AU2001244711A1 - Tlr/cd14 binding inhibitor - Google Patents
Tlr/cd14 binding inhibitorInfo
- Publication number
- AU2001244711A1 AU2001244711A1 AU2001244711A AU4471101A AU2001244711A1 AU 2001244711 A1 AU2001244711 A1 AU 2001244711A1 AU 2001244711 A AU2001244711 A AU 2001244711A AU 4471101 A AU4471101 A AU 4471101A AU 2001244711 A1 AU2001244711 A1 AU 2001244711A1
- Authority
- AU
- Australia
- Prior art keywords
- tlr
- binding inhibitor
- inhibitor
- binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000099617 | 2000-03-31 | ||
JP2000-99617 | 2000-03-31 | ||
US09/806,158 US6916628B1 (en) | 1999-09-17 | 2000-09-18 | Method for the measurement of soluble CD14 proteins separately |
JP2000356719 | 2000-11-22 | ||
JP2000-356719 | 2000-11-22 | ||
US09806158 | 2001-03-28 | ||
PCT/JP2001/002869 WO2001072993A1 (fr) | 2000-03-31 | 2001-04-02 | Inhibiteur de liaison entre le recepteur de type toll et cd14 |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001244711A1 true AU2001244711A1 (en) | 2001-10-08 |
Family
ID=27342946
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001244711A Abandoned AU2001244711A1 (en) | 2000-03-31 | 2001-04-02 | Tlr/cd14 binding inhibitor |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1275713A4 (de) |
AU (1) | AU2001244711A1 (de) |
CA (1) | CA2404511A1 (de) |
WO (1) | WO2001072993A1 (de) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030125272A1 (en) * | 2001-11-19 | 2003-07-03 | Karras James G. | Antisense modulation of toll-like receptor 4 expression |
US6303321B1 (en) | 1999-02-11 | 2001-10-16 | North Shore-Long Island Jewish Research Institute | Methods for diagnosing sepsis |
US6916628B1 (en) | 1999-09-17 | 2005-07-12 | Mochida Pharmaceutical Co., Ltd. | Method for the measurement of soluble CD14 proteins separately |
US7220723B2 (en) | 2001-05-15 | 2007-05-22 | The Feinstein Institute For Medical Research | Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents |
US7304034B2 (en) | 2001-05-15 | 2007-12-04 | The Feinstein Institute For Medical Research | Use of HMGB fragments as anti-inflammatory agents |
US7608684B2 (en) | 2002-11-12 | 2009-10-27 | Mochida Pharmaceuticals Co., Ltd. | Soluble CD14 antigen |
DE60331677D1 (de) | 2002-11-12 | 2010-04-22 | Mochida Pharm Co Ltd | Kit zur untersuchung von menschlichem niedermolekulargewicht cd14 und antikörper |
EP1628530B8 (de) * | 2003-05-15 | 2012-08-01 | Genentech, Inc. | Verfahren und zubereitungen zur vorbeugung und behandlung von sepsis |
AU2003271835A1 (en) * | 2003-06-06 | 2005-01-04 | Avecia Limited | Process for the separation of proteins |
US7696169B2 (en) | 2003-06-06 | 2010-04-13 | The Feinstein Institute For Medical Research | Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents |
CA2538763C (en) | 2003-09-11 | 2015-05-05 | Critical Therapeutics, Inc. | Monoclonal antibodies against hmgb1 |
JP2005137333A (ja) * | 2003-11-10 | 2005-06-02 | Japan Science & Technology Agency | Tbk1ノックアウトマウスを用いたスクリーニング方法 |
EP1746104B1 (de) | 2004-05-11 | 2013-03-20 | Mochida Pharmaceutical Co., Ltd. | Neues lösliches cd14-antigen |
CN101189334B (zh) | 2005-06-03 | 2013-11-06 | 持田制药株式会社 | 抗cd14抗体融合蛋白质 |
US7625555B2 (en) | 2007-06-18 | 2009-12-01 | Novagen Holding Corporation | Recombinant human interferon-like proteins |
GB0815673D0 (en) * | 2008-08-28 | 2008-10-08 | Univ Cardiff | Peptides |
WO2010033294A1 (en) | 2008-09-22 | 2010-03-25 | Cedars-Sinai Medical Center | Short-form human md-2 as a negative regulator of toll-like receptor 4 signaling |
US9512196B2 (en) | 2008-09-22 | 2016-12-06 | Cedars-Sinai Medical Center | Short-form human MD-2 as a negative regulator of toll-like receptor 4 signaling |
US8765370B2 (en) * | 2009-06-11 | 2014-07-01 | Scinopharm Taiwan, Ltd | Inhibition-based high-throughput screen strategy for cell clones |
CN116444673B (zh) * | 2023-06-14 | 2023-09-15 | 北京汇智和源生物技术有限公司 | 人源膜cd14单克隆抗体及其制备方法和应用 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5543303A (en) * | 1988-11-28 | 1996-08-06 | Goyert; Sanna M. | Recombinant myelomonocytic differentiation antigen CD14 |
US5705398A (en) * | 1994-03-02 | 1998-01-06 | The Scripps Research Institute | Methods for identifying inhibitors of LPS-mediated LBP binding |
DE69534601T2 (de) * | 1994-09-16 | 2006-08-03 | The Scripps Research Institute, La Jolla | Gebrauch von antikörpern zur verhinderung von auswirkungen hervorgerufen durch grampositive- und myko-bakterien |
WO1999061468A2 (en) * | 1998-05-27 | 1999-12-02 | Gemma Biotechnology Ltd. | The induction of antibiotic peptides by lait (scd14) protein |
JP2000086699A (ja) * | 1998-09-07 | 2000-03-28 | Seikagaku Kogyo Co Ltd | 細胞表面抗原cd14を認識する新規なモノクローナル抗体 |
-
2001
- 2001-04-02 WO PCT/JP2001/002869 patent/WO2001072993A1/ja not_active Application Discontinuation
- 2001-04-02 EP EP01917790A patent/EP1275713A4/de not_active Withdrawn
- 2001-04-02 AU AU2001244711A patent/AU2001244711A1/en not_active Abandoned
- 2001-04-02 CA CA002404511A patent/CA2404511A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2001072993A1 (fr) | 2001-10-04 |
EP1275713A4 (de) | 2004-06-30 |
CA2404511A1 (en) | 2001-10-04 |
EP1275713A1 (de) | 2003-01-15 |
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