ATE91237T1 - Kombinationen von nekrose-tumor-faktoren und entzuendungshemmenden mitteln fuer die behandlung von boesartigen und nicht boesartigen erkrankungen. - Google Patents
Kombinationen von nekrose-tumor-faktoren und entzuendungshemmenden mitteln fuer die behandlung von boesartigen und nicht boesartigen erkrankungen.Info
- Publication number
- ATE91237T1 ATE91237T1 AT87907079T AT87907079T ATE91237T1 AT E91237 T1 ATE91237 T1 AT E91237T1 AT 87907079 T AT87907079 T AT 87907079T AT 87907079 T AT87907079 T AT 87907079T AT E91237 T1 ATE91237 T1 AT E91237T1
- Authority
- AT
- Austria
- Prior art keywords
- malignant
- combinations
- treatment
- inflammatory agents
- tnf
- Prior art date
Links
- 230000003211 malignant effect Effects 0.000 title abstract 4
- 238000011282 treatment Methods 0.000 title abstract 3
- 201000010099 disease Diseases 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- 206010028980 Neoplasm Diseases 0.000 title 1
- 229940121363 anti-inflammatory agent Drugs 0.000 title 1
- 239000002260 anti-inflammatory agent Substances 0.000 title 1
- 101000611183 Homo sapiens Tumor necrosis factor Proteins 0.000 abstract 4
- 102100040247 Tumor necrosis factor Human genes 0.000 abstract 4
- CGIGDMFJXJATDK-UHFFFAOYSA-N indomethacin Chemical compound CC1=C(CC(O)=O)C2=CC(OC)=CC=C2N1C(=O)C1=CC=C(Cl)C=C1 CGIGDMFJXJATDK-UHFFFAOYSA-N 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 abstract 2
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 abstract 2
- HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 abstract 1
- 108060008682 Tumor Necrosis Factor Proteins 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000009036 growth inhibition Effects 0.000 abstract 1
- 229960001680 ibuprofen Drugs 0.000 abstract 1
- 229960000905 indomethacin Drugs 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 238000011269 treatment regimen Methods 0.000 abstract 1
- 102000003390 tumor necrosis factor Human genes 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/191—Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Rheumatology (AREA)
- Zoology (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91985186A | 1986-10-16 | 1986-10-16 | |
| PCT/US1987/002602 WO1988002632A1 (en) | 1986-10-16 | 1987-10-14 | Combinations of tumor necrosis factors and anti-inflammatory agents and methods for treating malignant and non-malignant diseases |
| EP87907079A EP0287633B1 (de) | 1986-10-16 | 1987-10-14 | Kombinationen von nekrose-tumor-faktoren und entzündungshemmenden mitteln für die behandlung von bösartigen und nicht bösartigen erkrankungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE91237T1 true ATE91237T1 (de) | 1993-07-15 |
Family
ID=25442745
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87907079T ATE91237T1 (de) | 1986-10-16 | 1987-10-14 | Kombinationen von nekrose-tumor-faktoren und entzuendungshemmenden mitteln fuer die behandlung von boesartigen und nicht boesartigen erkrankungen. |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0287633B1 (de) |
| JP (1) | JPH01500905A (de) |
| AT (1) | ATE91237T1 (de) |
| DE (1) | DE3786456T2 (de) |
| IL (1) | IL84189A0 (de) |
| WO (1) | WO1988002632A1 (de) |
| ZA (1) | ZA877771B (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5508031A (en) * | 1986-11-21 | 1996-04-16 | Cetus Oncology Corporation | Method for treating biological damage using a free-radial scavenger and interleukin-2 |
| DE3816169A1 (de) * | 1988-05-11 | 1989-11-23 | Boehringer Ingelheim Kg | Verwendung und mittel zur verminderung der nebenwirkungen von tnf |
| US20030225254A1 (en) | 1989-08-07 | 2003-12-04 | Rathjen Deborah Ann | Tumour necrosis factor binding ligands |
| JP3443119B2 (ja) | 1989-08-07 | 2003-09-02 | ペプテック リミテッド | 腫瘍壊死因子結合リガンド |
| US6042837A (en) * | 1989-09-20 | 2000-03-28 | Kalland; Terje | Methods of staphylococcal enterotoxin directed cell-mediated cytotoxicity (SDCC) |
| US5728388A (en) | 1989-10-03 | 1998-03-17 | Terman; David S. | Method of cancer treatment |
| EP1129717B2 (de) * | 1990-01-17 | 2013-03-06 | TERMAN, David S. | Verwendung von Staphylococcus Enterotoxin Homologe für Krebs-Therapie |
| GB9005856D0 (en) * | 1990-03-15 | 1990-05-09 | Geistlich Soehne Ag | Compositions |
| CA2103045A1 (en) * | 1991-05-14 | 1992-11-15 | Robert J. Leonard | Engineering the local inflammatory response as a means of controlled release drug delivery |
| WO1997048391A2 (en) * | 1996-06-21 | 1997-12-24 | Advanced Research And Technology Institute | Methods and compositions comprising r-ibuprofen |
| RU2145854C1 (ru) * | 1998-09-15 | 2000-02-27 | Ленин Петр Алексеевич | Противоопухолевое средство |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4677064A (en) * | 1984-11-09 | 1987-06-30 | Cetus Corporation | Human tumor necrosis factor |
| EP0271521A4 (de) * | 1986-05-09 | 1989-11-14 | Sloan Kettering Inst Cancer | Zubereitungen von lipopolysacchariden und natürlichem faktor zur antitumortherapie und verfahren zur behandlung. |
-
1987
- 1987-10-14 AT AT87907079T patent/ATE91237T1/de not_active IP Right Cessation
- 1987-10-14 WO PCT/US1987/002602 patent/WO1988002632A1/en not_active Ceased
- 1987-10-14 EP EP87907079A patent/EP0287633B1/de not_active Expired - Lifetime
- 1987-10-14 DE DE87907079T patent/DE3786456T2/de not_active Expired - Fee Related
- 1987-10-14 JP JP62506436A patent/JPH01500905A/ja active Pending
- 1987-10-15 ZA ZA877771A patent/ZA877771B/xx unknown
- 1987-10-16 IL IL84189A patent/IL84189A0/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0287633A1 (de) | 1988-10-26 |
| DE3786456T2 (de) | 1994-02-03 |
| JPH01500905A (ja) | 1989-03-30 |
| DE3786456D1 (de) | 1993-08-12 |
| ZA877771B (en) | 1988-09-28 |
| EP0287633B1 (de) | 1993-07-07 |
| WO1988002632A1 (en) | 1988-04-21 |
| EP0287633A4 (de) | 1989-02-23 |
| IL84189A0 (en) | 1988-03-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |