AU2002221492A1 - A method of purifying tetrodotoxin - Google Patents

A method of purifying tetrodotoxin

Info

Publication number
AU2002221492A1
AU2002221492A1 AU2002221492A AU2149202A AU2002221492A1 AU 2002221492 A1 AU2002221492 A1 AU 2002221492A1 AU 2002221492 A AU2002221492 A AU 2002221492A AU 2149202 A AU2149202 A AU 2149202A AU 2002221492 A1 AU2002221492 A1 AU 2002221492A1
Authority
AU
Australia
Prior art keywords
tetrodotoxin
purifying
purifying tetrodotoxin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002221492A
Inventor
Frank Hay Kong Shum
Maoqing Zhou
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nanning Maple Leaf Pharmaceutical Co Ltd
Original Assignee
Nanning Maple Leaf Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanning Maple Leaf Pharmaceutical Co Ltd filed Critical Nanning Maple Leaf Pharmaceutical Co Ltd
Publication of AU2002221492A1 publication Critical patent/AU2002221492A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
AU2002221492A 2000-11-22 2001-11-19 A method of purifying tetrodotoxin Abandoned AU2002221492A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN00132673 2000-11-22
CNB001326732A CN1187355C (en) 2000-11-22 2000-11-22 Method for refining high-purity tetradoxin
PCT/CN2001/001567 WO2002042308A1 (en) 2000-11-22 2001-11-19 A method of purifying tetrodotoxin

Publications (1)

Publication Number Publication Date
AU2002221492A1 true AU2002221492A1 (en) 2002-06-03

Family

ID=4595312

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002221492A Abandoned AU2002221492A1 (en) 2000-11-22 2001-11-19 A method of purifying tetrodotoxin

Country Status (6)

Country Link
US (1) US6562968B2 (en)
CN (1) CN1187355C (en)
AU (1) AU2002221492A1 (en)
DE (1) DE10197268T5 (en)
GB (1) GB0406277D0 (en)
WO (1) WO2002042308A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1568999A (en) * 2003-07-14 2005-01-26 南宁枫叶药业有限公司 Stable freeze dried formulation of spheroidine for medical use
EP1799220A1 (en) * 2004-09-22 2007-06-27 Laboratorios del Dr. Esteve S.A. Tetrodotoxin and its derivatives for the treatment of peripheral-nervously derived neuropathic pain
CN1323081C (en) * 2005-01-19 2007-06-27 南开大学 Preparation of tetraodotoxin by two-step resin method and tetraodotoxin preparation thereof
WO2007025212A2 (en) * 2005-08-25 2007-03-01 Wex Pharmaceuticals, Inc. Use of sodium channel blockers for the treatment of visceral pain or pain caused by cancer treatment
CA2619668A1 (en) * 2005-08-25 2007-03-01 Edge Renfeng Wang Use of sodium channel blockers for the management of musculoskeletal pain
EP1844781A1 (en) 2006-02-22 2007-10-17 Wex Pharmaceuticals Inc. Use of sodium channel blockers for the treatment of preterm labor
CN103271920A (en) * 2006-03-27 2013-09-04 威克斯医药有限公司 Use of sodium channel blockers for the treatment of neuropathic pain developing as a consequence of chemotherapy
US8486901B2 (en) * 2009-03-30 2013-07-16 Wex Medical Limited Sodium channel blocking compounds tetrodotoxin galactopyranosides
US20120310140A1 (en) 2010-12-01 2012-12-06 Spinal Modulation, Inc. Directed delivery of agents to neural anatomy
CN102445509B (en) * 2011-10-19 2013-05-08 南京师范大学 Reversed phase ion pair HPLC (high performance liquid chromatography) method for rapid trace detection of TTX (tetrodoxin) in fresh puffer fish blood
CN111122752B (en) * 2020-02-26 2022-06-10 浙江清华长三角研究院 Preparation method of tetrodotoxin component analysis standard substance

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601676B1 (en) 1986-07-17 1988-09-23 Rhone Poulenc Sante PROCESS FOR THE PREPARATION OF TAXOL AND DESACETYL-10 TAXOL
FR2629818B1 (en) 1988-04-06 1990-11-16 Centre Nat Rech Scient PROCESS FOR THE PREPARATION OF TAXOL
US5019504A (en) 1989-03-23 1991-05-28 The United States Of America As Represented By The Secretary Of Agriculture Production of taxol or taxol-like compounds in cell culture
MY110249A (en) 1989-05-31 1998-03-31 Univ Florida State Method for preparation of taxol using beta lactam
US5475120A (en) 1990-11-02 1995-12-12 University Of Florida Method for the isolation and purification of taxol and its natural analogues
US5451392A (en) 1992-03-03 1995-09-19 The Research And Development Institute At Montana State University Production of taxol
EP0627010A4 (en) 1992-12-07 1995-05-03 Univ Michigan PROCESS FOR THE ISOLATION AND PURIFICATION OF TAXOL AND TAXANES FROM -i(TAXUS) spp.
CN1058717C (en) * 1998-07-09 2000-11-22 河北省水产研究所 Extraction of anhydro tetraodotoxin

Also Published As

Publication number Publication date
US20020099226A1 (en) 2002-07-25
DE10197268T5 (en) 2005-02-24
US6562968B2 (en) 2003-05-13
CN1354176A (en) 2002-06-19
CN1187355C (en) 2005-02-02
WO2002042308A1 (en) 2002-05-30
GB0406277D0 (en) 2004-04-21

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