AU2005240849B2 - Ester linked macrolides useful for the treatment of microbial infections - Google Patents

Ester linked macrolides useful for the treatment of microbial infections Download PDF

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Publication number
AU2005240849B2
AU2005240849B2 AU2005240849A AU2005240849A AU2005240849B2 AU 2005240849 B2 AU2005240849 B2 AU 2005240849B2 AU 2005240849 A AU2005240849 A AU 2005240849A AU 2005240849 A AU2005240849 A AU 2005240849A AU 2005240849 B2 AU2005240849 B2 AU 2005240849B2
Authority
AU
Australia
Prior art keywords
ethoxy
oxo
dihydro
carboxy
propionyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2005240849A
Other languages
English (en)
Other versions
AU2005240849A1 (en
Inventor
Sulejman Alihodzic
Samra Kapic
Maja Matanovic
Stjepan Mutak
Ivana Palej
Drazen Pavlovic
Vlado Stimac
Adrijana Zupan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fidelta doo
Original Assignee
GlaxoSmithKline Istrazivacki Centar Zagreb doo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GlaxoSmithKline Istrazivacki Centar Zagreb doo filed Critical GlaxoSmithKline Istrazivacki Centar Zagreb doo
Publication of AU2005240849A1 publication Critical patent/AU2005240849A1/en
Application granted granted Critical
Publication of AU2005240849B2 publication Critical patent/AU2005240849B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AU2005240849A 2004-05-06 2005-05-02 Ester linked macrolides useful for the treatment of microbial infections Ceased AU2005240849B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US56940204P 2004-05-06 2004-05-06
US60/569,402 2004-05-06
US58111804P 2004-06-18 2004-06-18
US60/581,118 2004-06-18
PCT/IB2005/001186 WO2005108412A1 (en) 2004-05-06 2005-05-02 Ester linked macrolides useful for the treatment of microbial infections

Publications (2)

Publication Number Publication Date
AU2005240849A1 AU2005240849A1 (en) 2005-11-17
AU2005240849B2 true AU2005240849B2 (en) 2008-10-23

Family

ID=34967616

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2005240849A Ceased AU2005240849B2 (en) 2004-05-06 2005-05-02 Ester linked macrolides useful for the treatment of microbial infections

Country Status (16)

Country Link
US (1) US20080255060A1 (enExample)
EP (1) EP1756135B1 (enExample)
JP (1) JP2007536371A (enExample)
AR (1) AR049269A1 (enExample)
AT (1) ATE439367T1 (enExample)
AU (1) AU2005240849B2 (enExample)
BR (1) BRPI0510328A (enExample)
CA (1) CA2566085A1 (enExample)
DE (1) DE602005015963D1 (enExample)
ES (1) ES2331739T3 (enExample)
IL (1) IL178876A0 (enExample)
MA (1) MA28640B1 (enExample)
MX (1) MXPA06012923A (enExample)
NO (1) NO20065662L (enExample)
RU (1) RU2006143051A (enExample)
WO (1) WO2005108412A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1638549A4 (en) 2003-03-10 2011-06-15 Optimer Pharmaceuticals Inc NEW ANTIBACTERIAL AGENTS
EP1879903A1 (en) 2005-05-10 2008-01-23 GlaxoSmithKline istrazivacki centar Zagreb d.o.o. Ether linked macrolides useful for the treatment of microbial infections
AU2007330456B2 (en) * 2006-12-05 2011-03-03 Pfizer Inc. Motilide polymorphs
US9453042B2 (en) 2007-10-25 2016-09-27 Cempra Pharmaceuticals, Inc. Process for the preparation of macrolide antibacterial agents
HRP20160222T1 (hr) 2008-10-24 2016-04-08 Cempra Pharmaceuticals, Inc. Biozaštite uporabom makrolida koji sadrže triazol
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
EP2475253B1 (en) 2009-09-10 2016-10-26 Cempra Pharmaceuticals, Inc. Methods for treating malaria, tuberculosis and mac diseases
CN102917708B (zh) 2010-05-20 2015-11-25 森普拉制药公司 制备大环内酯和酮内酯及其中间体的方法
US9815863B2 (en) 2010-09-10 2017-11-14 Cempra Pharmaceuticals, Inc. Hydrogen bond forming fluoro ketolides for treating diseases
IN2014DN08939A (enExample) 2012-03-27 2015-05-22 Cempra Pharmaceuticals Inc
CA2905975A1 (en) 2013-03-14 2014-09-25 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
EP2968384A4 (en) 2013-03-15 2017-02-15 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents
GB201608236D0 (en) 2016-05-11 2016-06-22 Fidelta D O O Seco macrolide compounds

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003042228A1 (en) * 2001-11-14 2003-05-22 Glaxo Group Limited Macrolides
WO2004101585A1 (en) * 2003-05-13 2004-11-25 Glaxo Group Limited Macrolides substituded at the 4'-position

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0225384D0 (en) * 2002-10-31 2002-12-11 Glaxo Group Ltd Novel compounds
GB0310979D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
HRP20070094T3 (hr) * 2003-05-13 2008-05-31 Glaxo Group Limited NOVI 14- i 15-EROČLANI PRSTENASTI SPOJEVI
EP1879903A1 (en) * 2005-05-10 2008-01-23 GlaxoSmithKline istrazivacki centar Zagreb d.o.o. Ether linked macrolides useful for the treatment of microbial infections

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003042228A1 (en) * 2001-11-14 2003-05-22 Glaxo Group Limited Macrolides
WO2004101585A1 (en) * 2003-05-13 2004-11-25 Glaxo Group Limited Macrolides substituded at the 4'-position

Also Published As

Publication number Publication date
AU2005240849A1 (en) 2005-11-17
ES2331739T3 (es) 2010-01-14
IL178876A0 (en) 2007-03-08
DE602005015963D1 (de) 2009-09-24
AR049269A1 (es) 2006-07-12
NO20065662L (no) 2007-01-16
RU2006143051A (ru) 2008-06-20
JP2007536371A (ja) 2007-12-13
US20080255060A1 (en) 2008-10-16
WO2005108412A1 (en) 2005-11-17
MXPA06012923A (es) 2007-07-18
CA2566085A1 (en) 2005-11-17
EP1756135A1 (en) 2007-02-28
MA28640B1 (fr) 2007-06-01
ATE439367T1 (de) 2009-08-15
EP1756135B1 (en) 2009-08-12
BRPI0510328A (pt) 2007-10-23

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired