AU2001280461A1 - Substituted pyrrole compounds and their use as spla2 inhibitors - Google Patents
Substituted pyrrole compounds and their use as spla2 inhibitorsInfo
- Publication number
- AU2001280461A1 AU2001280461A1 AU2001280461A AU8046101A AU2001280461A1 AU 2001280461 A1 AU2001280461 A1 AU 2001280461A1 AU 2001280461 A AU2001280461 A AU 2001280461A AU 8046101 A AU8046101 A AU 8046101A AU 2001280461 A1 AU2001280461 A1 AU 2001280461A1
- Authority
- AU
- Australia
- Prior art keywords
- substituted pyrrole
- pyrrole compounds
- spla2 inhibitors
- spla2
- inhibitors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Physical Education & Sports Medicine (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22339800P | 2000-08-04 | 2000-08-04 | |
US60223398 | 2000-08-04 | ||
US60/223,398 | 2000-08-04 | ||
PCT/US2001/021106 WO2002012249A2 (fr) | 2000-08-04 | 2001-07-20 | Nouveaux inhibiteurs du spla¿2? |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001280461A1 true AU2001280461A1 (en) | 2002-02-18 |
Family
ID=22836318
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001280461A Abandoned AU2001280461A1 (en) | 2000-08-04 | 2001-07-20 | Substituted pyrrole compounds and their use as spla2 inhibitors |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1307461A2 (fr) |
JP (1) | JP2004505982A (fr) |
AU (1) | AU2001280461A1 (fr) |
WO (1) | WO2002012249A2 (fr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7488747B2 (en) | 2003-12-29 | 2009-02-10 | Sepracor Inc. | Pyrrole and pyrazole DAAO inhibitors |
CN101394847B (zh) | 2006-01-06 | 2017-05-24 | 塞普拉柯公司 | 作为单胺重摄取抑制剂的环烷基胺类 |
CN101426372A (zh) | 2006-01-06 | 2009-05-06 | 塞普拉柯公司 | 基于四氢萘酮的单胺再摄取抑制剂 |
CA2648121C (fr) | 2006-03-31 | 2013-08-06 | Sepracor Inc. | Preparation d'amines et amides chiraux |
US7884124B2 (en) | 2006-06-30 | 2011-02-08 | Sepracor Inc. | Fluoro-substituted inhibitors of D-amino acid oxidase |
US7902252B2 (en) | 2007-01-18 | 2011-03-08 | Sepracor, Inc. | Inhibitors of D-amino acid oxidase |
CN101686672A (zh) | 2007-05-31 | 2010-03-31 | 塞普拉柯公司 | 苯基取代的环烷胺作为一元胺再摄取抑制剂 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2537974A1 (fr) * | 1982-12-16 | 1984-06-22 | Adir | Nouveaux derives de thieno (2,3-b) pyrrole, leur procede de preparation et les compositions pharmaceutiques les renfermant |
FR2564467B1 (fr) * | 1984-05-21 | 1987-08-21 | Adir | Nouveaux derives de thieno (2,3-b) pyrrole, leur procede de preparation et les compositions pharmaceutiques les renfermant |
FR2565981B1 (fr) * | 1984-06-15 | 1986-09-19 | Adir | Nouveaux derives de thieno (2,3-b) pyrrole, leur procede de preparation et les compositions pharmaceutiques les renfermant |
DK1950200T3 (da) * | 1994-04-01 | 2012-04-10 | Lilly Co Eli | [[3-(2-AMINO-1,2-DIOXOETHYL)-2-ETHYL-1-(PHENYLMETHYL)-11H-INDOL-4-YL]OXY]EDDIKESYREMETHYLESTER SOM sPLA2-INHIBITOR |
US5919774A (en) * | 1996-12-10 | 1999-07-06 | Eli Lilly And Company | Pyrroles as sPLA2 inhibitors |
EP1011670A4 (fr) * | 1997-08-28 | 2004-10-27 | Lilly Co Eli | Procede servant a traiter la polyarthrite non rhumatoide |
JP2001517707A (ja) * | 1997-09-26 | 2001-10-09 | イーライ・リリー・アンド・カンパニー | 嚢胞性繊維症の処置方法 |
GB9803228D0 (en) * | 1998-02-17 | 1998-04-08 | Zeneca Ltd | Chemical compounds |
KR20010042307A (ko) * | 1998-03-31 | 2001-05-25 | 시오노 요시히코 | 피롤로[1,2-a]피라진 sPLA2 억제제 |
JP4544446B2 (ja) * | 1998-05-21 | 2010-09-15 | 塩野義製薬株式会社 | sPLA2阻害作用を有するピロロ[1,2−b]ピリダジン誘導体 |
DE69934311D1 (de) * | 1998-06-30 | 2007-01-18 | Lilly Co Eli | BICYCLISCHE sPLA 2-INHIBITOREN |
-
2001
- 2001-07-20 JP JP2002518224A patent/JP2004505982A/ja not_active Withdrawn
- 2001-07-20 AU AU2001280461A patent/AU2001280461A1/en not_active Abandoned
- 2001-07-20 WO PCT/US2001/021106 patent/WO2002012249A2/fr active Application Filing
- 2001-07-20 EP EP01958850A patent/EP1307461A2/fr not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
WO2002012249A3 (fr) | 2002-07-18 |
JP2004505982A (ja) | 2004-02-26 |
EP1307461A2 (fr) | 2003-05-07 |
WO2002012249A2 (fr) | 2002-02-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU2001240542A1 (en) | Heterocyclic compounds and their use as parp inhibitors | |
AU2001258771A1 (en) | -secretase inhibitors | |
AU2001274009A1 (en) | Substituted indoles as parp inhibitors | |
AU2001244399A1 (en) | Gamma-secretase inhibitors | |
AU2001237041A1 (en) | Kinase inhibitors | |
AU2001234088A1 (en) | TNF-alpha inhibitors | |
IL145764A0 (en) | Pyrazolobenzodiazepines as cdk2 inhibitors | |
AU2001244355A1 (en) | Heterobiarylsulphonamides and their use as pde 7 inhibitors | |
AU2001280599A1 (en) | Compounds and methods | |
AU2001253418A1 (en) | Compounds and methods | |
HK1049831A1 (zh) | 作為磷酸二酯酶vii抑制劑的吡咯衍生物 | |
AU2001236052A1 (en) | Urease inhibitors | |
AU2001267823A1 (en) | Compounds exhibiting x-type spla2 inhibiting effect | |
AU2002222627A1 (en) | Tak1 inhibitors | |
HK1047276A1 (zh) | 作為pde4抑制劑的四氫噻喃2,3-二氮雜萘酮類衍生物 | |
AU2001243394A1 (en) | Compounds and methods | |
AU2001230605A1 (en) | Apoptosis inhibitor | |
AU2001244562A1 (en) | Neovascularization inhibitors | |
AU2001232245A1 (en) | Tnf- alpha inhibitors | |
AU3235100A (en) | Prothease inhibitors | |
AUPQ872300A0 (en) | Compounds and methods | |
AU2002239263A1 (en) | Tetracyclic carbazole derivates and their use as spla2 inhibitors | |
AU2001280461A1 (en) | Substituted pyrrole compounds and their use as spla2 inhibitors | |
AU2001275794A1 (en) | Pyrrole derivatives | |
AU2001278951A1 (en) | Compounds and methods |