AU2002251257B2 - Methods of Using O6-alkylguanine-DNA Alkyltransferases - Google Patents

Methods of Using O6-alkylguanine-DNA Alkyltransferases Download PDF

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Publication number
AU2002251257B2
AU2002251257B2 AU2002251257A AU2002251257A AU2002251257B2 AU 2002251257 B2 AU2002251257 B2 AU 2002251257B2 AU 2002251257 A AU2002251257 A AU 2002251257A AU 2002251257 A AU2002251257 A AU 2002251257A AU 2002251257 B2 AU2002251257 B2 AU 2002251257B2
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AU
Australia
Prior art keywords
agt
fusion protein
label
protein
alkylguanine
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Ceased
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AU2002251257A
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AU2002251257A1 (en
Inventor
Susanne Gendreizig
Kai Johnsson
Antje Keppler
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Ecole Polytechnique Federale de Lausanne EPFL
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Ecole Polytechnique Federale de Lausanne EPFL
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Publication of AU2002251257B2 publication Critical patent/AU2002251257B2/en
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Ceased legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/20Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/60Fusion polypeptide containing spectroscopic/fluorescent detection, e.g. green fluorescent protein [GFP]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2002251257A 2001-04-10 2002-04-05 Methods of Using O6-alkylguanine-DNA Alkyltransferases Ceased AU2002251257B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28276601P 2001-04-10 2001-04-10
US60/282,766 2001-04-10
PCT/GB2002/001636 WO2002083937A2 (en) 2001-04-10 2002-04-05 Methods using o6-alkylguanine-dna alkyltransferases

Publications (2)

Publication Number Publication Date
AU2002251257A1 AU2002251257A1 (en) 2003-04-17
AU2002251257B2 true AU2002251257B2 (en) 2007-08-30

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Family Applications (1)

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AU2002251257A Ceased AU2002251257B2 (en) 2001-04-10 2002-04-05 Methods of Using O6-alkylguanine-DNA Alkyltransferases

Country Status (14)

Country Link
US (2) US7939284B2 (https=)
EP (4) EP1410023B1 (https=)
JP (2) JP4195815B2 (https=)
KR (1) KR20040039194A (https=)
CN (2) CN1295510C (https=)
AT (3) ATE419378T1 (https=)
AU (1) AU2002251257B2 (https=)
CA (1) CA2443570A1 (https=)
DE (3) DE60212642T2 (https=)
DK (1) DK1410023T3 (https=)
IL (1) IL157880A0 (https=)
NZ (3) NZ528594A (https=)
WO (1) WO2002083937A2 (https=)
ZA (1) ZA200307442B (https=)

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US8163479B2 (en) 2004-03-02 2012-04-24 Ecole Polytechnique Federale De Lausanne Specific substrates for O6-alkylguanine-DNA alkyltransferase
US7888090B2 (en) 2004-03-02 2011-02-15 Ecole Polytechnique Federale De Lausanne Mutants of O6-alkylguanine-DNA alkyltransferase
US7425436B2 (en) 2004-07-30 2008-09-16 Promega Corporation Covalent tethering of functional groups to proteins and substrates therefor
US7825096B2 (en) 2004-09-08 2010-11-02 The United States Of America As Represented By The Department Of Health And Human Services O6-alkylguanine-DNA alkyltransferase inactivators and beta-glucuronidase cleavable prodrugs
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WO2006114409A1 (en) * 2005-04-27 2006-11-02 Covalys Biosciences Ag Pyrimidines reacting with o6-alkylguanine-dna alkyltransferase
FR2890174B1 (fr) 2005-08-30 2009-04-24 Cis Bio Internat Sa Procede pour la mise en evidence d'un processus biologique par mesure d'un fret
FR2890446B1 (fr) 2005-09-05 2008-04-18 Cis Bio Internat Sa Methode de detection d'interaction intracellulaire entre bio-molecules
CA2656192C (en) 2006-06-30 2016-05-03 Ambit Biosciences Corporation Detectable nucleic acid tag
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US7897737B2 (en) 2006-12-05 2011-03-01 Lasergen, Inc. 3′-OH unblocked, nucleotides and nucleosides, base modified with photocleavable, terminating groups and methods for their use in DNA sequencing
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EP1978093A1 (en) * 2007-04-04 2008-10-08 Ecole Polytechnique Fédérale de Lausanne (EPFL) Method of crosslinking two objects of interest
GB0711560D0 (en) * 2007-06-14 2007-07-25 Innova Biosciences Ltd Improvements in or relating to production of conjugates
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EP2093564A1 (en) 2008-02-25 2009-08-26 Technische Universität Dresden Medizinische Fakultät Carl Gustav Carus Method for distinguishing secretory granules of different ages
KR101677772B1 (ko) 2008-06-11 2016-11-18 레이저젠, 인코퍼레이티드 뉴클레오타이드 및 뉴클레오사이드 그리고 시퀀싱에서의 이들의 이용 방법
FR2936245B1 (fr) * 2008-09-23 2012-07-06 Cis Bio Int Nouveaux substrats d'o6-alkylguanine-adn alkyltransferase et ses mutants.
DE112011100297B4 (de) 2010-01-20 2017-08-24 New England Biolabs, Inc. Zusammensetzungen, Verfahren und damit in Zusammenhang stehende Anwendungen zum Spalten modifizierter DNA
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MX342195B (es) 2011-09-13 2016-09-20 Lasergen Inc Nucleótidos de terminación de rápida fotodescomposición 5-metoxi, 3' -oh no bloqueados y métodos para secuenciación de ácido nucleico.
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US9200260B2 (en) 2012-03-15 2015-12-01 New England Biolabs, Inc. Compositions and methods for the transfer of a hexosamine to a modified nucleotide in a nucleic acid
JP6441893B2 (ja) 2013-03-19 2018-12-19 ディレクティド・ジェノミクス・エル・エル・シー 標的配列の濃縮
JP5781589B2 (ja) * 2013-12-20 2015-09-24 レーザーゲン インコーポレイテッド 光開裂性標識ヌクレオチドとヌクレオシドおよび標識ヌクレオチドとヌクレオシドならびにdna配列決定におけるそれらの使用法
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CN104844710B (zh) * 2015-04-13 2018-02-02 西北大学 定向固定化pega复合型树酯的制备方法及应用
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Citations (1)

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Publication number Priority date Publication date Assignee Title
DE19903895A1 (de) * 1999-02-01 2000-08-03 Kai Johnsson Selektive Immobilisierung und Nachweis der O·6·-Alkylguanin-DNA-Alkyltransferase in der aktiven Form

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Also Published As

Publication number Publication date
US8367361B2 (en) 2013-02-05
WO2002083937A2 (en) 2002-10-24
NZ540410A (en) 2006-06-30
EP2211177B1 (en) 2014-07-16
EP2037271A1 (en) 2009-03-18
US20110201514A1 (en) 2011-08-18
CN1527941A (zh) 2004-09-08
CN1975422A (zh) 2007-06-06
CN1295510C (zh) 2007-01-17
EP1696234A1 (en) 2006-08-30
CA2443570A1 (en) 2002-10-24
CN1975422B (zh) 2012-09-05
EP1410023B1 (en) 2006-06-21
JP4195815B2 (ja) 2008-12-17
IL157880A0 (en) 2004-03-28
ATE482395T1 (de) 2010-10-15
JP2008154587A (ja) 2008-07-10
JP2004532028A (ja) 2004-10-21
KR20040039194A (ko) 2004-05-10
ATE331220T1 (de) 2006-07-15
DE60212642T2 (de) 2007-06-14
ATE419378T1 (de) 2009-01-15
NZ537939A (en) 2005-08-26
EP2211177A1 (en) 2010-07-28
HK1068406A1 (en) 2005-04-29
DK1410023T3 (da) 2006-10-09
US7939284B2 (en) 2011-05-10
DE60237792D1 (de) 2010-11-04
EP1696234B1 (en) 2008-12-31
US20040115130A1 (en) 2004-06-17
DE60230689D1 (de) 2009-02-12
ZA200307442B (en) 2004-06-30
WO2002083937A3 (en) 2004-02-26
EP1410023A2 (en) 2004-04-21
DE60212642D1 (de) 2006-08-03
NZ528594A (en) 2005-07-29
JP4226053B2 (ja) 2009-02-18
EP2037271B1 (en) 2010-09-22

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