AU2002219944B2 - Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment - Google Patents

Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment Download PDF

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Publication number
AU2002219944B2
AU2002219944B2 AU2002219944A AU2002219944A AU2002219944B2 AU 2002219944 B2 AU2002219944 B2 AU 2002219944B2 AU 2002219944 A AU2002219944 A AU 2002219944A AU 2002219944 A AU2002219944 A AU 2002219944A AU 2002219944 B2 AU2002219944 B2 AU 2002219944B2
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AU
Australia
Prior art keywords
seq
amino acid
antibody
rsv
acid sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU2002219944A
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English (en)
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AU2002219944A1 (en
Inventor
William Huse
Leslie S. Johnson
Scott Koenig
Jeffry Watkins
Herren Wu
James F. Young
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MedImmune LLC
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MedImmune LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/724,531 external-priority patent/US7229619B1/en
Application filed by MedImmune LLC filed Critical MedImmune LLC
Publication of AU2002219944A1 publication Critical patent/AU2002219944A1/en
Priority to AU2006203134A priority Critical patent/AU2006203134B2/en
Assigned to MEDIMMUNE, INC reassignment MEDIMMUNE, INC Request for Assignment Assignors: Medimmune,inc
Application granted granted Critical
Publication of AU2002219944B2 publication Critical patent/AU2002219944B2/en
Priority to AU2008202076A priority patent/AU2008202076B2/en
Assigned to MEDIMMUNE, LLC reassignment MEDIMMUNE, LLC Alteration of Name(s) in Register under S187 Assignors: MEDIMMUNE, INC
Priority to AU2010202006A priority patent/AU2010202006B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/11—Paramyxoviridae (F); Pneumoviridae (F), e.g. respiratory syncytial virus [RSV]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • AIDS & HIV (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
AU2002219944A 2000-01-27 2001-11-28 Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment Expired AU2002219944B2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2006203134A AU2006203134B2 (en) 2000-01-27 2006-07-21 Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
AU2008202076A AU2008202076B2 (en) 2000-11-28 2008-05-09 Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
AU2010202006A AU2010202006B2 (en) 2000-01-27 2010-05-18 Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US72439600A 2000-11-28 2000-11-28
US09/724,531 US7229619B1 (en) 2000-11-28 2000-11-28 Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
US09/724,531 2000-11-28
US09/724,396 2000-11-28
PCT/US2001/044807 WO2002043660A2 (en) 2000-11-28 2001-11-28 Methods of administering/dosing anti-rsv antibodies for prophylaxis and treatment

Related Child Applications (2)

Application Number Title Priority Date Filing Date
AU2006203134A Division AU2006203134B2 (en) 2000-01-27 2006-07-21 Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
AU2008202076A Division AU2008202076B2 (en) 2000-11-28 2008-05-09 Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment

Publications (2)

Publication Number Publication Date
AU2002219944A1 AU2002219944A1 (en) 2002-08-15
AU2002219944B2 true AU2002219944B2 (en) 2008-02-21

Family

ID=27110973

Family Applications (4)

Application Number Title Priority Date Filing Date
AU2002219944A Expired AU2002219944B2 (en) 2000-01-27 2001-11-28 Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
AU1994402A Pending AU1994402A (en) 2000-11-28 2001-11-28 Methods of administering/dosing anti-rsv antibodies for prophylaxis and treatment
AU2006203134A Ceased AU2006203134B2 (en) 2000-01-27 2006-07-21 Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
AU2010202006A Ceased AU2010202006B2 (en) 2000-01-27 2010-05-18 Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment

Family Applications After (3)

Application Number Title Priority Date Filing Date
AU1994402A Pending AU1994402A (en) 2000-11-28 2001-11-28 Methods of administering/dosing anti-rsv antibodies for prophylaxis and treatment
AU2006203134A Ceased AU2006203134B2 (en) 2000-01-27 2006-07-21 Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
AU2010202006A Ceased AU2010202006B2 (en) 2000-01-27 2010-05-18 Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment

Country Status (6)

Country Link
EP (4) EP2412384A1 (https=)
JP (3) JP4434580B2 (https=)
AU (4) AU2002219944B2 (https=)
CA (1) CA2430039C (https=)
TW (2) TWI327599B (https=)
WO (1) WO2002043660A2 (https=)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7635568B2 (en) 2000-11-28 2009-12-22 Medimmune, Llc Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
US7700735B2 (en) 2000-03-01 2010-04-20 Medimmune, Llc High potency recombinant antibodies and method for producing them
US7740851B2 (en) 2000-01-27 2010-06-22 Medimmune, Llc Ultra high affinity neutralizing antibodies
US7785592B2 (en) 2002-06-14 2010-08-31 Medimmune, Llc Stabilized liquid anti-RSV antibody formulations
US7847082B2 (en) 2000-11-28 2010-12-07 Medimmune, Llc Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
US8562996B2 (en) 2007-06-01 2013-10-22 Medimmune Limited RSV-specific binding molecules and means for producing them
US8568726B2 (en) 2009-10-06 2013-10-29 Medimmune Limited RSV specific binding molecule
WO2022258068A1 (zh) * 2021-06-11 2022-12-15 中国科学院微生物研究所 一种呼吸道合胞病毒的抗体及其应用

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EP2412384A1 (en) * 2000-11-28 2012-02-01 MedImmune, LLC Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
US7425618B2 (en) * 2002-06-14 2008-09-16 Medimmune, Inc. Stabilized anti-respiratory syncytial virus (RSV) antibody formulations
US9028822B2 (en) 2002-06-28 2015-05-12 Domantis Limited Antagonists against TNFR1 and methods of use therefor
AU2003232081B2 (en) * 2002-07-03 2009-02-05 Brandeis University Central airway administration for systemic delivery of therapeutics
WO2004010935A2 (en) * 2002-07-25 2004-02-05 Medimmune, Inc. Methods of treating and preventing rsv, hmpv, and piv using anti-rsv, anti-hmpv, and anti-piv antibodies
JP4764818B2 (ja) 2003-04-11 2011-09-07 メディミューン，エルエルシー 組換えｉｌ−９抗体およびその使用
EP1755673B1 (en) 2004-04-12 2014-07-23 MedImmune, LLC Anti-il-9 antibody formulations and uses thereof
AU2005302453A1 (en) * 2004-10-29 2006-05-11 Medimmune, Llc Methods of preventing and treating RSV infections and related conditions
GB0521621D0 (en) * 2005-10-24 2005-11-30 Domantis Ltd Tumor necrosis factor receptor 1 antagonists for treating respiratory diseases
EP1893647A2 (en) 2005-06-23 2008-03-05 MedImmune, Inc. Antibody formulations having optimized aggregation and fragmentation profiles
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CA2688433A1 (en) 2007-06-06 2008-12-11 Domantis Limited Methods for selecting protease resistant polypeptides
PH12012502244A1 (en) * 2010-07-09 2016-09-30 Crucell Holland Bv Anti-human respiratory syncytial virus (rsv) antibodies and methods of use
ES2683169T3 (es) 2013-06-21 2018-09-25 Alfresa Pharma Corporation Dispositivo de inmunocromatografía para detectar el VRS
WO2017100540A2 (en) 2015-12-09 2017-06-15 The California Institute For Biomedical Research Relaxin immunoglobulin fusion proteins and methods of use
EP3630162A1 (en) * 2017-05-24 2020-04-08 Novartis AG Antibody-cytokine engrafted proteins and methods of use

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