AU2001281076A1 - Fluidic mixer in microfluidic system - Google Patents

Fluidic mixer in microfluidic system

Info

Publication number
AU2001281076A1
AU2001281076A1 AU2001281076A AU8107601A AU2001281076A1 AU 2001281076 A1 AU2001281076 A1 AU 2001281076A1 AU 2001281076 A AU2001281076 A AU 2001281076A AU 8107601 A AU8107601 A AU 8107601A AU 2001281076 A1 AU2001281076 A1 AU 2001281076A1
Authority
AU
Australia
Prior art keywords
microfluidic system
fluidic mixer
fluidic
mixer
microfluidic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001281076A
Other languages
English (en)
Inventor
Christoph Karp
Stephen D. O'connor
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nanostream Inc
Original Assignee
Nanostream Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanostream Inc filed Critical Nanostream Inc
Publication of AU2001281076A1 publication Critical patent/AU2001281076A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D17/00—Separation of liquids, not provided for elsewhere, e.g. by thermal diffusion
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D17/00—Separation of liquids, not provided for elsewhere, e.g. by thermal diffusion
    • B01D17/02—Separation of non-miscible liquids
    • B01D17/0208—Separation of non-miscible liquids by sedimentation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D17/00—Separation of liquids, not provided for elsewhere, e.g. by thermal diffusion
    • B01D17/08—Thickening liquid suspensions by filtration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/421—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions by moving the components in a convoluted or labyrinthine path
    • B01F25/422—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions by moving the components in a convoluted or labyrinthine path between stacked plates, e.g. grooved or perforated plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
    • B81B1/00—Devices without movable or flexible elements, e.g. microcapillary devices
    • B81B1/002—Holes characterised by their shape, in either longitudinal or sectional plane
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0874—Three dimensional network
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
    • B01L2300/165—Specific details about hydrophobic, oleophobic surfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
    • B81B2201/00—Specific applications of microelectromechanical systems
    • B81B2201/05—Microfluidics
    • B81B2201/051—Micromixers, microreactors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00178—Special arrangements of analysers
    • G01N2035/00237—Handling microquantities of analyte, e.g. microvalves, capillary networks
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465—Separating and mixing arrangements
    • G01N2035/00534—Mixing by a special element, e.g. stirrer
    • G01N2035/00544—Mixing by a special element, e.g. stirrer using fluid flow
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/206—Flow affected by fluid contact, energy field or coanda effect [e.g., pure fluid device or system]
    • Y10T137/218—Means to regulate or vary operation of device
    • Y10T137/2191—By non-fluid energy field affecting input [e.g., transducer]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/206—Flow affected by fluid contact, energy field or coanda effect [e.g., pure fluid device or system]
    • Y10T137/2224—Structure of body of device
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/794—With means for separating solid material from the fluid
    • Y10T137/8122—Planar strainer normal to flow path
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/24—Structurally defined web or sheet [e.g., overall dimension, etc.]
    • Y10T428/24479—Structurally defined web or sheet [e.g., overall dimension, etc.] including variation in thickness
    • Y10T428/24562—Interlaminar spaces
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/24—Structurally defined web or sheet [e.g., overall dimension, etc.]
    • Y10T428/24744—Longitudinal or transverse tubular cavity or cell
AU2001281076A 2000-08-07 2001-08-03 Fluidic mixer in microfluidic system Abandoned AU2001281076A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US63268100A 2000-08-07 2000-08-07
US09/632,681 2000-08-07
PCT/US2001/024521 WO2002011888A2 (fr) 2000-08-07 2001-08-03 Melangeur fluidique pour systeme microfluidique

Publications (1)

Publication Number Publication Date
AU2001281076A1 true AU2001281076A1 (en) 2002-02-18

Family

ID=24536489

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001281076A Abandoned AU2001281076A1 (en) 2000-08-07 2001-08-03 Fluidic mixer in microfluidic system

Country Status (4)

Country Link
US (2) US6676835B2 (fr)
EP (1) EP1309404A2 (fr)
AU (1) AU2001281076A1 (fr)
WO (1) WO2002011888A2 (fr)

Families Citing this family (165)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6890093B2 (en) * 2000-08-07 2005-05-10 Nanostream, Inc. Multi-stream microfludic mixers
EP1322947B1 (fr) * 2000-09-07 2007-12-12 GeSIM Gesellschaft für Silizium-Mikrosysteme mbH Procede pour la production d'une microcuve a circulation tridimensionnelle et microcuve a circulation tridimensionnelle
US20050032204A1 (en) * 2001-04-10 2005-02-10 Bioprocessors Corp. Microreactor architecture and methods
FR2823995B1 (fr) * 2001-04-25 2008-06-06 Alfa Laval Vicarb Dispositif perfectionne d'echange et/ou de reaction entre fluides
US6814938B2 (en) * 2001-05-23 2004-11-09 Nanostream, Inc. Non-planar microfluidic devices and methods for their manufacture
JP3694877B2 (ja) * 2001-05-28 2005-09-14 株式会社山武 マイクロ混合器
US7128876B2 (en) * 2001-07-17 2006-10-31 Agilent Technologies, Inc. Microdevice and method for component separation in a fluid
GB2380528B (en) * 2001-10-05 2003-09-10 Minebea Co Ltd A bearing assembly and method of manufacturing a bearing assembly
DE10150549A1 (de) * 2001-10-12 2003-04-17 Roche Diagnostics Gmbh Verfahren und Trennmodul zum Abtrennen von Partikeln aus einer Dispersion, insbesondere von Blutkörperchen aus Blut
US7069952B1 (en) 2001-11-14 2006-07-04 Caliper Life Sciences, Inc. Microfluidic devices and methods of their manufacture
US20030098661A1 (en) * 2001-11-29 2003-05-29 Ken Stewart-Smith Control system for vehicle seats
AU2002351291A1 (en) * 2001-12-06 2003-06-23 Nanostream, Inc. Adhesiveless microfluidic device fabrication
US6845787B2 (en) * 2002-02-23 2005-01-25 Nanostream, Inc. Microfluidic multi-splitter
US7223371B2 (en) 2002-03-14 2007-05-29 Micronics, Inc. Microfluidic channel network device
GB0208766D0 (en) * 2002-04-02 2002-05-29 Univ Surrey Liquid-liquid separation
US7517440B2 (en) * 2002-07-17 2009-04-14 Eksigent Technologies Llc Electrokinetic delivery systems, devices and methods
US7364647B2 (en) * 2002-07-17 2008-04-29 Eksigent Technologies Llc Laminated flow device
US7235164B2 (en) 2002-10-18 2007-06-26 Eksigent Technologies, Llc Electrokinetic pump having capacitive electrodes
DE10238825A1 (de) * 2002-08-23 2004-03-11 Roche Diagnostics Gmbh Mikrofluidische Systeme mit hohem Aspektverhältnis
JP3824160B2 (ja) * 2002-08-28 2006-09-20 株式会社島津製作所 高速液体クロマトグラフ用混合装置
US6806543B2 (en) * 2002-09-12 2004-10-19 Intel Corporation Microfluidic apparatus with integrated porous-substrate/sensor for real-time (bio)chemical molecule detection
EP1403209A1 (fr) * 2002-09-24 2004-03-31 The Technology Partnership Limited Dispositif d'acheminement de fluide
AU2003284055A1 (en) * 2002-10-09 2004-05-04 The Board Of Trustees Of The University Of Illinois Microfluidic systems and components
US20040112529A1 (en) * 2002-10-09 2004-06-17 Cellectricon Ab Methods for interfacing macroscale components to microscale devices
DE10302720A1 (de) * 2003-01-23 2004-08-05 Steag Microparts Gmbh Mikrofluidischer Schalter zum Anhalten des Flüssigkeitsstroms während eines Zeitintervalls
DE10302721A1 (de) 2003-01-23 2004-08-05 Steag Microparts Gmbh Mikrofluidische Anordnung zum Dosieren von Flüssigkeiten
DE10320870A1 (de) 2003-05-09 2004-12-09 Evotec Technologies Gmbh Partikelinjektor für einen Zellsortierer
US7485671B2 (en) * 2003-05-16 2009-02-03 Velocys, Inc. Process for forming an emulsion using microchannel process technology
CA2526965C (fr) * 2003-05-16 2011-10-11 Velocys Inc. Procede pour former une emulsion par la technique de traitement en microcanal
KR100509254B1 (ko) * 2003-05-22 2005-08-23 한국전자통신연구원 미세 유체의 이송 시간을 제어할 수 있는 미세 유체 소자
JP4348676B2 (ja) * 2003-06-03 2009-10-21 富士フイルム株式会社 マイクロ化学装置
US7344681B1 (en) 2003-06-06 2008-03-18 Sandia Corporation Planar micromixer
WO2005029041A2 (fr) * 2003-09-19 2005-03-31 Applera Corporation Procedes et appareil de detection de sequence haute densite
US20050069949A1 (en) * 2003-09-30 2005-03-31 International Business Machines Corporation Microfabricated Fluidic Structures
US20050069462A1 (en) * 2003-09-30 2005-03-31 International Business Machines Corporation Microfluidics Packaging
US8066955B2 (en) * 2003-10-17 2011-11-29 James M. Pinchot Processing apparatus fabrication
US20050084072A1 (en) * 2003-10-17 2005-04-21 Jmp Industries, Inc., An Ohio Corporation Collimator fabrication
US6994245B2 (en) * 2003-10-17 2006-02-07 James M. Pinchot Micro-reactor fabrication
EP1525917A1 (fr) * 2003-10-23 2005-04-27 F. Hoffmann-La Roche Ag Dispositif microfluidique avec traversée
KR100613398B1 (ko) * 2003-11-25 2006-08-17 한국과학기술연구원 캔틸레버 센서형 분석 시스템, 제조 방법 및 이를 이용한극미세 물질 감지 방법
US20050133437A1 (en) * 2003-12-17 2005-06-23 Intel Corporation Sieving media from planar arrays of nanoscale grooves, method of making and method of using the same
US7582264B2 (en) * 2004-02-17 2009-09-01 Ibidi Gmbh Device for microfluid analyses
US7588724B2 (en) 2004-03-05 2009-09-15 Bayer Healthcare Llc Mechanical device for mixing a fluid sample with a treatment solution
US7507380B2 (en) * 2004-03-19 2009-03-24 State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Microchemical nanofactories
US7559356B2 (en) 2004-04-19 2009-07-14 Eksident Technologies, Inc. Electrokinetic pump driven heat transfer system
AU2005241523A1 (en) * 2004-05-04 2005-11-17 Bayer Healthcare Llc Mechanical cartridge with test strip fluid control features for use in a fluid analyte meter
US7419639B2 (en) * 2004-05-12 2008-09-02 The Board Of Trustees Of The Leland Stanford Junior University Multilayer microfluidic device
US8057740B2 (en) * 2004-06-23 2011-11-15 Tesa Se Medical biosensor by means of which biological liquids are analyzed
US7264206B2 (en) * 2004-09-30 2007-09-04 The Boeing Company Leading edge flap apparatuses and associated methods
EP1804964A1 (fr) 2004-10-01 2007-07-11 Velocys Inc. Procede de melange multiphase par technologie de traitement a micro-canaux
US7955504B1 (en) 2004-10-06 2011-06-07 State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Microfluidic devices, particularly filtration devices comprising polymeric membranes, and method for their manufacture and use
CN101132854B (zh) * 2004-11-16 2011-07-06 万罗赛斯公司 使用微通道技术的多相反应方法
WO2006057895A2 (fr) * 2004-11-17 2006-06-01 Velocys Inc. Procede de formation d'emulsions par la technique des microcanaux
GB2438768A (en) * 2005-02-15 2007-12-05 Univ Singapore Microfluidics package and method of fabricating the same
FR2882939B1 (fr) * 2005-03-11 2007-06-08 Centre Nat Rech Scient Dispositif de separation fluidique
DE102005013916B4 (de) * 2005-03-24 2016-06-09 Leibniz-Institut Für Polymerforschung Dresden E.V. Mikrofluidvorrichtung zur Separation von Emulsionen
US20070021411A1 (en) * 2005-05-11 2007-01-25 Cloyd James C Supersaturated benzodiazepine solutions and their delivery
US20060285433A1 (en) * 2005-06-20 2006-12-21 Jing-Tang Yang Fluidic mixer of serpentine channel incorporated with staggered sudden-expansion and convergent cross sections
US7846489B2 (en) 2005-07-22 2010-12-07 State of Oregon acting by and though the State Board of Higher Education on behalf of Oregon State University Method and apparatus for chemical deposition
US20070047388A1 (en) * 2005-08-25 2007-03-01 Rockwell Scientific Licensing, Llc Fluidic mixing structure, method for fabricating same, and mixing method
DK1957794T3 (da) 2005-11-23 2014-08-11 Eksigent Technologies Llc Elektrokinetiske pumpeudformninger og lægemiddelfremføringssystemer
US8679587B2 (en) * 2005-11-29 2014-03-25 State of Oregon acting by and through the State Board of Higher Education action on Behalf of Oregon State University Solution deposition of inorganic materials and electronic devices made comprising the inorganic materials
US8647590B2 (en) * 2006-03-16 2014-02-11 Agilent Technologies, Inc. Optical detection cell with micro-fluidic chip
US20070218454A1 (en) * 2006-03-16 2007-09-20 Brennen Reid A Optical detection cell for micro-fluidics
JP4686683B2 (ja) * 2006-05-24 2011-05-25 国立大学法人京都大学 血漿分離用マイクロ流路
US7771655B2 (en) * 2006-07-12 2010-08-10 Bayer Healthcare Llc Mechanical device for mixing a fluid sample with a treatment solution
US20080108122A1 (en) * 2006-09-01 2008-05-08 State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon Microchemical nanofactories
US8403557B2 (en) * 2006-09-28 2013-03-26 University Of Washington Micromixer using integrated three-dimensional porous structure
JP2010505393A (ja) * 2006-09-28 2010-02-25 ユニヴァーシティ オブ ワシントン ３ｄマイクロスケールの人工組織モデルシステム
US8247464B2 (en) 2006-09-28 2012-08-21 University Of Washington Method of selective foaming for porous polymeric material
CN101578520B (zh) 2006-10-18 2015-09-16 哈佛学院院长等 基于形成图案的多孔介质的横向流动和穿过生物测定装置、及其制备方法和使用方法
US7867592B2 (en) 2007-01-30 2011-01-11 Eksigent Technologies, Inc. Methods, compositions and devices, including electroosmotic pumps, comprising coated porous surfaces
US20080237044A1 (en) * 2007-03-28 2008-10-02 The Charles Stark Draper Laboratory, Inc. Method and apparatus for concentrating molecules
WO2008130618A1 (fr) 2007-04-19 2008-10-30 The Charles Stark Draper Laboratory, Inc. Procédé et appareil pour séparer des particules, cellules, molécules et matières particulaires
WO2009002447A1 (fr) 2007-06-21 2008-12-31 Gen-Probe Incorporated Instrument et réceptacles pour l'exécution de procédés
US8206025B2 (en) * 2007-08-07 2012-06-26 International Business Machines Corporation Microfluid mixer, methods of use and methods of manufacture thereof
US7837379B2 (en) * 2007-08-13 2010-11-23 The Charles Stark Draper Laboratory, Inc. Devices for producing a continuously flowing concentration gradient in laminar flow
US8251672B2 (en) 2007-12-11 2012-08-28 Eksigent Technologies, Llc Electrokinetic pump with fixed stroke volume
KR100912540B1 (ko) 2007-12-14 2009-08-18 한국전자통신연구원 세척 효과를 개선하기 위한 미세 채널을 형성하는 칩
US8397762B2 (en) * 2008-02-04 2013-03-19 Bioscale, Inc. Fluidic system with improved flow characteristics
US20090211977A1 (en) * 2008-02-27 2009-08-27 Oregon State University Through-plate microchannel transfer devices
EP2266691A4 (fr) * 2008-03-25 2014-04-16 Univ Okayama Nat Univ Corp Dispositif de distribution de microgouttelettes
CN101978272B (zh) * 2008-03-27 2015-02-04 哈佛学院院长等 基于纸的细胞阵列
EP2257818B1 (fr) * 2008-03-27 2017-05-10 President and Fellows of Harvard College Fil de coton servant de plate-forme diagnostique pour analyses multiples à bas coûts
US8921118B2 (en) * 2008-03-27 2014-12-30 President And Fellows Of Harvard College Paper-based microfluidic systems
CN102016595B (zh) * 2008-03-27 2014-08-06 哈佛学院院长等 三维微流体装置
KR101541458B1 (ko) * 2008-07-03 2015-08-04 삼성전자주식회사 유체 혼합 방법 및 유체 혼합 장치
US8764279B2 (en) * 2008-07-18 2014-07-01 3M Innovation Properties Company Y-cross mixers and fluid systems including the same
US8846314B2 (en) 2009-03-03 2014-09-30 The Board Of Trustees Of The Leland Stanford Junior University Isotachophoretic focusing of nucleic acids
US9192933B2 (en) 2009-03-06 2015-11-24 President And Fellows Of Harvard College Microfluidic, electrochemical devices
US8236599B2 (en) 2009-04-09 2012-08-07 State of Oregon acting by and through the State Board of Higher Education Solution-based process for making inorganic materials
US8801922B2 (en) * 2009-06-24 2014-08-12 State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Dialysis system
JP2012531256A (ja) * 2009-06-24 2012-12-10 ステイト オブ オレゴン アクティング バイ アンド スルー ザ ステイト ボード オブ ハイヤー エデュケーション オン ビハーフ オブ オレゴン ステイト ユニバーシティー 透析用マイクロ流体デバイス
US9599407B2 (en) 2009-07-29 2017-03-21 Tokitae Llc System and structure for heating or sterilizing a liquid stream
US9930898B2 (en) * 2009-07-29 2018-04-03 Tokitae Llc Pasteurization system and method
US8753515B2 (en) 2009-12-05 2014-06-17 Home Dialysis Plus, Ltd. Dialysis system with ultrafiltration control
WO2011069110A1 (fr) * 2009-12-05 2011-06-09 Home Dialysis Plus, Ltd. Système de dialyse modulaire
CN102821861B (zh) 2010-02-03 2015-03-25 哈佛大学校长及研究员协会 用于多重测定的装置和方法
DE102010003642A1 (de) * 2010-03-15 2011-09-15 Fresenius Medical Care Deutschland Gmbh Kassette mit einem Sensor zur Bestimmung der Differenz eines ersten und eines zweiten Flüssigkeitsstroms
US9125305B2 (en) * 2010-03-17 2015-09-01 Delta Design, Inc. Devices with pneumatic, hydraulic and electrical components
DE102010018981B3 (de) * 2010-05-03 2011-07-21 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V., 80686 Verfahren zur plasmagestützten Behandlung von Innenflächen eines Hohlkörpers, Fluid-Separator sowie dessen Verwendung
US8580161B2 (en) 2010-05-04 2013-11-12 State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Fluidic devices comprising photocontrollable units
US8501009B2 (en) 2010-06-07 2013-08-06 State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Fluid purification system
WO2012001972A1 (fr) * 2010-06-30 2012-01-05 株式会社メタボスクリーン Puce microchimique, procédé pour la produire et procédé pour l'utiliser
US9004001B2 (en) * 2010-12-17 2015-04-14 Palo Alto Research Center Incorporated Interdigitated finger coextrusion device
US9589692B2 (en) 2010-12-17 2017-03-07 Palo Alto Research Center Incorporated Interdigitated electrode device
US8979511B2 (en) 2011-05-05 2015-03-17 Eksigent Technologies, Llc Gel coupling diaphragm for electrokinetic delivery systems
US9291547B2 (en) * 2011-07-15 2016-03-22 Nanyang Technological University Immersion refractometer
EP2763719B1 (fr) 2011-10-07 2017-08-09 Outset Medical, Inc. Purification de fluide d'échange de chaleur pour un système de dialyse
US10752949B2 (en) 2012-08-14 2020-08-25 10X Genomics, Inc. Methods and systems for processing polynucleotides
MX364957B (es) 2012-08-14 2019-05-15 10X Genomics Inc Composiciones y metodos para microcapsulas.
US10323279B2 (en) 2012-08-14 2019-06-18 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10273541B2 (en) 2012-08-14 2019-04-30 10X Genomics, Inc. Methods and systems for processing polynucleotides
US11591637B2 (en) 2012-08-14 2023-02-28 10X Genomics, Inc. Compositions and methods for sample processing
US10221442B2 (en) 2012-08-14 2019-03-05 10X Genomics, Inc. Compositions and methods for sample processing
US10400280B2 (en) 2012-08-14 2019-09-03 10X Genomics, Inc. Methods and systems for processing polynucleotides
US20150376609A1 (en) 2014-06-26 2015-12-31 10X Genomics, Inc. Methods of Analyzing Nucleic Acids from Individual Cells or Cell Populations
US9701998B2 (en) 2012-12-14 2017-07-11 10X Genomics, Inc. Methods and systems for processing polynucleotides
US9951386B2 (en) 2014-06-26 2018-04-24 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10533221B2 (en) 2012-12-14 2020-01-14 10X Genomics, Inc. Methods and systems for processing polynucleotides
CA2894694C (fr) 2012-12-14 2023-04-25 10X Genomics, Inc. Procedes et systemes pour le traitement de polynucleotides
US9590232B2 (en) 2012-12-27 2017-03-07 Palo Alto Research Center Incorporated Three dimensional co-extruded battery electrodes
US9899669B2 (en) 2012-12-27 2018-02-20 Palo Alto Research Center Incorporated Structures for interdigitated finger co-extrusion
US9337471B2 (en) 2012-12-27 2016-05-10 Palo Alto Research Center Incorporated Co-extrusion print head for multi-layer battery structures
US10923714B2 (en) 2012-12-27 2021-02-16 Palo Alto Research Center Incorporated Structures for interdigitated finger co-extrusion
US9012090B2 (en) 2012-12-27 2015-04-21 Palo Alto Research Center Incorporated Advanced, high power and energy battery electrode manufactured by co-extrusion printing
CA2900481A1 (fr) 2013-02-08 2014-08-14 10X Genomics, Inc. Generation de codes a barres de polynucleotides
US9506934B2 (en) * 2013-04-29 2016-11-29 Honeywell International Inc. Polymer test cartridge mixer for cell lysis
US10800086B2 (en) 2013-08-26 2020-10-13 Palo Alto Research Center Incorporated Co-extrusion of periodically modulated structures
US9751071B2 (en) 2013-12-27 2017-09-05 State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Continuous microwave-assisted segmented flow reactor for high-quality nanocrystal synthesis
AU2015243445B2 (en) 2014-04-10 2020-05-28 10X Genomics, Inc. Fluidic devices, systems, and methods for encapsulating and partitioning reagents, and applications of same
EP3137128B1 (fr) 2014-04-29 2021-02-24 Outset Medical, Inc. Système et procédés de dialyse
US9882200B2 (en) 2014-07-31 2018-01-30 Palo Alto Research Center Incorporated High energy and power Li-ion battery having low stress and long-term cycling capacity
WO2016059874A1 (fr) * 2014-10-14 2016-04-21 アルプス電気株式会社 Dispositif de mélange de fluides
US20160122817A1 (en) 2014-10-29 2016-05-05 10X Genomics, Inc. Methods and compositions for targeted nucleic acid sequencing
US9975122B2 (en) 2014-11-05 2018-05-22 10X Genomics, Inc. Instrument systems for integrated sample processing
SG11201705615UA (en) 2015-01-12 2017-08-30 10X Genomics Inc Processes and systems for preparing nucleic acid sequencing libraries and libraries prepared using same
EP3262188B1 (fr) 2015-02-24 2021-05-05 10X Genomics, Inc. Procédés pour la couverture ciblée de séquences d'acides nucléiques
EP3262407B1 (fr) 2015-02-24 2023-08-30 10X Genomics, Inc. Procédés et systèmes de traitement de cloisonnement
US20160322131A1 (en) 2015-04-29 2016-11-03 Palo Alto Research Center Incoporated Co-extrusion printing of filaments for superconducting wire
US9755221B2 (en) 2015-06-26 2017-09-05 Palo Alto Research Center Incorporated Co-extruded conformal battery separator and electrode
US11071956B2 (en) * 2015-08-17 2021-07-27 Ton Duc Thang University Device and process for a micromixer having a trapezoidal zigzag channel
SG11201804086VA (en) 2015-12-04 2018-06-28 10X Genomics Inc Methods and compositions for nucleic acid analysis
AU2017212754B2 (en) 2016-01-29 2023-06-29 Purigen Biosystems, Inc. Isotachophoresis for purification of nucleic acids
US10107726B2 (en) * 2016-03-16 2018-10-23 Cellmax, Ltd. Collection of suspended cells using a transferable membrane
DE102016108258A1 (de) 2016-05-03 2017-11-09 Plan Optik Ag Phasentrennkammer und Verfahren zur Trennung von zwei Phasen
WO2017197338A1 (fr) 2016-05-13 2017-11-16 10X Genomics, Inc. Systèmes microfluidiques et procédés d'utilisation
EP4039286A1 (fr) 2016-08-19 2022-08-10 Outset Medical, Inc. Système et procédés de dialyse péritonéale
US10550429B2 (en) 2016-12-22 2020-02-04 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10815525B2 (en) 2016-12-22 2020-10-27 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10011872B1 (en) 2016-12-22 2018-07-03 10X Genomics, Inc. Methods and systems for processing polynucleotides
EP4029939B1 (fr) 2017-01-30 2023-06-28 10X Genomics, Inc. Procédés et systèmes de codage à barres de cellules individuelles sur la base de gouttelettes
GB201703233D0 (en) * 2017-02-28 2017-04-12 Ge Healthcare Bio Sciences Ab A modular bio-processing unit and a bio-processing system employing plural units
CN116064732A (zh) 2017-05-26 2023-05-05 10X基因组学有限公司 转座酶可接近性染色质的单细胞分析
US10400235B2 (en) 2017-05-26 2019-09-03 10X Genomics, Inc. Single cell analysis of transposase accessible chromatin
SG11202000871WA (en) 2017-08-02 2020-02-27 Purigen Biosystems Inc Systems, devices, and methods for isotachophoresis
SG11201913654QA (en) 2017-11-15 2020-01-30 10X Genomics Inc Functionalized gel beads
US10829815B2 (en) 2017-11-17 2020-11-10 10X Genomics, Inc. Methods and systems for associating physical and genetic properties of biological particles
SG11202009889VA (en) 2018-04-06 2020-11-27 10X Genomics Inc Systems and methods for quality control in single cell processing
WO2020175458A1 (fr) * 2019-02-27 2020-09-03 京セラ株式会社 Dispositif de séparation et de mesure de particules et appareil de séparation et de mesure de particules
WO2020189572A1 (fr) * 2019-03-20 2020-09-24 京セラ株式会社 Dispositif de mesure de particules, dispositif de séparation et de mesure de particules et appareil de séparation et de mesure de particules
JP6761153B1 (ja) * 2019-03-20 2020-09-23 京セラ株式会社 粒子計測デバイスならびに粒子分離計測デバイスおよび粒子分離計測装置
CN111085281B (zh) * 2020-01-08 2021-05-14 西安交通大学 一种声表面波调控的高通量微液滴生成装置及方法
CN113063779A (zh) * 2021-03-15 2021-07-02 埃妥生物科技(杭州)有限公司 一种取样器以及样本与试剂的混合装置
WO2023196418A1 (fr) * 2022-04-06 2023-10-12 AtlasXomics Inc. Puce microfluidique

Family Cites Families (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK429682A (da) 1982-09-28 1984-03-29 Inflow Aps Integrerede mikroroersystemer til kontinuerlig gennemstroemningsanalyse
US4946795A (en) * 1987-08-27 1990-08-07 Biotrack, Inc. Apparatus and method for dilution and mixing of liquid samples
JPS6487187A (en) * 1987-09-26 1989-03-31 Kokusan Kogyo Kk Continuous cutter for flexible blank elongated by tensile force
US5070606A (en) * 1988-07-25 1991-12-10 Minnesota Mining And Manufacturing Company Method for producing a sheet member containing at least one enclosed channel
US6176962B1 (en) 1990-02-28 2001-01-23 Aclara Biosciences, Inc. Methods for fabricating enclosed microchannel structures
US5858188A (en) * 1990-02-28 1999-01-12 Aclara Biosciences, Inc. Acrylic microchannels and their use in electrophoretic applications
GB2244135B (en) * 1990-05-04 1994-07-13 Gen Electric Co Plc Sensor devices
SE470347B (sv) * 1990-05-10 1994-01-31 Pharmacia Lkb Biotech Mikrostruktur för vätskeflödessystem och förfarande för tillverkning av ett sådant system
SE9100392D0 (sv) * 1991-02-08 1991-02-08 Pharmacia Biosensor Ab A method of producing a sealing means in a microfluidic structure and a microfluidic structure comprising such sealing means
US5698299A (en) * 1991-02-28 1997-12-16 Dyconex Patente Ag Thin laminated microstructure with precisely aligned openings
US5230866A (en) * 1991-03-01 1993-07-27 Biotrack, Inc. Capillary stop-flow junction having improved stability against accidental fluid flow
US5262127A (en) * 1992-02-12 1993-11-16 The Regents Of The University Of Michigan Solid state chemical micro-reservoirs
US5222808A (en) * 1992-04-10 1993-06-29 Biotrack, Inc. Capillary mixing device
US5545367A (en) * 1992-04-15 1996-08-13 Soane Technologies, Inc. Rapid prototype three dimensional stereolithography
US5726026A (en) 1992-05-01 1998-03-10 Trustees Of The University Of Pennsylvania Mesoscale sample preparation device and systems for determination and processing of analytes
US5639423A (en) * 1992-08-31 1997-06-17 The Regents Of The University Of Calfornia Microfabricated reactor
US5534328A (en) * 1993-12-02 1996-07-09 E. I. Du Pont De Nemours And Company Integrated chemical processing apparatus and processes for the preparation thereof
JP3512186B2 (ja) * 1993-03-19 2004-03-29 イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー 化学処理及び製造のための一体構造及び方法、並びにその使用方法及び製造方法
US5595712A (en) * 1994-07-25 1997-01-21 E. I. Du Pont De Nemours And Company Chemical mixing and reaction apparatus
US5658413A (en) * 1994-10-19 1997-08-19 Hewlett-Packard Company Miniaturized planar columns in novel support media for liquid phase analysis
US5640995A (en) * 1995-03-14 1997-06-24 Baxter International Inc. Electrofluidic standard module and custom circuit board assembly
DE19511603A1 (de) * 1995-03-30 1996-10-02 Norbert Dr Ing Schwesinger Vorrichtung zum Mischen kleiner Flüssigkeitsmengen
WO1997000442A1 (fr) 1995-06-16 1997-01-03 The University Of Washington Procede et dispositif miniaturise d'extraction differentielle
TW293783B (fr) 1995-06-16 1996-12-21 Ciba Geigy Ag
US5856174A (en) * 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device
US5872010A (en) * 1995-07-21 1999-02-16 Northeastern University Microscale fluid handling system
US5849208A (en) * 1995-09-07 1998-12-15 Microfab Technoologies, Inc. Making apparatus for conducting biochemical analyses
US6130098A (en) 1995-09-15 2000-10-10 The Regents Of The University Of Michigan Moving microdroplets
US5658515A (en) * 1995-09-25 1997-08-19 Lee; Abraham P. Polymer micromold and fabrication process
DE19536856C2 (de) 1995-10-03 1997-08-21 Danfoss As Mikromischer und Mischverfahren
DE19541266A1 (de) * 1995-11-06 1997-05-07 Bayer Ag Verfahren und Vorrichtung zur Durchführung chemischer Reaktionen mittels eines Mikrostruktur-Lamellenmischers
US5971158A (en) 1996-06-14 1999-10-26 University Of Washington Absorption-enhanced differential extraction device
EP0909385B1 (fr) * 1996-06-28 2008-09-10 Caliper Life Sciences, Inc. Procédé de transport d'échantillons de fluides par un canal microfluidique
WO1998033585A1 (fr) * 1997-02-05 1998-08-06 California Institute Of Technology Melangeurs de type microfluidique a intervalle d'action infra-milliseconde
DE19708472C2 (de) * 1997-02-20 1999-02-18 Atotech Deutschland Gmbh Herstellverfahren für chemische Mikroreaktoren
SK118099A3 (en) * 1997-02-28 2000-05-16 Burstein Lab Inc Laboratory in a disk
US5904824A (en) * 1997-03-07 1999-05-18 Beckman Instruments, Inc. Microfluidic electrophoresis device
US6235471B1 (en) * 1997-04-04 2001-05-22 Caliper Technologies Corp. Closed-loop biochemical analyzers
US5932315A (en) * 1997-04-30 1999-08-03 Hewlett-Packard Company Microfluidic structure assembly with mating microfeatures
US5869004A (en) 1997-06-09 1999-02-09 Caliper Technologies Corp. Methods and apparatus for in situ concentration and/or dilution of materials in microfluidic systems
US5882465A (en) * 1997-06-18 1999-03-16 Caliper Technologies Corp. Method of manufacturing microfluidic devices
US5771810A (en) * 1997-06-25 1998-06-30 Eastman Kodak Company Continuous tone microfluidic display and printing
US5932799A (en) * 1997-07-21 1999-08-03 Ysi Incorporated Microfluidic analyzer module
US6007775A (en) * 1997-09-26 1999-12-28 University Of Washington Multiple analyte diffusion based chemical sensor
US6136272A (en) 1997-09-26 2000-10-24 University Of Washington Device for rapidly joining and splitting fluid layers
US5842787A (en) * 1997-10-09 1998-12-01 Caliper Technologies Corporation Microfluidic systems incorporating varied channel dimensions
US5945203A (en) * 1997-10-14 1999-08-31 Zms Llc Stratified composite dielectric and method of fabrication
JP2001520377A (ja) 1997-10-15 2001-10-30 アクレイラ バイオサイエンシズ，インコーポレイティド 積層状マイクロ構造式装置および積層状マイクロ構造式装置製造方法
US6074725A (en) * 1997-12-10 2000-06-13 Caliper Technologies Corp. Fabrication of microfluidic circuits by printing techniques
US6050719A (en) 1998-01-30 2000-04-18 Affymetrix, Inc. Rotational mixing method using a cartridge having a narrow interior
AU3771599A (en) * 1998-05-18 1999-12-06 University Of Washington Liquid analysis cartridge
US6494614B1 (en) * 1998-07-27 2002-12-17 Battelle Memorial Institute Laminated microchannel devices, mixing units and method of making same
US6482306B1 (en) * 1998-09-22 2002-11-19 University Of Washington Meso- and microfluidic continuous flow and stopped flow electroösmotic mixer
US6572830B1 (en) 1998-10-09 2003-06-03 Motorola, Inc. Integrated multilayered microfludic devices and methods for making the same
KR20010089295A (ko) 1998-10-13 2001-09-29 마이클 알. 맥닐리 수동 유체 동역학에 의한 유체회로 및 유체회로내에서의방법
US6193471B1 (en) * 1999-06-30 2001-02-27 Perseptive Biosystems, Inc. Pneumatic control of formation and transport of small volume liquid samples
AU7808800A (en) 1999-10-20 2001-04-30 University Of Sheffield, The Fluidic mixer
US6537506B1 (en) * 2000-02-03 2003-03-25 Cellular Process Chemistry, Inc. Miniaturized reaction apparatus
US6409832B2 (en) * 2000-03-31 2002-06-25 Micronics, Inc. Protein crystallization in microfluidic structures
US6561208B1 (en) * 2000-04-14 2003-05-13 Nanostream, Inc. Fluidic impedances in microfluidic system
EP1286913A2 (fr) * 2000-05-24 2003-03-05 Micronics, Inc. Boucle microfluidique servant a produire un gradient de concentration
US20010048637A1 (en) * 2000-05-24 2001-12-06 Weigl Bernhard H. Microfluidic system and method
AU2001280951B2 (en) 2000-08-02 2006-03-02 Caliper Life Sciences, Inc. High throughput separations based analysis systems
EP1320741A4 (fr) * 2000-09-18 2006-09-06 Univ Washington Dispositifs microfluidiques pour manipulation par rotation de l'interface fluidique entre plusieurs ecoulements fluidiques
WO2002022267A2 (fr) * 2000-09-18 2002-03-21 Micronics, Inc. Enduits de surface, pouvant etre modifies par un moyen exterieur, pour dispositifs microfluidiques
WO2002072264A1 (fr) * 2001-03-09 2002-09-19 Biomicro Systems, Inc. Procede et systeme d'interfaçage microfluidique avec des reseaux
US6418968B1 (en) * 2001-04-20 2002-07-16 Nanostream, Inc. Porous microfluidic valves
US6919046B2 (en) * 2001-06-07 2005-07-19 Nanostream, Inc. Microfluidic analytical devices and methods
US20030123322A1 (en) * 2001-12-31 2003-07-03 Industrial Technology Research Institute Microfluidic mixer apparatus and microfluidic reactor apparatus for microfluidic processing

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US20020113009A1 (en) 2002-08-22
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