AU2001266567A1 - A thiazine oxazolidinone - Google Patents

A thiazine oxazolidinone

Info

Publication number
AU2001266567A1
AU2001266567A1 AU2001266567A AU6656701A AU2001266567A1 AU 2001266567 A1 AU2001266567 A1 AU 2001266567A1 AU 2001266567 A AU2001266567 A AU 2001266567A AU 6656701 A AU6656701 A AU 6656701A AU 2001266567 A1 AU2001266567 A1 AU 2001266567A1
Authority
AU
Australia
Prior art keywords
compound
pharmaceutical composition
formula
composition according
aqueous pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001266567A
Other languages
English (en)
Inventor
Michael R. Barbachyn
Gary E. Zurenko
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co LLC
Original Assignee
Pharmacia and Upjohn Co
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia and Upjohn Co, Upjohn Co filed Critical Pharmacia and Upjohn Co
Publication of AU2001266567A1 publication Critical patent/AU2001266567A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AU2001266567A 2000-06-16 2001-06-14 A thiazine oxazolidinone Abandoned AU2001266567A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US21247400P 2000-06-16 2000-06-16
US60212474 2000-06-16
US23659500P 2000-09-29 2000-09-29
US60236595 2000-09-29
US28558701P 2001-04-20 2001-04-20
US60285587 2001-04-20
PCT/US2001/014854 WO2001098297A2 (fr) 2000-06-16 2001-06-14 Thiazine oxazolidinone

Publications (1)

Publication Number Publication Date
AU2001266567A1 true AU2001266567A1 (en) 2002-01-02

Family

ID=27395744

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001266567A Abandoned AU2001266567A1 (en) 2000-06-16 2001-06-14 A thiazine oxazolidinone

Country Status (16)

Country Link
US (1) US6605609B2 (fr)
EP (1) EP1294717B1 (fr)
JP (1) JP2004501150A (fr)
KR (1) KR20030010721A (fr)
CN (1) CN1430618A (fr)
AR (1) AR028706A1 (fr)
AT (1) ATE312098T1 (fr)
AU (1) AU2001266567A1 (fr)
BR (1) BR0111520A (fr)
CA (1) CA2410358A1 (fr)
DE (1) DE60115644T2 (fr)
ES (1) ES2253392T3 (fr)
MX (1) MXPA02012494A (fr)
PE (1) PE20020044A1 (fr)
TW (1) TW583184B (fr)
WO (1) WO2001098297A2 (fr)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6544555B2 (en) 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
PE20020300A1 (es) * 2000-08-22 2002-05-10 Pharmacia Corp Composicion de solucion de un farmaco antibiotico a base de oxazolidinona con mejoramiento de la carga de farmaco
US6696426B2 (en) * 2000-08-22 2004-02-24 Pharmacia Corporation Preservative free ophthalmic oxazolidinone antibiotic drug delivery systems
US20020068078A1 (en) 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
WO2002085865A1 (fr) * 2001-04-20 2002-10-31 Pharmacia & Upjohn Company Procede de preparation d'oxazolidinones
NZ528996A (en) 2001-04-20 2006-01-27 Upjohn Co Process to prepare oxazolidinones
WO2003006441A1 (fr) * 2001-07-10 2003-01-23 Pharmacia & Upjohn Company Cristaux a base de thiazine oxazolidinones
WO2003093247A2 (fr) * 2002-04-30 2003-11-13 Orchid Chemicals & Pharmaceuticals Ltd Nouveaux agents antibacteriens
EP1515768B1 (fr) * 2002-05-07 2013-11-06 The State University of New York at Stony Brook Dispositifs pour therapie endobronchique ciblée
TW200403240A (en) 2002-06-28 2004-03-01 Upjohn Co Difluorothioacetamides of oxazolidinones as antibacterial agents
US6875784B2 (en) * 2002-10-09 2005-04-05 Pharmacia & Upjohn Company Antimibicrobial [3.1.0.] bicyclic oxazolidinone derivatives
JP2006528190A (ja) 2003-07-21 2006-12-14 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
JP2006528185A (ja) 2003-07-21 2006-12-14 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
US8313776B2 (en) 2003-07-21 2012-11-20 Shionogi Inc. Antibiotic product, use and formulation thereof
CA2535177A1 (fr) 2003-08-11 2005-02-24 Advancis Pharmaceutical Corporation Pastille robuste
CA2535398C (fr) 2003-08-12 2013-11-12 Advancis Pharmaceuticals Corporation Antibiotique, utilisation et formulation associees
AU2004270170B2 (en) * 2003-08-29 2011-01-27 Shionogi, Inc. Antibiotic product, use and formulation thereof
WO2005027877A1 (fr) 2003-09-15 2005-03-31 Advancis Pharmaceutical Corporation Antibiotique, son utilisation et sa formulation
TWI357901B (en) * 2004-03-12 2012-02-11 Lundbeck & Co As H Substituted morpholine and thiomorpholine derivati
WO2005113520A1 (fr) * 2004-05-20 2005-12-01 Pharmacia & Upjohn Company Llc 2,3,5-trifluorphenyl oxazolidinones substitues a utiliser en tant qu'agents antibacteriens
JP2008505124A (ja) 2004-07-02 2008-02-21 アドバンシス ファーマスーティカル コーポレイション パルス送達用錠剤
US7838532B2 (en) * 2005-05-18 2010-11-23 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
US8524735B2 (en) 2005-05-18 2013-09-03 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
JP5368092B2 (ja) * 2005-08-11 2013-12-18 ターガンタ セラピュティクス，インコーポレイティド ホスホン化リファマイシン類および骨と関節感染の予防と治療のためのその投与法
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
US8778924B2 (en) 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
US8299052B2 (en) * 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
EP2018864A1 (fr) 2007-07-23 2009-01-28 Biomet Deutschland GmbH Composition pharmaceutique, substrat comprenant une composition pharmaceutique et utilisation d'une composition pharmaceutique
HUE038428T2 (hu) 2008-10-07 2018-10-29 Horizon Orphan Llc Aeroszol fluorokinolon készítmények javított farmakokinetika érdekében
WO2010042549A1 (fr) 2008-10-07 2010-04-15 Mpex Pharmaceuticals, Inc. Inhalation de lévofloxacine pour réduire une inflammation des poumons
PT2473170T (pt) 2009-09-04 2019-08-23 Horizon Orphan Llc Utilização de levofloxacina em aerossol para tratamento de fibrose cística
US10010758B2 (en) * 2015-07-20 2018-07-03 Kinetic Furniture Of Vermont, Llc Exercise chair
CN106770222A (zh) * 2016-11-23 2017-05-31 百奥森（江苏）食品安全科技有限公司 一种食品中甲硝唑的检测试剂盒
CN108239098B (zh) * 2016-12-26 2021-01-12 中国医学科学院药物研究所 含四氢吡啶的苯并噁嗪噁唑烷酮类化合物及其制备方法和用途
CA3059880A1 (fr) * 2017-04-14 2018-10-18 Nal Pharmaceutical Group Limited Seringue pre-remplie contenant de la moxifloxacine
WO2021184339A1 (fr) * 2020-03-20 2021-09-23 Merck Sharp & Dohme Corp. Composé d'oxazolidinone et procédés d'utilisation de celui-ci comme agent antibactérien
CN111870594B (zh) * 2020-08-27 2022-03-22 首都医科大学附属北京胸科医院 苯乙肼在制备抗偶发分枝杆菌感染的药物中的应用
WO2024035618A1 (fr) * 2022-08-10 2024-02-15 Merck Sharp & Dohme Llc Procédés de préparation de composés d'oxazolidinone

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5688792A (en) * 1994-08-16 1997-11-18 Pharmacia & Upjohn Company Substituted oxazine and thiazine oxazolidinone antimicrobials
RU2175324C2 (ru) 1995-09-01 2001-10-27 Фармация Энд Апджон Компани Фенилоксазолидиноны, имеющие с-с-связь с 4-8-членными гетероциклическими кольцами
GB9702213D0 (en) 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
CA2285446A1 (fr) * 1997-03-13 1998-09-17 Smithkline Beecham P.L.C. Derives de pyrrolidine et thiazole aux proprietes inhibant la beta-lactamase metallique
WO2001034128A2 (fr) 1999-11-08 2001-05-17 Pharmacia & Upjohn Company Melange de linezolid et d'autres agents antibacteriens

Also Published As

Publication number Publication date
CN1430618A (zh) 2003-07-16
BR0111520A (pt) 2003-03-18
ATE312098T1 (de) 2005-12-15
EP1294717B1 (fr) 2005-12-07
DE60115644D1 (en) 2006-01-12
WO2001098297A3 (fr) 2002-06-13
AR028706A1 (es) 2003-05-21
TW583184B (en) 2004-04-11
ES2253392T3 (es) 2006-06-01
CA2410358A1 (fr) 2001-12-27
EP1294717A2 (fr) 2003-03-26
US6605609B2 (en) 2003-08-12
WO2001098297A2 (fr) 2001-12-27
JP2004501150A (ja) 2004-01-15
DE60115644T2 (de) 2006-07-06
PE20020044A1 (es) 2002-01-30
KR20030010721A (ko) 2003-02-05
US20020156072A1 (en) 2002-10-24
MXPA02012494A (es) 2003-04-25

Similar Documents

Publication Publication Date Title
EP1294717B1 (fr) Thiazine oxazolidinone
EP1432705B1 (fr) Antibiotiques a double action
EP1263742B1 (fr) Thioamides d'oxazolidinone a substituants amides de piperazine
EP1036074B1 (fr) S-oxyde tetrahydrothiopyranne
US6927229B2 (en) Difluorothioacetamides of oxazolidinones as antibacterial agents
US20030216330A1 (en) Parenteral, intravenous, and oral administration of oxazolidinones for treating diabetic foot infections
WO2005113520A1 (fr) 2,3,5-trifluorphenyl oxazolidinones substitues a utiliser en tant qu'agents antibacteriens
JP2004501965A (ja) 細菌感染を治療するための組成物および方法
US6297242B1 (en) N-substituted amidine and guanidine oxazolidinone antibacterials and methods of use thereof
ZA200209575B (en) A thiazine oxazolidinone.
US20040072842A1 (en) Difluorothioacetamides of oxazolidinones with a glycoloylpiperazine substituent
WO2006018682A2 (fr) Derives d'oxazolidinone comme antimicrobiens

Legal Events

Date Code Title Description
MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application