ATE964T1 - Retinsaeure- und 7,8-dehyd ro-retinsaeure-n-(carboxy)-phenyl-amide, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel. - Google Patents
Retinsaeure- und 7,8-dehyd ro-retinsaeure-n-(carboxy)-phenyl-amide, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel.Info
- Publication number
- ATE964T1 ATE964T1 AT79103684T AT79103684T ATE964T1 AT E964 T1 ATE964 T1 AT E964T1 AT 79103684 T AT79103684 T AT 79103684T AT 79103684 T AT79103684 T AT 79103684T AT E964 T1 ATE964 T1 AT E964T1
- Authority
- AT
- Austria
- Prior art keywords
- acid
- carboxy
- dehydro
- retinic
- preparation
- Prior art date
Links
- SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 title 1
- 239000008177 pharmaceutical agent Substances 0.000 title 1
- 229930002330 retinoic acid Natural products 0.000 title 1
- 229960001727 tretinoin Drugs 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 10
- PWXJULSLLONQHY-UHFFFAOYSA-N phenylcarbamic acid Chemical class OC(=O)NC1=CC=CC=C1 PWXJULSLLONQHY-UHFFFAOYSA-N 0.000 abstract 4
- ALYNCZNDIQEVRV-UHFFFAOYSA-N 4-aminobenzoic acid Chemical class NC1=CC=C(C(O)=O)C=C1 ALYNCZNDIQEVRV-UHFFFAOYSA-N 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- XFDUHJPVQKIXHO-UHFFFAOYSA-N 3-aminobenzoic acid Chemical class NC1=CC=CC(C(O)=O)=C1 XFDUHJPVQKIXHO-UHFFFAOYSA-N 0.000 abstract 1
- 229960004050 aminobenzoic acid Drugs 0.000 abstract 1
- RWZYAGGXGHYGMB-UHFFFAOYSA-N anthranilic acid Chemical class NC1=CC=CC=C1C(O)=O RWZYAGGXGHYGMB-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/09—Geometrical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19782843811 DE2843811A1 (de) | 1978-10-07 | 1978-10-07 | Retinsaeure- und 7,8-dehydro-retinsaeure-n-(carboxy)-phenylamide |
| EP79103684A EP0009777B1 (de) | 1978-10-07 | 1979-09-28 | Retinsäure- und 7,8-Dehydro-retinsäure-N-(carboxy)-phenyl-amide, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Mittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE964T1 true ATE964T1 (de) | 1982-05-15 |
Family
ID=6051651
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT79103684T ATE964T1 (de) | 1978-10-07 | 1979-09-28 | Retinsaeure- und 7,8-dehyd ro-retinsaeure-n-(carboxy)-phenyl-amide, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel. |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0009777B1 (de) |
| JP (1) | JPS5551058A (de) |
| AT (1) | ATE964T1 (de) |
| CA (1) | CA1127170A (de) |
| DE (2) | DE2843811A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3002545A1 (de) * | 1980-01-25 | 1981-07-30 | Basf Ag, 6700 Ludwigshafen | 5-amino-tetrazol-derivate von retinsaeuren, ihre herstellung und diese enthaltende pharmazeutische zubereitungen |
| JP2589295B2 (ja) * | 1986-11-14 | 1997-03-12 | キヤノン株式会社 | 画像形成装置 |
| JP3431706B2 (ja) * | 1994-12-16 | 2003-07-28 | 新日本石油化学株式会社 | 積層体・不織布または織布並びにそれらを用いた強化積層体 |
| US6054086A (en) * | 1995-03-24 | 2000-04-25 | Nippon Petrochemicals Co., Ltd. | Process of making high-strength yarns |
| US5716982A (en) * | 1995-06-07 | 1998-02-10 | Institute Of Materia Medica, An Institute Of The Chinese Academy Of Medical Sciences | Retinoids and methods of use of same |
| US5703130A (en) * | 1995-06-07 | 1997-12-30 | Institute Of Materia Medica, An Institute Of The Chinese Academy Of Medical Sciences | Chalcone retinoids and methods of use of same |
| US5968940A (en) * | 1995-06-08 | 1999-10-19 | Institute Of Materia Medica | Retinoids and methods of use of same |
| CN102260186B (zh) * | 2011-05-09 | 2014-03-12 | 北京吉科特科技有限责任公司 | 4-羧基苯基视黄酰胺基乙醇合物及其制备方法和药物组合物 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2300107C2 (de) * | 1973-01-03 | 1982-03-11 | Basf Ag, 6700 Ludwigshafen | Vitamin A-Säureanilid-4-carbonsäureäthylester, Verfahren zu seiner Herstellung und diesen enthaltende Zubereitungen |
| DE2456959A1 (de) * | 1974-12-03 | 1976-06-16 | Basf Ag | 4-(e)- und 4-(z)-7-methyl-9-(2,6,6trimethyl-1-cyclohexen-1-yl)-nona-2,4,6,8tetraencarbonsaeure, ihre derivate und diese enthaltende zubereitungen |
-
1978
- 1978-10-07 DE DE19782843811 patent/DE2843811A1/de active Pending
-
1979
- 1979-09-28 DE DE7979103684T patent/DE2962720D1/de not_active Expired
- 1979-09-28 CA CA336,670A patent/CA1127170A/en not_active Expired
- 1979-09-28 AT AT79103684T patent/ATE964T1/de not_active IP Right Cessation
- 1979-09-28 EP EP79103684A patent/EP0009777B1/de not_active Expired
- 1979-10-05 JP JP12811279A patent/JPS5551058A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0009777A1 (de) | 1980-04-16 |
| DE2962720D1 (en) | 1982-06-24 |
| EP0009777B1 (de) | 1982-05-05 |
| CA1127170A (en) | 1982-07-06 |
| JPS5551058A (en) | 1980-04-14 |
| DE2843811A1 (de) | 1980-04-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REN | Ceased due to non-payment of the annual fee |