AU2001247968A1 - Use of asiatic acid or asiaticoside for treatment of cancer - Google Patents

Use of asiatic acid or asiaticoside for treatment of cancer

Info

Publication number
AU2001247968A1
AU2001247968A1 AU2001247968A AU4796801A AU2001247968A1 AU 2001247968 A1 AU2001247968 A1 AU 2001247968A1 AU 2001247968 A AU2001247968 A AU 2001247968A AU 4796801 A AU4796801 A AU 4796801A AU 2001247968 A1 AU2001247968 A1 AU 2001247968A1
Authority
AU
Australia
Prior art keywords
asiaticoside
cancer
treatment
asiatic acid
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001247968A
Other languages
English (en)
Inventor
Azizol Abdul Kadir
Lean Teik Ng
Se-Kyung Oh
Chokyun Rha
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Government of Malaysia
Massachusetts Institute of Technology
Original Assignee
Government of Malaysia
Massachusetts Institute of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Government of Malaysia, Massachusetts Institute of Technology filed Critical Government of Malaysia
Publication of AU2001247968A1 publication Critical patent/AU2001247968A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/739—Lipopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7012—Compounds having a free or esterified carboxyl group attached, directly or through a carbon chain, to a carbon atom of the saccharide radical, e.g. glucuronic acid, neuraminic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
AU2001247968A 2000-08-29 2001-02-14 Use of asiatic acid or asiaticoside for treatment of cancer Abandoned AU2001247968A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
MYPI20003987A MY138883A (en) 2000-08-29 2000-08-29 Use of asiatic acid for treatment of cencer
MYPI20003987 2000-08-29
PCT/US2001/040103 WO2002017904A1 (en) 2000-08-29 2001-02-14 Use of asiatic acid or asiaticoside for treatment of cancer

Publications (1)

Publication Number Publication Date
AU2001247968A1 true AU2001247968A1 (en) 2002-03-13

Family

ID=19749475

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001247968A Abandoned AU2001247968A1 (en) 2000-08-29 2001-02-14 Use of asiatic acid or asiaticoside for treatment of cancer

Country Status (9)

Country Link
US (1) US20040097463A1 (de)
EP (1) EP1313462B1 (de)
JP (2) JP2004507496A (de)
AT (1) ATE415962T1 (de)
AU (1) AU2001247968A1 (de)
DE (1) DE60136826D1 (de)
DK (1) DK1313462T3 (de)
MY (1) MY138883A (de)
WO (1) WO2002017904A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030144312A1 (en) * 2001-10-30 2003-07-31 Schoenhard Grant L. Inhibitors of ABC drug transporters in multidrug resistant cancer cells
KR100571886B1 (ko) 2004-02-23 2006-04-17 학교법인 영남학원 아시아틱산을 포함하는 피부암 예방 또는 치료용 조성물
EP1737493B1 (de) 2004-02-25 2011-06-29 Dana-Farber Cancer Institute, Inc. Hemmer des insulinartigen wachstumsfaktor-rezeptors-1 zur hemmung von tumorzellwachstum
WO2006012015A2 (en) * 2004-06-29 2006-02-02 Oregon Health And Science University Methods and compositions for nerve regeneration
US20070010459A1 (en) * 2005-01-14 2007-01-11 Ying Liu Application of asiatic acid and its derivatives to treat pulmonary fibrosis
CA2595749A1 (en) * 2005-01-27 2006-08-03 Research Development Foundation Combination therapy with triterpenoid compounds and proteasome inhibitors
US8742167B2 (en) 2008-01-11 2014-06-03 Shanghai Institute Of Pharmaceutical Industry Therapeutic formulations based on asiatic acid and selected salts thereof
CA2721506C (en) 2008-04-16 2019-09-17 Jun Luo Compositions and methods for treating or preventing prostate cancer and for detecting androgen receptor variants
WO2009148623A2 (en) 2008-06-05 2009-12-10 Stc.Unm Methods and related compositions for the treatment of cancer
US9108372B2 (en) 2009-12-21 2015-08-18 Pirelli Tyre S.P.A. Process and plant for building tyres
JP5913297B2 (ja) 2010-06-10 2016-04-27 インダス バイオテック プライベート リミティド センテラ・アジアティカからの高純度アジアチコサイドの製造法及びその使用法
EP2649994B1 (de) * 2011-01-31 2017-08-30 LUCOLAS-M.D. Ltd. Kombinationen von aromatase inhibitoren und antioxidanzien
US20140194368A1 (en) * 2013-01-04 2014-07-10 Beech Tree Labs, Inc. Method of Treating Cancer by Administration of Low Levels of Heat Shock Protein 70 (HSP70)
CA2904170A1 (en) 2013-03-14 2014-09-25 University Of Maryland, Baltimore Androgen receptor down-regulating agents and uses thereof
AU2014306698A1 (en) 2013-08-12 2016-01-28 Tokai Pharmaceuticals, Inc. Biomarkers for treatment of neoplastic disorders using androgen-targeted therapies
EP3146081B1 (de) 2014-05-19 2020-10-28 The Johns Hopkins University Verfahren zur identifizierung von androgenrezeptorspleissvarianten bei patienten mit kastrationsresistentem prostatakrebs
WO2016033114A1 (en) * 2014-08-25 2016-03-03 The Johns Hopkins University Methods and compositions related to prostate cancer therapeutics
EP3124047A1 (de) * 2015-07-28 2017-02-01 Merz Pharma GmbH & Co. KGaA Pentacyclische triterpene zur injektionslipolyse
US20180228815A1 (en) * 2016-11-09 2018-08-16 The Chinese University Of Hong Kong Naringenin and asiatic acid combination treatment of cancers
WO2019200585A1 (en) * 2018-04-19 2019-10-24 The Chinese University Of Hong Kong Naringenin and asiatic acid combination treatment of cancers
CN109528735B (zh) * 2019-01-30 2021-03-12 中国药科大学 积雪草苷在制备治疗皮肤癌药物中的新用途
CN110200981A (zh) * 2019-06-06 2019-09-06 中国药科大学 五环三萜皂苷的医药用途及其药物组合物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB923414A (en) * 1960-04-13 1963-04-10 Laroche Navarron Lab Therapeutic compositions comprising asiatic and arjunolic acids
IT1203515B (it) * 1987-02-26 1989-02-15 Indena Spa Complessi di saponine con fosfolipidi e composizioni farmaceutiche e cosmetiche che li contengono
EP0383171A3 (de) * 1989-02-11 1991-07-24 Hoechst Aktiengesellschaft 2,3,23-Trihydroxy-urs-12-en Derivate zur Behandlung von Kognitiven Störungen
FR2714598B1 (fr) * 1993-12-30 1996-02-09 Oreal Composition amincissante à deux types de liposomes pour traitement topique, son utilisation.
JPH08133952A (ja) * 1994-11-07 1996-05-28 Shiseido Co Ltd 皮膚外用剤
WO1998023575A1 (en) * 1996-11-27 1998-06-04 Dong Kook Pharmaceutical Co., Ltd. Asiatic acid derivatives having modified a-ring
IT1288257B1 (it) * 1996-11-29 1998-09-11 Paoli Ambrosi Gianfranco De Composizione per uso cosmetico,farmaceutico o dietetico a base di un aminozucchero e/o di un acido poliidrossilico
FR2763336B1 (fr) * 1997-05-14 1999-08-06 Lvmh Rech Esters de tocopherol et leurs utilisations en cosmetique et pharmacie
EP1765328B1 (de) * 2004-06-14 2011-11-23 Zoser B. Salama Antikrebs-zusammensetzung mit prolin bzw. prolinderivaten und einem antitumorantikörper

Also Published As

Publication number Publication date
MY138883A (en) 2009-08-28
ATE415962T1 (de) 2008-12-15
JP2012092110A (ja) 2012-05-17
JP2004507496A (ja) 2004-03-11
US20040097463A1 (en) 2004-05-20
DK1313462T3 (da) 2009-03-30
EP1313462A1 (de) 2003-05-28
JP5421340B2 (ja) 2014-02-19
EP1313462B1 (de) 2008-12-03
DE60136826D1 (de) 2009-01-15
WO2002017904A1 (en) 2002-03-07

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