AU1455500A - Oxadiazole, thiadiazole and triazole derivatives and combinatorial libraries thereof - Google Patents

Oxadiazole, thiadiazole and triazole derivatives and combinatorial libraries thereof

Info

Publication number
AU1455500A
AU1455500A AU14555/00A AU1455500A AU1455500A AU 1455500 A AU1455500 A AU 1455500A AU 14555/00 A AU14555/00 A AU 14555/00A AU 1455500 A AU1455500 A AU 1455500A AU 1455500 A AU1455500 A AU 1455500A
Authority
AU
Australia
Prior art keywords
thiadiazole
oxadiazole
combinatorial libraries
triazole derivatives
triazole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU14555/00A
Other languages
English (en)
Inventor
Amy L. Hannah
R. Normand Hebert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Trega Biosciences Inc
Original Assignee
Trega Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trega Biosciences Inc filed Critical Trega Biosciences Inc
Publication of AU1455500A publication Critical patent/AU1455500A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/14—Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/11—Compounds covalently bound to a solid support

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Structural Engineering (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU14555/00A 1998-10-29 1999-10-28 Oxadiazole, thiadiazole and triazole derivatives and combinatorial libraries thereof Abandoned AU1455500A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18322298A 1998-10-29 1998-10-29
US09183222 1998-10-29
PCT/US1999/025331 WO2000025768A1 (fr) 1998-10-29 1999-10-28 Derives oxadiazole, thiadiazole et triazole et bibliotheques combinatoires contenant ces derives

Publications (1)

Publication Number Publication Date
AU1455500A true AU1455500A (en) 2000-05-22

Family

ID=22671958

Family Applications (1)

Application Number Title Priority Date Filing Date
AU14555/00A Abandoned AU1455500A (en) 1998-10-29 1999-10-28 Oxadiazole, thiadiazole and triazole derivatives and combinatorial libraries thereof

Country Status (3)

Country Link
EP (1) EP1126833A4 (fr)
AU (1) AU1455500A (fr)
WO (1) WO2000025768A1 (fr)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001002375A1 (fr) * 1999-07-01 2001-01-11 Chemrx Advanced Technologies, Inc. Synthese d'oxadiazoles
AU2001233044A1 (en) * 2000-01-28 2001-08-07 Akkadix Corporation Methods for killing nematodes and nematode eggs using bis-amino-1,2,4-thiadiazoles
US6683191B2 (en) 2000-06-05 2004-01-27 Ortho-Mcneil Pharmaceuticals, Inc. Method for synthesis of substituted azole libraries
US6951948B2 (en) 2000-06-05 2005-10-04 Ortho-Mcneil Pharmaceutical, Inc. Method for synthesis of substituted azole libraries
US6482829B2 (en) 2000-06-08 2002-11-19 Hoffmann-La Roche Inc. Substituted heterocyclic siprodecane compound active as an antagonist of neurokinin 1 receptor
US7390813B1 (en) 2001-12-21 2008-06-24 Xenon Pharmaceuticals Inc. Pyridylpiperazines and aminonicotinamides and their use as therapeutic agents
UA84420C2 (ru) 2003-04-11 2008-10-27 ПиТиСи ТЕРАПЬЮТИКС, ИНК. СОЕДИНЕНИЯ 1,2,4-ОКСАДИАЗОЛБЕНЗОЙНОЙ КИСЛОТЫ, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ (ВАРИАНТЫ) И ПРИМЕНЕНИЕ СОЕДИНЕНИЙ ДЛЯ ЛЕЧЕНИЯ ЗАБОЛЕВАНИЯ, СВЯЗАННОГО С ПРЕЖДЕВРЕМЕННОЙ ТЕРМИНАЦИЕЙ ТРАНСЛЯЦИИ ИЛИ НОНСЕНС-ОБУСЛОВЛЕННЫМ УМЕНЬШЕНИЕМ мРНК
WO2005011655A2 (fr) 2003-07-30 2005-02-10 Xenon Pharmaceuticals Inc. Derives de pyridazine et leur utilisation en tant qu'agents therapeutiques
GB0325956D0 (en) 2003-11-06 2003-12-10 Addex Pharmaceuticals Sa Novel compounds
EP1697333A4 (fr) 2003-12-17 2009-07-08 Merck & Co Inc Carboxylates propanoiques 3,4-disusbstitues utilises en tant qu'agonistes du recepteur s1p (edg)
US7453002B2 (en) 2004-06-15 2008-11-18 Bristol-Myers Squibb Company Five-membered heterocycles useful as serine protease inhibitors
JP4958786B2 (ja) 2004-09-20 2012-06-20 ゼノン・ファーマシューティカルズ・インコーポレイテッド 複素環誘導体および治療薬としてのそれらの使用
US7592343B2 (en) 2004-09-20 2009-09-22 Xenon Pharmaceuticals Inc. Pyridazine-piperazine compounds and their use as stearoyl-CoA desaturase inhibitors
WO2006034341A2 (fr) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Derives heterocycliques et leur utilisation en tant qu'agents therapeutiques
US8071603B2 (en) 2004-09-20 2011-12-06 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors
BRPI0515488A (pt) 2004-09-20 2008-07-29 Xenon Pharmaceuticals Inc derivados de heterocìclicos e seu uso como agentes terapêuticos
EP1799668A1 (fr) 2004-09-20 2007-06-27 Xenon Pharmaceuticals Inc. Derives heterocycliques et leur utilisation en tant que modulateurs de stearoyle-coa desaturase
GB0508319D0 (en) 2005-04-25 2005-06-01 Novartis Ag Organic compounds
BRPI0611187A2 (pt) 2005-06-03 2010-08-24 Xenon Pharmaceuticals Inc derivados aminotiazàis como inibidores da estearoil-coa desaturase humana
JP5367563B2 (ja) 2006-03-30 2013-12-11 ピーティーシー セラピューティクス，インコーポレーテッド ナンセンス突然変異を有するｄｎａからの機能的タンパク質の産生のための方法及びそれと関連した障害の治療
US9090604B2 (en) 2006-07-27 2015-07-28 E I Du Pont De Nemours And Company Fungicidal azocyclic amides
WO2008013622A2 (fr) 2006-07-27 2008-01-31 E. I. Du Pont De Nemours And Company Amides azocycliques fongicides
US8314138B2 (en) 2006-08-24 2012-11-20 Novartis Ag Pyrazole derivative as SCD1 inhibitors for the treatment of diabetes
BRPI0720043A2 (pt) 2006-12-15 2014-01-07 Abbott Lab Composto oxadiazol
US8969342B2 (en) 2009-03-20 2015-03-03 Brandeis University Compounds and methods for treating mammalian gastrointestinal microbial infections
AR081331A1 (es) 2010-04-23 2012-08-08 Cytokinetics Inc Amino- pirimidinas composiciones de las mismas y metodos para el uso de los mismos
WO2011133920A1 (fr) 2010-04-23 2011-10-27 Cytokinetics, Inc. Aminopyridines et aminotriazines, leurs compositions et leurs procédés d'utilisation
AR081626A1 (es) 2010-04-23 2012-10-10 Cytokinetics Inc Compuestos amino-piridazinicos, composiciones farmaceuticas que los contienen y uso de los mismos para tratar trastornos musculares cardiacos y esqueleticos
US8759380B2 (en) 2011-04-22 2014-06-24 Cytokinetics, Inc. Certain heterocycles, compositions thereof, and methods for their use
WO2014028931A2 (fr) 2012-08-17 2014-02-20 Brandeis University Composés et procédés de traitement d'infections microbiennes gastro-intestinales de mammifère
CA3174516A1 (fr) 2014-03-06 2015-09-11 Ptc Therapeutics, Inc. Compositions pharmaceutiques et sels d'un acide benzoique 1,2,4-oxadiazole
WO2017075312A1 (fr) 2015-10-30 2017-05-04 Ptc Therapeutics, Inc. Méthodes de traitement de l'épilepsie
CN112010828B (zh) * 2020-09-27 2023-01-31 中国医科大学 Cdk7小分子抑制剂的化合物及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8801289D0 (en) * 1988-01-21 1988-02-17 Shell Int Research Oxadiazole compounds their preparation & their use as pesticides
US5242890A (en) * 1988-07-07 1993-09-07 Korea Research Institute Of Chemical Technology 1,2,4-oxadiazole derivative, useful as selective herbicide
US5366987A (en) * 1991-08-22 1994-11-22 Warner-Lambert Company Isoxazolyl-substituted alkyl amide ACAT inhibitors
MX9705710A (es) * 1995-01-27 1997-10-31 Novo Nordisk As Compuestos con propiedades de liberacion de la hormona del crecimiento.
JP2002534955A (ja) * 1995-10-18 2002-10-15 メルク エンド カンパニー インコーポレーテッド シクロペンチルタキキニン受容体アンタゴニスト
JP2000500742A (ja) * 1995-10-30 2000-01-25 スミスクライン・ビーチャム・コーポレイション プロテアーゼ阻害剤
AU6320998A (en) * 1997-02-21 1998-09-09 Bristol-Myers Squibb Company Benzoic acid derivatives and related compounds as antiarrhythmic agents

Also Published As

Publication number Publication date
EP1126833A4 (fr) 2004-09-08
EP1126833A2 (fr) 2001-08-29
WO2000025768A8 (fr) 2000-08-24
WO2000025768A1 (fr) 2000-05-11

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase