AU2001273300B2 - Apparatus and kits for locking and disinfecting implanted catheters - Google Patents
Apparatus and kits for locking and disinfecting implanted catheters Download PDFInfo
- Publication number
- AU2001273300B2 AU2001273300B2 AU2001273300A AU2001273300A AU2001273300B2 AU 2001273300 B2 AU2001273300 B2 AU 2001273300B2 AU 2001273300 A AU2001273300 A AU 2001273300A AU 2001273300 A AU2001273300 A AU 2001273300A AU 2001273300 B2 AU2001273300 B2 AU 2001273300B2
- Authority
- AU
- Australia
- Prior art keywords
- lower alcohol
- catheter
- volume
- range
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000000249 desinfective effect Effects 0.000 title description 7
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 96
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 51
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims description 48
- 239000003146 anticoagulant agent Substances 0.000 claims description 45
- 229940127219 anticoagulant drug Drugs 0.000 claims description 45
- 239000000203 mixture Substances 0.000 claims description 44
- 150000001875 compounds Chemical class 0.000 claims description 35
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 claims description 32
- 239000004599 antimicrobial Substances 0.000 claims description 31
- 239000000654 additive Substances 0.000 claims description 24
- 230000000996 additive effect Effects 0.000 claims description 21
- 230000000845 anti-microbial effect Effects 0.000 claims description 21
- 238000000034 method Methods 0.000 claims description 21
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 claims description 20
- 239000001509 sodium citrate Substances 0.000 claims description 17
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims description 17
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 claims description 16
- 239000002151 riboflavin Substances 0.000 claims description 16
- 229960002477 riboflavin Drugs 0.000 claims description 16
- 235000019192 riboflavin Nutrition 0.000 claims description 16
- 229960004267 taurolidine Drugs 0.000 claims description 16
- AJKIRUJIDFJUKJ-UHFFFAOYSA-N taurolidine Chemical compound C1NS(=O)(=O)CCN1CN1CNS(=O)(=O)CC1 AJKIRUJIDFJUKJ-UHFFFAOYSA-N 0.000 claims description 15
- XEFQLINVKFYRCS-UHFFFAOYSA-N Triclosan Chemical compound OC1=CC(Cl)=CC=C1OC1=CC=C(Cl)C=C1Cl XEFQLINVKFYRCS-UHFFFAOYSA-N 0.000 claims description 10
- 229960003500 triclosan Drugs 0.000 claims description 10
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims description 9
- 229960001484 edetic acid Drugs 0.000 claims description 9
- 210000004204 blood vessel Anatomy 0.000 claims description 8
- 210000001519 tissue Anatomy 0.000 claims description 7
- 229960004106 citric acid Drugs 0.000 claims description 6
- 229960001790 sodium citrate Drugs 0.000 claims description 6
- 210000003200 peritoneal cavity Anatomy 0.000 claims description 5
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 claims 4
- 230000017531 blood circulation Effects 0.000 claims 2
- 238000007920 subcutaneous administration Methods 0.000 claims 2
- RLYQSPYNMCUCAJ-UHFFFAOYSA-N 1-dodecylpyridin-1-ium-4-carboxylic acid;bromide Chemical compound [Br-].CCCCCCCCCCCC[N+]1=CC=C(C(O)=O)C=C1 RLYQSPYNMCUCAJ-UHFFFAOYSA-N 0.000 claims 1
- OMRDZQXXMYCHBU-UHFFFAOYSA-N ethanol;propan-1-ol Chemical compound CCO.CCCO OMRDZQXXMYCHBU-UHFFFAOYSA-N 0.000 claims 1
- 239000000243 solution Substances 0.000 description 39
- 208000015181 infectious disease Diseases 0.000 description 12
- 238000000502 dialysis Methods 0.000 description 11
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 10
- 229960002897 heparin Drugs 0.000 description 10
- 229920000669 heparin Polymers 0.000 description 10
- 238000001990 intravenous administration Methods 0.000 description 10
- 239000008280 blood Substances 0.000 description 9
- 210000004369 blood Anatomy 0.000 description 9
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 8
- 239000011780 sodium chloride Substances 0.000 description 8
- 238000001631 haemodialysis Methods 0.000 description 7
- 230000000322 hemodialysis Effects 0.000 description 7
- 239000000463 material Substances 0.000 description 7
- 208000007536 Thrombosis Diseases 0.000 description 5
- 150000001298 alcohols Chemical class 0.000 description 5
- 230000035602 clotting Effects 0.000 description 5
- 238000011010 flushing procedure Methods 0.000 description 5
- 238000002615 hemofiltration Methods 0.000 description 5
- DOKHEARVIDLSFF-UHFFFAOYSA-N prop-1-en-1-ol Chemical compound CC=CO DOKHEARVIDLSFF-UHFFFAOYSA-N 0.000 description 5
- 239000000126 substance Substances 0.000 description 5
- 238000011282 treatment Methods 0.000 description 5
- 230000015572 biosynthetic process Effects 0.000 description 4
- 238000001802 infusion Methods 0.000 description 4
- 230000002401 inhibitory effect Effects 0.000 description 4
- 210000003462 vein Anatomy 0.000 description 4
- 206010053567 Coagulopathies Diseases 0.000 description 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- 230000015271 coagulation Effects 0.000 description 3
- 238000005345 coagulation Methods 0.000 description 3
- 239000012530 fluid Substances 0.000 description 3
- 239000011148 porous material Substances 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 description 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000035515 penetration Effects 0.000 description 2
- 210000004303 peritoneum Anatomy 0.000 description 2
- 239000012466 permeate Substances 0.000 description 2
- 229910052708 sodium Inorganic materials 0.000 description 2
- 239000011734 sodium Substances 0.000 description 2
- 230000002792 vascular Effects 0.000 description 2
- MVQXBXLDXSQURK-UHFFFAOYSA-N 2-aminoethanesulfonamide Chemical class NCCS(N)(=O)=O MVQXBXLDXSQURK-UHFFFAOYSA-N 0.000 description 1
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 description 1
- 239000005977 Ethylene Substances 0.000 description 1
- 229920000544 Gore-Tex Polymers 0.000 description 1
- VYTBPJNGNGMRFH-UHFFFAOYSA-N acetic acid;azane Chemical compound N.N.CC(O)=O.CC(O)=O.CC(O)=O.CC(O)=O VYTBPJNGNGMRFH-UHFFFAOYSA-N 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000012377 drug delivery Methods 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 238000000968 medical method and process Methods 0.000 description 1
- 238000002483 medication Methods 0.000 description 1
- 210000004379 membrane Anatomy 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 239000004810 polytetrafluoroethylene Substances 0.000 description 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 229920002379 silicone rubber Polymers 0.000 description 1
- 239000004945 silicone rubber Substances 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- -1 taurolin compound Chemical class 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
- 210000005166 vasculature Anatomy 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
- A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
- A61L29/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/42—Anti-thrombotic agents, anticoagulants, anti-platelet agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/45—Mixtures of two or more drugs, e.g. synergistic mixtures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M2025/0019—Cleaning catheters or the like, e.g. for reuse of the device, for avoiding replacement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0043—Catheters; Hollow probes characterised by structural features
- A61M2025/0056—Catheters; Hollow probes characterised by structural features provided with an antibacterial agent, e.g. by coating, residing in the polymer matrix or releasing an agent out of a reservoir
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Pulmonology (AREA)
- Anesthesiology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- External Artificial Organs (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Materials For Medical Uses (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/611,421 US6679870B1 (en) | 1999-07-23 | 2000-07-07 | Methods and kits for locking and disinfecting implanted catheters |
| US09/611,421 | 2000-07-07 | ||
| US09/859,886 | 2001-05-16 | ||
| US09/859,886 US6685694B2 (en) | 1999-07-23 | 2001-05-16 | Methods and kits for locking and disinfecting implanted catheters |
| PCT/US2001/021656 WO2002005188A1 (en) | 2000-07-07 | 2001-07-09 | Apparatus and kits for locking and disinfecting implanted catheters |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2001273300A1 AU2001273300A1 (en) | 2002-04-18 |
| AU2001273300B2 true AU2001273300B2 (en) | 2007-10-25 |
Family
ID=27086509
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001273300A Expired AU2001273300B2 (en) | 2000-07-07 | 2001-07-09 | Apparatus and kits for locking and disinfecting implanted catheters |
| AU7330001A Pending AU7330001A (en) | 2000-07-07 | 2001-07-09 | Apparatus and kits for locking and disinfecting implanted catheters |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU7330001A Pending AU7330001A (en) | 2000-07-07 | 2001-07-09 | Apparatus and kits for locking and disinfecting implanted catheters |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6685694B2 (enExample) |
| EP (1) | EP1312008B1 (enExample) |
| JP (2) | JP2004516041A (enExample) |
| AU (2) | AU2001273300B2 (enExample) |
| CA (1) | CA2414481A1 (enExample) |
| CY (1) | CY1109200T1 (enExample) |
| DE (1) | DE60138391D1 (enExample) |
| WO (1) | WO2002005188A1 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102781324A (zh) * | 2010-03-03 | 2012-11-14 | 爱德华兹生命科学公司 | 抗凝输液源 |
| US10828484B2 (en) | 2015-08-21 | 2020-11-10 | Medline Industries, Inc. | Disinfecting cap |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6423050B1 (en) * | 2000-06-16 | 2002-07-23 | Zbylut J. Twardowski | Method and apparatus for locking of central-vein catheters |
| US7713472B2 (en) * | 2001-01-12 | 2010-05-11 | Board Of Regents, The University Of Texas System | Antiseptic derivatives with broad spectrum antimicrobial activity for the impregnation of surfaces |
| US20040092890A1 (en) * | 2001-05-10 | 2004-05-13 | Ash Stephen R. | Catheter lock solution including a photo-oxidant |
| US20050215978A1 (en) * | 2001-05-25 | 2005-09-29 | Ash Stephen R | Method of enhancing catheter patency using a citrate salt catheter lock solution |
| AU2002353061B2 (en) * | 2001-12-05 | 2008-07-10 | Aseptica, Inc. | Anti-microbial systems and methods |
| US8541472B2 (en) | 2001-12-05 | 2013-09-24 | Aseptica, Inc. | Antiseptic compositions, methods and systems |
| EP1442753B1 (en) * | 2003-02-03 | 2007-02-21 | Polaschegg, Hans-Dietrich, Dr.techn. | Composition for the prevention of indwelling device related infection |
| US7435237B2 (en) * | 2003-06-02 | 2008-10-14 | Boston Scientific Scimed, Inc. | Mixing syringes with breakable septums |
| PL1644024T3 (pl) | 2003-06-06 | 2020-03-31 | Board Of Regents, The University Of Texas System | Przeciwdrobnoustrojowe roztwory do płukania |
| US7652040B2 (en) * | 2003-06-19 | 2010-01-26 | Janssen Pharmaceutica N.V. | Aminosulfonyl substituted 4-(aminomethyl)-piperidine benzamides as 5HT4-antagonists |
| JP2007522835A (ja) * | 2004-01-20 | 2007-08-16 | ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム | 医療装置に消毒組成物をコーティングする、および含浸させる方法 |
| JP2007537200A (ja) * | 2004-05-14 | 2007-12-20 | ハンス−ディートリヒ・ポラシェグ | タウロリジン製剤及び投与:細菌マイクロフィルム形成に対する治療処置及び抗菌保護 |
| US7696182B2 (en) * | 2004-11-02 | 2010-04-13 | Nd Partners, Llc | Antimicrobial locking solutions comprising taurinamide derivatives and biologically acceptable salts and acids, with the addition of small concentrations of heparin |
| US20060095021A1 (en) * | 2004-11-02 | 2006-05-04 | Casas-Bejar Jesus W | Introduction of agent with medical device |
| US7749529B2 (en) * | 2005-02-08 | 2010-07-06 | Ash Access Technology, Inc. | Catheter lock solution comprising citrate and a paraben |
| US8496631B2 (en) * | 2005-07-05 | 2013-07-30 | David C. Brown | Apparatus and method for increasing flow resistance around a probe |
| US20070154621A1 (en) | 2005-11-18 | 2007-07-05 | Issam Raad | Methods for coating surfaces with antimicrobial agents |
| ES2862464T3 (es) * | 2006-02-28 | 2021-10-07 | Becton Dickinson Co | Composiciones antimicrobianas y métodos para bloquear catéteres |
| US11229746B2 (en) | 2006-06-22 | 2022-01-25 | Excelsior Medical Corporation | Antiseptic cap |
| US9700710B2 (en) | 2006-06-22 | 2017-07-11 | Excelsior Medical Corporation | Antiseptic cap equipped syringe |
| US8167847B2 (en) | 2006-06-22 | 2012-05-01 | Excelsior Medical Corporation | Antiseptic cap and antiseptic cap equipped plunger and syringe barrel assembly |
| US9259535B2 (en) | 2006-06-22 | 2016-02-16 | Excelsior Medical Corporation | Antiseptic cap equipped syringe |
| KR100791477B1 (ko) * | 2006-08-08 | 2008-01-03 | 삼성전자주식회사 | 상변화 메모리 유닛, 이의 제조 방법, 이를 포함하는상변화 메모리 장치 및 그 제조 방법 |
| WO2008060380A2 (en) * | 2006-10-18 | 2008-05-22 | Arrow International, Inc. | Anti-infective alcohol catheter solution with chlorhexidine treated catheter |
| DE102006062111A1 (de) | 2006-12-23 | 2008-06-26 | Farco-Pharma Gmbh | Zusammensetzung, insbesondere für das Blockieren von Kathetern |
| DE102007009506B3 (de) * | 2007-02-25 | 2008-04-30 | Kleophas, Werner, Dr. | Doppellumenkatheteranordnung |
| US8389583B2 (en) | 2008-05-23 | 2013-03-05 | Zurex Pharma, Inc. | Antimicrobial compositions and methods of use |
| US9078992B2 (en) | 2008-10-27 | 2015-07-14 | Pursuit Vascular, Inc. | Medical device for applying antimicrobial to proximal end of catheter |
| US8864742B2 (en) * | 2008-11-12 | 2014-10-21 | Cary Pharmaceuticals Inc. | Catheter locking composition |
| WO2011019710A2 (en) * | 2009-08-10 | 2011-02-17 | Proviflo, Llc | Catheter lock solutions utilizing tocopheraol and mid-chain fatty acids |
| US10016587B2 (en) | 2011-05-20 | 2018-07-10 | Excelsior Medical Corporation | Caps for needleless connectors |
| US9867975B2 (en) | 2011-05-23 | 2018-01-16 | Excelsior Medical Corporation | Antiseptic line cap |
| US10166381B2 (en) | 2011-05-23 | 2019-01-01 | Excelsior Medical Corporation | Antiseptic cap |
| CN106902405B (zh) | 2011-07-12 | 2020-12-11 | Icu医学有限公司 | 用于将抗微生物剂递送到经皮导管中的装置 |
| WO2013032464A1 (en) * | 2011-08-31 | 2013-03-07 | Organic Medical Ventures, L.L.C. | Transdermal venous access locking solutions |
| WO2014004498A1 (en) * | 2012-06-25 | 2014-01-03 | Medical Components, Inc. | Citrate anticoagulant underloaded syringe for catheter locking |
| US10300176B2 (en) | 2013-11-25 | 2019-05-28 | Medline Industries, Inc. | Catheter lock solution formulations |
| JP6546988B2 (ja) | 2014-05-02 | 2019-07-17 | エクセルシオール・メディカル・コーポレイションExcelsior Medical Corporation | 防腐キャップのためのストリップパッケージ |
| WO2016182822A1 (en) | 2015-05-08 | 2016-11-17 | Icu Medical, Inc. | Medical connectors configured to receive emitters of therapeutic agents |
| US10456570B2 (en) | 2015-06-11 | 2019-10-29 | Proviflo, Llc | Graft-port hemodialysis systems, devices, and methods |
| CA3013914C (en) * | 2016-02-12 | 2024-02-06 | Medical Components, Inc. | Catheter locking solution and catheter locking therapy |
| PT3525865T (pt) | 2016-10-14 | 2022-11-17 | Icu Medical Inc | Tampas de higienização para conectores médicos |
| WO2018204206A2 (en) | 2017-05-01 | 2018-11-08 | Icu Medical, Inc. | Medical fluid connectors and methods for providing additives in medical fluid lines |
| US11045589B2 (en) | 2017-09-22 | 2021-06-29 | Becton, Dickinson And Company | 4% trisodium citrate solution for use as a catheter lock solution |
| US11541221B2 (en) | 2018-11-07 | 2023-01-03 | Icu Medical, Inc. | Tubing set with antimicrobial properties |
| US11400195B2 (en) | 2018-11-07 | 2022-08-02 | Icu Medical, Inc. | Peritoneal dialysis transfer set with antimicrobial properties |
| US11534595B2 (en) | 2018-11-07 | 2022-12-27 | Icu Medical, Inc. | Device for delivering an antimicrobial composition into an infusion device |
| US11541220B2 (en) | 2018-11-07 | 2023-01-03 | Icu Medical, Inc. | Needleless connector with antimicrobial properties |
| US11517732B2 (en) | 2018-11-07 | 2022-12-06 | Icu Medical, Inc. | Syringe with antimicrobial properties |
| CA3118905A1 (en) | 2018-11-21 | 2020-05-28 | Icu Medical, Inc. | Antimicrobial device comprising a cap with ring and insert |
| CA3204371A1 (en) | 2020-12-07 | 2022-06-16 | Icu Medical, Inc. | Peritoneal dialysis caps, systems and methods |
| DE102021202647A1 (de) * | 2021-03-18 | 2022-09-22 | B. Braun Melsungen Aktiengesellschaft | Medizinprodukt und Verfahren zur Herstellung eines solchen Medizinprodukts |
| US11738120B1 (en) * | 2022-04-14 | 2023-08-29 | Cormedix Inc. | Synthesis of taurolidine, purity profiles and polymorphs |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5053021A (en) * | 1989-05-05 | 1991-10-01 | Feibus Miriam H | Surgical drain |
| US5587358A (en) * | 1994-05-09 | 1996-12-24 | Asahi Kasei Kogyo Kabushiki Kaisha | Potentiators of antimicrobial activity |
Family Cites Families (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4107305A (en) | 1975-08-04 | 1978-08-15 | Ed. Geistlich Sohne A.G. Fur Chemische Industrie | Treatment of endotoxaemia |
| US4069185A (en) * | 1976-04-22 | 1978-01-17 | Corning Glass Works | Anticoagulant coating composition |
| US4445889A (en) | 1977-06-09 | 1984-05-01 | Alza Corporation | Method for delivering an agent with biocidal activity in a body fluid receiving container |
| CA1190855A (en) | 1980-09-03 | 1985-07-23 | Rolf W. Pfirrmann | Treatment of osteitis |
| GB8328111D0 (en) | 1983-10-20 | 1983-11-23 | Geistlich Soehne Ag | Chemical compounds |
| DE3506288A1 (de) | 1984-09-06 | 1986-03-13 | Johannes 7900 Ulm Reinmüller | Vorrichtung zum einlegen in wunden und wundhoehlen |
| DE3513938A1 (de) | 1985-04-18 | 1986-10-23 | Merck Patent Gmbh, 6100 Darmstadt | Cytostatikahaltiges pharmakadepot |
| DE3533612A1 (de) | 1985-09-20 | 1987-04-02 | Johannes Reinmueller | Neuartige verwendung von taurolin |
| DE3542972A1 (de) | 1985-12-05 | 1987-06-11 | Merck Patent Gmbh | Pharmakadepot |
| US5210083A (en) | 1986-07-17 | 1993-05-11 | Ed. Geistlich Sohne A.G. Fur Chemische Industrie | Pharmaceutical compositions |
| US4929242A (en) | 1986-11-26 | 1990-05-29 | Baxter International Inc. | Solution and method for maintaining patency of a catheter |
| US4954239A (en) * | 1988-04-15 | 1990-09-04 | Mueller Louis H | Prefilled catheter tip syringe kit |
| US5093117A (en) | 1989-01-24 | 1992-03-03 | Baxter International Inc. | Compositions and method for the treatment or prophylaxis of sepsis or septic shock |
| US5174990A (en) * | 1990-02-07 | 1992-12-29 | 7-L Corporation | Mouthrinse and method of preparation |
| US5263930A (en) | 1990-03-01 | 1993-11-23 | William D. Ensminger | Implantable access devices |
| GB9005856D0 (en) | 1990-03-15 | 1990-05-09 | Geistlich Soehne Ag | Compositions |
| US5142010A (en) * | 1990-05-10 | 1992-08-25 | H. B. Fuller Licensing & Financing Inc. | Polymeric biocidal agents |
| US5358492A (en) * | 1991-05-02 | 1994-10-25 | Feibus Miriam H | Woven surgical drain and method of making |
| US5281205A (en) | 1992-03-11 | 1994-01-25 | Mcpherson William E | Vascular access system and clearing method |
| US5344455A (en) | 1992-10-30 | 1994-09-06 | Medtronic, Inc. | Graft polymer articles having bioactive surfaces |
| US5954239A (en) | 1992-11-10 | 1999-09-21 | Evnx Technologies, Inc. | Aerosol spray dispenser with swinging downtube |
| US5362754A (en) | 1992-11-12 | 1994-11-08 | Univ. Of Tx Md Anderson Cancer Center | M-EDTA pharmaceutical preparations and uses thereof |
| US5688516A (en) * | 1992-11-12 | 1997-11-18 | Board Of Regents, The University Of Texas System | Non-glycopeptide antimicrobial agents in combination with an anticoagulant, an antithrombotic or a chelating agent, and their uses in, for example, the preparation of medical devices |
| DE69427901T2 (de) * | 1993-01-07 | 2002-04-04 | Medical Innovations Corp., Milpitas | Kathetersystem für die gastrostomie |
| WO1994015640A1 (en) | 1993-01-12 | 1994-07-21 | Anthony George Gristina | Methods and compositions for the direct concentrated delivery of passive immunity |
| US5308338A (en) * | 1993-04-22 | 1994-05-03 | Helfrich G Baird | Catheter or the like with medication injector to prevent infection |
| US5807356A (en) | 1994-01-18 | 1998-09-15 | Vasca, Inc. | Catheter with valve |
| US6042569A (en) | 1994-01-18 | 2000-03-28 | Vasca, Inc. | Subcutaneously implanted cannula and methods for vascular access |
| US5562617A (en) | 1994-01-18 | 1996-10-08 | Finch, Jr.; Charles D. | Implantable vascular device |
| HUT74669A (en) | 1994-02-15 | 1997-01-28 | Lepetit Spa | Central venous catheters loaded with antibiotics of the ramoplanin group preventing development of catheter related infections |
| US5788979A (en) | 1994-07-22 | 1998-08-04 | Inflow Dynamics Inc. | Biodegradable coating with inhibitory properties for application to biocompatible materials |
| US5704915A (en) | 1995-02-14 | 1998-01-06 | Therex Limited Partnership | Hemodialysis access device |
| US5624704A (en) * | 1995-04-24 | 1997-04-29 | Baylor College Of Medicine | Antimicrobial impregnated catheters and other medical implants and method for impregnating catheters and other medical implants with an antimicrobial agent |
| US5954691A (en) | 1995-06-07 | 1999-09-21 | Biolink Corporation | Hemodialysis access apparatus |
| US6206851B1 (en) | 1995-06-07 | 2001-03-27 | Biolink Corporation | Hemodialysis access apparatus |
| US5772640A (en) | 1996-01-05 | 1998-06-30 | The Trustees Of Columbia University Of The City Of New York | Triclosan-containing medical devices |
| DE69632996T2 (de) | 1995-12-26 | 2005-07-21 | Toyo Boseki K.K. | In organischen Lösungsmitteln lösliche Mucopolysaccharide, antibakterielles antithrombogenes Mittel und medizinisches Material |
| US6063061A (en) * | 1996-08-27 | 2000-05-16 | Fusion Medical Technologies, Inc. | Fragmented polymeric compositions and methods for their use |
| US5931829A (en) | 1997-01-21 | 1999-08-03 | Vasca, Inc. | Methods and systems for establishing vascular access |
| US6193684B1 (en) | 1997-01-21 | 2001-02-27 | Vasca, Inc. | Device for percutaneous peritoneal dialysis |
| US6007516A (en) | 1997-01-21 | 1999-12-28 | Vasca, Inc. | Valve port and method for vascular access |
| US5989239A (en) | 1997-01-21 | 1999-11-23 | Vasca, Inc. | Method and apparatus for percutaneously accessing an implanted port |
| EP0996481A1 (en) | 1997-07-18 | 2000-05-03 | Vasca, Inc. | Method and apparatus for percutaneously accessing an implanted port |
| US5997524A (en) | 1997-07-18 | 1999-12-07 | Vasca, Inc. | Catheter assembly for percutaneous access to subcutaneous port |
| US6146373A (en) * | 1997-10-17 | 2000-11-14 | Micro Therapeutics, Inc. | Catheter system and method for injection of a liquid embolic composition and a solidification agent |
| US6159232A (en) * | 1997-12-16 | 2000-12-12 | Closys Corporation | Clotting cascade initiating apparatus and methods of use and methods of closing wounds |
| US6299610B1 (en) * | 1998-01-07 | 2001-10-09 | Vasca, Inc. | Methods and apparatus for disinfecting subcutaneously implanted devices |
| US6299609B1 (en) | 1998-01-07 | 2001-10-09 | Vasca, Inc. | Methods and apparatus for inhibiting infection of subcutaneously implanted devices |
| US6248343B1 (en) * | 1998-01-20 | 2001-06-19 | Ethicon, Inc. | Therapeutic antimicrobial compositions |
| US6059766A (en) | 1998-02-27 | 2000-05-09 | Micro Therapeutics, Inc. | Gynecologic embolotherapy methods |
| US6361524B1 (en) * | 1998-04-14 | 2002-03-26 | Becton, Dickinson And Company | Syringe assembly |
| US6166007A (en) | 1998-07-02 | 2000-12-26 | Sodemann; Klaus | Antimicrobial locks comprising taurinamide derivatives and carboxylic acids and/or salts thereof |
| EP1107807B1 (en) * | 1998-08-25 | 2006-10-11 | Ash Access Technology, Inc. | Use of citrate in a catheter lock solution |
| US6132415A (en) | 1999-02-09 | 2000-10-17 | Vasca, Inc. | Systems and methods for removing retained fluids and infusing therapeutic fluids |
| US6350251B1 (en) * | 2000-01-18 | 2002-02-26 | Biolink Corporation | Biocidal locks |
-
2001
- 2001-05-16 US US09/859,886 patent/US6685694B2/en not_active Expired - Lifetime
- 2001-07-09 JP JP2002508720A patent/JP2004516041A/ja active Pending
- 2001-07-09 AU AU2001273300A patent/AU2001273300B2/en not_active Expired
- 2001-07-09 WO PCT/US2001/021656 patent/WO2002005188A1/en not_active Ceased
- 2001-07-09 DE DE60138391T patent/DE60138391D1/de not_active Expired - Lifetime
- 2001-07-09 EP EP01952563A patent/EP1312008B1/en not_active Revoked
- 2001-07-09 CA CA002414481A patent/CA2414481A1/en not_active Abandoned
- 2001-07-09 AU AU7330001A patent/AU7330001A/xx active Pending
-
2009
- 2009-07-07 CY CY20091100713T patent/CY1109200T1/el unknown
-
2013
- 2013-08-05 JP JP2013162527A patent/JP2013255823A/ja active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5053021A (en) * | 1989-05-05 | 1991-10-01 | Feibus Miriam H | Surgical drain |
| US5587358A (en) * | 1994-05-09 | 1996-12-24 | Asahi Kasei Kogyo Kabushiki Kaisha | Potentiators of antimicrobial activity |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102781324A (zh) * | 2010-03-03 | 2012-11-14 | 爱德华兹生命科学公司 | 抗凝输液源 |
| US10828484B2 (en) | 2015-08-21 | 2020-11-10 | Medline Industries, Inc. | Disinfecting cap |
| US11464962B2 (en) | 2015-08-21 | 2022-10-11 | Medline Industries, Lp | Disinfecting cap |
| US12083309B2 (en) | 2015-08-21 | 2024-09-10 | Medline Industries, Lp | Disinfecting cap |
| US12186522B2 (en) | 2015-08-21 | 2025-01-07 | Medline Industries, Inc. | Disinfecting cap |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1312008A1 (en) | 2003-05-21 |
| CA2414481A1 (en) | 2002-01-17 |
| EP1312008B1 (en) | 2009-04-15 |
| JP2004516041A (ja) | 2004-06-03 |
| US20020010438A1 (en) | 2002-01-24 |
| DE60138391D1 (de) | 2009-05-28 |
| EP1312008A4 (en) | 2004-07-07 |
| WO2002005188A1 (en) | 2002-01-17 |
| CY1109200T1 (el) | 2014-07-02 |
| US6685694B2 (en) | 2004-02-03 |
| AU7330001A (en) | 2002-01-21 |
| JP2013255823A (ja) | 2013-12-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2001273300B2 (en) | Apparatus and kits for locking and disinfecting implanted catheters | |
| US6679870B1 (en) | Methods and kits for locking and disinfecting implanted catheters | |
| US6592564B2 (en) | Methods and kits for locking and disinfecting implanted catheters | |
| AU2001273300A1 (en) | Apparatus and kits for locking and disinfecting implanted catheters | |
| EP2464406B1 (en) | Catheter lock solutions utilizing tocopherol and mid-chain fatty acids | |
| US6482197B2 (en) | Methods and apparatus for inhibiting infection of subcutaneously implanted devices | |
| US6958049B1 (en) | Method of enhancing catheter patency using a citrate salt catheter lock solution | |
| US20130183363A1 (en) | Prevention of indwelling device related infection: composition and methods | |
| CN101442956A (zh) | 包含柠檬酸盐和对羟基苯甲酸酯的封管溶液 | |
| JP2005515838A (ja) | カニューレ用高粘性率抗菌剤 | |
| US20050215978A1 (en) | Method of enhancing catheter patency using a citrate salt catheter lock solution | |
| WO2015077798A1 (en) | Catheter lock solution formulations | |
| WO2001085249B1 (en) | A catheter lock solution including a photo-oxidant | |
| WO2000010385A1 (en) | Method of enhancing catheter patency using a citrate salt catheter lock solution | |
| Devine et al. | The permanent Tenckhoff catheter for chronic peritoneal dialysis | |
| US20100249747A1 (en) | Transdermal venous access locking solution | |
| US6436084B1 (en) | Methods and apparatus for disinfecting subcutaneously implanted devices | |
| CN100574813C (zh) | 用于医疗装置的洛克溶液及其用途 | |
| JP2002500072A (ja) | 皮下移植装置を消毒する方法および機器 | |
| JP7138702B2 (ja) | カテーテルロック溶液としての使用のための4%クエン酸三ナトリウム溶液 | |
| JP2010279713A (ja) | 挿入カテーテルをロックして消毒するための装置およびキット | |
| JP2004503336A (ja) | 液体をカテーテル内へ注入するための装置及び方法 | |
| Donnelly et al. | Surgical management of long-term central venous access in uraemic patients | |
| Buselmeier et al. | A new subcutaneous arteriovenous shunt: applicable in cases where the standard Quinton-Scribner shunt and arteriovenous fistula have failed | |
| JP2010178786A (ja) | 静菌効果を有するカテーテルロック液と該カテーテルロック液の調製方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC1 | Assignment before grant (sect. 113) |
Owner name: EXCEISIOR MEDICAL CORPORATION Free format text: FORMER APPLICANT(S): VASCA, INC |
|
| TH | Corrigenda |
Free format text: IN VOL 21, NO 8, PAGE(S) 827 UNDER THE HEADING ASSIGNMENTS BEFORE GRANT, SECTION 113 - 2001 UNDER THE NAME EXCEISIOR MEDICAL CORPORATION, APPLICATION NO.2001273300, UNDER INID (71), CORRECT THE NAME TO READ EXCELSIOR MEDICAL CORPORATION |
|
| FGA | Letters patent sealed or granted (standard patent) | ||
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |