AU2001281255B2 - Substituted pyrazoles - Google Patents

Substituted pyrazoles Download PDF

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Publication number
AU2001281255B2
AU2001281255B2 AU2001281255A AU2001281255A AU2001281255B2 AU 2001281255 B2 AU2001281255 B2 AU 2001281255B2 AU 2001281255 A AU2001281255 A AU 2001281255A AU 2001281255 A AU2001281255 A AU 2001281255A AU 2001281255 B2 AU2001281255 B2 AU 2001281255B2
Authority
AU
Australia
Prior art keywords
phenyl
piperazin
pyrazolo
tetrahydro
propyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU2001281255A
Other languages
English (en)
Other versions
AU2001281255A1 (en
Inventor
J. Guy Breitenbucher
Hui Cai
James P. Edwards
Cheryl A. Grice
Darin J. Gustin
Haripada Khatuya
Steven P. Meduna
Barbara A. Pio
Kevin L. Tays
Jianmei Wei
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceuticals Inc
Original Assignee
Ortho McNeil Pharmaceutical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho McNeil Pharmaceutical Inc filed Critical Ortho McNeil Pharmaceutical Inc
Publication of AU2001281255A1 publication Critical patent/AU2001281255A1/en
Application granted granted Critical
Publication of AU2001281255B2 publication Critical patent/AU2001281255B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
AU2001281255A 2000-08-14 2001-08-10 Substituted pyrazoles Expired AU2001281255B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US22513800P 2000-08-14 2000-08-14
US60/225,138 2000-08-14
US09/928,122 2001-08-10
PCT/US2001/025289 WO2002014314A2 (en) 2000-08-14 2001-08-10 Substituted pyrazoles
US09/928,122 US7309703B2 (en) 2000-08-14 2001-08-10 Substituted pyrazoles

Publications (2)

Publication Number Publication Date
AU2001281255A1 AU2001281255A1 (en) 2002-05-23
AU2001281255B2 true AU2001281255B2 (en) 2006-07-20

Family

ID=26919335

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2001281255A Expired AU2001281255B2 (en) 2000-08-14 2001-08-10 Substituted pyrazoles
AU8125501A Pending AU8125501A (en) 2000-08-14 2001-08-10 Substituted pyrazoles

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU8125501A Pending AU8125501A (en) 2000-08-14 2001-08-10 Substituted pyrazoles

Country Status (17)

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US (9) US7589202B2 (US07772236-20100810-C00037.png)
EP (1) EP1309591B1 (US07772236-20100810-C00037.png)
JP (1) JP5140225B2 (US07772236-20100810-C00037.png)
CN (1) CN1329392C (US07772236-20100810-C00037.png)
AR (1) AR035714A1 (US07772236-20100810-C00037.png)
AT (1) ATE352552T1 (US07772236-20100810-C00037.png)
AU (2) AU2001281255B2 (US07772236-20100810-C00037.png)
CA (1) CA2419540A1 (US07772236-20100810-C00037.png)
CY (1) CY1106032T1 (US07772236-20100810-C00037.png)
DE (1) DE60126286T2 (US07772236-20100810-C00037.png)
DK (1) DK1309591T3 (US07772236-20100810-C00037.png)
ES (1) ES2281434T3 (US07772236-20100810-C00037.png)
HK (1) HK1052509B (US07772236-20100810-C00037.png)
MX (1) MXPA03001421A (US07772236-20100810-C00037.png)
NZ (1) NZ524193A (US07772236-20100810-C00037.png)
PT (1) PT1309591E (US07772236-20100810-C00037.png)
WO (1) WO2002014314A2 (US07772236-20100810-C00037.png)

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Also Published As

Publication number Publication date
JP5140225B2 (ja) 2013-02-06
JP2004512272A (ja) 2004-04-22
CN1468239A (zh) 2004-01-14
WO2002014314A2 (en) 2002-02-21
DE60126286D1 (de) 2007-03-15
AU8125501A (en) 2002-02-25
DE60126286T2 (de) 2007-11-15
MXPA03001421A (es) 2004-01-26
US7429591B2 (en) 2008-09-30
US20070004738A1 (en) 2007-01-04
US20070021437A1 (en) 2007-01-25
CY1106032T1 (el) 2011-04-06
US20070004755A1 (en) 2007-01-04
US7309703B2 (en) 2007-12-18
US7388011B2 (en) 2008-06-17
US7452890B2 (en) 2008-11-18
EP1309591A2 (en) 2003-05-14
AR035714A1 (es) 2004-07-07
US7417046B2 (en) 2008-08-26
DK1309591T3 (da) 2007-03-26
CN1329392C (zh) 2007-08-01
EP1309591B1 (en) 2007-01-24
US7772236B2 (en) 2010-08-10
US20020040020A1 (en) 2002-04-04
US20070010530A1 (en) 2007-01-11
HK1052509A1 (en) 2003-09-19
WO2002014314A3 (en) 2002-06-06
US20070004747A1 (en) 2007-01-04
NZ524193A (en) 2004-12-24
PT1309591E (pt) 2007-04-30
US20080293732A1 (en) 2008-11-27
ES2281434T3 (es) 2007-10-01
US20070004754A1 (en) 2007-01-04
HK1052509B (zh) 2007-09-07
US7589202B2 (en) 2009-09-15
US7393850B2 (en) 2008-07-01
US20080300255A1 (en) 2008-12-04
CA2419540A1 (en) 2002-02-21
ATE352552T1 (de) 2007-02-15

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