DE60330263D1 - Post-transcriptional silencing der gewebefaktor expression durch kurze interferierende rnas - Google Patents
Post-transcriptional silencing der gewebefaktor expression durch kurze interferierende rnasInfo
- Publication number
- DE60330263D1 DE60330263D1 DE60330263T DE60330263T DE60330263D1 DE 60330263 D1 DE60330263 D1 DE 60330263D1 DE 60330263 T DE60330263 T DE 60330263T DE 60330263 T DE60330263 T DE 60330263T DE 60330263 D1 DE60330263 D1 DE 60330263D1
- Authority
- DE
- Germany
- Prior art keywords
- tissue factor
- short interfering
- post
- interfering rnas
- factor expression
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 102000002262 Thromboplastin Human genes 0.000 title abstract 3
- 108010000499 Thromboplastin Proteins 0.000 title abstract 3
- 108091032973 (ribonucleotides)n+m Proteins 0.000 title abstract 2
- 102000040650 (ribonucleotides)n+m Human genes 0.000 title abstract 2
- 230000030279 gene silencing Effects 0.000 title 1
- 230000002452 interceptive effect Effects 0.000 title 1
- 230000001124 posttranscriptional effect Effects 0.000 title 1
- 108020004459 Small interfering RNA Proteins 0.000 abstract 3
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO20020612A NO20020612D0 (no) | 2002-02-07 | 2002-02-07 | Posttranskripsjonell inhibering ved korte interfererende RNA |
| US35451502P | 2002-02-08 | 2002-02-08 | |
| NO20024987A NO20024987D0 (no) | 2002-02-07 | 2002-10-16 | Posttranskripsjonell inhibering ved korte interfererende RNA'er |
| PCT/NO2003/000045 WO2003066650A2 (en) | 2002-02-07 | 2003-02-06 | Short interfering rna molecules directed towards a tissue factor coding nucleic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60330263D1 true DE60330263D1 (de) | 2010-01-07 |
Family
ID=27738950
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60330263T Expired - Lifetime DE60330263D1 (de) | 2002-02-07 | 2003-02-06 | Post-transcriptional silencing der gewebefaktor expression durch kurze interferierende rnas |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1554381B1 (OSRAM) |
| JP (1) | JP4335012B2 (OSRAM) |
| AT (1) | ATE449846T1 (OSRAM) |
| AU (1) | AU2003206267B2 (OSRAM) |
| CA (1) | CA2475447A1 (OSRAM) |
| DE (1) | DE60330263D1 (OSRAM) |
| DK (1) | DK1554381T3 (OSRAM) |
| ES (1) | ES2336440T3 (OSRAM) |
| WO (1) | WO2003066650A2 (OSRAM) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2534996A1 (en) * | 2003-08-06 | 2005-05-06 | Hans Prydz | The use of sirna silencing in the prevention of metastasis |
| US7919583B2 (en) | 2005-08-08 | 2011-04-05 | Discovery Genomics, Inc. | Integration-site directed vector systems |
| WO2010008562A2 (en) | 2008-07-16 | 2010-01-21 | Recombinetics | Methods and materials for producing transgenic animals |
| WO2011084193A1 (en) * | 2010-01-07 | 2011-07-14 | Quark Pharmaceuticals, Inc. | Oligonucleotide compounds comprising non-nucleotide overhangs |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6387366B1 (en) * | 1998-12-31 | 2002-05-14 | Alg Company | Methods for reducing adverse side effects associated with cellular transplantation |
| WO2003020111A2 (en) * | 2001-08-30 | 2003-03-13 | Mount Sinai School Of Medicine Of New York University | Alternatively spliced circulating tissue factor |
-
2003
- 2003-02-06 ES ES03703543T patent/ES2336440T3/es not_active Expired - Lifetime
- 2003-02-06 EP EP03703543A patent/EP1554381B1/en not_active Expired - Lifetime
- 2003-02-06 WO PCT/NO2003/000045 patent/WO2003066650A2/en not_active Ceased
- 2003-02-06 CA CA002475447A patent/CA2475447A1/en not_active Abandoned
- 2003-02-06 DK DK03703543.3T patent/DK1554381T3/da active
- 2003-02-06 DE DE60330263T patent/DE60330263D1/de not_active Expired - Lifetime
- 2003-02-06 JP JP2003566021A patent/JP4335012B2/ja not_active Expired - Fee Related
- 2003-02-06 AT AT03703543T patent/ATE449846T1/de not_active IP Right Cessation
- 2003-02-06 AU AU2003206267A patent/AU2003206267B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP1554381B1 (en) | 2009-11-25 |
| ES2336440T3 (es) | 2010-04-13 |
| CA2475447A1 (en) | 2003-08-14 |
| WO2003066650A3 (en) | 2004-05-21 |
| WO2003066650A2 (en) | 2003-08-14 |
| EP1554381A2 (en) | 2005-07-20 |
| ATE449846T1 (de) | 2009-12-15 |
| JP2005532038A (ja) | 2005-10-27 |
| AU2003206267B2 (en) | 2008-10-02 |
| JP4335012B2 (ja) | 2009-09-30 |
| AU2003206267A1 (en) | 2003-09-02 |
| DK1554381T3 (da) | 2010-03-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE602005015994D1 (de) | siRNA-VERMITTELTES GEN-SILENCING VON ALPHA-SYNUKLEIN | |
| EA200870366A1 (ru) | Короткая внутренне сегментированная интерферирующая рнк | |
| MY163004A (en) | Modulation of signal transducer and activator of transcription 3 (stat3) expression | |
| WO2007053696A3 (en) | Rnai inhibition of influenza virus replication | |
| TN2009000521A1 (en) | Rnai inhibition of alpha-enac expression | |
| TW200716646A (en) | (S)-N-methylnaltrexone | |
| EP1824872A4 (en) | RNAI MODULATION OF MLL-AF4 AND USES THEREOF | |
| WO2011008730A3 (en) | Chemical modification of small hairpin rnas for inhibition of gene expression | |
| CY1112383T1 (el) | Αναστολεις της πρωτεϊνης ενεργοποιησης της 5-λιποξυγενασης (flap) | |
| ATE513843T1 (de) | Abstellen von genen in vivo durch chemischmodifizierte und stabile sirna | |
| WO2007092182A3 (en) | Rna interference agents for therapeutic use | |
| TW200510325A (en) | 2-acylamino-4-phenylthiazole derivatives, preparation thereof and therapeutic application thereof | |
| TW200602324A (en) | Tetrahydro-indazole cannabinoid modulators cross reference to related applications | |
| EA200870514A1 (ru) | Ацетиленовые гетероарильные соединения | |
| WO2008094516A8 (en) | Multi-targeting short interfering rnas | |
| IL192103A0 (en) | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of depression | |
| DK2274373T3 (da) | Oxygenfjernende blandinger | |
| EA201070009A1 (ru) | Производные 7-алкинил-1,8-нафтиридонов, их получение и их применение в терапии | |
| EA017490B9 (ru) | 11-бета-гидроксиандроста-4-ен-3-оны | |
| MX2010008326A (es) | Metodo y composiciones capaces de provocar un silenciamiento post-transcripcional de la expresion genica de forma sinergica. | |
| DK1931335T3 (da) | Hexahydro-cyclooctyl-pyrazol-cannabinoid-modulatorer | |
| TW200740429A (en) | Methods and dosage forms for reducing side effects of carbamate compounds | |
| WO2005073250A3 (en) | Medical treatment using an rna1 targeting a human notch signalling pathway member | |
| DE60330263D1 (de) | Post-transcriptional silencing der gewebefaktor expression durch kurze interferierende rnas | |
| WO2007092607A3 (en) | Treatment of hemorrhagic viral infections using a tissue factor inhibitor |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |