AU2003258457A1 - Method for the biotechnological production of citric acid by means of a genetically-modified yeast yarrowia lipolytica - Google Patents

Method for the biotechnological production of citric acid by means of a genetically-modified yeast yarrowia lipolytica

Info

Publication number
AU2003258457A1
AU2003258457A1 AU2003258457A AU2003258457A AU2003258457A1 AU 2003258457 A1 AU2003258457 A1 AU 2003258457A1 AU 2003258457 A AU2003258457 A AU 2003258457A AU 2003258457 A AU2003258457 A AU 2003258457A AU 2003258457 A1 AU2003258457 A1 AU 2003258457A1
Authority
AU
Australia
Prior art keywords
genetically
citric acid
yarrowia lipolytica
modified yeast
biotechnological production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003258457A
Other languages
English (en)
Inventor
Gerold Barth
Andre Forster
Thomas Juretzek
Kordula Kruse
Stephan Mauersberger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Technische Universitaet Dresden
Original Assignee
Technische Universitaet Dresden
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Technische Universitaet Dresden filed Critical Technische Universitaet Dresden
Publication of AU2003258457A1 publication Critical patent/AU2003258457A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C12P7/48—Tricarboxylic acids, e.g. citric acid

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU2003258457A 2002-07-16 2003-07-16 Method for the biotechnological production of citric acid by means of a genetically-modified yeast yarrowia lipolytica Abandoned AU2003258457A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10233600.8 2002-07-16
DE10233600 2002-07-16
PCT/DE2003/002458 WO2004009828A1 (de) 2002-07-16 2003-07-16 Verfahren zur biotechnologischen herstellung von citronensäure mit einer genetisch veränderten hefe yarrowia lipolytica

Publications (1)

Publication Number Publication Date
AU2003258457A1 true AU2003258457A1 (en) 2004-02-09

Family

ID=30010341

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003258457A Abandoned AU2003258457A1 (en) 2002-07-16 2003-07-16 Method for the biotechnological production of citric acid by means of a genetically-modified yeast yarrowia lipolytica

Country Status (5)

Country Link
CN (1) CN1723286A (zh)
AU (1) AU2003258457A1 (zh)
DE (1) DE10333144B4 (zh)
RU (1) RU2005102929A (zh)
WO (1) WO2004009828A1 (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0619091A2 (pt) * 2005-12-01 2011-09-13 Dsm Ip Assests Bv novos genes úteis para a produção industrial de ácido cìtrico
DE102011056290A1 (de) 2011-12-12 2013-06-13 Thyssenkrupp Uhde Gmbh Pilzstämme mit genetischer modifikation betreffend einen carbonsäure-transporter
EP3536784A1 (en) * 2018-03-05 2019-09-11 ACIB GmbH Host cell engineered for improved metabolite production

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD227448A1 (de) * 1984-10-18 1985-09-18 Akad Wissenschaften Ddr Verfahren zur herstellung von zitronensaeure auf mikrobiellem wege
DD259637A1 (de) * 1987-04-09 1988-08-31 Adw Ddr Verfahren zur herstellung von isozitratlyase in rekombinanten mikroorganismen
DE19525282A1 (de) * 1995-06-29 1997-01-02 Max Delbrueck Centrum Expressionskassetten zur heterologen Expression von Proteinen in der Hefe Yarrowia lipolytica unter Kontrolle des regulierbaren Promotors der Isocitratlyase
DE19932811A1 (de) * 1998-07-10 2000-01-20 Univ Dresden Tech Rekombinante haploide oder diploide Yarrowia lipolytica Zellen zur funktionellen heterologen Expression von Cytochrom P450 Systemen

Also Published As

Publication number Publication date
RU2005102929A (ru) 2005-08-10
CN1723286A (zh) 2006-01-18
DE10333144A1 (de) 2004-02-05
DE10333144B4 (de) 2006-06-29
WO2004009828A1 (de) 2004-01-29

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase