AU2002326070A1 - Peyers's patch and/or m-celle targeting ligands - Google Patents
Peyers's patch and/or m-celle targeting ligandsInfo
- Publication number
- AU2002326070A1 AU2002326070A1 AU2002326070A AU2002326070A AU2002326070A1 AU 2002326070 A1 AU2002326070 A1 AU 2002326070A1 AU 2002326070 A AU2002326070 A AU 2002326070A AU 2002326070 A AU2002326070 A AU 2002326070A AU 2002326070 A1 AU2002326070 A1 AU 2002326070A1
- Authority
- AU
- Australia
- Prior art keywords
- patch
- peyers
- celle
- targeting ligands
- ligands
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000003446 ligand Substances 0.000 title abstract 3
- 230000008685 targeting Effects 0.000 title abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 210000000981 epithelium Anatomy 0.000 abstract 1
- 230000000968 intestinal effect Effects 0.000 abstract 1
- 210000003126 m-cell Anatomy 0.000 abstract 1
- 210000001986 peyer's patch Anatomy 0.000 abstract 1
- 239000008177 pharmaceutical agent Substances 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 210000001519 tissue Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4725—Proteoglycans, e.g. aggreccan
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30259101P | 2001-07-02 | 2001-07-02 | |
| US60/302,591 | 2001-07-02 | ||
| PCT/IB2002/003401 WO2003004517A2 (en) | 2001-07-02 | 2002-06-28 | Peyers's patch and/or m-celle targeting ligands |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2002326070A1 true AU2002326070A1 (en) | 2003-01-21 |
Family
ID=23168408
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2002326070A Abandoned AU2002326070A1 (en) | 2001-07-02 | 2002-06-28 | Peyers's patch and/or m-celle targeting ligands |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US6916789B2 (https=) |
| EP (1) | EP1432729B1 (https=) |
| JP (1) | JP4383855B2 (https=) |
| AT (1) | ATE414100T1 (https=) |
| AU (1) | AU2002326070A1 (https=) |
| CA (1) | CA2451741C (https=) |
| DE (1) | DE60229867D1 (https=) |
| WO (1) | WO2003004517A2 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6521737B1 (en) * | 1995-11-10 | 2003-02-18 | Elan Corporation, Plc | Peptides which enhance transport across tissues and methods of identifying and using the same |
| ATE414100T1 (de) * | 2001-07-02 | 2008-11-15 | Merrion Res Iii Ltd | Zielgerichtete ligande gegen peyer's flecke- und/oder m-zellen |
| WO2004108755A2 (en) * | 2003-06-10 | 2004-12-16 | University Of Saskatchewan | Chimeric adenovirus capsid proteins |
| AU2012201102B2 (en) * | 2004-06-23 | 2014-05-08 | Ferguson, Ian Andrew | Agents and methods for early diagnosis and monitoring of Alzheimer's disease and other neurological disorders |
| DE102005031755B9 (de) * | 2005-07-01 | 2010-04-08 | Technische Universität Dresden | Salmonella spp. bindende Peptide, dafür kodierende Nukleinsäuren, deren Verwendungen und Verfahren und Kits zur Anreicherung, Immobilisierung und zum Nachweis von Salmonella spp. |
| WO2007137174A2 (en) * | 2006-05-18 | 2007-11-29 | The Ohio State University Research Foundation | Compositions and methods for the detection of vulnerable plaque |
| CN104884065B (zh) | 2012-09-21 | 2019-01-01 | 强烈治疗剂公司 | 治疗癌症的方法 |
| JP6618892B2 (ja) | 2013-04-23 | 2019-12-11 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 細菌バイオフィルムの遺伝的リプログラミング |
| EP3280397A4 (en) | 2015-04-06 | 2018-08-22 | President and Fellows of Harvard College | Biosynthetic amyloid-based materials displaying functional protein sequences |
| US11098133B2 (en) | 2016-05-19 | 2021-08-24 | President And Fellows Of Harvard College | Methods of making gels and films using curli nanofibers |
| TW201829470A (zh) | 2016-10-26 | 2018-08-16 | 廖朝暐 | 用於免疫增強的融合胜肽及使用其增強誘發免疫反應的方法 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1986004608A1 (en) * | 1985-02-05 | 1986-08-14 | Synergen Biologicals, Inc. | Metalloproteinase inhibitor sequence recombinant vector system for using same and recombinant-dna method for the manufacture of same |
| IL84167A (en) * | 1986-10-24 | 1991-04-15 | Southern Res Inst | Oral delivery of bioactive agents to and through the peyer's patch by use of microencapsulation |
| US5254342A (en) | 1991-09-30 | 1993-10-19 | University Of Southern California | Compositions and methods for enhanced transepithelial and transendothelial transport or active agents |
| GB9201139D0 (en) * | 1992-01-20 | 1992-03-11 | Connaught Lab | Synthetic peptides for a rubella vaccine |
| WO1993020834A1 (en) | 1992-04-10 | 1993-10-28 | Brigham And Women's Hospital | Methods and compositions for oral delivery of therapeutic agents |
| US5534496A (en) | 1992-07-07 | 1996-07-09 | University Of Southern California | Methods and compositions to enhance epithelial drug transport |
| EP0750630A4 (en) * | 1994-03-11 | 1998-01-07 | Ariad Pharma Inc | METHOD AND MATERIALS FOR IDENTIFYING INHIBITORS OF MOLECULAR INTERACTIONS, WHICH ARE BROUGHT BY THE SH3 DOMAINS |
| US5831008A (en) * | 1994-08-18 | 1998-11-03 | La Jolla Cancer Research Foundation | Retinoblastoma protein-interacting zinc finger proteins |
| US6086875A (en) | 1995-01-17 | 2000-07-11 | The Brigham And Women's Hospital, Inc. | Receptor specific transepithelial transport of immunogens |
| US6030613A (en) | 1995-01-17 | 2000-02-29 | The Brigham And Women's Hospital, Inc. | Receptor specific transepithelial transport of therapeutics |
| IE80466B1 (en) | 1995-11-10 | 1998-07-29 | Elan Corp Plc | Peptides which enhance transport across tissues and methods of identifying and using the same |
| NZ322175A (en) * | 1995-11-10 | 1999-02-25 | Elan Corp Plc | Peptides which enhance transport across tissues and methods of identifying the same |
| US6261787B1 (en) | 1996-06-03 | 2001-07-17 | Case Western Reserve University | Bifunctional molecules for delivery of therapeutics |
| US6060082A (en) | 1997-04-18 | 2000-05-09 | Massachusetts Institute Of Technology | Polymerized liposomes targeted to M cells and useful for oral or mucosal drug delivery |
| WO1998051325A2 (en) * | 1997-05-15 | 1998-11-19 | Cytogen Corporation | Random peptides that bind to gastro-intestinal tract (git) transport receptors and related methods |
| JP4799790B2 (ja) * | 1999-09-27 | 2011-10-26 | メリオン リサーチ スリー リミテッド | 膜転位ペプチド、同ペプチドを含有する組成物、同ペプチドを含有する医薬製剤及び同ペプチドの製剤の調製における使用 |
| JP2001245675A (ja) * | 1999-12-28 | 2001-09-11 | Kyogo Ito | 腫瘍抗原 |
| CN1323825A (zh) * | 2000-05-16 | 2001-11-28 | 上海博德基因开发有限公司 | 一种新的多肽——人网格蛋白轻链9和编码这种多肽的多核苷酸 |
| AU2002254161A1 (en) * | 2001-03-12 | 2002-09-24 | Montana State University-Bozeman | M cell directed vaccines |
| EP1419252A2 (en) * | 2001-04-04 | 2004-05-19 | Merrion Research I Limited | Genetic analysis of peyers's patches and m cells and methods and compositions targeting peyer's patches and m cell receptors |
| ATE414100T1 (de) * | 2001-07-02 | 2008-11-15 | Merrion Res Iii Ltd | Zielgerichtete ligande gegen peyer's flecke- und/oder m-zellen |
-
2002
- 2002-06-28 AT AT02760458T patent/ATE414100T1/de not_active IP Right Cessation
- 2002-06-28 US US10/185,815 patent/US6916789B2/en not_active Expired - Fee Related
- 2002-06-28 JP JP2003510683A patent/JP4383855B2/ja not_active Expired - Fee Related
- 2002-06-28 AU AU2002326070A patent/AU2002326070A1/en not_active Abandoned
- 2002-06-28 EP EP02760458A patent/EP1432729B1/en not_active Expired - Lifetime
- 2002-06-28 DE DE60229867T patent/DE60229867D1/de not_active Expired - Lifetime
- 2002-06-28 WO PCT/IB2002/003401 patent/WO2003004517A2/en not_active Ceased
- 2002-06-28 CA CA2451741A patent/CA2451741C/en not_active Expired - Fee Related
-
2005
- 2005-06-07 US US11/147,083 patent/US7485321B2/en not_active Expired - Fee Related
-
2008
- 2008-12-19 US US12/340,019 patent/US20100016549A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ATE414100T1 (de) | 2008-11-15 |
| JP2005503782A (ja) | 2005-02-10 |
| US7485321B2 (en) | 2009-02-03 |
| EP1432729A2 (en) | 2004-06-30 |
| WO2003004517A2 (en) | 2003-01-16 |
| JP4383855B2 (ja) | 2009-12-16 |
| US6916789B2 (en) | 2005-07-12 |
| EP1432729B1 (en) | 2008-11-12 |
| CA2451741A1 (en) | 2003-01-16 |
| US20050227924A1 (en) | 2005-10-13 |
| US20100016549A1 (en) | 2010-01-21 |
| CA2451741C (en) | 2014-02-18 |
| US20030096354A1 (en) | 2003-05-22 |
| DE60229867D1 (de) | 2008-12-24 |
| WO2003004517A3 (en) | 2004-04-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |