YU20050410A - Controlled release oxycodone compositions - Google Patents
Controlled release oxycodone compositionsInfo
- Publication number
- YU20050410A YU20050410A YU20050410A YUP20050410A YU20050410A YU 20050410 A YU20050410 A YU 20050410A YU 20050410 A YU20050410 A YU 20050410A YU P20050410 A YUP20050410 A YU P20050410A YU 20050410 A YU20050410 A YU 20050410A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- oxycodone
- weight
- dosage form
- hours
- controlled release
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5015—Organic compounds, e.g. fats, sugars
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Emergency Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Invention herewith refers to a controlled release of a solid dosage form for oral administration, that contains an analgetic efficient quantity of oxycodone or oxycodone salts in one matrix, where the speed of the mentioned dosage form has an in vitro dissolution rate when measured by the USP Paddle Method at 100 -1 in 900 ml aqueous buffer (pH between 1.6 and 7.2) at 37 °C, between 12.5 % and 42.5 % (by weight) oxycodone salt released after 1 hour, between 25 % and 55 % (by weight) oxycodone salt released after 2 hours, between 45 % and 75 % (by weight) oxycodone salt released after 4 hours and between 55 % and 85 % (by weight) oxycodone salt released after 6 hours, where in vitro dissolution rate is independent of pH, when pH is between 1.6 and 7.2. That dosage form is achieved in the form of a pill. Invention relates to the procedure for preparation of the same oral dosage form.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21014692A | 1992-11-25 | 1992-11-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
YU20050410A true YU20050410A (en) | 2006-05-25 |
Family
ID=47559778
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU20050409A YU20050409A (en) | 1992-11-25 | 1993-05-21 | Controlled release oxycodone compositions |
YU20050408A YU20050408A (en) | 1992-11-25 | 1993-05-21 | Controlled release oxycodone compositions |
YU20050410A YU20050410A (en) | 1992-11-25 | 1993-05-21 | Controlled release oxycodone compositions |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU20050409A YU20050409A (en) | 1992-11-25 | 1993-05-21 | Controlled release oxycodone compositions |
YU20050408A YU20050408A (en) | 1992-11-25 | 1993-05-21 | Controlled release oxycodone compositions |
Country Status (2)
Country | Link |
---|---|
RS (1) | RS50053B (en) |
YU (3) | YU20050409A (en) |
-
1993
- 1993-05-21 RS YUP-708/04A patent/RS50053B/en unknown
- 1993-05-21 YU YU20050409A patent/YU20050409A/en unknown
- 1993-05-21 YU YU20050408A patent/YU20050408A/en unknown
- 1993-05-21 YU YU20050410A patent/YU20050410A/en unknown
Also Published As
Publication number | Publication date |
---|---|
YU20050409A (en) | 2006-05-25 |
YU20050408A (en) | 2006-05-25 |
YU70804A (en) | 2005-11-28 |
RS50053B (en) | 2008-11-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP0249347A3 (en) | Controlled release dihydrocodeine composition | |
YU35893A (en) | CONTROLLED-RELEASE OXIDON FORMULATIONS AND THEIR USE | |
GB2196848B (en) | Controlled release hydromorphone composition | |
EP0149920A3 (en) | Pharmaceutical formulation | |
RU2005115855A (en) | COMPOSITION OF TRAMADOL PROLONGED BY RELEASE WITH 24 HOUR ACTION | |
EP1243269A3 (en) | Opioid formulations having extended controlled release | |
AR042472A1 (en) | CONTROLLED RELEASE PREPARATIONS THAT INCLUDE TRAMADOL AND TOPIRAMATO | |
MY129946A (en) | Compound with gastric acid inhibitory effect and process for its preparation. | |
AU3071300A (en) | Multiparticulate bisoprolol formulation | |
YU20050410A (en) | Controlled release oxycodone compositions | |
AU1039400A (en) | Opioid analgesic | |
YU20050413A (en) | Controlled release oxycodone compositions |