ATE92498T1 - Primycinkomponenten und verfahren zur trennung des antibiotischen komplexes. - Google Patents

Primycinkomponenten und verfahren zur trennung des antibiotischen komplexes.

Info

Publication number
ATE92498T1
ATE92498T1 AT85902625T AT85902625T ATE92498T1 AT E92498 T1 ATE92498 T1 AT E92498T1 AT 85902625 T AT85902625 T AT 85902625T AT 85902625 T AT85902625 T AT 85902625T AT E92498 T1 ATE92498 T1 AT E92498T1
Authority
AT
Austria
Prior art keywords
separation
methods
antibiotic complex
pct
primycin components
Prior art date
Application number
AT85902625T
Other languages
English (en)
Inventor
Imre Szilagyi
Gyula Dekany
Judit Frank
Gabor Horvath
Gabor Kulcsar
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU212584A external-priority patent/HU195514B/hu
Priority claimed from HU842869A external-priority patent/HU196425B/hu
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Application granted granted Critical
Publication of ATE92498T1 publication Critical patent/ATE92498T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT85902625T 1984-05-31 1985-05-31 Primycinkomponenten und verfahren zur trennung des antibiotischen komplexes. ATE92498T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
HU212584A HU195514B (en) 1984-05-31 1984-05-31 Process for the digestion of triamycine, an antibioticcomplex
HU842869A HU196425B (en) 1984-07-26 1984-07-26 Process for producing components of primicin and pharmaceutical compositions containing them
PCT/HU1985/000034 WO1985005621A1 (en) 1984-05-31 1985-05-31 Primysin components and process for the separation of the antibiotic complex
EP85902625A EP0182851B1 (de) 1984-05-31 1985-05-31 Primycinkomponenten und verfahren zur trennung des antibiotischen komplexes

Publications (1)

Publication Number Publication Date
ATE92498T1 true ATE92498T1 (de) 1993-08-15

Family

ID=26317473

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85902625T ATE92498T1 (de) 1984-05-31 1985-05-31 Primycinkomponenten und verfahren zur trennung des antibiotischen komplexes.

Country Status (10)

Country Link
US (2) US4873348A (de)
EP (1) EP0182851B1 (de)
KR (1) KR930000164B1 (de)
AT (1) ATE92498T1 (de)
CA (1) CA1274508A (de)
DE (1) DE3587499T2 (de)
DK (1) DK46086D0 (de)
FI (1) FI80046C (de)
IL (1) IL75357A (de)
WO (1) WO1985005621A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU202248B (en) * 1988-06-14 1991-02-28 Chinoin Gyogyszer Es Vegyeszet Process for producing pseudo-primicin, it's components and pharmaceutical compositions containing them as active components
HU205366B (en) * 1988-11-18 1992-04-28 Chinoin Gyogyszer Es Vegyeszet Process for producing water-soluble primycin complexes and pharmaceutical compositions comprising such active ingredient
HU207222B (en) * 1990-02-15 1993-03-29 Chinoin Gyogyszer Es Vegyeszet Process for producing eyedrops containing primycin
US20030091540A1 (en) * 2001-10-16 2003-05-15 Nawaz Ahmad Compositions and methods for delivering antibacterial, antifungal and antiviral ointments to the oral, nasal or vaginal cavity
US8026407B2 (en) * 2006-08-01 2011-09-27 3M Innovative Properties Company Antimicrobial compression bandage
US8609733B2 (en) 2008-05-19 2013-12-17 Massachusetts Institute Of Technology Sensory-specific local anesthesia and prolonged duration local anesthesia
US8952152B2 (en) 2009-03-24 2015-02-10 Proteus S.A. Methods for purifying phycotoxins, pharmaceutical compositions containing purified phycotoxins, and methods of use thereof
HU229804B1 (en) 2009-10-29 2014-07-28 Pannonpharma Gyogyszergyarto Kft Method of production of primycin, primycin components, and/or precursors and metabolites of primycin via fementation by the use of bacterial species saccharomonospora azurea
HU230455B1 (hu) 2011-10-25 2016-07-28 Pannonpharma Gyógyszergyártó Zrt. Primycin vagy primycin komponensek vagy ezek kombinációi mint speciális kórokozócsoportok által okozott fertőzések kezelésére vagy megelőzésére alkalmas gyógyszerhatóanyagok
KR20240042210A (ko) 2013-03-15 2024-04-01 더 칠드런스 메디칼 센터 코포레이션 지속성 국소 마취용 네오삭시톡신 조합 제형

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT268522B (de) * 1965-10-20 1969-02-10 Chinoin Gyogyszer Es Vegyeszet Verfahren zur Herstellung von Primycin
US4070376A (en) * 1974-02-04 1978-01-24 Hoffmann-La Roche, Inc. Antibiotic 1745A/X and methods for the production thereof

Also Published As

Publication number Publication date
FI860426A0 (fi) 1986-01-29
US4873348A (en) 1989-10-10
DE3587499T2 (de) 1993-11-25
DE3587499D1 (de) 1993-09-09
EP0182851B1 (de) 1993-08-04
FI80046C (fi) 1990-04-10
US5093359A (en) 1992-03-03
CA1274508A (en) 1990-09-25
IL75357A0 (en) 1985-09-29
KR860700121A (ko) 1986-03-31
EP0182851A1 (de) 1986-06-04
FI860426A (fi) 1986-01-29
KR930000164B1 (ko) 1993-01-11
DK46086A (da) 1986-01-30
FI80046B (fi) 1989-12-29
IL75357A (en) 1992-05-25
WO1985005621A1 (en) 1985-12-19
DK46086D0 (da) 1986-01-30

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