AU2001231745A1 - Method and device for producing shaped microbial cellulose for use as biomaterial, especially for microsurgery - Google Patents
Method and device for producing shaped microbial cellulose for use as biomaterial, especially for microsurgeryInfo
- Publication number
- AU2001231745A1 AU2001231745A1 AU2001231745A AU3174501A AU2001231745A1 AU 2001231745 A1 AU2001231745 A1 AU 2001231745A1 AU 2001231745 A AU2001231745 A AU 2001231745A AU 3174501 A AU3174501 A AU 3174501A AU 2001231745 A1 AU2001231745 A1 AU 2001231745A1
- Authority
- AU
- Australia
- Prior art keywords
- biomaterial
- shaped body
- thrombosis
- blood vessels
- prosthesis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
- C08L1/02—Cellulose; Modified cellulose
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Materials For Medical Uses (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Prostheses (AREA)
Abstract
The use of exogenic materials for replacing blood vessels carries the risk of thrombosis and is therefore particularly unsuitable for microsurgical applications (inner vessel diameters of 1-3 mm and less), or only suitable under certain conditions. Replacements of blood vessels with a very small lumen in particular require biomaterials which guarantee that the surfaces of the prosthesis that come into contact with the blood are of a very high quality, and which reliably avoid this kind of thrombosis adhesion. The biomaterial is produced by immersing shaped body walls, especially of a glass matrix consisting of a glass tube and glass body, in a container of an inoculated nutrient solution so that the inoculated nutrient solution is drawn into the area between the walls of the shaped body and cultivation takes place in a moist, aerobic environment. In each subsequent cultivation process, an unused shaped body (glass body) is used as the shaped body wall for shaping the surface of the prosthesis material that is to come into contact with the blood when the biomaterial is used. This is the only sure way of reproducing the high surface quality of the vessel prosthesis and hereby reliably preventing thrombosis adhesion on the biomaterial used. The inventive method is particularly suitable for microsurgical applications, especially for replacing blood vessels and other internal hollow organs or as a cuff for covering nerve fibres, etc.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10007798 | 2000-02-17 | ||
DE10007798 | 2000-02-17 | ||
PCT/EP2001/001621 WO2001061026A1 (en) | 2000-02-17 | 2001-02-13 | Method and device for producing shaped microbial cellulose for use as biomaterial, especially for microsurgery |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001231745A1 true AU2001231745A1 (en) | 2001-08-27 |
Family
ID=7631674
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001231745A Abandoned AU2001231745A1 (en) | 2000-02-17 | 2001-02-13 | Method and device for producing shaped microbial cellulose for use as biomaterial, especially for microsurgery |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1263980B1 (en) |
JP (1) | JP2003525039A (en) |
CN (1) | CN100451125C (en) |
AT (1) | ATE394500T1 (en) |
AU (1) | AU2001231745A1 (en) |
CA (1) | CA2400372A1 (en) |
DE (1) | DE50113938D1 (en) |
WO (1) | WO2001061026A1 (en) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102006007412B4 (en) * | 2006-02-19 | 2008-08-21 | Bioregeneration Gmbh | Process for producing an elongated cellulose hollow body |
JP2010505460A (en) * | 2006-10-02 | 2010-02-25 | アルテリオン アーベー | Process for the preparation of hollow cellulose tubes by culturing microorganisms producing cellulose on the surface of the hollow carrier and feeding a gas having an oxygen level of at least 35% |
DE102007006844B4 (en) * | 2007-02-12 | 2014-06-12 | Bioregeneration Gmbh | Elongated hollow body for replacement of a venous blood vessel and method and mold for producing a crystalline cellulose comprising elongated hollow body |
DE102007006843A1 (en) | 2007-02-12 | 2008-08-14 | Bioregeneration Gmbh | Method and support structure for cultivating living cells |
DE102007016852A1 (en) * | 2007-04-10 | 2008-10-16 | Bioregeneration Gmbh | Process for producing a structure comprising crystalline cellulose |
DE102007020726A1 (en) | 2007-05-03 | 2008-11-20 | Robert Dr. Simmoteit | Overlay and case |
US7832857B2 (en) | 2008-08-18 | 2010-11-16 | Levinson Dennis J | Microbial cellulose contact lens |
DE102008056413B4 (en) * | 2008-11-07 | 2014-12-24 | Bioregeneration Gmbh | Process for producing a cellulose-containing body |
DE102009003890A1 (en) | 2009-01-02 | 2010-07-08 | Bioregeneration Gmbh | Apparatus comprising a device and a liner implantable in a vessel of the body of a patient, and methods of making same |
WO2011038373A2 (en) | 2009-09-28 | 2011-03-31 | Virginia Tech Intellectual Properties, Inc. | Three-dimensional bioprinting of biosynthetic cellulose (bc) implants and scaffolds for tissue engineering |
TWI408232B (en) | 2010-05-24 | 2013-09-11 | Nympheas Internationalcorp | Bacterial cellulose film, and use thereof |
CN101921700B (en) * | 2010-09-02 | 2015-03-11 | 东华大学 | Device and method for preparing hollow heteromorphic bacteria cellulose material |
CN101914434B (en) * | 2010-09-02 | 2015-01-07 | 东华大学 | Device and method for dynamically preparing heterocavity bacterium cellulose materials |
DE102012201272B4 (en) | 2012-01-30 | 2019-05-09 | Kkf Ug | Apparatus for producing microbial polymer hollow bodies |
WO2013113675A1 (en) | 2012-01-30 | 2013-08-08 | Kkf Ug | Process for producing hollow bodies from microbial cellulose |
DE102012201268B4 (en) | 2012-01-30 | 2021-01-21 | Kkf Ug | Process for the production of hollow bodies from microbial cellulose |
CN102641161B (en) * | 2012-04-23 | 2016-06-08 | 东华大学 | A kind of artificial blood vessel with composite structure and dynamic preparation method thereof |
CN105505774B (en) * | 2016-01-20 | 2017-07-18 | 重庆大学 | Tissue engineering artificial blood vessel culture experiment device and its application method |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ214417A (en) * | 1984-12-21 | 1988-06-30 | Univ Texas | Microbially produced cellulose |
JPH03272772A (en) * | 1989-04-28 | 1991-12-04 | Ajinomoto Co Inc | Hollow microorganism cellulose, its manufacture, and artificial blood vessel made of cellulose |
EP0396344A3 (en) * | 1989-04-28 | 1991-04-03 | Ajinomoto Co., Inc. | Hollow microbial cellulose, process for preparation thereof, and artificial blood vessel formed of said cellulose |
DE4322966C2 (en) * | 1993-07-09 | 1995-10-26 | Rhodia Ag Rhone Poulenc | Cellulose acetate molded structures and their use as filter tow and tobacco smoke filter element |
JPH08126697A (en) * | 1994-10-31 | 1996-05-21 | Ajinomoto Co Inc | Manufacture of hollow microorganism cellulose tube |
US5882357A (en) * | 1996-09-13 | 1999-03-16 | The Regents Of The University Of California | Durable and regenerable microbiocidal textiles |
-
2001
- 2001-02-13 AU AU2001231745A patent/AU2001231745A1/en not_active Abandoned
- 2001-02-13 AT AT01903766T patent/ATE394500T1/en not_active IP Right Cessation
- 2001-02-13 DE DE50113938T patent/DE50113938D1/en not_active Expired - Lifetime
- 2001-02-13 CA CA002400372A patent/CA2400372A1/en not_active Abandoned
- 2001-02-13 WO PCT/EP2001/001621 patent/WO2001061026A1/en active IP Right Grant
- 2001-02-13 CN CNB018051537A patent/CN100451125C/en not_active Expired - Fee Related
- 2001-02-13 JP JP2001559863A patent/JP2003525039A/en active Pending
- 2001-02-13 EP EP01903766A patent/EP1263980B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2400372A1 (en) | 2001-08-23 |
JP2003525039A (en) | 2003-08-26 |
EP1263980A1 (en) | 2002-12-11 |
WO2001061026A1 (en) | 2001-08-23 |
CN100451125C (en) | 2009-01-14 |
DE50113938D1 (en) | 2008-06-19 |
ATE394500T1 (en) | 2008-05-15 |
EP1263980B1 (en) | 2008-05-07 |
CN1401005A (en) | 2003-03-05 |
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