AU1991801A - 1-aziridino-1-hydroxyiminomethyl-derivatives, method for the production thereof and medicaments containing said compounds - Google Patents
1-aziridino-1-hydroxyiminomethyl-derivatives, method for the production thereof and medicaments containing said compoundsInfo
- Publication number
- AU1991801A AU1991801A AU19918/01A AU1991801A AU1991801A AU 1991801 A AU1991801 A AU 1991801A AU 19918/01 A AU19918/01 A AU 19918/01A AU 1991801 A AU1991801 A AU 1991801A AU 1991801 A AU1991801 A AU 1991801A
- Authority
- AU
- Australia
- Prior art keywords
- sub
- aziridino
- compounds
- hydroxyiminomethyl
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000005647 linker group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
- C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D203/08—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
- C07D203/12—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19947440A DE19947440A1 (de) | 1999-09-24 | 1999-09-24 | 1-Aziridino-1-hydroxyiminomethyl-Derivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
| DE19947440 | 1999-09-24 | ||
| PCT/DE2000/003441 WO2001021585A2 (de) | 1999-09-24 | 2000-09-22 | Bis-(aziridino-1-hydroxyiminomethyl)-derivate, verfahren zu deren herstellung und deren verwendung als antitumormittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU1991801A true AU1991801A (en) | 2001-04-24 |
Family
ID=7924241
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU19918/01A Abandoned AU1991801A (en) | 1999-09-24 | 2000-09-22 | 1-aziridino-1-hydroxyiminomethyl-derivatives, method for the production thereof and medicaments containing said compounds |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7078418B1 (enExample) |
| EP (1) | EP1220838B1 (enExample) |
| JP (1) | JP4860865B2 (enExample) |
| AT (1) | ATE486847T1 (enExample) |
| AU (1) | AU1991801A (enExample) |
| CZ (1) | CZ303316B6 (enExample) |
| DE (3) | DE19947440A1 (enExample) |
| ES (1) | ES2355058T3 (enExample) |
| HU (1) | HUP0203463A3 (enExample) |
| PL (1) | PL204282B1 (enExample) |
| RU (1) | RU2264397C2 (enExample) |
| WO (1) | WO2001021585A2 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104628619A (zh) * | 2015-02-02 | 2015-05-20 | 东力（南通）化工有限公司 | 一种细胞生长抑制剂抗癌药雷阿卡啶及相关衍生物的制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4617398A (en) * | 1982-04-12 | 1986-10-14 | The Research Foundation Of State University Of New York | Phosphoaziridine compounds useful for treatment of tumors |
| NL8301626A (nl) * | 1983-05-06 | 1984-12-03 | Rijksuniversiteit | Aziridinoderivaat van een tetramere cyclochloorfosfazeenverbinding, werkwijze ter bereiding daarvan, en een door substitutie van de chlooratomen van de tetramere chloorfosfazeenverbinding afgeleid aziridinoderivaat. |
| US4806531A (en) * | 1986-02-20 | 1989-02-21 | Yale University | 2,3-bis(aziridinyl)-1,4-naphthoquinone sulfonate derivatives having antineoplastic activity |
| US5612329A (en) * | 1995-06-05 | 1997-03-18 | University Of Maryland At Baltimore | Diaziridinylpolyamine anti-cancer agents |
-
1999
- 1999-09-24 DE DE19947440A patent/DE19947440A1/de not_active Withdrawn
-
2000
- 2000-09-22 HU HU0203463A patent/HUP0203463A3/hu unknown
- 2000-09-22 AU AU19918/01A patent/AU1991801A/en not_active Abandoned
- 2000-09-22 US US10/089,039 patent/US7078418B1/en not_active Expired - Fee Related
- 2000-09-22 RU RU2002110105/04A patent/RU2264397C2/ru not_active IP Right Cessation
- 2000-09-22 ES ES00982943T patent/ES2355058T3/es not_active Expired - Lifetime
- 2000-09-22 DE DE50016022T patent/DE50016022D1/de not_active Expired - Lifetime
- 2000-09-22 PL PL353863A patent/PL204282B1/pl not_active IP Right Cessation
- 2000-09-22 AT AT00982943T patent/ATE486847T1/de active
- 2000-09-22 WO PCT/DE2000/003441 patent/WO2001021585A2/de not_active Ceased
- 2000-09-22 DE DE10082858T patent/DE10082858D2/de not_active Expired - Lifetime
- 2000-09-22 CZ CZ20021351A patent/CZ303316B6/cs not_active IP Right Cessation
- 2000-09-22 JP JP2001524965A patent/JP4860865B2/ja not_active Expired - Fee Related
- 2000-09-22 EP EP00982943A patent/EP1220838B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ATE486847T1 (de) | 2010-11-15 |
| CZ303316B6 (cs) | 2012-08-01 |
| HUP0203463A3 (en) | 2003-11-28 |
| PL353863A1 (en) | 2003-12-01 |
| WO2001021585A3 (de) | 2001-10-11 |
| PL204282B1 (pl) | 2009-12-31 |
| EP1220838B1 (de) | 2010-11-03 |
| ES2355058T3 (es) | 2011-03-22 |
| WO2001021585A2 (de) | 2001-03-29 |
| JP2003509489A (ja) | 2003-03-11 |
| US7078418B1 (en) | 2006-07-18 |
| JP4860865B2 (ja) | 2012-01-25 |
| HUP0203463A2 (hu) | 2003-02-28 |
| RU2264397C2 (ru) | 2005-11-20 |
| CZ20021351A3 (cs) | 2002-07-17 |
| DE50016022D1 (de) | 2010-12-16 |
| DE19947440A1 (de) | 2001-04-05 |
| EP1220838A2 (de) | 2002-07-10 |
| DE10082858D2 (de) | 2002-02-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase | ||
| TH | Corrigenda |
Free format text: IN VOL 15, NO 28, PAGE(S) 5860-5863 UNDER THE HEADING APPLICATIONS LAPSED, REFUSED OR WITHDRAWN PLEASE DELETE ALL REFERENCE TO APPLICATION NO. 70335/00, 77611/00, 16452/01 AND 19918/01 |
|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |