AU2004295206A1 - Jasmonate derivative compounds, pharmaceuticals compositions and methods of use thereof - Google Patents

Jasmonate derivative compounds, pharmaceuticals compositions and methods of use thereof Download PDF

Info

Publication number
AU2004295206A1
AU2004295206A1 AU2004295206A AU2004295206A AU2004295206A1 AU 2004295206 A1 AU2004295206 A1 AU 2004295206A1 AU 2004295206 A AU2004295206 A AU 2004295206A AU 2004295206 A AU2004295206 A AU 2004295206A AU 2004295206 A1 AU2004295206 A1 AU 2004295206A1
Authority
AU
Australia
Prior art keywords
cancer
carcinoma
compound
leukemia
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2004295206A
Other languages
English (en)
Inventor
Eliezer Flescher
Yoel Kashman
Dorit Reischer
Shiri Shimony
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ramot at Tel Aviv University Ltd
Original Assignee
Ramot at Tel Aviv University Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ramot at Tel Aviv University Ltd filed Critical Ramot at Tel Aviv University Ltd
Publication of AU2004295206A1 publication Critical patent/AU2004295206A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/716—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU2004295206A 2003-12-02 2004-12-01 Jasmonate derivative compounds, pharmaceuticals compositions and methods of use thereof Abandoned AU2004295206A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US52608103P 2003-12-02 2003-12-02
US60/526,081 2003-12-02
PCT/IL2004/001098 WO2005054172A2 (en) 2003-12-02 2004-12-01 Jasmonate derivative compounds, pharmaceuticals compositions and methods of use thereof

Publications (1)

Publication Number Publication Date
AU2004295206A1 true AU2004295206A1 (en) 2005-06-16

Family

ID=34652413

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2004295206A Abandoned AU2004295206A1 (en) 2003-12-02 2004-12-01 Jasmonate derivative compounds, pharmaceuticals compositions and methods of use thereof

Country Status (7)

Country Link
US (2) US7425651B2 (https=)
EP (1) EP1689696A2 (https=)
JP (1) JP2007514663A (https=)
CN (1) CN1902156A (https=)
AU (1) AU2004295206A1 (https=)
CA (1) CA2548173A1 (https=)
WO (1) WO2005054172A2 (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005054172A2 (en) * 2003-12-02 2005-06-16 Ramot At Tel-Aviv University Ltd. Jasmonate derivative compounds, pharmaceuticals compositions and methods of use thereof
CA2630666A1 (en) 2005-12-07 2007-06-14 Sepal Pharma Ltd. Jasmonate derivatives, pharmaceutical compositions and methods of use thereof
US20090291904A1 (en) * 2005-12-07 2009-11-26 Yoel Kashman Chemical derivatives of jasmonate, pharmaceutical compositions and methods of use thereof
US9284274B2 (en) 2005-12-07 2016-03-15 Ramot At Tel-Aviv University Ltd. Chemical derivatives of jasmonate, pharmaceutical compositions and methods of use thereof
CA2657375A1 (en) * 2006-07-10 2008-01-17 Ramot At Tel-Aviv University Ltd. Combination methods of treating cancer
WO2008111088A2 (en) 2007-03-15 2008-09-18 Ramot At Tel-Aviv University Ltd. Jasmonate based assays for identifying compounds that selectively inhibit mitochondrial bound hexokinases
US9284252B2 (en) 2009-06-09 2016-03-15 Sepal Pharma Ltd. Use of jasmonate ester derivatives for treating benign hyperproliferative skin disorders
CN103140223A (zh) * 2010-05-19 2013-06-05 布罗迪健康科学有限公司 茉莉酮酸酯用于治疗心力衰竭及相关心脏病症的用途
RU2623878C2 (ru) 2010-12-10 2017-06-29 Броади Хэлс Сайенсис, Эл Эл Си Применение жасмоната для лечения нарушения функции мочевого пузыря
WO2013040556A1 (en) 2011-09-16 2013-03-21 Nanocare Technologies, Inc. Compositions of jasmonate compounds and methods of use
CA2971870A1 (en) 2014-12-31 2016-07-07 Nanocare Technologies, Inc. Jasmonate derivatives and compositions thereof
WO2017168416A1 (en) 2016-03-28 2017-10-05 Vidac Pharma Ltd. Stable pharmaceutical compositions for topical administration and uses thereof
US11266639B2 (en) 2016-11-07 2022-03-08 Vidac Pharma Ltd. Use of hexokinase 2/mitochondria-detaching compounds for treating hexokinase-2 (HK2)-expressing cancers
WO2018083704A1 (en) 2016-11-07 2018-05-11 Vidac Pharma Ltd. Use of hexokinase 2/mitochondria-detaching compounds for activating immune responses

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0441414A (ja) * 1990-06-04 1992-02-12 Fujisawa Pharmaceut Co Ltd 育毛料
US5118711A (en) * 1990-09-27 1992-06-02 International Flavors & Fragrances Inc. Ketone, ketoesters and alcohol in repelling insects; use of aliphatic ester in attracting insects and process and apparatus for determination of insect repellency and attractancy
US5436226A (en) * 1993-11-03 1995-07-25 The United States Of America, As Represented By The Secretary Of Agriculture Natural suppression of sprouting in stored potatoes using jasmonates
ES2176686T3 (es) * 1996-02-28 2002-12-01 Nippon Zeon Co Regulador del crecimiento para plantas de cultivo y procedimiento para la regulacion del crecimiento de plantas de cultivo.
JP3568325B2 (ja) 1996-07-12 2004-09-22 株式会社ノエビア 抗アンドロゲン剤及び養毛剤並びに毛髪用化粧料
US6469061B1 (en) * 2001-04-04 2002-10-22 Ramot University Authority For Applied Research And Industrial Development Limited Jasmonate pharmaceutical composition for treatment of cancer
WO2005054172A2 (en) * 2003-12-02 2005-06-16 Ramot At Tel-Aviv University Ltd. Jasmonate derivative compounds, pharmaceuticals compositions and methods of use thereof

Also Published As

Publication number Publication date
WO2005054172A3 (en) 2005-07-07
EP1689696A2 (en) 2006-08-16
CA2548173A1 (en) 2005-06-16
WO2005054172A2 (en) 2005-06-16
US20070142474A1 (en) 2007-06-21
CN1902156A (zh) 2007-01-24
US20080319066A1 (en) 2008-12-25
US7425651B2 (en) 2008-09-16
US7683211B2 (en) 2010-03-23
JP2007514663A (ja) 2007-06-07

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Legal Events

Date Code Title Description
MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application