーション 炎症および免疫関連使用用の置換ビアリール化合物
CA2645434A1 (en) 2006-03-20 2007-09-27 Synta Pharmaceutical Corp. Benzoimidazolyl-parazine compounds for inflammation and immune-related uses
US8779154B2 (en) * 2006-09-26 2014-07-15 Qinglin Che Fused ring compounds for inflammation and immune-related uses
RU2465272C2 (ru) 2007-09-10 2012-10-27 КалсиМедика, Инк. Соединения, моделирующие внутриклеточный кальций
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US20110052643A1 (en) * 2008-01-07 2011-03-03 Synta Pharmaceuticals Corp. Compounds for inflammation and immune-related uses
CA2734500A1 (en) 2008-08-27 2010-03-11 Calcimedica Inc. Compounds that modulate intracellular calcium
US8524763B2 (en) * 2008-09-22 2013-09-03 Calcimedica, Inc. Inhibitors of store operated calcium release
EP2350064A1 (en) * 2008-10-01 2011-08-03 Synta Pharmaceuticals Corp. Compounds for inflammation and immune-related uses
US8143269B2 (en) 2008-10-03 2012-03-27 Calcimedica, Inc. Inhibitors of store operated calcium release
US8399436B2 (en) * 2009-04-24 2013-03-19 Glaxo Group Limited N-pyrazolyl carboxamides as CRAC channel inhibitors
WO2010122088A1 (en) * 2009-04-24 2010-10-28 Glaxo Group Limited Pyrazole and triazole carboxamides as crac channel inhibitors
MX2012002591A (es) 2009-09-03 2012-04-02 Allergan Inc Compuestos como moduladores de tirosina cinasas.
US9340555B2 (en) 2009-09-03 2016-05-17 Allergan, Inc. Compounds as tyrosine kinase modulators
US8618307B2 (en) * 2009-09-16 2013-12-31 Calcimedica, Inc. Compounds that modulate intracellular calcium
US8377970B2 (en) 2009-10-08 2013-02-19 Rhizen Pharmaceuticals Sa Modulators of calcium release-activated calcium channel
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