AU2001281930A1 - Method for detecting pre-disposition to hepatotoxicity - Google Patents

Method for detecting pre-disposition to hepatotoxicity

Info

Publication number
AU2001281930A1
AU2001281930A1 AU2001281930A AU8193001A AU2001281930A1 AU 2001281930 A1 AU2001281930 A1 AU 2001281930A1 AU 2001281930 A AU2001281930 A AU 2001281930A AU 8193001 A AU8193001 A AU 8193001A AU 2001281930 A1 AU2001281930 A1 AU 2001281930A1
Authority
AU
Australia
Prior art keywords
hepatotoxicity
disposition
detecting pre
detecting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001281930A
Other languages
English (en)
Inventor
Gonzalo Acuna
Dorothee Foernzler
Diane Uratsu Leong
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of AU2001281930A1 publication Critical patent/AU2001281930A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU2001281930A 2000-07-14 2001-07-02 Method for detecting pre-disposition to hepatotoxicity Abandoned AU2001281930A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP00115353.5 2000-07-14
EP00115353 2000-07-14
PCT/EP2001/007524 WO2002006523A2 (en) 2000-07-14 2001-07-02 Method for detecting pre-disposition to hepatotoxicity

Publications (1)

Publication Number Publication Date
AU2001281930A1 true AU2001281930A1 (en) 2002-01-30

Family

ID=8169277

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001281930A Abandoned AU2001281930A1 (en) 2000-07-14 2001-07-02 Method for detecting pre-disposition to hepatotoxicity

Country Status (5)

Country Link
US (1) US20040076968A1 (https=)
EP (1) EP1325152A2 (https=)
JP (1) JP3947103B2 (https=)
AU (1) AU2001281930A1 (https=)
WO (1) WO2002006523A2 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6395481B1 (en) * 1999-02-16 2002-05-28 Arch Development Corp. Methods for detection of promoter polymorphism in a UGT gene promoter
US20030099960A1 (en) * 2001-01-26 2003-05-29 The University Of Chicago Compositions and methods for optimizing UGT2B7 substrate dosings and for predicting UGT2B7 substrate toxicity
DE10207971A1 (de) * 2002-02-25 2003-09-11 Norbert Dahmen Verfahren zur Identifizierung Nebenwirkungs-relevanter Markerprofile
AU2003228425A1 (en) * 2002-04-01 2003-10-20 Phase-1 Molecular Toxicology, Inc. Liver necrosis predictive genes
US20040203034A1 (en) * 2003-01-03 2004-10-14 The University Of Chicago Optimization of cancer treatment with irinotecan
ES2308208T3 (es) 2003-05-30 2008-12-01 University Of Chicago Metodos y composiciones para predecir la toxicidad del irinotecano.
US20090247475A1 (en) * 2004-03-05 2009-10-01 The Regents Of The University Of California Methods and compositions relating to pharmacogenetics of different gene variants in the context of irinotecan-based therapies
WO2006027182A1 (en) * 2004-09-06 2006-03-16 Medizinische Hochschule Hannover Methods and its kits based on ugt1a7 promoter polymorphism
WO2006070666A1 (ja) * 2004-12-28 2006-07-06 Takara Bio Inc. 遺伝子多型の同時検出方法
EP1790343A1 (en) * 2005-11-11 2007-05-30 Emotional Brain B.V. Pharmaceuticals formulations and uses thereof in the treatment of female sexual dysfunction
CN106755388B (zh) * 2016-11-24 2019-08-23 厦门艾德生物医药科技股份有限公司 一种改进的ARMS引物结构(Super-ARMS)及其使用方法
CN108315420A (zh) * 2018-04-04 2018-07-24 广西中医药大学附属瑞康医院 一种用于检测乙肝癌变多态性的试剂盒

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992012987A1 (en) 1991-01-10 1992-08-06 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services The genetic locus ugt1 and a mutation therein
TW221441B (https=) 1991-01-25 1994-03-01 Taiho Pharmaceutical Co Ltd
JP2000508912A (ja) 1996-04-19 2000-07-18 スペクトラ バイオメディカル，インコーポレイテッド 多型形態と複数の表現型との相関付け
GB2321190B (en) * 1997-01-16 2000-09-20 Britannia Pharmaceuticals Ltd Pharmaceutical composition
EP1084271A2 (en) * 1998-05-07 2001-03-21 Axys Pharmaceuticals, Inc. Genotyping the human udp-glucuronosyltransferase 1 (ugt1) gene

Also Published As

Publication number Publication date
WO2002006523A2 (en) 2002-01-24
JP2004508017A (ja) 2004-03-18
EP1325152A2 (en) 2003-07-09
JP3947103B2 (ja) 2007-07-18
WO2002006523A3 (en) 2003-04-17
US20040076968A1 (en) 2004-04-22

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