FR2351652A1 - (p)-Chlorophenoxy-isobutyryl-glycinamide - for use as lipid metaboliser - Google Patents

(p)-Chlorophenoxy-isobutyryl-glycinamide - for use as lipid metaboliser

Info

Publication number
FR2351652A1
FR2351652A1 FR7615343A FR7615343A FR2351652A1 FR 2351652 A1 FR2351652 A1 FR 2351652A1 FR 7615343 A FR7615343 A FR 7615343A FR 7615343 A FR7615343 A FR 7615343A FR 2351652 A1 FR2351652 A1 FR 2351652A1
Authority
FR
France
Prior art keywords
glycinamide
cpd
metaboliser
chlorophenoxy
isobutyryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7615343A
Other languages
French (fr)
Other versions
FR2351652B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kotobuki Seiyaku Co Ltd
Original Assignee
Kotobuki Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kotobuki Seiyaku Co Ltd filed Critical Kotobuki Seiyaku Co Ltd
Priority to FR7615343A priority Critical patent/FR2351652A1/en
Publication of FR2351652A1 publication Critical patent/FR2351652A1/en
Application granted granted Critical
Publication of FR2351652B1 publication Critical patent/FR2351652B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

p-Chlorophenoxyisobutyryl-glycinamide, of formula (I), is a new cpd. Cpd. (I) promotes lipid metabolism. It gives greater reductions in serum cholestrol levels, is slightly less toxic and is more rapidly absorbed than ethyl p-chlorophenoxyisobutyrate (II). Unlike (II), it is tasteless and odourless and can be administered in solid form. Cpd. (I) can be prepd. by reacting a glycine deriv. of formula R1NHCH2COR2 (where R1 is H or a reactive gp.; R2 is NH2 or lower alkyl) with p-chlorophenoxyisobutyric acid (III) or a reactive deriv. of (III). When R2 = alkyl, the product is reacted with NH3.
FR7615343A 1976-05-21 1976-05-21 (p)-Chlorophenoxy-isobutyryl-glycinamide - for use as lipid metaboliser Granted FR2351652A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7615343A FR2351652A1 (en) 1976-05-21 1976-05-21 (p)-Chlorophenoxy-isobutyryl-glycinamide - for use as lipid metaboliser

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7615343A FR2351652A1 (en) 1976-05-21 1976-05-21 (p)-Chlorophenoxy-isobutyryl-glycinamide - for use as lipid metaboliser

Publications (2)

Publication Number Publication Date
FR2351652A1 true FR2351652A1 (en) 1977-12-16
FR2351652B1 FR2351652B1 (en) 1978-11-10

Family

ID=9173453

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7615343A Granted FR2351652A1 (en) 1976-05-21 1976-05-21 (p)-Chlorophenoxy-isobutyryl-glycinamide - for use as lipid metaboliser

Country Status (1)

Country Link
FR (1) FR2351652A1 (en)

Also Published As

Publication number Publication date
FR2351652B1 (en) 1978-11-10

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Legal Events

Date Code Title Description
ST Notification of lapse