AU2003206267B2 - Short interfering RNA molecules directed towards a tissue factor coding nucleic acid - Google Patents

Short interfering RNA molecules directed towards a tissue factor coding nucleic acid Download PDF

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Publication number
AU2003206267B2
AU2003206267B2 AU2003206267A AU2003206267A AU2003206267B2 AU 2003206267 B2 AU2003206267 B2 AU 2003206267B2 AU 2003206267 A AU2003206267 A AU 2003206267A AU 2003206267 A AU2003206267 A AU 2003206267A AU 2003206267 B2 AU2003206267 B2 AU 2003206267B2
Authority
AU
Australia
Prior art keywords
seq
sirna
molecule
rna molecule
rna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2003206267A
Other languages
English (en)
Other versions
AU2003206267A1 (en
Inventor
Mohammed Amarzguioui
Eshrat Babaie
Torgeir Holen
Hans Prydz
Merete Wiiger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SIRNASENSE AS
Original Assignee
SIRNASENSE AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from NO20020612A external-priority patent/NO20020612D0/no
Priority claimed from NO20024987A external-priority patent/NO20024987D0/no
Application filed by SIRNASENSE AS filed Critical SIRNASENSE AS
Publication of AU2003206267A1 publication Critical patent/AU2003206267A1/en
Assigned to SIRNASENSE AS reassignment SIRNASENSE AS Request for Assignment Assignors: AMARZGUIOUI, MOHAMMED, BABAIE, ESHRAT, HOLEN, TORGEIR, PRYDZ, HANS, WIIGER, MERETE
Application granted granted Critical
Publication of AU2003206267B2 publication Critical patent/AU2003206267B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU2003206267A 2002-02-07 2003-02-06 Short interfering RNA molecules directed towards a tissue factor coding nucleic acid Ceased AU2003206267B2 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
NO20020612A NO20020612D0 (no) 2002-02-07 2002-02-07 Posttranskripsjonell inhibering ved korte interfererende RNA
NO20020612 2002-02-07
US35451502P 2002-02-08 2002-02-08
US60/354,515 2002-02-08
NO20024987A NO20024987D0 (no) 2002-02-07 2002-10-16 Posttranskripsjonell inhibering ved korte interfererende RNA'er
NO20024987 2002-10-16
PCT/NO2003/000045 WO2003066650A2 (en) 2002-02-07 2003-02-06 Short interfering rna molecules directed towards a tissue factor coding nucleic acid

Publications (2)

Publication Number Publication Date
AU2003206267A1 AU2003206267A1 (en) 2003-09-02
AU2003206267B2 true AU2003206267B2 (en) 2008-10-02

Family

ID=27738950

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003206267A Ceased AU2003206267B2 (en) 2002-02-07 2003-02-06 Short interfering RNA molecules directed towards a tissue factor coding nucleic acid

Country Status (9)

Country Link
EP (1) EP1554381B1 (OSRAM)
JP (1) JP4335012B2 (OSRAM)
AT (1) ATE449846T1 (OSRAM)
AU (1) AU2003206267B2 (OSRAM)
CA (1) CA2475447A1 (OSRAM)
DE (1) DE60330263D1 (OSRAM)
DK (1) DK1554381T3 (OSRAM)
ES (1) ES2336440T3 (OSRAM)
WO (1) WO2003066650A2 (OSRAM)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2534996A1 (en) * 2003-08-06 2005-05-06 Hans Prydz The use of sirna silencing in the prevention of metastasis
US7919583B2 (en) 2005-08-08 2011-04-05 Discovery Genomics, Inc. Integration-site directed vector systems
WO2010008562A2 (en) 2008-07-16 2010-01-21 Recombinetics Methods and materials for producing transgenic animals
WO2011084193A1 (en) * 2010-01-07 2011-07-14 Quark Pharmaceuticals, Inc. Oligonucleotide compounds comprising non-nucleotide overhangs

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6387366B1 (en) * 1998-12-31 2002-05-14 Alg Company Methods for reducing adverse side effects associated with cellular transplantation
US7045350B2 (en) * 2001-08-30 2006-05-16 Mount Sinai School Of Medicine Of New York University Alternatively spliced circulating tissue factor

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Holden et al (2002), Nucleic Acid Research , Vol 30 (8): 1757-1766 *

Also Published As

Publication number Publication date
ES2336440T3 (es) 2010-04-13
JP2005532038A (ja) 2005-10-27
DE60330263D1 (de) 2010-01-07
EP1554381B1 (en) 2009-11-25
JP4335012B2 (ja) 2009-09-30
ATE449846T1 (de) 2009-12-15
AU2003206267A1 (en) 2003-09-02
EP1554381A2 (en) 2005-07-20
WO2003066650A3 (en) 2004-05-21
CA2475447A1 (en) 2003-08-14
DK1554381T3 (da) 2010-03-29
WO2003066650A2 (en) 2003-08-14

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Legal Events

Date Code Title Description
PC1 Assignment before grant (sect. 113)

Owner name: SIRNASENSE AS

Free format text: FORMER APPLICANT(S): PRYDZ, HANS; HOLEN, TORGEIR ; BABAIE, ESHRAT; AMARZGUIOUI, MOHAMMED; WIIGER, MERETE

FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired