AU2001284934A1 - Steroid derived antibiotics - Google Patents

Steroid derived antibiotics

Info

Publication number
AU2001284934A1
AU2001284934A1 AU2001284934A AU8493401A AU2001284934A1 AU 2001284934 A1 AU2001284934 A1 AU 2001284934A1 AU 2001284934 A AU2001284934 A AU 2001284934A AU 8493401 A AU8493401 A AU 8493401A AU 2001284934 A1 AU2001284934 A1 AU 2001284934A1
Authority
AU
Australia
Prior art keywords
derived antibiotics
steroid derived
steroid
antibiotics
derived
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001284934A
Other languages
English (en)
Inventor
Chunchong Li
Paul B. Savage
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Brigham Young University
Original Assignee
Brigham Young University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brigham Young University filed Critical Brigham Young University
Publication of AU2001284934A1 publication Critical patent/AU2001284934A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0088Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing unsubstituted amino radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2001284934A 2000-08-15 2001-08-15 Steroid derived antibiotics Abandoned AU2001284934A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22546700P 2000-08-15 2000-08-15
US60225467 2000-08-15
PCT/US2001/025532 WO2002014342A1 (en) 2000-08-15 2001-08-15 Steroid derived antibiotics

Publications (1)

Publication Number Publication Date
AU2001284934A1 true AU2001284934A1 (en) 2002-02-25

Family

ID=22844981

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001284934A Abandoned AU2001284934A1 (en) 2000-08-15 2001-08-15 Steroid derived antibiotics

Country Status (5)

Country Link
EP (1) EP1311531B1 (cg-RX-API-DMAC7.html)
JP (1) JP5052730B2 (cg-RX-API-DMAC7.html)
AU (1) AU2001284934A1 (cg-RX-API-DMAC7.html)
CA (1) CA2419801C (cg-RX-API-DMAC7.html)
WO (1) WO2002014342A1 (cg-RX-API-DMAC7.html)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5098015B2 (ja) * 2005-01-13 2012-12-12 国立大学法人 名古屋工業大学 菌体膜傷害性・抗菌性物質とその利用方法
CZ300722B6 (cs) * 2006-09-27 2009-07-22 Univerzita Karlova v Praze, Prírodovedecká fakulta Zpusob prípravy inkluzního komplexu pentacyklických a tetracyklických terpenoidu a farmaceutického prostredku obsahujícího tento inkluzní komplex, inkluzní komplex pentacyklického nebo tetracyklického terpenoidu a farmaceutický prostredek obsahující
WO2010036427A1 (en) 2008-06-17 2010-04-01 Brigham Young University Cationic steroid antimicrobial diagnostic, detection, screening and imaging methods
CN103313597B (zh) * 2010-11-03 2016-06-29 布莱阿姆青年大学 结合吸水性聚合物和塞拉集宁化合物的制品
CN104053458B (zh) * 2011-07-20 2016-07-20 布莱阿姆青年大学 包含洗脱塞拉集宁化合物的水凝胶材料
US8932614B2 (en) 2011-08-25 2015-01-13 Paul B. Savage Incorporation of particulate ceragenins in polymers
US9694019B2 (en) 2011-09-13 2017-07-04 Brigham Young University Compositions and methods for treating bone diseases and broken bones
US9603859B2 (en) 2011-09-13 2017-03-28 Brigham Young University Methods and products for increasing the rate of healing of tissue wounds
MX369385B (es) 2011-09-13 2019-11-07 Univ Brigham Young Productos para cicatrizar heridas tisulares.
JP6038154B2 (ja) 2011-09-13 2016-12-07 ブリガム・ヤング・ユニバーシティBrigham Young University 骨疾患および破断骨治療のための組成物
BR112014015144B1 (pt) * 2011-12-21 2018-03-27 Brigham Young University Composição aquosa para cuidado oral, uso de um composto esteroide catiônico e método não- terapêutico de redução de compostos voláteis de enxofre
EP2819531B1 (en) * 2012-03-01 2016-01-20 Brigham Young University Anti-microbial food processing compositions including ceragenin compounds and methods of use
US9533063B1 (en) 2012-03-01 2017-01-03 Brigham Young University Aerosols incorporating ceragenin compounds and methods of use thereof
US20130280391A1 (en) * 2012-04-24 2013-10-24 Brigham Young University Anti-microbial wash compositions including ceragenin compounds and methods of use for treating non-meat food products
CA2872399C (en) * 2012-05-02 2021-01-12 Brigham Young University Ceragenin particulate materials and methods for making same
WO2014062960A1 (en) 2012-10-17 2014-04-24 Brigham Young University Treatment and prevention of mastitis
WO2014107740A2 (en) 2013-01-07 2014-07-10 Brigham Young University Methods for reducing cellular proliferation and treating certain diseases
US11524015B2 (en) 2013-03-15 2022-12-13 Brigham Young University Methods for treating inflammation, autoimmune disorders and pain
US10568893B2 (en) 2013-03-15 2020-02-25 Brigham Young University Methods for treating inflammation, autoimmune disorders and pain
WO2014151411A1 (en) 2013-03-15 2014-09-25 Brigham Young University Methods for treating inflammation, autoimmune disorders and pain
US9387215B2 (en) * 2013-04-22 2016-07-12 Brigham Young University Animal feed including cationic cholesterol additive and related methods
US11690855B2 (en) 2013-10-17 2023-07-04 Brigham Young University Methods for treating lung infections and inflammation
US10000527B2 (en) 2013-12-12 2018-06-19 Council Of Scientific And Industrial Research 11-substituted bile acid derivatives, process for the preparation thereof and use of these compounds as medicaments
US20150203527A1 (en) 2014-01-23 2015-07-23 Brigham Young University Cationic steroidal antimicrobials
CA2844321C (en) 2014-02-27 2021-03-16 Brigham Young University Cationic steroidal antimicrobial compounds
US10220045B2 (en) 2014-03-13 2019-03-05 Brigham Young University Compositions and methods for forming stabilized compositions with reduced CSA agglomeration
US9867836B2 (en) 2014-03-13 2018-01-16 Brigham Young University Lavage and/or infusion using CSA compounds for increasing fertility in a mammal
US9931350B2 (en) 2014-03-14 2018-04-03 Brigham Young University Anti-infective and osteogenic compositions and methods of use
US9686966B2 (en) 2014-04-30 2017-06-27 Brigham Young University Methods and apparatus for cleaning or disinfecting a water delivery system
US10238665B2 (en) 2014-06-26 2019-03-26 Brigham Young University Methods for treating fungal infections
US10441595B2 (en) 2014-06-26 2019-10-15 Brigham Young University Methods for treating fungal infections
US10227376B2 (en) 2014-08-22 2019-03-12 Brigham Young University Radiolabeled cationic steroid antimicrobials and diagnostic methods
US10155788B2 (en) 2014-10-07 2018-12-18 Brigham Young University Cationic steroidal antimicrobial prodrug compositions and uses thereof
WO2016172543A1 (en) 2015-04-22 2016-10-27 Savage Paul B Methods for the synthesis of ceragenins
WO2016172553A1 (en) 2015-04-22 2016-10-27 Savage Paul B Methods for the synthesis of ceragenins
US9434759B1 (en) 2015-05-18 2016-09-06 Brigham Young University Cationic steroidal antimicrobial compounds and methods of manufacturing such compounds
US10226550B2 (en) 2016-03-11 2019-03-12 Brigham Young University Cationic steroidal antimicrobial compositions for the treatment of dermal tissue
JP2017031201A (ja) * 2016-09-30 2017-02-09 ブリガム ヤング ユニバーシティ 口腔ケア組成物
US10959433B2 (en) 2017-03-21 2021-03-30 Brigham Young University Use of cationic steroidal antimicrobials for sporicidal activity
US12186328B2 (en) 2019-05-23 2025-01-07 Brigham Young University Use of CSA compounds to stimulate stem cells and hair growth
US12454547B2 (en) 2022-04-22 2025-10-28 Asteroid Therapeutics Steroidal compositions and methods of treating lipogenic cancers

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1556099A (en) * 1997-12-12 1999-07-05 Novo Nordisk A/S Cholic acid-based scaffolds for multidimensional molecular presentation of peptides
EP1058552B1 (en) * 1998-03-06 2004-06-16 Brigham Young University Steroid derived antibiotics
US6350738B1 (en) * 1998-03-06 2002-02-26 Brigham Young University Steroid derived antibiotics

Also Published As

Publication number Publication date
CA2419801A1 (en) 2002-02-21
JP2004506645A (ja) 2004-03-04
EP1311531A1 (en) 2003-05-21
EP1311531B1 (en) 2016-05-11
JP5052730B2 (ja) 2012-10-17
WO2002014342A1 (en) 2002-02-21
CA2419801C (en) 2010-08-10
EP1311531A4 (en) 2009-10-28

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