AU2001247675A1 - Binding compounds and methods for identifying binding compounds - Google Patents

Binding compounds and methods for identifying binding compounds

Info

Publication number
AU2001247675A1
AU2001247675A1 AU2001247675A AU4767501A AU2001247675A1 AU 2001247675 A1 AU2001247675 A1 AU 2001247675A1 AU 2001247675 A AU2001247675 A AU 2001247675A AU 4767501 A AU4767501 A AU 4767501A AU 2001247675 A1 AU2001247675 A1 AU 2001247675A1
Authority
AU
Australia
Prior art keywords
molecule
binding
chemokine receptor
cxc chemokine
cxcr4
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001247675A
Other languages
English (en)
Inventor
Steven A. Kates
John J. Nestor
Christina A. Tan Hehir
Carol J. Wilson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Consensus Pharmaceuticals Inc
Original Assignee
Consensus Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/813,448 external-priority patent/US20020142346A1/en
Priority claimed from US09/813,653 external-priority patent/US20020064770A1/en
Priority claimed from US09/813,651 external-priority patent/US20030018438A1/en
Application filed by Consensus Pharmaceuticals Inc filed Critical Consensus Pharmaceuticals Inc
Publication of AU2001247675A1 publication Critical patent/AU2001247675A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7158—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for chemokines
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/20—Screening for compounds of potential therapeutic value cell-free systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • AIDS & HIV (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
AU2001247675A 2000-03-21 2001-03-21 Binding compounds and methods for identifying binding compounds Abandoned AU2001247675A1 (en)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US19129900P 2000-03-21 2000-03-21
US19094600P 2000-03-21 2000-03-21
US19099600P 2000-03-21 2000-03-21
US60191299 2000-03-21
US60190946 2000-03-21
US60190996 2000-03-21
US09813651 2001-03-20
US09/813,448 US20020142346A1 (en) 2000-03-21 2001-03-20 Binding compounds and methods for identifying binding compounds
US09813653 2001-03-20
US09/813,653 US20020064770A1 (en) 2000-03-21 2001-03-20 Binding compounds and methods for identifying binding compounds
US09/813,651 US20030018438A1 (en) 2000-03-21 2001-03-20 Binding compounds and methods for identifying binding compounds
US09813448 2001-03-20
PCT/US2001/009160 WO2001070768A2 (en) 2000-03-21 2001-03-21 Receptor-binding compounds and method for identifying them

Publications (1)

Publication Number Publication Date
AU2001247675A1 true AU2001247675A1 (en) 2001-10-03

Family

ID=27558818

Family Applications (3)

Application Number Title Priority Date Filing Date
AU2001247675A Abandoned AU2001247675A1 (en) 2000-03-21 2001-03-21 Binding compounds and methods for identifying binding compounds
AU2001253870A Abandoned AU2001253870A1 (en) 2000-03-21 2001-03-21 Receptor-binding compounds and methods for identifying them
AU2001247674A Abandoned AU2001247674A1 (en) 2000-03-21 2001-03-21 Binding compounds and methods for identifying binding compounds

Family Applications After (2)

Application Number Title Priority Date Filing Date
AU2001253870A Abandoned AU2001253870A1 (en) 2000-03-21 2001-03-21 Receptor-binding compounds and methods for identifying them
AU2001247674A Abandoned AU2001247674A1 (en) 2000-03-21 2001-03-21 Binding compounds and methods for identifying binding compounds

Country Status (5)

Country Link
EP (3) EP1268521A1 (ja)
JP (2) JP2004502134A (ja)
AU (3) AU2001247675A1 (ja)
CA (3) CA2404139A1 (ja)
WO (3) WO2001070768A2 (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005056581A2 (en) * 2003-12-10 2005-06-23 Universite De Lausanne Peptide able to specifically bind a chemokine receptor and use thereof
EP1797428A1 (en) * 2004-10-04 2007-06-20 Alchemia Pty Ltd Selective inhibitors
GB0724860D0 (en) * 2007-12-20 2008-01-30 Heptares Therapeutics Ltd Screening
US8409837B2 (en) * 2010-08-19 2013-04-02 Probiodrug Ag Crystal structure of glutaminyl cyclase

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5532167A (en) * 1994-01-07 1996-07-02 Beth Israel Hospital Substrate specificity of protein kinases

Also Published As

Publication number Publication date
EP1268523A2 (en) 2003-01-02
WO2001071346A3 (en) 2002-09-12
JP2004502134A (ja) 2004-01-22
CA2403784A1 (en) 2001-09-27
WO2001070765A9 (en) 2003-02-06
WO2001070765A1 (en) 2001-09-27
CA2404139A1 (en) 2001-09-27
EP1268520A2 (en) 2003-01-02
EP1268521A1 (en) 2003-01-02
JP2003528319A (ja) 2003-09-24
WO2001071346A2 (en) 2001-09-27
WO2001070768A3 (en) 2002-03-14
AU2001247674A1 (en) 2001-10-03
WO2001070768A2 (en) 2001-09-27
AU2001253870A1 (en) 2001-10-03
CA2403788A1 (en) 2001-09-27

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