ATE964T1 - RETINOIC ACID AND 7,8-DEHYDRO-RETINIC ACID-N-(CARBOXY)-PHENYL AMIDES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL AGENTS CONTAINING THEM. - Google Patents
RETINOIC ACID AND 7,8-DEHYDRO-RETINIC ACID-N-(CARBOXY)-PHENYL AMIDES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL AGENTS CONTAINING THEM.Info
- Publication number
- ATE964T1 ATE964T1 AT79103684T AT79103684T ATE964T1 AT E964 T1 ATE964 T1 AT E964T1 AT 79103684 T AT79103684 T AT 79103684T AT 79103684 T AT79103684 T AT 79103684T AT E964 T1 ATE964 T1 AT E964T1
- Authority
- AT
- Austria
- Prior art keywords
- acid
- carboxy
- dehydro
- retinic
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/09—Geometrical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
For the Contracting States : BE, CH, DE, FR, GB, IT, LU, NL, SE 1. Retinic acid N-(carboxy)-phenylamides and 7,8-dehydro-retinic acid N-(carboxy)-phenylamides of the formulae I and II see diagramm : EP0009777,P5,F1 where the broken line is a chemical bond or two hydrogen atoms, and the carboxyl group in the aromatic ring is in the ortho-, meta- or para-position. For the Contracting State : AT 1. A process for the preparation of retinic acid N-(carboxy)-phenylamides and 7,8-dehydro-retinic acid N-(carboxy)-phenylamides of the formulae I and II see diagramm : EP0009777,P6,F1 where the broken line is a chemical bond or two hydrogen atoms, and the carboxyl group in the aromatic ring is in the ortho-, meta- or para-position, characterized in that a functional acid derivative of all-E- of or 13-Z-retinic acid or all-E- or 13-Z-7,8-dehydro-retinic acid is reacted with o-, m- or p-aminobenzoic acid or an acid derivative thereof in the conventional manner, and, where appropriate, the resulting acid derivative is hydrolyzed to the acid in the conventional manner.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19782843811 DE2843811A1 (en) | 1978-10-07 | 1978-10-07 | RETINIC ACID AND 7,8-DEHYDRO RETINIC ACID-N- (CARBOXY) -PHENYLAMIDE |
EP79103684A EP0009777B1 (en) | 1978-10-07 | 1979-09-28 | Retinoic- and 7,8-dehydro-retinoic-acid-n-(carboxy)phenyl amides, process for their preparation and pharmaceutical compositions containing them |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE964T1 true ATE964T1 (en) | 1982-05-15 |
Family
ID=6051651
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT79103684T ATE964T1 (en) | 1978-10-07 | 1979-09-28 | RETINOIC ACID AND 7,8-DEHYDRO-RETINIC ACID-N-(CARBOXY)-PHENYL AMIDES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL AGENTS CONTAINING THEM. |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0009777B1 (en) |
JP (1) | JPS5551058A (en) |
AT (1) | ATE964T1 (en) |
CA (1) | CA1127170A (en) |
DE (2) | DE2843811A1 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3002545A1 (en) * | 1980-01-25 | 1981-07-30 | Basf Ag, 6700 Ludwigshafen | 5-AMINO-TETRAZOLE DERIVATIVES OF RETINIC ACIDS, THEIR PRODUCTION AND THE PHARMACEUTICAL PREPARATIONS CONTAINING THEM |
JP2589295B2 (en) * | 1986-11-14 | 1997-03-12 | キヤノン株式会社 | Image forming device |
JP3431706B2 (en) * | 1994-12-16 | 2003-07-28 | 新日本石油化学株式会社 | Laminate, nonwoven fabric or woven fabric and reinforced laminate using them |
US6054086A (en) * | 1995-03-24 | 2000-04-25 | Nippon Petrochemicals Co., Ltd. | Process of making high-strength yarns |
US5716982A (en) * | 1995-06-07 | 1998-02-10 | Institute Of Materia Medica, An Institute Of The Chinese Academy Of Medical Sciences | Retinoids and methods of use of same |
US5703130A (en) * | 1995-06-07 | 1997-12-30 | Institute Of Materia Medica, An Institute Of The Chinese Academy Of Medical Sciences | Chalcone retinoids and methods of use of same |
US5968940A (en) * | 1995-06-08 | 1999-10-19 | Institute Of Materia Medica | Retinoids and methods of use of same |
CN102260186B (en) * | 2011-05-09 | 2014-03-12 | 北京吉科特科技有限责任公司 | N-(4-carboxyl phenyl)retinamide ethanol compound and preparation method thereof, and medicinal composition |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2300107C2 (en) * | 1973-01-03 | 1982-03-11 | Basf Ag, 6700 Ludwigshafen | Vitamin A acid anilide-4-carboxylic acid ethyl ester, process for its production and preparations containing it |
DE2456959A1 (en) * | 1974-12-03 | 1976-06-16 | Basf Ag | 4- (E) - AND 4- (Z) -7-METHYL-9- (2,6,6TRIMETHYL-1-CYCLOHEXEN-1-YL) -NONA-2,4,6,8TETRAEN CARBONIC ACID, ITS DERIVATIVES AND CONTAINING THEM PREPARATIONS |
-
1978
- 1978-10-07 DE DE19782843811 patent/DE2843811A1/en active Pending
-
1979
- 1979-09-28 CA CA336,670A patent/CA1127170A/en not_active Expired
- 1979-09-28 DE DE7979103684T patent/DE2962720D1/en not_active Expired
- 1979-09-28 EP EP79103684A patent/EP0009777B1/en not_active Expired
- 1979-09-28 AT AT79103684T patent/ATE964T1/en not_active IP Right Cessation
- 1979-10-05 JP JP12811279A patent/JPS5551058A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
CA1127170A (en) | 1982-07-06 |
DE2843811A1 (en) | 1980-04-24 |
DE2962720D1 (en) | 1982-06-24 |
EP0009777A1 (en) | 1980-04-16 |
JPS5551058A (en) | 1980-04-14 |
EP0009777B1 (en) | 1982-05-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
REN | Ceased due to non-payment of the annual fee |