ATE78252T1 - Dihydropyridine und ihre verwendung als antiallergische und entzuendungshemmende mittel. - Google Patents

Dihydropyridine und ihre verwendung als antiallergische und entzuendungshemmende mittel.

Info

Publication number
ATE78252T1
ATE78252T1 AT89301328T AT89301328T ATE78252T1 AT E78252 T1 ATE78252 T1 AT E78252T1 AT 89301328 T AT89301328 T AT 89301328T AT 89301328 T AT89301328 T AT 89301328T AT E78252 T1 ATE78252 T1 AT E78252T1
Authority
AT
Austria
Prior art keywords
alkyl
alkoxy
piperazinyl
aryl
phenyl
Prior art date
Application number
AT89301328T
Other languages
English (en)
Inventor
Kelvin Dr Cooper
John Dr Steele
Kenneth Dr Richardson
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Application granted granted Critical
Publication of ATE78252T1 publication Critical patent/ATE78252T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
AT89301328T 1988-02-19 1989-02-13 Dihydropyridine und ihre verwendung als antiallergische und entzuendungshemmende mittel. ATE78252T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888803963A GB8803963D0 (en) 1988-02-19 1988-02-19 Therapeutic agents
EP89301328A EP0329357B1 (de) 1988-02-19 1989-02-13 Dihydropyridine und ihre Verwendung als anti-allergische und entzündungshemmende Mittel

Publications (1)

Publication Number Publication Date
ATE78252T1 true ATE78252T1 (de) 1992-08-15

Family

ID=10632051

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89301328T ATE78252T1 (de) 1988-02-19 1989-02-13 Dihydropyridine und ihre verwendung als antiallergische und entzuendungshemmende mittel.

Country Status (12)

Country Link
US (1) US4859686A (de)
EP (1) EP0329357B1 (de)
JP (1) JPH01254665A (de)
AT (1) ATE78252T1 (de)
DE (1) DE68902064T2 (de)
DK (1) DK71789A (de)
ES (1) ES2042997T3 (de)
FI (1) FI890775A (de)
GB (1) GB8803963D0 (de)
GR (1) GR3005472T3 (de)
IE (1) IE890521L (de)
PT (1) PT89747B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY104933A (en) * 1987-09-30 1994-07-30 Pfizer Ltd Platelet activating factor antagonists
AU692619B2 (en) * 1994-11-29 1998-06-11 Gallagher Group Limited Method of electronic control
DE60234057D1 (de) 2001-07-25 2009-11-26 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
CN103259027A (zh) 2005-04-28 2013-08-21 普罗透斯数字保健公司 药物信息系统
EP2063905B1 (de) 2006-09-18 2014-07-30 Raptor Pharmaceutical Inc Behandlungen von lebererkrankungen durch verabreichung von konjugaten aus rezeptor-assoziierten proteinen
PL3395372T3 (pl) 2009-02-20 2022-07-25 EnhanX Biopharm Inc. Układ do dostarczania leków na bazie glutationu
KR20190116576A (ko) 2009-05-06 2019-10-14 라보라토리 스킨 케어, 인크. 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4515799A (en) * 1983-02-02 1985-05-07 Pfizer Inc. Dihydropyridine anti-ischaemic and antihypertensive agents
GB8620880D0 (en) * 1986-08-29 1986-10-08 Pfizer Ltd Therapeutic agents

Also Published As

Publication number Publication date
IE890521L (en) 1989-08-19
EP0329357B1 (de) 1992-07-15
FI890775A (fi) 1989-08-20
GR3005472T3 (de) 1993-05-24
DE68902064T2 (de) 1992-12-03
JPH01254665A (ja) 1989-10-11
FI890775A0 (fi) 1989-02-17
DK71789A (da) 1989-08-21
PT89747B (pt) 1994-03-31
DK71789D0 (da) 1989-02-16
EP0329357A1 (de) 1989-08-23
DE68902064D1 (de) 1992-08-20
US4859686A (en) 1989-08-22
ES2042997T3 (es) 1993-12-16
PT89747A (pt) 1989-10-04
GB8803963D0 (en) 1988-03-23

Similar Documents

Publication Publication Date Title
EP0258033B1 (en) Dihydropyridine anti-allergic and anti-inflammatory agents
ES2034221T3 (es) Agentes antialergicos y antiinflamatorios de dihidropiridina.
ATE174917T1 (de) Pyrazolo(1,5-a>pyrimidinderivate und sie enthaltende antiinflammatorische mittel
ATE78252T1 (de) Dihydropyridine und ihre verwendung als antiallergische und entzuendungshemmende mittel.
MY104933A (en) Platelet activating factor antagonists
ATE173733T1 (de) Antimikrobielle carbapenem-derivate, ihre herstellung und ihre therapeutische verwendung
DE69910568D1 (de) Furopyridinderivate und ihre therapeutische verwendung
ATE122044T1 (de) Pyrrolo(1,2-a>imidazol- und imidazo(1,2- a>pyridinderivate und ihre anwendung als 5- lipoxygenase inhibitoren.
IE870141L (en) Dihydropyridine anti-ischaemic antihypertensive¹agents

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee