ATE76975T1 - Polynukleotid-hybridisationsproben mit katalysierter lumineszenz. - Google Patents
Polynukleotid-hybridisationsproben mit katalysierter lumineszenz.Info
- Publication number
- ATE76975T1 ATE76975T1 AT85309224T AT85309224T ATE76975T1 AT E76975 T1 ATE76975 T1 AT E76975T1 AT 85309224 T AT85309224 T AT 85309224T AT 85309224 T AT85309224 T AT 85309224T AT E76975 T1 ATE76975 T1 AT E76975T1
- Authority
- AT
- Austria
- Prior art keywords
- catalyst
- polynucleotide
- apoluminescer
- luminescer
- sample
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/683,947 US4670379A (en) | 1984-12-19 | 1984-12-19 | Polynucleotide hydridization assays employing catalyzed luminescence |
EP85309224A EP0185547B1 (de) | 1984-12-19 | 1985-12-18 | Polynukleotid-Hybridisationsproben mit katalysierter Lumineszenz |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE76975T1 true ATE76975T1 (de) | 1992-06-15 |
Family
ID=24746104
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT85309224T ATE76975T1 (de) | 1984-12-19 | 1985-12-18 | Polynukleotid-hybridisationsproben mit katalysierter lumineszenz. |
Country Status (9)
Country | Link |
---|---|
US (1) | US4670379A (de) |
EP (1) | EP0185547B1 (de) |
JP (1) | JPS61146198A (de) |
AT (1) | ATE76975T1 (de) |
CA (1) | CA1293937C (de) |
DE (1) | DE3586170T2 (de) |
DK (1) | DK590885A (de) |
GR (1) | GR853075B (de) |
IE (1) | IE58326B1 (de) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE88761T1 (de) * | 1986-01-10 | 1993-05-15 | Amoco Corp | Kompetitiver homogener test. |
US4935357A (en) * | 1986-02-05 | 1990-06-19 | New England Biolabs, Inc. | Universal restriction endonuclease |
SE454781B (sv) * | 1986-10-17 | 1988-05-30 | Wallac Oy | Hybridiseringsforfarande for detektion av polynukleotidsekvens |
US5714380A (en) | 1986-10-23 | 1998-02-03 | Amoco Corporation | Closed vessel for isolating target molecules and for performing amplification |
US4946786A (en) * | 1987-01-14 | 1990-08-07 | President And Fellows Of Harvard College | T7 DNA polymerase |
US5145776A (en) * | 1987-01-14 | 1992-09-08 | President & Fellows Of Harvard College | Method of using T7 DNA polymerase to mutagenize and fill-in DNA |
US4942130A (en) * | 1987-01-14 | 1990-07-17 | President & Fellows Of Harvard College | T7 DNA polymerase |
US4994372A (en) * | 1987-01-14 | 1991-02-19 | President And Fellows Of Harvard College | DNA sequencing |
US5266466A (en) * | 1987-01-14 | 1993-11-30 | President And Fellows Of Harvard College | Method of using T7 DNA polymerase to label the 3' end of a DNA molecule |
US4795699A (en) * | 1987-01-14 | 1989-01-03 | President And Fellows Of Harvard College | T7 DNA polymerase |
US4962029A (en) * | 1987-10-02 | 1990-10-09 | Cetus Corporation | Covalent oligonucleotide-horseradish peroxidase conjugate |
US5359100A (en) * | 1987-10-15 | 1994-10-25 | Chiron Corporation | Bifunctional blocked phosphoramidites useful in making nucleic acid mutimers |
US5124246A (en) * | 1987-10-15 | 1992-06-23 | Chiron Corporation | Nucleic acid multimers and amplified nucleic acid hybridization assays using same |
EP0343955A3 (de) * | 1988-05-27 | 1990-04-18 | Bioventures, Inc. | Verfahren zur Bindung von Komplexen beabsichtigter Molekularspezies |
FR2644163B2 (fr) * | 1988-07-13 | 1994-09-30 | Bioprobe Systems Sa | Procede de marquage d'une sonde nucleique et trousse de reactifs pour la mise en oeuvre de ce procede |
FR2634211B1 (fr) * | 1988-07-13 | 1992-06-26 | Lebacq Philippe | Procede de marquage d'une sonde nucleique et trousse de reactifs pour la mise en oeuvre de ce procede |
US5858652A (en) * | 1988-08-30 | 1999-01-12 | Abbott Laboratories | Detection and amplification of target nucleic acid sequences |
GB2225112A (en) * | 1988-11-22 | 1990-05-23 | Ici Plc | Hybridisation probes |
US5324829A (en) * | 1988-12-16 | 1994-06-28 | Ortho Diagnostic Systems, Inc. | High specific activity nucleic acid probes having target recognition and signal generating moieties |
US4983511A (en) * | 1989-01-09 | 1991-01-08 | Olin Corporation | Method and kit for detecting live microorganisms in chlorine- or bromine-treated water |
JPH04504059A (ja) * | 1989-03-10 | 1992-07-23 | ミリポア・コーポレーシヨン | 化学発光検出を用いた核酸の配列決定 |
US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
US5744101A (en) * | 1989-06-07 | 1998-04-28 | Affymax Technologies N.V. | Photolabile nucleoside protecting groups |
US5800992A (en) | 1989-06-07 | 1998-09-01 | Fodor; Stephen P.A. | Method of detecting nucleic acids |
ATE262374T1 (de) * | 1991-11-22 | 2004-04-15 | Affymetrix Inc | Kombinatorische strategien für polymersynthese |
US7625697B2 (en) | 1994-06-17 | 2009-12-01 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for constructing subarrays and subarrays made thereby |
US5731148A (en) * | 1995-06-07 | 1998-03-24 | Gen-Probe Incorporated | Adduct protection assay |
EP0795610A1 (de) * | 1996-03-13 | 1997-09-17 | Becton, Dickinson and Company | Amplifiziertes "in situ" Hybridationssignal mittels biotinilierter tyraminen Abscheidung |
DE19850594A1 (de) * | 1998-11-03 | 2000-05-04 | Biochip Technologies Gmbh | Verfahren zur Markierung von Nukleinsäuren |
US7445891B2 (en) * | 2001-07-23 | 2008-11-04 | John-Stephen Taylor | Nucleic acid triggered catalytic drug and probe release |
US7282330B2 (en) * | 2002-05-28 | 2007-10-16 | U.S. Genomics, Inc. | Methods and apparati using single polymer analysis |
EP1527175B1 (de) * | 2002-06-24 | 2009-05-27 | Exiqon A/S | Methoden und systeme zur detektion und isolation von nucleinsäuresequenzen |
GB201003594D0 (en) * | 2010-03-04 | 2010-04-21 | Eluceda Ltd | Method for detecting the presence of specific micro-organisms and device for the same |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2422956A1 (fr) * | 1978-04-13 | 1979-11-09 | Pasteur Institut | Procede de detection et de caracterisation d'un acide nucleique ou d'une sequence de celui-ci, et reactif enzymatique pour la mise en oeuvre de ce procede |
US4238565A (en) * | 1978-06-22 | 1980-12-09 | Miles Laboratories, Inc. | Specific binding assay with a prosthetic group as a label component |
US4358535A (en) * | 1980-12-08 | 1982-11-09 | Board Of Regents Of The University Of Washington | Specific DNA probes in diagnostic microbiology |
CA1219824A (en) * | 1981-04-17 | 1987-03-31 | David C. Ward | Modified nucleotides and methods of preparing and using same |
US4366243A (en) * | 1981-04-17 | 1982-12-28 | Miles Laboratories, Inc. | Stabilization of glucose oxidase apoenzyme |
JPS5840099A (ja) * | 1981-07-17 | 1983-03-08 | アモコ・コ−ポレ−ション | 光−放射ポリヌクレオチドの交雑診断方法 |
CA1180647A (en) * | 1981-07-17 | 1985-01-08 | Cavit Akin | Light-emitting polynucleotide hybridization diagnostic method |
CA1190838A (en) * | 1981-07-17 | 1985-07-23 | Cavit Akin | Homogeneous nucleic acid hybridization diagnostics by non-radiative energy transfer |
FI63596C (fi) * | 1981-10-16 | 1983-07-11 | Orion Yhtymae Oy | Mikrobdiagnostiskt foerfarande som grundar sig pao skiktshybridisering av nukleinsyror och vid foerfarandet anvaenda kombinationer av reagenser |
FR2518755B1 (fr) * | 1981-12-23 | 1986-04-11 | Pasteur Institut | Sonde contenant un acide nucleique modifie et reconnaissable par des anticorps specifiques et utilisation de cette sonde pour detecter et caracteriser une sequence d'adn homologue |
FR2519005B1 (fr) * | 1981-12-29 | 1985-10-25 | Pasteur Institut | Fragments d'adn marques a l'une au moins de leurs extremites par des ribonucleotides modifies reconnaissables par des molecules affines et procede pour realiser une analyse de tels fragments d'adn |
CA1223831A (en) * | 1982-06-23 | 1987-07-07 | Dean Engelhardt | Modified nucleotides, methods of preparing and utilizing and compositions containing the same |
US4556643A (en) * | 1982-07-26 | 1985-12-03 | Agracetus | Assay method and probe for polynucleotide sequences |
WO1984001174A1 (en) * | 1982-09-20 | 1984-03-29 | Harvard College | Identification of microorganisms |
US4857455A (en) * | 1982-11-26 | 1989-08-15 | Syntex (U.S.A) Inc. | Method for the determination of peroxidase using fluorogenic substrates |
EP0756010B1 (de) * | 1983-01-10 | 2001-07-04 | Gen-Probe Incorporated | Verfahren zum Nachweis, Identifizieren und Quantifizieren von Organismen und Viren |
IL70765A (en) * | 1983-01-27 | 1988-07-31 | Enzo Biochem Inc | Substrates containing non-radioactive chemically-labeled polynucleotides and methods using them |
GB8306426D0 (en) * | 1983-03-09 | 1983-04-13 | Malcolm A D B | Detecting polynucleotide sequence |
CA1254525A (en) * | 1983-04-13 | 1989-05-23 | Christine L. Brakel | Kit for terminally chemically labeling dna |
GB8311905D0 (en) * | 1983-04-29 | 1983-06-02 | Cox R A | Isolation and detection of nucleotide sequence |
ATE78301T1 (de) * | 1983-05-31 | 1992-08-15 | Orgenics Ltd | Molekulare genetische sonde und verfahren zu ihrer herstellung, testmethode und satz in denen diese molekulare genetische sonde gebraucht wird. |
EP0128042A3 (de) * | 1983-06-06 | 1985-01-16 | Genentech, Inc. | Verfahren zur Identifizierung oder Isolierung einer DNS-Sequenz und eine dazu verwendete DNS-Hybridizierungsprobe |
-
1984
- 1984-12-19 US US06/683,947 patent/US4670379A/en not_active Expired - Fee Related
-
1985
- 1985-12-17 CA CA000497829A patent/CA1293937C/en not_active Expired - Lifetime
- 1985-12-18 JP JP60283152A patent/JPS61146198A/ja active Pending
- 1985-12-18 DE DE8585309224T patent/DE3586170T2/de not_active Expired - Lifetime
- 1985-12-18 AT AT85309224T patent/ATE76975T1/de active
- 1985-12-18 GR GR853075A patent/GR853075B/el unknown
- 1985-12-18 DK DK590885A patent/DK590885A/da not_active Application Discontinuation
- 1985-12-18 EP EP85309224A patent/EP0185547B1/de not_active Expired - Lifetime
- 1985-12-18 IE IE320985A patent/IE58326B1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JPS61146198A (ja) | 1986-07-03 |
EP0185547A2 (de) | 1986-06-25 |
EP0185547B1 (de) | 1992-06-03 |
DE3586170D1 (de) | 1992-07-09 |
GR853075B (de) | 1986-04-21 |
DK590885D0 (da) | 1985-12-18 |
IE58326B1 (en) | 1993-09-08 |
DK590885A (da) | 1986-06-20 |
IE853209L (en) | 1986-06-19 |
DE3586170T2 (de) | 1992-12-03 |
US4670379A (en) | 1987-06-02 |
EP0185547A3 (en) | 1987-12-09 |
CA1293937C (en) | 1992-01-07 |
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