AU2001258667A1 - A method for designing and screening random libraries of compounds - Google Patents

A method for designing and screening random libraries of compounds

Info

Publication number
AU2001258667A1
AU2001258667A1 AU2001258667A AU5866701A AU2001258667A1 AU 2001258667 A1 AU2001258667 A1 AU 2001258667A1 AU 2001258667 A AU2001258667 A AU 2001258667A AU 5866701 A AU5866701 A AU 5866701A AU 2001258667 A1 AU2001258667 A1 AU 2001258667A1
Authority
AU
Australia
Prior art keywords
designing
compounds
random libraries
screening random
screening
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001258667A
Inventor
Valery Alakhov
Rosemonde Mandeville
Mikhail Popkov
Oleg Romar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Supratek Pharma Inc
Biophage Inc
Original Assignee
Supratek Pharma Inc
Biophage Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Supratek Pharma Inc, Biophage Inc filed Critical Supratek Pharma Inc
Publication of AU2001258667A1 publication Critical patent/AU2001258667A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1086Preparation or screening of expression libraries, e.g. reporter assays
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1037Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/02Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Virology (AREA)
  • Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU2001258667A 2000-05-12 2001-05-11 A method for designing and screening random libraries of compounds Abandoned AU2001258667A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US57047700A 2000-05-12 2000-05-12
US09/570,477 2000-05-12
PCT/IB2001/000810 WO2001086293A2 (en) 2000-05-12 2001-05-11 A method for designing and screening random libraries of compounds

Publications (1)

Publication Number Publication Date
AU2001258667A1 true AU2001258667A1 (en) 2001-11-20

Family

ID=24279792

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001258667A Abandoned AU2001258667A1 (en) 2000-05-12 2001-05-11 A method for designing and screening random libraries of compounds

Country Status (5)

Country Link
EP (1) EP1309869A1 (en)
JP (1) JP2003532431A (en)
AU (1) AU2001258667A1 (en)
CA (1) CA2408652A1 (en)
WO (1) WO2001086293A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030224480A1 (en) * 2001-12-27 2003-12-04 Fujitsu Limited Method of designing multifunctional base sequence
JP4953046B2 (en) * 2005-07-29 2012-06-13 独立行政法人産業技術総合研究所 A novel functional peptide creation system that combines a random peptide library or a peptide library that mimics an antibody hypervariable region and an in vitro peptide selection method using RNA-binding proteins

Also Published As

Publication number Publication date
EP1309869A1 (en) 2003-05-14
CA2408652A1 (en) 2001-11-15
JP2003532431A (en) 2003-11-05
WO2001086293A8 (en) 2003-03-06
WO2001086293A2 (en) 2001-11-15

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