AU2001257174A1 - Integrin/adhesion antagonists - Google Patents
Integrin/adhesion antagonistsInfo
- Publication number
- AU2001257174A1 AU2001257174A1 AU2001257174A AU5717401A AU2001257174A1 AU 2001257174 A1 AU2001257174 A1 AU 2001257174A1 AU 2001257174 A AU2001257174 A AU 2001257174A AU 5717401 A AU5717401 A AU 5717401A AU 2001257174 A1 AU2001257174 A1 AU 2001257174A1
- Authority
- AU
- Australia
- Prior art keywords
- composition
- matter
- peptide
- seq
- domain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Classifications
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Physical Education & Sports Medicine (AREA)
- Hematology (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
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US19891900P | 2000-04-21 | 2000-04-21 | |
US60198919 | 2000-04-21 | ||
US20139400P | 2000-05-03 | 2000-05-03 | |
US60201394 | 2000-05-03 | ||
PCT/US2001/013069 WO2001081377A2 (fr) | 2000-04-21 | 2001-04-23 | Antagonistes d'integrine/d'adhesion |
Publications (1)
Publication Number | Publication Date |
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AU2001257174A1 true AU2001257174A1 (en) | 2001-11-07 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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AU2001257174A Abandoned AU2001257174A1 (en) | 2000-04-21 | 2001-04-23 | Integrin/adhesion antagonists |
Country Status (7)
Country | Link |
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US (1) | US20020168363A1 (fr) |
EP (1) | EP1274730A2 (fr) |
JP (1) | JP2003530871A (fr) |
AU (1) | AU2001257174A1 (fr) |
CA (1) | CA2407086A1 (fr) |
MX (1) | MXPA02010351A (fr) |
WO (1) | WO2001081377A2 (fr) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6887674B1 (en) | 1998-04-13 | 2005-05-03 | California Institute Of Technology | Artery- and vein-specific proteins and uses therefor |
WO2004078137A2 (fr) * | 2003-03-04 | 2004-09-16 | Greenville Hospital System | Agents antitumoraux comprenant une partie de ciblage et une partie de declenchement de reponse immunitaire |
JP4762889B2 (ja) | 2003-03-12 | 2011-08-31 | バスジーン セラピューティクス,インコーポレイテッド | 血管形成及び腫瘍成長を阻止するための核酸化合物 |
CN101072797B (zh) | 2004-03-12 | 2012-05-09 | 瓦斯基因治疗公司 | 结合ephb4、抑制血管发生和肿瘤生长的抗体 |
ATE492564T1 (de) | 2004-03-12 | 2011-01-15 | Vasgene Therapeutics Inc | Ephb4-bindende antikörper zur inhibierung von angiogenese und tumorwachstum |
US20050220760A1 (en) * | 2004-04-02 | 2005-10-06 | Clemson University | Novel immunotherapy |
EP1799713B1 (fr) | 2004-09-23 | 2014-11-05 | VasGene Therapeutics, Inc. | Composes de polypeptides pour l'inhibition de l'angiogenese et de croissance tumorale |
US8574577B2 (en) | 2008-01-03 | 2013-11-05 | The Scripps Research Institute | VEGF antibodies comprising modular recognition domains |
EP2237797A4 (fr) | 2008-01-03 | 2012-11-07 | Scripps Research Inst | Ciblage d'anticorps par domaine de reconnaissance modulaire |
US8454960B2 (en) | 2008-01-03 | 2013-06-04 | The Scripps Research Institute | Multispecific antibody targeting and multivalency through modular recognition domains |
US8557242B2 (en) | 2008-01-03 | 2013-10-15 | The Scripps Research Institute | ERBB2 antibodies comprising modular recognition domains |
US8557243B2 (en) | 2008-01-03 | 2013-10-15 | The Scripps Research Institute | EFGR antibodies comprising modular recognition domains |
US20120100166A1 (en) | 2010-07-15 | 2012-04-26 | Zyngenia, Inc. | Ang-2 Binding Complexes and Uses Thereof |
AU2012258637B2 (en) | 2011-05-24 | 2017-07-20 | Zyngenia, Inc. | Multivalent and monovalent multispecific complexes and their uses |
CN105451767B (zh) | 2013-03-15 | 2019-10-18 | 泽恩格尼亚股份有限公司 | 多价和单价多特异性复合物及其用途 |
WO2017158168A1 (fr) * | 2016-03-18 | 2017-09-21 | Fundació Institut De Bioenginyeria De Catalunya (Ibec) | Inhibiteurs de liaison taline-vinculine pour le traitement du cancer |
JP7291624B2 (ja) * | 2016-11-01 | 2023-06-15 | アローヘッド ファーマシューティカルズ インコーポレイテッド | アルファ-vベータ-6インテグリンリガンド及びその使用 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5981478A (en) * | 1993-11-24 | 1999-11-09 | La Jolla Cancer Research Foundation | Integrin-binding peptides |
US5510332A (en) * | 1994-07-07 | 1996-04-23 | Texas Biotechnology Corporation | Process to inhibit binding of the integrin α4 62 1 to VCAM-1 or fibronectin and linear peptides therefor |
EP0727225A3 (fr) * | 1995-02-14 | 1997-01-15 | Sonus Pharma Inc | Compositions et méthodes pour l'imagerie ultrasonique dirigée |
EP0906419A2 (fr) * | 1996-03-28 | 1999-04-07 | Chiron Corporation | Ligands peptidiques du recepteur de l'urokinase |
PT954588E (pt) * | 1996-12-20 | 2007-03-30 | Amgen Inc | Composições que contêm uma proteína de fusão ob e métodos para a sua preparação e utilização |
ES2388341T3 (es) * | 1998-10-23 | 2012-10-11 | Kirin-Amgen Inc. | Péptidos miméticos de trombopoyetina diméricos que se unen al receptor MPL y que tienen actividad trombopoyética |
DE60127656T2 (de) * | 2000-02-25 | 2007-12-20 | Immunex Corp., Seattle | Integrin antagonisten |
ES2260219T3 (es) * | 2000-04-21 | 2006-11-01 | Amgen Inc. | Derivados de peptidos apo-ai/aii. |
-
2001
- 2001-04-23 JP JP2001578464A patent/JP2003530871A/ja not_active Withdrawn
- 2001-04-23 CA CA002407086A patent/CA2407086A1/fr not_active Abandoned
- 2001-04-23 MX MXPA02010351A patent/MXPA02010351A/es unknown
- 2001-04-23 EP EP01930665A patent/EP1274730A2/fr not_active Withdrawn
- 2001-04-23 AU AU2001257174A patent/AU2001257174A1/en not_active Abandoned
- 2001-04-23 WO PCT/US2001/013069 patent/WO2001081377A2/fr active Application Filing
- 2001-04-23 US US09/840,277 patent/US20020168363A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1274730A2 (fr) | 2003-01-15 |
WO2001081377A2 (fr) | 2001-11-01 |
CA2407086A1 (fr) | 2001-11-01 |
MXPA02010351A (es) | 2003-04-25 |
US20020168363A1 (en) | 2002-11-14 |
WO2001081377A3 (fr) | 2002-07-18 |
JP2003530871A (ja) | 2003-10-21 |
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