ATE73345T1 - Anregung zur heilung einer wunde mittels menschlichen hautwachstumsfaktors hergestellt durch rekombinant-dns. - Google Patents
Anregung zur heilung einer wunde mittels menschlichen hautwachstumsfaktors hergestellt durch rekombinant-dns.Info
- Publication number
- ATE73345T1 ATE73345T1 AT85905362T AT85905362T ATE73345T1 AT E73345 T1 ATE73345 T1 AT E73345T1 AT 85905362 T AT85905362 T AT 85905362T AT 85905362 T AT85905362 T AT 85905362T AT E73345 T1 ATE73345 T1 AT E73345T1
- Authority
- AT
- Austria
- Prior art keywords
- growth factor
- heal
- stimulation
- wound
- recombinant dna
- Prior art date
Links
- 108020004511 Recombinant DNA Proteins 0.000 title 1
- 239000003102 growth factor Substances 0.000 title 1
- 230000008470 skin growth Effects 0.000 title 1
- 230000000638 stimulation Effects 0.000 title 1
- 238000000034 method Methods 0.000 abstract 2
- 101500025419 Homo sapiens Epidermal growth factor Proteins 0.000 abstract 1
- 206010052428 Wound Diseases 0.000 abstract 1
- 208000027418 Wounds and injury Diseases 0.000 abstract 1
- 229940116978 human epidermal growth factor Drugs 0.000 abstract 1
- GVUGOAYIVIDWIO-UFWWTJHBSA-N nepidermin Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CS)NC(=O)[C@H](C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CCSC)NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CS)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CS)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(N)=O)C(C)C)[C@@H](C)CC)C(C)C)C(C)C)C1=CC=C(O)C=C1 GVUGOAYIVIDWIO-UFWWTJHBSA-N 0.000 abstract 1
- 230000008929 regeneration Effects 0.000 abstract 1
- 238000011069 regeneration method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/485—Epidermal growth factor [EGF], i.e. urogastrone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Ophthalmology & Optometry (AREA)
- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66309284A | 1984-10-19 | 1984-10-19 | |
| PCT/US1985/002024 WO1986002271A1 (en) | 1984-10-19 | 1985-10-16 | Promotion of wound healing with human epidermal growth factor prepared from recombinant dna |
| EP85905362A EP0200757B1 (de) | 1984-10-19 | 1985-10-16 | Anregung zur heilung einer wunde mittels menschlichen hautwachstumsfaktors hergestellt durch rekombinant-dns |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE73345T1 true ATE73345T1 (de) | 1992-03-15 |
Family
ID=24660436
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT85905362T ATE73345T1 (de) | 1984-10-19 | 1985-10-16 | Anregung zur heilung einer wunde mittels menschlichen hautwachstumsfaktors hergestellt durch rekombinant-dns. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4959353A (de) |
| EP (1) | EP0200757B1 (de) |
| JP (1) | JPH0611709B2 (de) |
| AT (1) | ATE73345T1 (de) |
| DE (1) | DE3585618D1 (de) |
| WO (1) | WO1986002271A1 (de) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8507666D0 (en) * | 1985-03-25 | 1985-05-01 | Wellcome Found | Epidermal growth factor production |
| US4743679A (en) * | 1986-02-24 | 1988-05-10 | Creative Biomolecules, Inc. | Process for producing human epidermal growth factor and analogs thereof |
| US5472702A (en) * | 1987-08-26 | 1995-12-05 | United States Surgical Corporation | Sterilization of growth factors |
| US5366081A (en) * | 1987-08-26 | 1994-11-22 | United States Surgical Corporation | Packaged synthetic absorbable surgical elements |
| EP0339905A3 (de) * | 1988-04-25 | 1991-05-08 | Ethicon, Inc. | Wachstumfaktoren und Retinoiden enthaltende Wundheilungzusammensetzungen |
| US5102789A (en) * | 1989-03-15 | 1992-04-07 | The Salk Institute Biotechnology/Industrial Associates, Inc. | Production of epideramal growth factor in pichia pastoris yeast cells |
| US5124392A (en) * | 1988-10-03 | 1992-06-23 | Alcon Laboratories, Inc. | Pharmaceutical compositions and methods of treatment to prevent and treat corneal scar formation produced by laser irradiation |
| US5360611A (en) * | 1988-10-03 | 1994-11-01 | Alcon Laboratories, Inc. | Pharmaceutical compositions and methods of treatment of the cornea following ultraviolet laser irradiation |
| US5271939A (en) * | 1988-10-03 | 1993-12-21 | Alcon Laboratories, Inc. | Pharmaceutical compositions and methods of treatment to prevent and treat corneal scar formation produced by laser irradiation |
| US4939135A (en) * | 1988-10-03 | 1990-07-03 | Alcon Laboratories, Inc. | Pharmaceutical compositions and methods of treatment to prevent and treat corneal scar formation produced by laser irradiation |
| US5242902A (en) * | 1989-09-06 | 1993-09-07 | The Regents Of The University Of California | Defensin peptide compositions and methods for their use |
| WO1991005863A1 (en) * | 1989-10-11 | 1991-05-02 | Pitman-Moore Australia Limited | Recombinant growth factors |
| US5597798A (en) * | 1990-03-05 | 1997-01-28 | The Regents Of The University Of California | Taxol and epidermal growth factor used to enhance treatment of ovarian cancer |
| US5252342A (en) * | 1990-03-05 | 1993-10-12 | The Regents Of The University Of California | Enhancement of anti-neoplastic drug efficacy using EGF |
| US20030186913A1 (en) * | 1990-03-21 | 2003-10-02 | Vical Incorporated | Expression of exogenous polynucleotide sequences in a vertebrate |
| IT1240683B (it) * | 1990-04-26 | 1993-12-17 | Zambon Spa | Composizione farmaceutica contenente egf |
| US5219998A (en) * | 1990-06-04 | 1993-06-15 | Levin Robert H | Yeast-derived epidermal growth factor |
| US5434135A (en) * | 1990-08-02 | 1995-07-18 | Indu Parikh | Growth factor compositions, preparation and use |
| US5360790A (en) * | 1990-12-11 | 1994-11-01 | The Regents Of The University Of Michigan | Method and formulations for the therapy of acute renal failure |
| CA2059245C (en) * | 1991-02-08 | 2004-07-06 | Michael P. Chesterfield | Method and apparatus for calendering and coating/filling sutures |
| WO1993007891A1 (en) * | 1991-10-15 | 1993-04-29 | Gastrone, Inc. | Epidermal growth factor therapy for non-gastroduodenal lesions |
| FR2684301B1 (fr) * | 1991-12-02 | 1995-03-24 | Synthelabo | Composition pharmaceutique contenant de l'egf pour le traitement des pathologies bronchopulmonaires. |
| AU678764B2 (en) * | 1992-06-03 | 1997-06-12 | Case Western Reserve University | Bandage for continuous application of biologicals |
| US5618544A (en) * | 1992-08-12 | 1997-04-08 | Bays-Brown Dermatologics, Inc. | Method of decreasing cutaneous senescence |
| US5955430A (en) * | 1993-09-24 | 1999-09-21 | University Of Southern California | Use of angiotensin II fragments and analogs thereof in tissue repair |
| US5624893A (en) * | 1993-10-14 | 1997-04-29 | Alcon Laboratories, Inc. | Pharmaceutical compositions and methods of treatment of the cornea following laser irradiation |
| US5759548A (en) * | 1993-11-30 | 1998-06-02 | Lxr Biotechnology Inc. | Compositions which inhibit apoptosis, methods of purifying the compositions and uses thereof |
| US6048545A (en) * | 1994-06-24 | 2000-04-11 | Biozone Laboratories, Inc. | Liposomal delivery by iontophoresis |
| US5786214A (en) * | 1994-12-15 | 1998-07-28 | Spinal Cord Society | pH-sensitive immunoliposomes and method of gene delivery to the mammalian central nervous system |
| US5904716A (en) * | 1995-04-26 | 1999-05-18 | Gendler; El | Method for reconstituting cartilage tissue using demineralized bone and product thereof |
| US6063757A (en) * | 1995-11-29 | 2000-05-16 | Urso; Richard G. | Wound treatment method with nerve growth factor |
| US6525018B1 (en) | 1999-05-17 | 2003-02-25 | The General Hospital Corp. | Treating eye disorders using intestinal trefoil proteins |
| EP0938548B1 (de) | 1996-11-06 | 2008-08-06 | The Regents of the University of California | Tumor necrosis factor rezeptor abspaltendes enzym, dessen zubereitungen und verwendungen |
| US20050191661A1 (en) * | 1996-11-06 | 2005-09-01 | Tetsuya Gatanaga | Treatment of inflammatory disease by cleaving TNF receptors |
| US6593456B1 (en) * | 1996-11-06 | 2003-07-15 | The Regents Of The University Of California | Tumor necrosis factor receptor releasing enzyme |
| US6495532B1 (en) * | 1997-03-19 | 2002-12-17 | Sky High, Llc | Compositions containing lysophosphotidic acids which inhibit apoptosis and uses thereof |
| US6949528B1 (en) | 1998-03-18 | 2005-09-27 | Goddard John G | Compositions containing lysophosphatidic acids which inhibit apoptosis and uses thereof |
| US7273618B2 (en) | 1998-12-09 | 2007-09-25 | Chiron Corporation | Method for administering agents to the central nervous system |
| DE69923998T2 (de) * | 1998-12-09 | 2006-04-27 | Chiron Corp., Emeryville | Verwendung eines neurologischen wirkstoffes zur herstellung eines medikamentes zur behandlung von erkrankungen des zentralen nervensystems |
| US6541447B1 (en) | 1999-09-01 | 2003-04-01 | B & M Healthcare Technologies, Inc. | Wound healing composition and method for use thereof |
| US20060063738A1 (en) * | 2000-02-28 | 2006-03-23 | Sky High, Llc | Compositions containing lysophosphotidic acids which inhibit apoptosis and uses thereof |
| US7538082B2 (en) | 2001-04-24 | 2009-05-26 | The General Hospital Corporation | Methods and compositions for treating oral and esophageal lesions |
| WO2003015747A1 (en) | 2001-08-13 | 2003-02-27 | Genomed, Llc | Method to treat pulmonary hypoplasia in the newborn |
| EP1482966B1 (de) * | 2002-03-12 | 2014-05-14 | Bio-Click Technologies Ltd | Verfahren und zusammensetzung zur behandlung von hautwunden mit epidermalem wachstumsfaktor |
| JP2006508709A (ja) * | 2002-09-13 | 2006-03-16 | オキュラー サイエンシス インコーポレイテッド | 視力を向上させる器具及び方法 |
| US20050275799A1 (en) * | 2004-03-10 | 2005-12-15 | Marmo J C | Contact lenses, package systems, and method for promoting a healthy epithelium of an eye |
| CN1972643A (zh) | 2004-05-20 | 2007-05-30 | 库柏维景公司 | 用于提高视力的角膜覆盖物和波前像差矫正 |
| US7883520B2 (en) | 2006-04-10 | 2011-02-08 | Forsight Labs, Llc | Corneal epithelial pocket formation systems, components and methods |
| US20090192554A1 (en) | 2008-01-29 | 2009-07-30 | Confluent Surgical, Inc. | Bioabsorbable block copolymer |
| US9283172B2 (en) | 2013-12-13 | 2016-03-15 | Growgene Biotech Inc. | Use of stem cell conditioned medium to induce ZO-1 proteins expression for skin regeneration, repair and firming |
| CN114470312B (zh) * | 2022-01-28 | 2022-12-13 | 福州大学 | 一种无泄漏封包酵母水凝胶及其制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE53166B1 (en) * | 1980-08-05 | 1988-08-03 | Searle & Co | Synthetic urogastrone gene,corresponding plasmid recombinants,transformed cells,production thereof and urogastrone expression |
| EP0092918B1 (de) * | 1982-04-22 | 1988-10-19 | Imperial Chemical Industries Plc | Mittel mit verzögerter Freigabe |
| JPS5965020A (ja) * | 1982-10-04 | 1984-04-13 | J- C R Kk | 点眼剤 |
| DE3382547D1 (de) * | 1983-01-12 | 1992-05-27 | Chiron Corp | Sekretorische expression in eukaryoten. |
| JPS59196820A (ja) * | 1983-04-20 | 1984-11-08 | Nippon Chem Res Kk | ヒト上皮細胞増殖因子の熱処理方法 |
| US4588684A (en) * | 1983-04-26 | 1986-05-13 | Chiron Corporation | a-Factor and its processing signals |
| US4708861A (en) * | 1984-02-15 | 1987-11-24 | The Liposome Company, Inc. | Liposome-gel compositions |
-
1985
- 1985-10-16 DE DE8585905362T patent/DE3585618D1/de not_active Expired - Lifetime
- 1985-10-16 WO PCT/US1985/002024 patent/WO1986002271A1/en active IP Right Grant
- 1985-10-16 EP EP85905362A patent/EP0200757B1/de not_active Expired - Lifetime
- 1985-10-16 AT AT85905362T patent/ATE73345T1/de not_active IP Right Cessation
- 1985-10-16 JP JP60504751A patent/JPH0611709B2/ja not_active Expired - Lifetime
-
1987
- 1987-04-23 US US07/041,695 patent/US4959353A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0200757A4 (de) | 1987-04-10 |
| EP0200757A1 (de) | 1986-11-12 |
| JPS63502985A (ja) | 1988-11-02 |
| DE3585618D1 (de) | 1992-04-16 |
| JPH0611709B2 (ja) | 1994-02-16 |
| EP0200757B1 (de) | 1992-03-11 |
| WO1986002271A1 (en) | 1986-04-24 |
| US4959353A (en) | 1990-09-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| EELA | Cancelled due to lapse of time |