ATE78822T1 - Benzo(i,j>chinolizin-2-carbonsaeurederivate, ihre salze und hydrate, diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung. - Google Patents
Benzo(i,j>chinolizin-2-carbonsaeurederivate, ihre salze und hydrate, diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung.Info
- Publication number
- ATE78822T1 ATE78822T1 AT86303948T AT86303948T ATE78822T1 AT E78822 T1 ATE78822 T1 AT E78822T1 AT 86303948 T AT86303948 T AT 86303948T AT 86303948 T AT86303948 T AT 86303948T AT E78822 T1 ATE78822 T1 AT E78822T1
- Authority
- AT
- Austria
- Prior art keywords
- sup
- quinolizine
- hydrates
- benzo
- salts
- Prior art date
Links
- 150000004677 hydrates Chemical class 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000000954 2-hydroxyethyl group Chemical group [H]C([*])([H])C([H])([H])O[H] 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 125000005605 benzo group Chemical group 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 125000005678 ethenylene group Chemical group [H]C([*:1])=C([H])[*:2] 0.000 abstract 1
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 230000005923 long-lasting effect Effects 0.000 abstract 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11022685 | 1985-05-24 | ||
| JP11022785 | 1985-05-24 | ||
| EP86303948A EP0203795B1 (de) | 1985-05-24 | 1986-05-23 | Benzo[i,j]chinolizin-2-carbonsäurederivate, ihre Salze und Hydrate, diese enthaltende pharmazeutische Zubereitungen und Verfahren zu ihrer Herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE78822T1 true ATE78822T1 (de) | 1992-08-15 |
Family
ID=26449894
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT86303948T ATE78822T1 (de) | 1985-05-24 | 1986-05-23 | Benzo(i,j>chinolizin-2-carbonsaeurederivate, ihre salze und hydrate, diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4720495A (de) |
| EP (1) | EP0203795B1 (de) |
| AT (1) | ATE78822T1 (de) |
| AU (1) | AU585981B2 (de) |
| CA (1) | CA1253154A (de) |
| DE (1) | DE3686201T2 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4929613A (en) * | 1987-08-26 | 1990-05-29 | Warner-Lambert Company | Antibacterial agents |
| JPH01250380A (ja) * | 1987-12-26 | 1989-10-05 | Tokyo Tanabe Co Ltd | 光学活性ベンゾキノリジン誘導体、その製造方法およびそれを有効成分とする抗菌剤 |
| AU623474B2 (en) * | 1989-01-16 | 1992-05-14 | Laboratoire Roger Bellon | New benzo(1,8)naphthyridine derivatives, their preparation and compositions containing them |
| US4948894A (en) * | 1989-02-21 | 1990-08-14 | American Cyanamid Company | 8-fluoro and 7, 8, 10-trifluoro-9-(substituted)-6-oxo-6H-benzo-(C)quinolizine-5-carboxylic acids |
| US4923868A (en) * | 1989-02-21 | 1990-05-08 | American Cyanamid Company | 8-fluoro and 7,8,10-trifluoro-9-(substituted)-6-oxo-6H-benzo(C)quinolizine-5-carboxylic acids |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4014877A (en) * | 1972-11-02 | 1977-03-29 | Riker Laboratories, Inc. | Substituted benzo[ij]quinolizine-2-carboxylic acids and derivatives thereof |
| JPS5040616A (de) * | 1973-07-06 | 1975-04-14 | ||
| ES446538A1 (es) * | 1975-04-14 | 1977-10-16 | Riker Laboratories Inc | Procedimiento para preparar benzoquinoliznios sustituidos. |
| US4416884A (en) * | 1978-04-12 | 1983-11-22 | Otsuka Pharmaceutical Co., Ltd. | Piperazinylbenzoheterocyclic compounds |
| DE2953974C2 (de) * | 1978-04-12 | 1992-06-25 | Otsuka Pharmaceutical Co., Ltd., Tokio/Tokyo, Jp | |
| JPS6019910B2 (ja) * | 1979-10-11 | 1985-05-18 | 大塚製薬株式会社 | ベンゾ〔ｉｊ〕キノリジン−２−カルボン酸誘導体及びその製造法 |
| JPS5746986A (en) * | 1980-09-02 | 1982-03-17 | Dai Ichi Seiyaku Co Ltd | Pyrido(1,2,3-de)(1,4)benzoxazine derivative |
| NO156828C (no) * | 1980-11-10 | 1987-12-02 | Otsuka Pharma Co Ltd | Analogifremgangsm te for fremstilling av antibakterielt virksomme benzoheterocykliske forbindelser. |
| PT74145B (en) * | 1980-12-18 | 1983-05-30 | Otsuka Pharma Co Ltd | Process for preparing benzoheterocyclic compounds |
| JPS59106488A (ja) * | 1982-12-10 | 1984-06-20 | Dai Ichi Seiyaku Co Ltd | ベンゾキノリジン誘導体 |
| JPS59137482A (ja) * | 1983-01-26 | 1984-08-07 | Otsuka Pharmaceut Co Ltd | ピロロ〔３，２，１，−ｉｊ〕キノリン−５−カルボン酸誘導体 |
| US4659734A (en) * | 1983-08-15 | 1987-04-21 | Nippon Shinyaku Co., Ltd. | Olinecarboxylic acid derivatives |
-
1986
- 1986-05-15 AU AU57484/86A patent/AU585981B2/en not_active Ceased
- 1986-05-15 CA CA000509221A patent/CA1253154A/en not_active Expired
- 1986-05-20 US US06/865,530 patent/US4720495A/en not_active Expired - Fee Related
- 1986-05-23 AT AT86303948T patent/ATE78822T1/de not_active IP Right Cessation
- 1986-05-23 DE DE8686303948T patent/DE3686201T2/de not_active Expired - Fee Related
- 1986-05-23 EP EP86303948A patent/EP0203795B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE3686201D1 (de) | 1992-09-03 |
| US4720495A (en) | 1988-01-19 |
| EP0203795B1 (de) | 1992-07-29 |
| EP0203795A2 (de) | 1986-12-03 |
| AU5748486A (en) | 1986-11-27 |
| CA1253154A (en) | 1989-04-25 |
| DE3686201T2 (de) | 1993-01-07 |
| AU585981B2 (en) | 1989-06-29 |
| EP0203795A3 (en) | 1988-02-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |