AU2005332996A1 - Antagonizing interleukin-21 receptor activity - Google Patents

Antagonizing interleukin-21 receptor activity Download PDF

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Publication number
AU2005332996A1
AU2005332996A1 AU2005332996A AU2005332996A AU2005332996A1 AU 2005332996 A1 AU2005332996 A1 AU 2005332996A1 AU 2005332996 A AU2005332996 A AU 2005332996A AU 2005332996 A AU2005332996 A AU 2005332996A AU 2005332996 A1 AU2005332996 A1 AU 2005332996A1
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Australia
Prior art keywords
antibody
seq
disorder
fragment
human
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Abandoned
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AU2005332996A
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English (en)
Inventor
Mary Collins
Kyriaki Dunussi-Joannopoulos
Marion T. Kasaian
Richard Michael O'Hara Jr.
Matthew J. Whitters
Deborah A. Young
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Wyeth LLC
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Wyeth LLC
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • A01K67/0275Genetically modified vertebrates, e.g. transgenic
    • A01K67/0276Knock-out vertebrates
    • AHUMAN NECESSITIES
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    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1793Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K49/00Preparations for testing in vivo
    • A61K49/0004Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A61K49/0008Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts, e.g. Alzheimer disease animal model, transgenic model for heart failure
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    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
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    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869Interleukin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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AU2005332996A 2004-08-05 2005-08-05 Antagonizing interleukin-21 receptor activity Abandoned AU2005332996A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US59908604P 2004-08-05 2004-08-05
US60/599,086 2004-08-05
US63917604P 2004-12-23 2004-12-23
US60/639,176 2004-12-23
PCT/US2005/027912 WO2006135385A2 (en) 2004-08-05 2005-08-05 Antagonizing interleukin-21 receptor activity

Publications (1)

Publication Number Publication Date
AU2005332996A1 true AU2005332996A1 (en) 2006-12-21

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AU2005332996A Abandoned AU2005332996A1 (en) 2004-08-05 2005-08-05 Antagonizing interleukin-21 receptor activity

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US (2) US20060039902A1 (enExample)
EP (1) EP1773394A2 (enExample)
JP (1) JP2008508885A (enExample)
KR (1) KR20070057789A (enExample)
AR (1) AR051071A1 (enExample)
AU (1) AU2005332996A1 (enExample)
BR (1) BRPI0514138A (enExample)
CA (1) CA2574848A1 (enExample)
CR (1) CR8891A (enExample)
EC (1) ECSP077226A (enExample)
IL (1) IL181044A0 (enExample)
MX (1) MX2007001509A (enExample)
NO (1) NO20070973L (enExample)
RU (1) RU2007102287A (enExample)
TW (1) TW200608995A (enExample)
WO (1) WO2006135385A2 (enExample)

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