AU2005251573B2 - Use of 7-t-butoxyiminomethylcamptothecin for treating uterine neoplasms - Google Patents

Use of 7-t-butoxyiminomethylcamptothecin for treating uterine neoplasms Download PDF

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Publication number
AU2005251573B2
AU2005251573B2 AU2005251573A AU2005251573A AU2005251573B2 AU 2005251573 B2 AU2005251573 B2 AU 2005251573B2 AU 2005251573 A AU2005251573 A AU 2005251573A AU 2005251573 A AU2005251573 A AU 2005251573A AU 2005251573 B2 AU2005251573 B2 AU 2005251573B2
Authority
AU
Australia
Prior art keywords
butoxyiminomethylcamptothecin
neoplasm
medicament
cancer
use according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2005251573A
Other languages
English (en)
Other versions
AU2005251573A1 (en
Inventor
Paolo Carminati
Franco Cavalli
Marco Corsi
Luca Gianni
Cristiana Sessa
Claudio Zanna
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sigma Tau Industrie Farmaceutiche Riunite SpA
Original Assignee
Sigma Tau Industrie Farmaceutiche Riunite SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Industrie Farmaceutiche Riunite SpA filed Critical Sigma Tau Industrie Farmaceutiche Riunite SpA
Publication of AU2005251573A1 publication Critical patent/AU2005251573A1/en
Application granted granted Critical
Publication of AU2005251573B2 publication Critical patent/AU2005251573B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4741—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having oxygen as a ring hetero atom, e.g. tubocuraran derivatives, noscapine, bicuculline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU2005251573A 2004-06-11 2005-06-08 Use of 7-t-butoxyiminomethylcamptothecin for treating uterine neoplasms Ceased AU2005251573B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITRM2004A000288 2004-06-11
IT000288A ITRM20040288A1 (it) 2004-06-11 2004-06-11 Uso della 7-t-butossiimminometilcamptotecina per la preparazione di un medicamento per il trattamento delle neoplasie dell'utero.
PCT/IT2005/000320 WO2005120643A2 (en) 2004-06-11 2005-06-08 Use of 7-t-butoxyiminomethylcamptothecin for treating uterine neoplasms

Publications (2)

Publication Number Publication Date
AU2005251573A1 AU2005251573A1 (en) 2005-12-22
AU2005251573B2 true AU2005251573B2 (en) 2010-04-15

Family

ID=34979678

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2005251573A Ceased AU2005251573B2 (en) 2004-06-11 2005-06-08 Use of 7-t-butoxyiminomethylcamptothecin for treating uterine neoplasms

Country Status (23)

Country Link
US (1) US7700613B2 (enExample)
EP (1) EP1773451B1 (enExample)
JP (2) JP2008501785A (enExample)
KR (1) KR101221640B1 (enExample)
CN (2) CN1953784A (enExample)
AR (1) AR049220A1 (enExample)
AT (1) ATE521351T1 (enExample)
AU (1) AU2005251573B2 (enExample)
BR (1) BRPI0511931A (enExample)
CA (1) CA2565213C (enExample)
CY (1) CY1112032T1 (enExample)
DK (1) DK1773451T3 (enExample)
ES (1) ES2372056T3 (enExample)
HK (1) HK1205951A1 (enExample)
HR (1) HRP20110718T1 (enExample)
IT (1) ITRM20040288A1 (enExample)
MX (1) MXPA06014162A (enExample)
PL (1) PL1773451T3 (enExample)
PT (1) PT1773451E (enExample)
RS (1) RS52038B (enExample)
SI (1) SI1773451T1 (enExample)
TW (1) TWI351283B (enExample)
WO (1) WO2005120643A2 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080213385A1 (en) * 2005-08-10 2008-09-04 Oskar Kalb Formulations for 7- (T-Butoxy) Iminomethyl Camptothecin
AU2008210511A1 (en) * 2007-02-01 2008-08-07 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Pharmaceutical composition comprising a campothecin derivative

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000053607A1 (en) * 1999-03-09 2000-09-14 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Camptothecin derivatives having antitumor activity
WO2003043584A2 (en) * 2001-11-20 2003-05-30 University Of Kentucky Research Foundation Engineered liposomal particles containing core-loaded pro-drugs for the controlled release of camptothecins
AU2004241729A1 (en) * 2003-05-21 2004-12-02 Novartis Ag Combination of histone deacetylase inhibitors with chemotherapeutic agents

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2757514B1 (fr) * 1996-12-20 1999-02-12 Sod Conseils Rech Applic Nouveaux analogues de la camptothecine, des procedes de preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant
DE69635560T2 (de) * 1995-06-21 2006-08-17 Société de Conseils de Recherches et D'Applications Scientifiques (S.C.R.A.S.) Camptothecinanaloge, Verfahren zur ihrer Herstellung, ihre Verwendung als Arzneimittel und diese enthaltende pharmazeutische Zusammensetzungen
UA57757C2 (uk) * 1996-12-20 2003-07-15 Сос'Єте Де Консей Де Решерш Е Даплікасьон С'Єнтіфік (С.К.Р.А.С.) Аналоги камптотецину, спосіб їх отримання (варіанти) і фармацевтична композиція
US7105492B2 (en) * 1999-03-09 2006-09-12 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Camptothecin derivatives having antitumor activity
IT1306129B1 (it) * 1999-04-13 2001-05-30 Sigma Tau Ind Farmaceuti Esteri della l-carnitina o di alcanoil l-carnitine utilizzabili comelipidi cationici per l'immissione intracellulare di composti
US6352996B1 (en) * 1999-08-03 2002-03-05 The Stehlin Foundation For Cancer Research Liposomal prodrugs comprising derivatives of camptothecin and methods of treating cancer using these prodrugs

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000053607A1 (en) * 1999-03-09 2000-09-14 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Camptothecin derivatives having antitumor activity
WO2003043584A2 (en) * 2001-11-20 2003-05-30 University Of Kentucky Research Foundation Engineered liposomal particles containing core-loaded pro-drugs for the controlled release of camptothecins
AU2004241729A1 (en) * 2003-05-21 2004-12-02 Novartis Ag Combination of histone deacetylase inhibitors with chemotherapeutic agents

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
De Cesare et al (2001) Cancer Research, 1 October, 61:7189-7195 *
Kavanagh et al (1998) Oncology, 1 August, 12(8 Suppl 6):94-98 *
Rothenberg (1996) Seminars in Oncology, February, 23(1 Suppl 3):21-26 *

Also Published As

Publication number Publication date
TWI351283B (en) 2011-11-01
CN1953784A (zh) 2007-04-25
SI1773451T1 (sl) 2012-01-31
JP2008501785A (ja) 2008-01-24
ES2372056T3 (es) 2012-01-13
WO2005120643A8 (en) 2006-12-14
BRPI0511931A (pt) 2008-01-22
CA2565213C (en) 2012-08-07
CA2565213A1 (en) 2005-12-22
CY1112032T1 (el) 2015-11-04
ITRM20040288A1 (it) 2004-09-11
PT1773451E (pt) 2011-11-02
JP2014231518A (ja) 2014-12-11
AR049220A1 (es) 2006-07-05
WO2005120643A3 (en) 2006-03-30
CN104352496A (zh) 2015-02-18
AU2005251573A1 (en) 2005-12-22
US7700613B2 (en) 2010-04-20
DK1773451T3 (da) 2011-11-28
KR101221640B1 (ko) 2013-01-14
WO2005120643A2 (en) 2005-12-22
MXPA06014162A (es) 2007-03-07
EP1773451A2 (en) 2007-04-18
EP1773451B1 (en) 2011-08-24
US20080020030A1 (en) 2008-01-24
RS52038B (sr) 2012-04-30
HRP20110718T1 (hr) 2011-12-31
KR20070030246A (ko) 2007-03-15
TW200605891A (en) 2006-02-16
ATE521351T1 (de) 2011-09-15
HK1205951A1 (en) 2015-12-31
PL1773451T3 (pl) 2012-01-31

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FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired