ATE88185T1 - Verfahren mit hoher ausbeute zur herstellung von beta-lactam-antibiotika mit hoher reinheit. - Google Patents

Verfahren mit hoher ausbeute zur herstellung von beta-lactam-antibiotika mit hoher reinheit.

Info

Publication number
ATE88185T1
ATE88185T1 AT85106308T AT85106308T ATE88185T1 AT E88185 T1 ATE88185 T1 AT E88185T1 AT 85106308 T AT85106308 T AT 85106308T AT 85106308 T AT85106308 T AT 85106308T AT E88185 T1 ATE88185 T1 AT E88185T1
Authority
AT
Austria
Prior art keywords
lactam antibiotics
production
yield process
high purity
purity beta
Prior art date
Application number
AT85106308T
Other languages
English (en)
Inventor
Umberto Valcavi
Vittorio Marotta
Paolo Farina
Original Assignee
Istituto Biochimico Italiano
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Istituto Biochimico Italiano filed Critical Istituto Biochimico Italiano
Application granted granted Critical
Publication of ATE88185T1 publication Critical patent/ATE88185T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT85106308T 1984-07-30 1985-05-22 Verfahren mit hoher ausbeute zur herstellung von beta-lactam-antibiotika mit hoher reinheit. ATE88185T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT22122/84A IT1180207B (it) 1984-07-30 1984-07-30 Procedimento per la preparazione, con resa e purezza elevate, di antibiotici beta-lattamici
EP85106308A EP0169995B1 (de) 1984-07-30 1985-05-22 Verfahren mit hoher Ausbeute zur Herstellung von Beta-Lactam-Antibiotika mit hoher Reinheit

Publications (1)

Publication Number Publication Date
ATE88185T1 true ATE88185T1 (de) 1993-04-15

Family

ID=11191815

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85106308T ATE88185T1 (de) 1984-07-30 1985-05-22 Verfahren mit hoher ausbeute zur herstellung von beta-lactam-antibiotika mit hoher reinheit.

Country Status (6)

Country Link
US (1) US4625021A (de)
EP (1) EP0169995B1 (de)
JP (2) JPS6137787A (de)
AT (1) ATE88185T1 (de)
DE (2) DE3587258D1 (de)
IT (1) IT1180207B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3542644A1 (de) * 1985-12-03 1987-06-04 Hoechst Ag Verfahren zur herstellung von cefodizim
HU221200B1 (en) * 1990-01-22 2002-08-28 Biochemie Gmbh Process for producing beta-lactames
GB9423459D0 (en) * 1994-11-21 1995-01-11 Biochemie Gmbh Silylation process
CA2216259A1 (en) * 1996-09-25 1998-03-25 Eisai Chemical Co., Ltd. Production process of cephem compound

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1364672A (en) * 1971-06-09 1974-08-29 Beecham Group Ltd Penicillins
GB1472746A (en) * 1973-07-05 1977-05-04 Glaxo Lab Ltd Cephalosporin compounds
US3954745A (en) * 1974-09-12 1976-05-04 Eli Lilly And Company Process for preparing cefazolin
GB1536281A (en) * 1975-06-09 1978-12-20 Takeda Chemical Industries Ltd Cephem compounds
GB1459807A (en) * 1975-05-27 1976-12-31 Proter Spa Process for the production of 7-d-a-amino-phenyl-acetamido-3- desacetoxy-cephalosporanic acid
JPS5285185A (en) * 1976-01-05 1977-07-15 Teijin Ltd Preparation of 7-acylaminocephalosporanic acids
US4182709A (en) * 1976-01-15 1980-01-08 Glaxo Group Limited Manufacture of semi-synthetic penicillin antibiotics
CA1125745A (en) * 1978-11-20 1982-06-15 Joseph Kaspi PROCESS FOR PREPARING .beta.-LACTAM ANTIBIOTICS
JPS5572194A (en) * 1978-11-20 1980-05-30 Plantex Ltd Manufacture of alphaaaminopenicillin
US4248780A (en) * 1979-08-21 1981-02-03 Canada Packers Limited Process for preparing ampicillin
JPS5821682A (ja) * 1981-07-31 1983-02-08 Sankyo Co Ltd セファロスポリン誘導体
JPS5965094A (ja) * 1982-10-06 1984-04-13 Sumitomo Chem Co Ltd セフアロスポリン化合物の製造法

Also Published As

Publication number Publication date
DE3587258T4 (de) 1994-05-26
JPH0327386A (ja) 1991-02-05
EP0169995A2 (de) 1986-02-05
JPS6137787A (ja) 1986-02-22
IT8422122A0 (it) 1984-07-30
EP0169995B1 (de) 1993-04-14
IT1180207B (it) 1987-09-23
EP0169995A3 (en) 1987-04-22
DE3587258T2 (de) 1993-08-12
US4625021A (en) 1986-11-25
DE3587258D1 (de) 1993-05-19

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