ATE77372T1 - 1,4-dihydropyridinderivate. - Google Patents

1,4-dihydropyridinderivate.

Info

Publication number
ATE77372T1
ATE77372T1 AT87301435T AT87301435T ATE77372T1 AT E77372 T1 ATE77372 T1 AT E77372T1 AT 87301435 T AT87301435 T AT 87301435T AT 87301435 T AT87301435 T AT 87301435T AT E77372 T1 ATE77372 T1 AT E77372T1
Authority
AT
Austria
Prior art keywords
alkyl group
alkyl
group
straight
branched
Prior art date
Application number
AT87301435T
Other languages
English (en)
Inventor
Claudio Semeraro
Dino Micheli
Daniele Pieraccioli
Giovanni Gaviraghi
Alan David Borthwick
Original Assignee
Glaxo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Spa filed Critical Glaxo Spa
Application granted granted Critical
Publication of ATE77372T1 publication Critical patent/ATE77372T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Catching Or Destruction (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT87301435T 1986-02-20 1987-02-19 1,4-dihydropyridinderivate. ATE77372T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT8619486A IT1204462B (it) 1986-02-20 1986-02-20 Derivati eterociclici
EP87301435A EP0245919B1 (de) 1986-02-20 1987-02-19 1,4-Dihydropyridinderivate

Publications (1)

Publication Number Publication Date
ATE77372T1 true ATE77372T1 (de) 1992-07-15

Family

ID=11158430

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87301435T ATE77372T1 (de) 1986-02-20 1987-02-19 1,4-dihydropyridinderivate.

Country Status (6)

Country Link
US (2) US4806533A (de)
EP (1) EP0245919B1 (de)
JP (1) JPS62252770A (de)
AT (1) ATE77372T1 (de)
DE (1) DE3779813T2 (de)
IT (1) IT1204462B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL192385C (nl) * 1985-08-21 1997-07-04 Glaxo Spa 6-alkyl-4-fenyl-1,4-dihydro-3,5-pyridinecarbonzuuresters, werkwijze voor de bereiding daarvan en farmaceutische preparaten die deze esters bevatten.
IT1204460B (it) * 1986-02-20 1989-03-01 Glaxo Spa Derivati eterociclici
US5216172A (en) * 1988-02-24 1993-06-01 Ajinomoto Co., Inc. 1,4-dihydropyridine-4-aryl-2,6-dimethyl-3,5-dicarboxylates useful as agents against drug resistant tumor cells
EP0330470A3 (de) * 1988-02-24 1992-01-02 Ajinomoto Co., Inc. Gegen Tumorzellen verwendbare 1,4-Dihydropyridin-Derivate
US20070043088A1 (en) * 2005-08-16 2007-02-22 Eswaraiah Sajja Process for preparing lacidipine
US20080089947A1 (en) * 2006-08-18 2008-04-17 Knox Clayton D Calcium Influx Inhibitors in the Treatment of Ischemia

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3455945A (en) * 1967-06-07 1969-07-15 Smithkline Corp 4-(carboxy (and carbo-lower alkoxy)phenyl)-1,4-dihydropyridines
DE2228363A1 (de) * 1972-06-10 1974-01-03 Bayer Ag 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
GB1409865A (en) * 1973-02-13 1975-10-15 Science Union & Cie Dihydropyridines derivatives their preparation and pharmaceu tical compositions containing them
NZ201395A (en) * 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
DE3207982A1 (de) * 1982-03-05 1983-09-08 Bayer Ag, 5090 Leverkusen Neue 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihrer verwendung in arzneimitteln
NZ212895A (en) * 1984-08-22 1988-07-28 Glaxo Spa 1,4-dihydropyridine derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
DE3779813D1 (en) 1992-07-23
IT8619486A0 (it) 1986-02-20
IT1204462B (it) 1989-03-01
JPS62252770A (ja) 1987-11-04
DE3779813T2 (de) 1992-12-24
EP0245919B1 (de) 1992-06-17
US4963571A (en) 1990-10-16
US4806533A (en) 1989-02-21
EP0245919A1 (de) 1987-11-19

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