ATE92320T1 - Kombinationspraeparate enthaltend rifampicin und thioacetazon sowie gegebenenfalls isonicotinsaeurehydrazid oder ethambutol als aktive wirkstoffe. - Google Patents
Kombinationspraeparate enthaltend rifampicin und thioacetazon sowie gegebenenfalls isonicotinsaeurehydrazid oder ethambutol als aktive wirkstoffe.Info
- Publication number
- ATE92320T1 ATE92320T1 AT90108858T AT90108858T ATE92320T1 AT E92320 T1 ATE92320 T1 AT E92320T1 AT 90108858 T AT90108858 T AT 90108858T AT 90108858 T AT90108858 T AT 90108858T AT E92320 T1 ATE92320 T1 AT E92320T1
- Authority
- AT
- Austria
- Prior art keywords
- thioacetazone
- ethambutol
- applicable
- active substances
- acid hydrazide
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 2
- AEUTYOVWOVBAKS-UWVGGRQHSA-N ethambutol Chemical compound CC[C@@H](CO)NCCN[C@@H](CC)CO AEUTYOVWOVBAKS-UWVGGRQHSA-N 0.000 title 2
- UEIZUEWXLJOVLD-UHFFFAOYSA-N 3-(1-methylpyrrolidin-3-yl)pyridine Chemical compound C1N(C)CCC1C1=CC=CN=C1 UEIZUEWXLJOVLD-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- 239000013543 active substance Substances 0.000 title 1
- 229960000285 ethambutol Drugs 0.000 title 1
- JQXXHWHPUNPDRT-WLSIYKJHSA-N rifampicin Chemical compound O([C@](C1=O)(C)O/C=C/[C@@H]([C@H]([C@@H](OC(C)=O)[C@H](C)[C@H](O)[C@H](C)[C@@H](O)[C@@H](C)\C=C\C=C(C)/C(=O)NC=2C(O)=C3C([O-])=C4C)C)OC)C4=C1C3=C(O)C=2\C=N\N1CC[NH+](C)CC1 JQXXHWHPUNPDRT-WLSIYKJHSA-N 0.000 title 1
- 229960001225 rifampicin Drugs 0.000 title 1
- SRVJKTDHMYAMHA-WUXMJOGZSA-N thioacetazone Chemical compound CC(=O)NC1=CC=C(\C=N\NC(N)=S)C=C1 SRVJKTDHMYAMHA-WUXMJOGZSA-N 0.000 title 1
- 229960003231 thioacetazone Drugs 0.000 title 1
- 208000027531 mycobacterial infectious disease Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pyridine Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3916417A DE3916417A1 (de) | 1989-05-19 | 1989-05-19 | Kombinationspraeparate enthaltend rifampicin und thioacetazon sowie gegebenenfalls isonicotinsaeurehydrazid als aktive wirkstoffe |
| EP90108858A EP0398165B1 (de) | 1989-05-19 | 1990-05-11 | Kombinationspräparate enthaltend Rifampicin und Thioacetazon sowie gegebenenfalls Isonicotinsäurehydrazid oder Ethambutol als aktive Wirkstoffe |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE92320T1 true ATE92320T1 (de) | 1993-08-15 |
Family
ID=6381016
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90108858T ATE92320T1 (de) | 1989-05-19 | 1990-05-11 | Kombinationspraeparate enthaltend rifampicin und thioacetazon sowie gegebenenfalls isonicotinsaeurehydrazid oder ethambutol als aktive wirkstoffe. |
Country Status (4)
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002087547A1 (en) * | 2001-04-27 | 2002-11-07 | Lupin Limited | An improved process for preparation of four-drug anti-tubercular fixed dose combination |
| RU2195937C1 (ru) * | 2002-02-06 | 2003-01-10 | НИИ молекулярной медицины ММА им. И.М.Сеченова | Комбинированный противотуберкулезный препарат (ризобутол) |
| CN101404986B (zh) * | 2002-05-17 | 2011-09-28 | 赛奎拉公司 | 用于诊断和治疗感染性疾病的组合物和制药方法 |
| US7456222B2 (en) * | 2002-05-17 | 2008-11-25 | Sequella, Inc. | Anti tubercular drug: compositions and methods |
| US20040033986A1 (en) * | 2002-05-17 | 2004-02-19 | Protopopova Marina Nikolaevna | Anti tubercular drug: compositions and methods |
| US7884097B2 (en) * | 2003-09-05 | 2011-02-08 | Sequella, Inc. | Methods and compositions comprising diamines as new anti-tubercular therapeutics |
| US20050249804A1 (en) * | 2004-05-07 | 2005-11-10 | Sapte Vinay R | Stabilized short-course chemotherapy (SCC) anti-tuberculosis drug compositions |
| WO2009136965A1 (en) * | 2008-05-06 | 2009-11-12 | Sequella, Inc. | Compositions and methods comprising capuramycin analogues |
| RU2496475C2 (ru) | 2011-10-26 | 2013-10-27 | Александр Васильевич Иващенко | Фармацевтическая композиция и набор для лечения бактериальных инфекций |
| RU2627611C2 (ru) * | 2015-10-30 | 2017-08-09 | Акционерное общество "Фармасинтез" (АО "Фармасинтез") | Противотуберкулезная фармацевтическая композиция, содержащая тиоацетазон |
| WO2018035183A1 (en) * | 2016-08-16 | 2018-02-22 | University Of Rochester | Pharmaceutical composition containing polymyxin b/trimethoprim based therapeutics |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3751567A (en) * | 1969-03-24 | 1973-08-07 | Ciba Geigy Corp | Synergistic antibiotics |
-
1989
- 1989-05-19 DE DE3916417A patent/DE3916417A1/de active Granted
-
1990
- 1990-05-11 DE DE9090108858T patent/DE59002154D1/de not_active Expired - Fee Related
- 1990-05-11 AT AT90108858T patent/ATE92320T1/de not_active IP Right Cessation
- 1990-05-11 EP EP90108858A patent/EP0398165B1/de not_active Expired - Lifetime
- 1990-05-15 US US07/523,243 patent/US5104875A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE59002154D1 (de) | 1993-09-09 |
| EP0398165B1 (de) | 1993-08-04 |
| EP0398165A1 (de) | 1990-11-22 |
| DE3916417C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1991-08-08 |
| DE3916417A1 (de) | 1990-11-22 |
| US5104875A (en) | 1992-04-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REN | Ceased due to non-payment of the annual fee |