ATE90563T1 - Arzneimittelzubereitung aus esterderivaten des hecogenins und dessen verwendung zur behandlung von benigner prostatahyperplasie. - Google Patents
Arzneimittelzubereitung aus esterderivaten des hecogenins und dessen verwendung zur behandlung von benigner prostatahyperplasie.Info
- Publication number
- ATE90563T1 ATE90563T1 AT89119837T AT89119837T ATE90563T1 AT E90563 T1 ATE90563 T1 AT E90563T1 AT 89119837 T AT89119837 T AT 89119837T AT 89119837 T AT89119837 T AT 89119837T AT E90563 T1 ATE90563 T1 AT E90563T1
- Authority
- AT
- Austria
- Prior art keywords
- hecogenin
- ester derivatives
- treatment
- medicinal preparation
- benign prostate
- Prior art date
Links
- 206010004446 Benign prostatic hyperplasia Diseases 0.000 title 1
- QOLRLLFJMZLYQJ-LOBDNJQFSA-N Hecogenin Chemical class O([C@@H]1[C@@H]([C@]2(C(=O)C[C@@H]3[C@@]4(C)CC[C@H](O)C[C@@H]4CC[C@H]3[C@@H]2C1)C)[C@@H]1C)[C@]11CC[C@@H](C)CO1 QOLRLLFJMZLYQJ-LOBDNJQFSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- OXLGJTRVVNGJRK-UHFFFAOYSA-N Hecogenin Natural products CC1CCC2(CC3CC4C5CCC6CC(O)CCC6(C)C5CC(=O)C4(C)C3C2C)OC1 OXLGJTRVVNGJRK-UHFFFAOYSA-N 0.000 abstract 1
- 241000282414 Homo sapiens Species 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- UVLDESQWQRMYKD-UHFFFAOYSA-N Neobotogenin Natural products CC1C(C2(C(=O)CC3C4(C)CCC(O)CC4=CCC3C2C2)C)C2OC11CCC(C)CO1 UVLDESQWQRMYKD-UHFFFAOYSA-N 0.000 abstract 1
- 125000005907 alkyl ester group Chemical group 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 230000001364 causal effect Effects 0.000 abstract 1
- 230000010261 cell growth Effects 0.000 abstract 1
- 206010020718 hyperplasia Diseases 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3838716A DE3838716A1 (de) | 1988-11-15 | 1988-11-15 | Arzneimittelzubereitung aus esterderivaten des hecogenins und dessen verwendung zur behandlung von benigner prostatahyperplasie |
| EP89119837A EP0369216B1 (de) | 1988-11-15 | 1989-10-25 | Arzneimittelzubereitung aus Esterderivaten des Hecogenins und dessen Verwendung zur Behandlung von benigner Prostatahyperplasie |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE90563T1 true ATE90563T1 (de) | 1993-07-15 |
Family
ID=6367236
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89119837T ATE90563T1 (de) | 1988-11-15 | 1989-10-25 | Arzneimittelzubereitung aus esterderivaten des hecogenins und dessen verwendung zur behandlung von benigner prostatahyperplasie. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5002939A (enExample) |
| EP (1) | EP0369216B1 (enExample) |
| JP (1) | JP2562210B2 (enExample) |
| AT (1) | ATE90563T1 (enExample) |
| BE (2) | BE1002024A6 (enExample) |
| DE (2) | DE3838716A1 (enExample) |
| ES (1) | ES2057054T3 (enExample) |
| GR (1) | GR3008170T3 (enExample) |
| IT (1) | IT1229272B (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9923076D0 (en) * | 1999-09-29 | 1999-12-01 | Phytopharm Plc | Sapogenin derivatives and their use |
| ATE337788T1 (de) * | 1998-03-26 | 2006-09-15 | Phytopharm Plc | Steroidale saponine zur behandlung der alzheimerischen krankheit |
| US6241987B1 (en) * | 1998-08-20 | 2001-06-05 | Amway Corporation | Dietary supplement containing saw palmetto, pumpkin seed, and nettle root |
| GB9923078D0 (en) * | 1999-09-29 | 1999-12-01 | Phytopharm Plc | Sapogenin derivatives and their use |
| GB9923077D0 (en) * | 1999-09-29 | 1999-12-01 | Phytopharm Plc | Sapogenin derivatives and their use |
| US6261607B1 (en) * | 1999-10-19 | 2001-07-17 | Thomas Newmark | Composition for promoting prostate health containing selenium and herbal extracts |
| GB0000228D0 (en) * | 2000-01-06 | 2000-03-01 | Phytopharm Plc | Fluoro substituted sapogenins and their use |
| GB0107822D0 (en) * | 2001-03-28 | 2001-05-23 | Phytopharm Plc | Sapogenin derivatives their synthesis and use methods based upon their use |
| KR101130212B1 (ko) * | 2002-03-27 | 2012-04-13 | 파이토팜 피엘씨 | 사포게닌 및 그 유도체의 치료 방법 및 사용법 |
| US20050130948A1 (en) * | 2002-03-27 | 2005-06-16 | Daryl Rees | Therapeutic methods and uses of sapogenins and their derivatives |
| TW201006474A (en) | 2008-04-18 | 2010-02-16 | Reata Pharmaceuticals Inc | Natural products including an anti-flammatory pharmacore and methods of use |
| EP3508891A4 (en) * | 2016-08-30 | 2019-11-06 | Panasonic Intellectual Property Management Co., Ltd. | COLOR CONVERSION ELEMENT |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA582813A (en) * | 1959-09-08 | Elks Joseph | 3.beta., 12.beta.-DIHYDROXY-11-OXO-23-BROMO-5.alpha., 22.alpha.-SPIROSTAN | |
| CA985172A (en) * | 1972-10-06 | 1976-03-09 | Dushan M. Dvornik | Compositions and methods for reducing blood cholesterol |
| US3935194A (en) * | 1974-01-22 | 1976-01-27 | Omni Research Incorporated | Separation of hecogenin-tigogenin mixtures |
| DE2759171A1 (de) * | 1977-12-31 | 1979-07-12 | Roecar Holdings Nv | Arzneimittel mit wirkung als prostaglandinsynthetaseninhibitor |
| DE2926463A1 (de) * | 1978-07-05 | 1980-01-24 | Roecar Holdings Nv | Spiroketaline und ihre verwendung |
| GB2024624A (en) * | 1978-07-05 | 1980-01-16 | Roecar Holdings Nv | Anti inflammatory spiroketalins |
| DE3888378T2 (de) * | 1987-04-03 | 1994-09-29 | Merck & Co Inc | Behandlung von Prostatacarcinoma mit 17-beta-n-monosubstituierten-Carbamoyl-4-aza-5-alpha-Androst-1-en-3-onen. |
-
1988
- 1988-11-15 DE DE3838716A patent/DE3838716A1/de active Granted
-
1989
- 1989-04-26 BE BE8900463A patent/BE1002024A6/xx active
- 1989-04-26 BE BE8900463A patent/BE1002504A3/fr not_active IP Right Cessation
- 1989-05-11 IT IT8920466A patent/IT1229272B/it active
- 1989-10-25 AT AT89119837T patent/ATE90563T1/de not_active IP Right Cessation
- 1989-10-25 EP EP89119837A patent/EP0369216B1/de not_active Expired - Lifetime
- 1989-10-25 ES ES89119837T patent/ES2057054T3/es not_active Expired - Lifetime
- 1989-10-25 DE DE8989119837T patent/DE58904722D1/de not_active Expired - Fee Related
- 1989-11-13 US US07/434,344 patent/US5002939A/en not_active Expired - Lifetime
- 1989-11-15 JP JP1297266A patent/JP2562210B2/ja not_active Expired - Fee Related
-
1993
- 1993-06-17 GR GR930400367T patent/GR3008170T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GR3008170T3 (enExample) | 1993-09-30 |
| EP0369216A2 (de) | 1990-05-23 |
| DE58904722D1 (de) | 1993-07-22 |
| EP0369216B1 (de) | 1993-06-16 |
| IT8920466A0 (it) | 1989-05-11 |
| BE1002024A6 (fr) | 1990-05-22 |
| US5002939A (en) | 1991-03-26 |
| IT1229272B (it) | 1991-07-26 |
| JPH02180830A (ja) | 1990-07-13 |
| ES2057054T3 (es) | 1994-10-16 |
| EP0369216A3 (en) | 1990-11-07 |
| JP2562210B2 (ja) | 1996-12-11 |
| BE1002504A3 (fr) | 1991-03-05 |
| DE3838716A1 (de) | 1990-05-17 |
| DE3838716C2 (enExample) | 1990-09-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEFA | Change of the company name | ||
| REN | Ceased due to non-payment of the annual fee |