AU1039400A - Opioid analgesic - Google Patents

Opioid analgesic

Info

Publication number
AU1039400A
AU1039400A AU10394/00A AU1039400A AU1039400A AU 1039400 A AU1039400 A AU 1039400A AU 10394/00 A AU10394/00 A AU 10394/00A AU 1039400 A AU1039400 A AU 1039400A AU 1039400 A AU1039400 A AU 1039400A
Authority
AU
Australia
Prior art keywords
active substance
opioid analgesic
weight
release rate
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU10394/00A
Inventor
Bianca Brogmann
Udo Hahn
Christof Spitzley
Walter Wimmer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Euro Celtique SA
Original Assignee
Euro Celtique SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Celtique SA filed Critical Euro Celtique SA
Publication of AU1039400A publication Critical patent/AU1039400A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention relates to a pharmaceutical preparation, especially for oral administration, having at least one active substance and formulation components influencing the release of the active substance. Said preparation comprises at least one opioid analgesic as active substance, which is formulated proportionally for rapid and retarded release in such a way that the in vitro release rate from the preparation according to the Ph. Eur. Paddle Method showed a mean value of more than 40 % by weight after one hour, wherein the average value of the in vitro release rate after four hours was still less than 80 % by weight of the active substance.
AU10394/00A 1998-10-15 1999-10-15 Opioid analgesic Abandoned AU1039400A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE29818454U DE29818454U1 (en) 1998-10-15 1998-10-15 Opioid analgesic
DE29818454 1998-10-15
PCT/EP1999/007842 WO2000021520A2 (en) 1998-10-15 1999-10-15 Opioid analgesic

Publications (1)

Publication Number Publication Date
AU1039400A true AU1039400A (en) 2000-05-01

Family

ID=8063985

Family Applications (1)

Application Number Title Priority Date Filing Date
AU10394/00A Abandoned AU1039400A (en) 1998-10-15 1999-10-15 Opioid analgesic

Country Status (10)

Country Link
EP (1) EP1121109B8 (en)
JP (1) JP5414956B2 (en)
AT (1) ATE327742T1 (en)
AU (1) AU1039400A (en)
CY (1) CY1105168T1 (en)
DE (2) DE29818454U1 (en)
DK (1) DK1121109T3 (en)
ES (1) ES2267301T3 (en)
PT (1) PT1121109E (en)
WO (1) WO2000021520A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030130297A1 (en) 2001-07-06 2003-07-10 Endo Pharmaceuticals, Inc. Oral administration of 6-hydroxy-oxymorphone for use as an analgesic
US8329216B2 (en) 2001-07-06 2012-12-11 Endo Pharmaceuticals Inc. Oxymorphone controlled release formulations
EP1404332A1 (en) * 2001-07-06 2004-04-07 Penwest Pharmaceuticals Company Methods of making sustained release formulations of oxymorphone related applications
PT2425821T (en) 2002-04-05 2017-08-23 Mundipharma Farmacêutica Lda Pharmaceutical preparation containing oxycodone and naloxone
JP2006328053A (en) * 2005-04-26 2006-12-07 Takeda Chem Ind Ltd Morphine-containing medicine
PL2002828T3 (en) 2006-03-30 2019-11-29 Nippon Zoki Pharmaceutical Co Solid pharmaceutical preparation
US9226907B2 (en) 2008-02-01 2016-01-05 Abbvie Inc. Extended release hydrocodone acetaminophen and related methods and uses thereof
JP5905872B2 (en) * 2010-04-07 2016-04-20 ルピン・リミテッド Controlled release pharmaceutical composition of tapentadol

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL109460A (en) * 1993-05-10 1998-03-10 Euro Celtique Sa Controlled release formulation comprising tramadol
IL110014A (en) * 1993-07-01 1999-11-30 Euro Celtique Sa Solid controlled-release oral dosage forms of opioid analgesics
DE4329794C2 (en) * 1993-09-03 1997-09-18 Gruenenthal Gmbh Tramadol salt-containing drugs with delayed release
US5395626A (en) * 1994-03-23 1995-03-07 Ortho Pharmaceutical Corporation Multilayered controlled release pharmaceutical dosage form
US5645858A (en) * 1994-10-06 1997-07-08 Ortho Pharmaceutical Corporation Multilayered controlled release pharmaceutical dosage form
KR100341829B1 (en) * 1996-03-08 2002-08-22 니코메드 덴마크 에이/에스 Modified release multiple-units dosage composition
DE19710008A1 (en) * 1997-03-12 1998-09-17 Basf Ag Solid, at least two-phase formulations of a sustained-release opioid analgesic

Also Published As

Publication number Publication date
DE29818454U1 (en) 1999-01-14
EP1121109A2 (en) 2001-08-08
PT1121109E (en) 2006-09-29
ES2267301T3 (en) 2007-03-01
ATE327742T1 (en) 2006-06-15
CY1105168T1 (en) 2010-03-03
DE59913493D1 (en) 2006-07-06
EP1121109B1 (en) 2006-05-31
JP2002527384A (en) 2002-08-27
WO2000021520A3 (en) 2000-08-03
JP5414956B2 (en) 2014-02-12
WO2000021520A2 (en) 2000-04-20
DK1121109T3 (en) 2006-10-02
EP1121109B8 (en) 2006-07-19

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase