AU2003241585B2 - Use of mGluR5 antagonists for the treatment of GERD - Google Patents
Use of mGluR5 antagonists for the treatment of GERD Download PDFInfo
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- AU2003241585B2 AU2003241585B2 AU2003241585A AU2003241585A AU2003241585B2 AU 2003241585 B2 AU2003241585 B2 AU 2003241585B2 AU 2003241585 A AU2003241585 A AU 2003241585A AU 2003241585 A AU2003241585 A AU 2003241585A AU 2003241585 B2 AU2003241585 B2 AU 2003241585B2
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- antagonist
- glutamate receptor
- metabotropic glutamate
- treatment
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- Steroid Compounds (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
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| PCT/US2003/016223 WO2004000316A1 (en) | 2002-06-20 | 2003-06-19 | Use of mglur5 antagonists for the treatment of gerd |
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| US7964609B2 (en) | 2002-06-20 | 2011-06-21 | Astrazeneca Ab | Use of mGluR5 antagonists for the treatment of gerd |
| SE0303418D0 (sv) * | 2003-12-17 | 2003-12-17 | Astrazeneca Ab | New use 1 |
| WO2005060971A1 (en) * | 2003-12-18 | 2005-07-07 | Astrazeneca Ab | Treatment of reflux-related diseases |
| WO2005060961A2 (en) * | 2003-12-18 | 2005-07-07 | Astrazeneca Ab | Treatment of transient lower esophageal sphincter relaxations (tlesrs) and gastro-esophageal reflux disease (gerd) |
| WO2005077368A2 (en) * | 2004-02-03 | 2005-08-25 | Astrazeneca Ab | Treatment of gastro-esophageal reflux disease (gerd) |
| WO2005077345A1 (en) * | 2004-02-03 | 2005-08-25 | Astrazeneca Ab | Compounds for the treatment of gastro-esophageal reflux disease |
| CN1918154A (zh) * | 2004-02-18 | 2007-02-21 | 阿斯利康(瑞典)有限公司 | 多杂环化合物及其作为代谢型谷氨酸受体拮抗剂的用途 |
| RU2006128445A (ru) * | 2004-02-18 | 2008-03-27 | Астразенека Аб (Se) | Ацетилиновые пиперазиновые соединения и их применение в качестве антагонистов метаботропных глутаматных рецепторов |
| GB0514296D0 (en) * | 2005-07-12 | 2005-08-17 | Novartis Ag | Organic compounds |
| SI2001849T1 (sl) * | 2006-03-29 | 2015-02-27 | F. Hoffmann-La Roche Ag | Derivati piridina in pirimidina kot antagonisti mglur2 |
| KR20090061041A (ko) | 2006-09-11 | 2009-06-15 | 노파르티스 아게 | 대사성 글루타메이트 수용체의 조절제로서의 니코틴산 유도체 |
| JP2008245225A (ja) * | 2007-03-29 | 2008-10-09 | Kddi Corp | 波長パス経路決定装置、波長パス設定制御システム及びプログラム |
| WO2009024491A1 (en) * | 2007-08-20 | 2009-02-26 | F. Hoffmann-La Roche Ag | Use of mglur5 antagonists for the treatment of gerd |
| EP2826478A1 (en) | 2008-06-30 | 2015-01-21 | Novartis AG | Combinations comprising mglur modulators for the treatment of parkinson's disease |
| WO2011009890A2 (en) | 2009-07-23 | 2011-01-27 | Novartis Ag | Use of azabicycloalkyl derivatives or pyrrolidine-2-one derivatives |
| JO3250B1 (ar) | 2009-09-22 | 2018-09-16 | Novartis Ag | إستعمال منشطات مستقبل نيكوتينيك أسيتيل كولين ألفا 7 |
| EP2490691A1 (en) | 2009-10-20 | 2012-08-29 | Novartis AG | Use of 1h-quinazoline-2,4-diones |
| RU2013103001A (ru) | 2010-06-24 | 2014-07-27 | Новартис Аг | Применение 1н-хиназолин-2,4-дионов |
| US20140171448A1 (en) | 2011-01-27 | 2014-06-19 | Novartis Ag | Use of nicotinic acetylcholine receptor alpha 7 activators |
| WO2013036224A1 (en) | 2011-09-07 | 2013-03-14 | Novartis Ag | Use of 1h-quinazoline- 2, 4 -diones for use in the prevention or treatment photosensitive epilepsy |
| BR112015016994A8 (pt) | 2013-01-15 | 2018-01-23 | Novartis Ag | uso de agonistas do receptor alfa 7 nicotínico de acetilcolina |
| WO2014111837A1 (en) | 2013-01-15 | 2014-07-24 | Novartis Ag | Use of alpha 7 nicotinic acetylcholine receptor agonists |
| US20220387410A1 (en) * | 2019-11-05 | 2022-12-08 | Claes Thulin | 4-[5-[(rac)-1-[5-(3-Chlorophenyl)-3-isoxazolyl]ethoxy]-4-methyl-4H-1,2,4-triazol-3-yl]pyridine for use in prevention and/or treatment of surmenage in a mammal |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2001012627A1 (en) * | 1999-08-19 | 2001-02-22 | Nps Pharmaceuticals, Inc. | Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists |
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| AU594424B2 (en) * | 1986-01-03 | 1990-03-08 | University Of Melbourne, The | Gastro-oesophageal reflux composition |
| SE9603408D0 (sv) * | 1996-09-18 | 1996-09-18 | Astra Ab | Medical use |
| JP2002515448A (ja) * | 1998-05-15 | 2002-05-28 | アフトン・コーポレーシヨン | 食道逆流病の処置法 |
| RU2144331C1 (ru) * | 1998-11-05 | 2000-01-20 | Московский НИИ уха, горла и носа | Способ лечения хронического гиперпластического ларингита |
| US7115630B2 (en) * | 2000-10-02 | 2006-10-03 | Janssen Pharmaceutica N.V. | Metabotropic glutamate receptor antagonists |
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2002
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2003
- 2003-06-19 DK DK03731333T patent/DK1513525T3/da active
- 2003-06-19 ES ES03731333T patent/ES2304510T3/es not_active Expired - Lifetime
- 2003-06-19 PL PL03372186A patent/PL372186A1/xx not_active Application Discontinuation
- 2003-06-19 PT PT03731333T patent/PT1513525E/pt unknown
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- 2003-06-19 SI SI200331220T patent/SI1513525T1/sl unknown
- 2003-06-19 DE DE60320990T patent/DE60320990D1/de not_active Expired - Lifetime
- 2003-06-19 JP JP2004515703A patent/JP4683920B2/ja not_active Expired - Fee Related
- 2003-06-19 WO PCT/US2003/016223 patent/WO2004000316A1/en not_active Ceased
- 2003-06-19 UA UA20041210177A patent/UA81627C2/ru unknown
- 2003-06-19 AU AU2003241585A patent/AU2003241585B2/en not_active Ceased
- 2003-06-19 NZ NZ536559A patent/NZ536559A/en not_active IP Right Cessation
- 2003-06-19 CN CNB038141760A patent/CN100430056C/zh not_active Expired - Fee Related
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- 2003-06-19 AT AT03731333T patent/ATE395059T1/de active
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001012627A1 (en) * | 1999-08-19 | 2001-02-22 | Nps Pharmaceuticals, Inc. | Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists |
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| Gasparini et al. Neuropharmacology (1999) vol. 38, no. 10 pages 1493-1503 * |
| Knopfel et al. Journal of Medicinal Chemistry (1995) vol. 38, no. 9 pages 1417-1426 * |
Also Published As
| Publication number | Publication date |
|---|---|
| SI1513525T1 (sl) | 2008-08-31 |
| ZA200409908B (en) | 2006-08-30 |
| NO20050154L (no) | 2005-01-11 |
| SE0201943D0 (sv) | 2002-06-20 |
| MXPA04012659A (es) | 2006-05-25 |
| AU2003241585A1 (en) | 2004-01-06 |
| PL372186A1 (en) | 2005-07-11 |
| BR0311759A (pt) | 2005-03-08 |
| ES2304510T3 (es) | 2008-10-16 |
| PT1513525E (pt) | 2008-06-24 |
| DK1513525T3 (da) | 2008-08-11 |
| CN1662235A (zh) | 2005-08-31 |
| HK1075833A1 (en) | 2005-12-30 |
| RU2005101411A (ru) | 2005-07-10 |
| EP1513525A1 (en) | 2005-03-16 |
| JP2006507225A (ja) | 2006-03-02 |
| IS7654A (is) | 2005-01-19 |
| UA81627C2 (ru) | 2008-01-25 |
| CN100430056C (zh) | 2008-11-05 |
| CA2489730C (en) | 2011-11-22 |
| CY1107954T1 (el) | 2013-09-04 |
| IL165138A0 (en) | 2005-12-18 |
| RU2324484C2 (ru) | 2008-05-20 |
| WO2004000316A1 (en) | 2003-12-31 |
| JP4683920B2 (ja) | 2011-05-18 |
| DE60320990D1 (de) | 2008-06-26 |
| ATE395059T1 (de) | 2008-05-15 |
| JP2011068669A (ja) | 2011-04-07 |
| CA2489730A1 (en) | 2003-12-31 |
| NZ536559A (en) | 2007-08-31 |
| EP1513525B1 (en) | 2008-05-14 |
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