AU2005238486A1 - Method and device for sample preparation control - Google Patents
Method and device for sample preparation control Download PDFInfo
- Publication number
- AU2005238486A1 AU2005238486A1 AU2005238486A AU2005238486A AU2005238486A1 AU 2005238486 A1 AU2005238486 A1 AU 2005238486A1 AU 2005238486 A AU2005238486 A AU 2005238486A AU 2005238486 A AU2005238486 A AU 2005238486A AU 2005238486 A1 AU2005238486 A1 AU 2005238486A1
- Authority
- AU
- Australia
- Prior art keywords
- sample
- sample preparation
- nucleic acid
- chamber
- preparation controls
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- 238000000034 method Methods 0.000 title claims description 65
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- ZJYYHGLJYGJLLN-UHFFFAOYSA-N guanidinium thiocyanate Chemical compound SC#N.NC(N)=N ZJYYHGLJYGJLLN-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0681—Filter
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0478—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure pistons
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0622—Valves, specific forms thereof distribution valves, valves having multiple inlets and/or outlets, e.g. metering valves, multi-way valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0633—Valves, specific forms thereof with moving parts
- B01L2400/0644—Valves, specific forms thereof with moving parts rotary valves
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
- G01N2001/2866—Grinding or homogeneising
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00594—Quality control, including calibration or testing of components of the analyser
- G01N35/00693—Calibration
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Clinical Laboratory Science (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- General Physics & Mathematics (AREA)
- Quality & Reliability (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/834,538 US20050244837A1 (en) | 2004-04-28 | 2004-04-28 | Method and device for sample preparation control |
| US10/834,538 | 2004-04-28 | ||
| PCT/US2005/013897 WO2005106040A2 (en) | 2004-04-28 | 2005-04-22 | Method and device for sample preparation control |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2005238486A1 true AU2005238486A1 (en) | 2005-11-10 |
Family
ID=35187542
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2005238486A Abandoned AU2005238486A1 (en) | 2004-04-28 | 2005-04-22 | Method and device for sample preparation control |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20050244837A1 (enExample) |
| EP (1) | EP1740720A4 (enExample) |
| JP (1) | JP2007535323A (enExample) |
| KR (1) | KR20070011525A (enExample) |
| CN (1) | CN101124334A (enExample) |
| AU (1) | AU2005238486A1 (enExample) |
| CA (1) | CA2564620A1 (enExample) |
| WO (1) | WO2005106040A2 (enExample) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7569342B2 (en) | 1997-12-10 | 2009-08-04 | Sierra Molecular Corp. | Removal of molecular assay interferences |
| WO2006039293A2 (en) * | 2004-09-29 | 2006-04-13 | University Of Virginia Patent Foundation | Localized control of thermal properties on microdevices and applications thereof |
| WO2006044458A2 (en) | 2004-10-13 | 2006-04-27 | University Of Virginia Patent Foundation | Electrostatic actuation for management of flow |
| US20080277387A1 (en) * | 2004-12-22 | 2008-11-13 | Landers James P | Use of Microwaves For Thermal and Non-Thermal Applications in Micro and Nanoscale Devices |
| WO2007030240A2 (en) * | 2005-08-01 | 2007-03-15 | University Of Virginia Patent Foundation | Microdevices for chemical sensing and chemical actuation |
| US8220493B2 (en) * | 2005-08-23 | 2012-07-17 | University Of Virginia Patent Foundation | Passive components for micro-fluidic flow profile shaping and related method thereof |
| CA2624914A1 (en) * | 2005-10-04 | 2007-04-12 | University Of Virginia Patent Foundation | Microchip-based acoustic trapping or capture of cells for forensic analysis and related method thereof |
| US8916375B2 (en) * | 2005-10-12 | 2014-12-23 | University Of Virginia Patent Foundation | Integrated microfluidic analysis systems |
| US8372340B2 (en) | 2005-10-19 | 2013-02-12 | Luminex Corporation | Apparatus and methods for integrated sample preparation, reaction and detection |
| US7754148B2 (en) | 2006-12-27 | 2010-07-13 | Progentech Limited | Instrument for cassette for sample preparation |
| US7727473B2 (en) | 2005-10-19 | 2010-06-01 | Progentech Limited | Cassette for sample preparation |
| WO2008012550A2 (en) | 2006-07-28 | 2008-01-31 | Diagnostics For The Real World, Ltd. | Device, system and method for processing a sample |
| GB0704035D0 (en) | 2007-03-02 | 2007-04-11 | Smiths Detection Watford Ltd | Sample preparation apparatus |
| JP5547071B2 (ja) * | 2007-08-09 | 2014-07-09 | セルラ・インコーポレイテッド | 関連付け多パラメーター単一細胞測定および残留する生物学的材料の回収のための方法および装置 |
| WO2009024773A1 (en) | 2007-08-17 | 2009-02-26 | Diagnostics For The Real World, Ltd | Device, system and method for processing a sample |
| ES2744553T3 (es) * | 2008-04-10 | 2020-02-25 | Denator Ab | Dispositivo de almacenamiento de una muestra biológica y de preparación de la muestra biológica |
| EP2143491A1 (en) * | 2008-07-10 | 2010-01-13 | Carpegen GmbH | Device for analysing a chemical or biological sample |
| JP2013507943A (ja) * | 2009-10-21 | 2013-03-07 | リボックス・ゲーエムベーハー | Ｒｎａの指数関数的増幅のための方法およびｒｎａリアクター |
| ES2653916T3 (es) | 2011-03-08 | 2018-02-09 | Universite Laval | Dispositivo centrípeto fluídico |
| EP2705130B1 (en) | 2011-05-04 | 2016-07-06 | Luminex Corporation | Apparatus and methods for integrated sample preparation, reaction and detection |
| KR101481054B1 (ko) * | 2011-11-15 | 2015-01-14 | 한국기계연구원 | 핵산 자동 분석 장치 |
| US10132728B2 (en) | 2012-04-27 | 2018-11-20 | Cepheid | Apparatus with heterogeneous processing modules |
| FR2993281B1 (fr) * | 2012-07-13 | 2014-07-18 | Biomerieux Sa | Systeme automatise de lyse de microorganismes presents dans un echantillon, d'extraction et de purification des acides nucleiques desdits microorganismes aux fins d'analyse |
| US9987576B2 (en) | 2012-12-10 | 2018-06-05 | University Of Virginia Patent Foundation | Frequency-based filtering of mechanical actuation using fluidic device |
| CZ304743B6 (cs) * | 2013-01-18 | 2014-09-17 | Wolf & Danniel S.R.O. | Prostředek pro izolaci nukleových kyselin a způsob prováděný pomocí tohoto prostředku |
| CN103954783B (zh) * | 2014-04-14 | 2015-07-22 | 珠海森龙生物科技有限公司 | 一次性大便反应杯 |
| EP3009679A1 (en) | 2014-10-14 | 2016-04-20 | Carpegen GmbH | Hose pump and device for analysing a chemical or biological sample |
| CN104673625B (zh) * | 2015-02-13 | 2017-02-08 | 西安交通大学 | 一种对细胞进行预处理的自动反应装置及方法 |
| USD799715S1 (en) | 2015-10-23 | 2017-10-10 | Gene POC, Inc. | Fluidic centripetal device |
| CN109982778A (zh) * | 2016-09-23 | 2019-07-05 | 阿谢尔德克斯有限公司 | 流体系统及相关方法 |
| CN110998333B (zh) * | 2017-05-16 | 2023-08-25 | Sk电信有限公司 | 使用盒的核酸分析设备 |
| KR102076220B1 (ko) * | 2017-12-28 | 2020-02-11 | 에스디 바이오센서 주식회사 | 핵산 추출용 카트리지의 유로 구조 |
| KR102065650B1 (ko) * | 2017-12-28 | 2020-02-11 | 에스디 바이오센서 주식회사 | 카트리지를 이용한 핵산 추출 방법 |
| KR102065649B1 (ko) * | 2017-12-28 | 2020-01-13 | 에스디 바이오센서 주식회사 | 핵산 추출용 카트리지의 피스톤 |
| US10527192B2 (en) | 2018-02-15 | 2020-01-07 | Talis Biomedical Corporation | Rotary valve |
| CN108828221B (zh) * | 2018-04-04 | 2019-11-12 | 美林美邦（厦门）生物科技有限公司 | 一种设置有物料转移结构的样本处理及检测试剂杯盒 |
| CN112955258A (zh) * | 2018-10-05 | 2021-06-11 | 多茨技术公司 | 用于过敏原检测的系统和方法 |
| US11008627B2 (en) | 2019-08-15 | 2021-05-18 | Talis Biomedical Corporation | Diagnostic system |
| US11254979B2 (en) | 2020-06-01 | 2022-02-22 | Shaheen Innovations Holding Limited | Systems and devices for infectious disease screening |
| US11730193B2 (en) | 2019-12-15 | 2023-08-22 | Shaheen Innovations Holding Limited | Hookah device |
| CN111190021B (zh) * | 2020-02-22 | 2023-08-11 | 武汉泰沃科技有限责任公司 | 一种生物样品处理盒 |
| CN111394243B (zh) * | 2020-04-27 | 2024-11-12 | 深圳博识诊断技术有限公司 | 微流控芯片核酸检测装置 |
| IL298682B1 (en) * | 2020-06-01 | 2025-10-01 | Shaheen Innovations Holding Ltd | Infectious disease scanning device |
| KR20230034986A (ko) * | 2020-06-01 | 2023-03-10 | 샤힌 이노베이션즈 홀딩 리미티드 | 감염증 스크리닝 시스템 |
| EP3919176A1 (en) * | 2020-06-01 | 2021-12-08 | Shaheen Innovations Holding Limited | Assay devices for infectious disease screening |
| EP3919175A1 (en) * | 2020-06-01 | 2021-12-08 | Shaheen Innovations Holding Limited | Systems and devices for infectious disease screening |
| CN112266856A (zh) * | 2020-10-20 | 2021-01-26 | 广州源创生物科技有限公司 | 微量流体控制机构、核酸检测装置以及免疫检测装置 |
| CA3197077A1 (en) | 2020-10-30 | 2022-05-05 | Ronald Chang | Diagnostic assay system with replaceable processing modules and remote monitoring |
| CN112779157B (zh) * | 2021-01-08 | 2022-06-21 | 鲲鹏基因（北京）科技有限责任公司 | 具备样品制备功能的pcr反应装置 |
| KR102293717B1 (ko) * | 2021-06-29 | 2021-08-26 | 에스디바이오센서 주식회사 | 플로우 커버를 포함하는 유전체 추출 장치 |
| KR102362853B1 (ko) | 2021-08-13 | 2022-02-15 | 에스디바이오센서 주식회사 | 내측 챔버와 결합되는 안전 클립을 포함하는 유전체 추출 장치 |
| CN114739996B (zh) * | 2022-03-02 | 2024-08-13 | 利民(番禺南沙)电器发展有限公司 | 一种一次性使用的病毒检测装置 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0001137A1 (fr) * | 1977-08-31 | 1979-03-21 | S.A. Anarec | Appareil pour le traitement de fluides |
| JPS5847164U (ja) * | 1981-09-22 | 1983-03-30 | 東亜医用電子株式会社 | 自動希釈装置 |
| DE4420732A1 (de) * | 1994-06-15 | 1995-12-21 | Boehringer Mannheim Gmbh | Vorrichtung zur Behandlung von Nukleinsäuren aus einer Probe |
| DE19546952C2 (de) * | 1994-12-17 | 1999-06-17 | Horiba Ltd | Gasanalysator-Einschubanordnung |
| US6168948B1 (en) * | 1995-06-29 | 2001-01-02 | Affymetrix, Inc. | Miniaturized genetic analysis systems and methods |
| US5882903A (en) * | 1996-11-01 | 1999-03-16 | Sarnoff Corporation | Assay system and method for conducting assays |
| EP1179585B1 (en) * | 1997-12-24 | 2008-07-09 | Cepheid | Device and method for lysis |
| US6369893B1 (en) * | 1998-05-19 | 2002-04-09 | Cepheid | Multi-channel optical detection system |
| WO1999047255A1 (en) * | 1998-03-17 | 1999-09-23 | Cepheid | Unitary chemical processing device |
| GB9819418D0 (en) * | 1998-09-07 | 1998-10-28 | Secr Defence | Amplification method |
| US6100084A (en) * | 1998-11-05 | 2000-08-08 | The Regents Of The University Of California | Micro-sonicator for spore lysis |
| US6431476B1 (en) * | 1999-12-21 | 2002-08-13 | Cepheid | Apparatus and method for rapid ultrasonic disruption of cells or viruses |
| US6322980B1 (en) * | 1999-04-30 | 2001-11-27 | Aclara Biosciences, Inc. | Single nucleotide detection using degradation of a fluorescent sequence |
| EP1208189B1 (en) * | 1999-05-28 | 2004-10-06 | Cepheid | Device and method for analysing liquid samples |
| US6664104B2 (en) * | 1999-06-25 | 2003-12-16 | Cepheid | Device incorporating a microfluidic chip for separating analyte from a sample |
| US6358679B1 (en) * | 2000-08-24 | 2002-03-19 | Pe Corporation (Ny) | Methods for external controls for nucleic acid amplification |
| US6374684B1 (en) * | 2000-08-25 | 2002-04-23 | Cepheid | Fluid control and processing system |
| WO2003068918A2 (en) * | 2002-02-11 | 2003-08-21 | Auburn University | High-sensitivity real-time polymerase chain reaction for detection of nucleic acids |
-
2004
- 2004-04-28 US US10/834,538 patent/US20050244837A1/en not_active Abandoned
-
2005
- 2005-04-22 JP JP2007510834A patent/JP2007535323A/ja active Pending
- 2005-04-22 CN CNA200580013828XA patent/CN101124334A/zh active Pending
- 2005-04-22 CA CA002564620A patent/CA2564620A1/en not_active Abandoned
- 2005-04-22 AU AU2005238486A patent/AU2005238486A1/en not_active Abandoned
- 2005-04-22 KR KR1020067024271A patent/KR20070011525A/ko not_active Withdrawn
- 2005-04-22 WO PCT/US2005/013897 patent/WO2005106040A2/en not_active Ceased
- 2005-04-22 EP EP05738740A patent/EP1740720A4/en not_active Withdrawn
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2010
- 2010-01-26 US US12/694,165 patent/US20100129827A1/en not_active Abandoned
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|---|---|
| CA2564620A1 (en) | 2005-11-10 |
| KR20070011525A (ko) | 2007-01-24 |
| WO2005106040A2 (en) | 2005-11-10 |
| US20050244837A1 (en) | 2005-11-03 |
| CN101124334A (zh) | 2008-02-13 |
| EP1740720A4 (en) | 2009-12-02 |
| WO2005106040A3 (en) | 2007-05-03 |
| JP2007535323A (ja) | 2007-12-06 |
| US20100129827A1 (en) | 2010-05-27 |
| EP1740720A2 (en) | 2007-01-10 |
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